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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

QTRTD1 Gene

protein-coding   GIFtS: 49
GCID: GC03P113724

Queuine TRNA-Ribosyltransferase Domain Containing 1

Microbiology & Infectious Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Queuine TRNA-Ribosyltransferase Domain Containing 11 2
Queuine TRNA-Ribosyltransferase Domain-Containing Protein 12 3
Queuine TRNA-Ribosyltransferase Subunit QTRTD12
EC 2.4.2.293

External Ids:    HGNC: 257711   Entrez Gene: 796912   Ensembl: ENSG000001515767   UniProtKB: Q9H9743   

Export aliases for QTRTD1 gene to outside databases

Previous GC identifers: GC03P115096 GC03P115258 GC03P111150


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for QTRTD1 Gene:
This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric
enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine,
which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may
play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding
multiple isoforms have been observed for this gene. (provided by RefSeq, Feb 2012)

GeneCards Summary for QTRTD1 Gene: 
QTRTD1 (queuine tRNA-ribosyltransferase domain containing 1) is a protein-coding gene. Diseases associated with QTRTD1 include pneumonia. GO annotations related to this gene include queuine tRNA-ribosyltransferase activity and metal ion binding. An important paralog of this gene is QTRT1.

UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974
Function: Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine
for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby
forming the hypermodified nucleoside queuosine (Q)
(7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the QTRTD1 gene promoter:
         Tal-1   Bach2   POU6F1 (c2)   Nkx2-5   Ik-3   NF-AT   E47   NF-AT2   Pax-4a   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidQTRTD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for QTRTD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QTRTD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.31   Ensembl cytogenetic band:  3q13.31   HGNC cytogenetic band: 3q13.31

QTRTD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
QTRTD1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P113724:  view genomic region     (about GC identifiers)

Start:
113,724,680 bp from pter      End:
113,807,269 bp from pter
Size:
82,590 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974 (See protein sequence)
Recommended Name: Queuine tRNA-ribosyltransferase subunit QTRTD1  
Size: 415 amino acids; 46713 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subunit: Interacts with QTRT1 (By similarity)
Subcellular location: Cytoplasm (By similarity). Mitochondrion (By similarity). Note=May associate with the
mitochondrion outer membrane (By similarity)
Secondary accessions: A6NGE9 B7Z472 B7Z5R2 J3KR78 Q6IA59
Alternative splicing: 4 isoforms:  Q9H974-1   Q9H974-2   Q9H974-3   Q9H974-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for QTRTD1: NX_Q9H974

Explore proteomics data for QTRTD1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H974

  • QTRTD1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    QTRTD1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001243764.1  NP_001243765.1  NP_001243766.1  NP_078914.1  

    ENSEMBL proteins: 
     ENSP00000420806   ENSP00000420682   ENSP00000281273   ENSP00000418056   ENSP00000419169  
     ENSP00000419655   ENSP00000418180  

    Human Recombinant Protein Products for QTRTD1: 
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    Novus Biologicals QTRTD1 Protein
    Novus Biologicals QTRTD1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for QTRTD1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--
    GO:0005739mitochondrion ISS--

    QTRTD1 for ontologies           About GeneDecksing



    QTRTD1 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR002616 tRNA_ribo_trans-like

    Graphical View of Domain Structure for InterPro Entry Q9H974

    ProtoNet protein and cluster: Q9H974

    UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974
    Similarity: Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily


    QTRTD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: QTRD1_HUMAN, Q9H974
    Function: Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine
    for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby
    forming the hypermodified nucleoside queuosine (Q)
    (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
    Catalytic activity: Guanine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine

         Enzyme Number (IUBMB): EC 2.4.2.291

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008479contributes to queuine tRNA-ribosyltransferase activity ISS--
    GO:0046872metal ion binding IEA--
         
    QTRTD1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for QTRTD1:
     Cell division defect  Increased S DNA content, incre  Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for QTRTD1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for QTRTD1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for QTRTD1 
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    hsa-miR-4265 hsa-miR-607 hsa-miR-105 hsa-miR-421 hsa-miR-3667-5p hsa-miR-511 hsa-miR-214* hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidQTRTD1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974
    Pathway: tRNA modification; tRNA-queuosine biosynthesis

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for QTRTD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for QTRTD1 (Q9H9743 ENSP000002812734) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALBP027683, ENSP000002958974I2D: score=1 STRING: ENSP00000295897
    IGHA1P018763, ENSP000003749894I2D: score=1 STRING: ENSP00000374989
    IGHG1P018573, ENSP000003749904I2D: score=1 STRING: ENSP00000374990
    WIPI2Q9Y4P83I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006400tRNA modification ----
    GO:0008616queuosine biosynthetic process ISS--

    QTRTD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for QTRTD1 (QTRD1)

    1 HMDB Compound for QTRTD1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Queuine2-amino-5-((((1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-4H-pyrrolo(2,3-d)pyrimidin-4-one (see all 4)72496-59-4--

    Search CenterWatch for drugs/clinical trials and news about QTRTD1 / QTRD1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for QTRTD1 gene (4 alternative transcripts): 
    NM_001256835.1  NM_001256836.1  NM_001256837.1  NM_024638.3  

    Unigene Cluster for QTRTD1:

