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QTRTD1 Gene

protein-coding   GIFtS: 50
GCID: GC03P113724

Queuine TRNA-Ribosyltransferase Domain Containing 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Queuine TRNA-Ribosyltransferase Domain Containing 11 2
Queuine TRNA-Ribosyltransferase Domain-Containing Protein 12 3
Queuine TRNA-Ribosyltransferase Subunit QTRTD12
EC 2.4.2.293

External Ids:    HGNC: 257711   Entrez Gene: 796912   Ensembl: ENSG000001515767   UniProtKB: Q9H9743   

Export aliases for QTRTD1 gene to outside databases

Previous GC identifers: GC03P115096 GC03P115258 GC03P111150


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for QTRTD1 Gene:
This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric
enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine,
which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may
play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding
multiple isoforms have been observed for this gene. (provided by RefSeq, Feb 2012)

GeneCards Summary for QTRTD1 Gene:
QTRTD1 (queuine tRNA-ribosyltransferase domain containing 1) is a protein-coding gene. GO annotations related to this gene include queuine tRNA-ribosyltransferase activity. An important paralog of this gene is QTRT1.

UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974
Function: Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine
for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby
forming the hypermodified nucleoside queuosine (Q)
(7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the QTRTD1 gene promoter:
         Tal-1   Bach2   POU6F1 (c2)   Nkx2-5   Ik-3   NF-AT   E47   NF-AT2   Pax-4a   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidQTRTD1 promoter sequence
   Search Chromatin IP Primers for QTRTD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat QTRTD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q13.31   Ensembl cytogenetic band:  3q13.31   HGNC cytogenetic band: 3q13.31

QTRTD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
QTRTD1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P113724:  view genomic region     (about GC identifiers)

Start:
113,724,680 bp from pter      End:
113,807,269 bp from pter
Size:
82,590 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974 (See protein sequence)
Recommended Name: Queuine tRNA-ribosyltransferase subunit QTRTD1  
Size: 415 amino acids; 46713 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subunit: Interacts with QTRT1 (By similarity)
Secondary accessions: A6NGE9 B7Z472 B7Z5R2 J3KR78 Q6IA59
Alternative splicing: 4 isoforms:  Q9H974-1   Q9H974-2   Q9H974-3   Q9H974-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for QTRTD1: NX_Q9H974

Explore proteomics data for QTRTD1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys211
  • Modification sites at PhosphoSitePlus

  • See QTRTD1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001243764.1  NP_001243765.1  NP_001243766.1  NP_078914.1  

    ENSEMBL proteins: 
     ENSP00000420806   ENSP00000420682   ENSP00000281273   ENSP00000418056   ENSP00000419169  
     ENSP00000419655   ENSP00000418180  

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    antibodies-online proteins for QTRTD1 (6 products) 

     
    antibodies-online peptides for QTRTD1

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR028592 QTRTD1
     IPR002616 tRNA_ribo_trans-like

    Graphical View of Domain Structure for InterPro Entry Q9H974

    ProtoNet protein and cluster: Q9H974

    UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974
    Similarity: Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily


    Find genes that share domains with QTRTD1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: QTRD1_HUMAN, Q9H974
    Function: Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine
    for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby
    forming the hypermodified nucleoside queuosine (Q)
    (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
    Catalytic activity: Guanine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine

         Enzyme Number (IUBMB): EC 2.4.2.291

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--
    GO:0008479contributes to queuine tRNA-ribosyltransferase activity ISS--
         
    Find genes that share ontologies with QTRTD1           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for QTRTD1:
     Cell division defect  Increased S DNA content, incre  Increased number of mitotic ce 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for QTRTD1

    miRNA
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    miRTarBase miRNAs that target QTRTD1:
    hsa-mir-361-5p (MIRT044078), hsa-mir-93-3p (MIRT038881), hsa-mir-590-3p (MIRT016170), hsa-mir-193b-3p (MIRT041341)