    Queuine tRNA-ribosyltransferase domain containing 1
    Hs.477162  [show with all ESTs]
    Unigene Representative Sequence: NM_024638
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000472599 ENST00000485050 ENST00000281273(uc003eay.3 uc003eaz.3 uc011biq.2 uc011bir.2)
    ENST00000466050 ENST00000488665 ENST00000479882 ENST00000493014 ENST00000490183
    ENST00000460163 ENST00000482307 ENST00000466870 ENST00000467703(uc003eba.3)
    ENST00000462869 ENST00000483272 ENST00000495782 ENST00000462966
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate QTRTD1 (see all 26):
    hsa-miR-4265 hsa-miR-607 hsa-miR-105 hsa-miR-421 hsa-miR-3667-5p hsa-miR-511 hsa-miR-214* hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidQTRTD1 3' UTR sequence
    Inhib. RNA
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for QTRTD1
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QTRTD1

    Additional mRNA sequence: 

    AK023022.1 AK296938.1 AK299313.1 AL832215.1 AL833709.1 BC034559.2 BC039265.1 CR457296.1 

    10 DOTS entries:

    DT.100749889  DT.309371  DT.106131  DT.92003078  DT.100689019  DT.120867109  DT.75113057  DT.97809317 
    DT.40111843  DT.91868796 

    24/91 AceView cDNA sequences (see all 91):

    CR614436 CA431921 CB044300 BQ426147 AU131204 AA406030 BX091224 BE048722 
    AL833709 AI702965 BU156561 BQ423492 AI890753 NM_024638 AI292226 BM457023 
    AL515410 AW293598 CR595228 AU132268 AK023022 BC039265 AI032526 AA975060 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for QTRTD1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12
    SP1:                          -                                                                       -                           
    SP2:                          -           -                                                                                       
    SP3:                    -     -     -     -     -     -                                   -           -                           
    SP4:                                                                                                                              
    SP5:                                                  -                                                                           


    ECgene alternative splicing isoforms for QTRTD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    QTRTD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTTTATTTA
    QTRTD1 Expression
    About this image


    See QTRTD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for QTRTD1

    SOURCE GeneReport for Unigene cluster: Hs.477162
        SABiosciences Custom PCR Arrays for QTRTD1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QTRTD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for QTRTD1 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Qtrtd11 , 5 queuine tRNA-ribosyltransferase domain containing 11, 5 83.9(n)1
    85.39(a)1
      16 (28.44 cM)5
    1062481  NM_029128.21  NP_083404.21 
     438614075 
    chicken
    (Gallus gallus)
    Aves QTRTD11 queuine tRNA-ribosyltransferase domain containing 1 68.98(n)
    65.26(a)
      418351  NM_001030781.1  NP_001025952.1 
    lizard
    (Anolis carolinensis)
    Reptilia QTRTD16
    Uncharacterized protein
    67(a)
    1 ↔ 1
    3(176478343-176541091)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.158502 Xenopus laevis transcribed sequence with weak similarity more 74.1(n)    CA985617.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.154342 Danio rerio, Similar to hypothetical protein FLJ1296 more 74.28(n)    BC045519.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG34341 CG3434 45.1(n)
    33.16(a)
      39098  NM_140063.4  NP_648320.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tgt-21 Protein TGT-2 43.11(n)
    31.62(a)
      180244  NM_171572.2  NP_741662.1 
    rice
    (Oryza sativa)
    Liliopsida Os10g01419001 hypothetical protein 45.29(n)
    34.24(a)
      4348087  NM_001070681.1  NP_001064146.1 


    ENSEMBL Gene Tree for QTRTD1 (if available)
    TreeFam Gene Tree for QTRTD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for QTRTD1 gene
    QTRT12  

    QTRTD1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/572 SNPs in QTRTD1 are shown (see all 572)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2007342921,2
    C--113774862(+) AAAAA-/AGAGAG 4 -- us2k10--------
    rs1440741361,2
    C--113777500(+) TCAGCC/TTCCGG 4 -- int10--------
    rs1506245131,2
    --113777668(+) CCACCA/GTGCCC 4 -- int10--------
    rs1916073801,2
    --113777717(+) AGCTCA/CATGCA 4 -- int10--------
    rs1821025631,2
    --113777742(+) AGTCCG/TTCAGT 4 -- int10--------
    rs1176389261,2
    C--113777761(+) TATGCA/GTATAC 4 -- int11Minor allele frequency- G:0.01EA 120
    rs783714951,2
    C,F--113777882(+) AAATTT/CTGGAC 4 -- int11Minor allele frequency- C:0.01WA 118
    rs1879301301,2
    --113778000(+) AGGTAC/TGGTGT 4 -- int10--------
    rs622670911,2
    C,F--113778063(+) GACAGC/TCTGTC 4 -- int15Minor allele frequency- T:0.12NA WA EA 362
    rs1924040271,2
    --113778064(+) ACAGCC/TTGTCA 4 -- int10--------

    HapMap Linkage Disequilibrium report for QTRTD1 (113724680 - 113807269 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for QTRTD1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv877353CNV Gain21882294
    nsv877352CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for QTRTD1:    About MalaCards
    pneumonia    


    QTRTD1 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: QTRTD1 (1 document)

    Export disorders for QTRTD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for QTRTD1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with QTRTD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. Characterization of the human tRNA-guanine transglyco sylase: confirmation of the heterodimeric subunit structure. (PubMed id 20354154)1, 9 Chen Y.C....Garcia G.A. (2010)
    4. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases. (PubMed id 21131277)1 Chen Y.C....Garcia G.A. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79691 HGNC: 25771 AceView: QTRTD1 Ensembl:ENSG00000151576 euGenes: HUgn79691
    ECgene: QTRTD1 H-InvDB: QTRTD1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for QTRTD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for QTRTD1 gene:
    Search GeneIP for patents involving QTRTD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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