    Block miRNA regulation of human, mouse, rat QTRTD1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate QTRTD1 (see all 26):
    hsa-miR-4265 hsa-miR-607 hsa-miR-105 hsa-miR-421 hsa-miR-3667-5p hsa-miR-511 hsa-miR-214* hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidQTRTD1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    QTRD1_HUMAN, Q9H974: Cytoplasm (By similarity). Mitochondrion (By similarity). Note=May associate with the
    mitochondrion outer membrane (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion4
    cytosol3
    nucleus2
    cytoskeleton1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--
    GO:0005739mitochondrion ISS--

    Find genes that share ontologies with QTRTD1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    UniProtKB/Swiss-Prot: QTRD1_HUMAN, Q9H974
    Pathway: tRNA modification; tRNA-queuosine biosynthesis

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for QTRTD1
    Interactions:

        Search GeneGlobe Interaction Network for QTRTD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for QTRTD1 (Q9H9743 ENSP000002812734) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALBP027683, ENSP000002958974I2D: score=1 STRING: ENSP00000295897
    IGHA1P018763, ENSP000003749894I2D: score=1 STRING: ENSP00000374989
    IGHG1P018573, ENSP000003749904I2D: score=1 STRING: ENSP00000374990
    WIPI2Q9Y4P83I2D: score=1 
    QTRT1ENSP000002502374STRING: ENSP00000250237
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006400tRNA modification ----
    GO:0008616queuosine biosynthetic process ISS--

    Find genes that share ontologies with QTRTD1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for QTRTD1 (QTRD1)

    1 HMDB Compound for QTRTD1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Queuine2-amino-5-((((1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-4H-pyrrolo(2,3-d)pyrimidin-4-one (see all 4)72496-59-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for QTRTD1 gene (4 alternative transcripts): 
    NM_001256835.1  NM_001256836.1  NM_001256837.1  NM_024638.3  

    Unigene Cluster for QTRTD1:

    Queuine tRNA-ribosyltransferase domain containing 1
    Hs.477162  [show with all ESTs]
    Unigene Representative Sequence: NM_024638
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000472599 ENST00000485050 ENST00000281273(uc003eay.3 uc003eaz.3 uc011biq.2 uc011bir.2)
    ENST00000466050 ENST00000488665 ENST00000479882 ENST00000493014 ENST00000490183
    ENST00000460163 ENST00000482307 ENST00000466870 ENST00000467703(uc003eba.3)
    ENST00000462869 ENST00000483272 ENST00000495782 ENST00000462966
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    Selected qRT-PCR Assays for microRNAs that regulate QTRTD1 (see all 26):
    hsa-miR-4265 hsa-miR-607 hsa-miR-105 hsa-miR-421 hsa-miR-3667-5p hsa-miR-511 hsa-miR-214* hsa-miR-7-1*
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      QuantiFast Probe-based Assays in human, mouse, rat QTRTD1

    Additional mRNA sequence: 

    AK023022.1 AK296938.1 AK299313.1 AL832215.1 AL833709.1 BC034559.2 BC039265.1 CR457296.1 

    10 DOTS entries:

    DT.100749889  DT.309371  DT.106131  DT.92003078  DT.100689019  DT.120867109  DT.75113057  DT.97809317 
    DT.40111843  DT.91868796 

    Selected AceView cDNA sequences (see all 91):

    BM457023 NM_024638 AU132268 BQ426147 AI702965 AL515410 AA406030 BQ423492 
    AL833709 BC039265 BE048722 AU131204 CR614436 AI292226 CA431921 AI890753 
    CB044300 AW293598 BU156561 CR595228 AK023022 BX091224 BC034559 AI032526 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for QTRTD1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12
    SP1:                          -                                                                       -                           
    SP2:                          -           -                                                                                       
    SP3:                    -     -     -     -     -     -                                   -           -                           
    SP4:                                                                                                                              
    SP5:                                                  -                                                                           


    ECgene alternative splicing isoforms for QTRTD1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    QTRTD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTTTATTTA
    QTRTD1 Expression
    About this image

    QTRTD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    QTRTD1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.477162
        Custom PCR Arrays for QTRTD1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QTRTD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for QTRTD1 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Qtrtd11 , 5 queuine tRNA-ribosyltransferase domain containing 11, 5 83.9(n)1
    85.39(a)1
      16 (28.44 cM)5
    1062481  NM_029128.21  NP_083404.21 
     438614075 
    chicken
    (Gallus gallus)
    Aves QTRTD11 queuine tRNA-ribosyltransferase domain containing 1 68.28(n)
    64.32(a)
      418351  NM_001030781.1  NP_001025952.1 
    lizard
    (Anolis carolinensis)
    Reptilia QTRTD16
    queuine tRNA-ribosyltransferase domain containing ...
    66(a)
    1 ↔ 1
    3(176478343-176541091)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.158502 Xenopus laevis transcribed sequence with weak similarity more 74.1(n)    CA985617.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.154342 Danio rerio, Similar to hypothetical protein FLJ1296 more 74.28(n)    BC045519.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG34341 CG3434 44.92(n)
    33.16(a)
      39098  NM_140063.5  NP_648320.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tgt-21 tgt-2 43.17(n)
    31.81(a)
      180244  NM_171572.3  NP_741662.1 
    rice
    (Oryza sativa)
    Liliopsida Os10g01419001 Os10g0141900 45.47(n)
    34.51(a)
      4348087  NM_001070681.1  NP_001064146.1 


    ENSEMBL Gene Tree for QTRTD1 (if available)
    TreeFam Gene Tree for QTRTD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for QTRTD1 gene
    QTRT12  

    Find genes that share paralogs with QTRTD1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for QTRTD1 (see all 572)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2007342921,2
    C--113774862(+) AAAAA-/AGAGAG 4 -- us2k10--------
    rs1440741361,2
    C--113777500(+) TCAGCC/TTCCGG 4 -- int10--------
    rs1506245131,2
    --113777668(+) CCACCA/GTGCCC 4 -- int10--------
    rs1916073801,2
    --113777717(+) AGCTCA/CATGCA 4 -- int10--------
    rs1821025631,2
    --113777742(+) AGTCCG/TTCAGT 4 -- int10--------
    rs1176389261,2
    C--113777761(+) TATGCA/GTATAC 4 -- int11Minor allele frequency- G:0.01EA 120
    rs783714951,2
    C,F--113777882(+) AAATTT/CTGGAC 4 -- int11Minor allele frequency- C:0.01WA 118
    rs1879301301,2
    --113778000(+) AGGTAC/TGGTGT 4 -- int10--------
    rs622670911,2
    C,F--113778063(+) GACAGC/TCTGTC 4 -- int15Minor allele frequency- T:0.12NA WA EA 362
    rs1924040271,2
    --113778064(+) ACAGCC/TTGTCA 4 -- int10--------

    HapMap Linkage Disequilibrium report for QTRTD1 (113724680 - 113807269 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for QTRTD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv877353CNV Gain21882294
    nsv877352CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing QTRTD1
    DNA2.0 Custom Variant and Variant Library Synthesis for QTRTD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with QTRTD1           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: QTRTD1 (1 document)

    Export disorders for QTRTD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for QTRTD1 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with QTRTD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure. (PubMed id 20354154)1, 9 Chen Y.C....Garcia G.A. (RNA 2010)
    4. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases. (PubMed id 21131277)1 Chen Y.C....Garcia G.A. (Nucleic Acids Res. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79691 HGNC: 25771 AceView: QTRTD1 Ensembl:ENSG00000151576 euGenes: HUgn79691
    ECgene: QTRTD1 H-InvDB: QTRTD1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for QTRTD1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for QTRTD1 gene:
    Search GeneIP for patents involving QTRTD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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