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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

QSOX1 Gene

protein-coding   GIFtS: 55
GCID: GC01P180123

quiescin Q6 sulfhydryl oxidase 1

(Previous name: quiescin Q6 )
(Previous symbol: QSCN6)
 Explore 7 diseases affiliated with
QSOX1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for QSOX1    

Aliases
for QSOX1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Quiescin Q6 Sulfhydryl Oxidase 11 2     EC 1.8.3.23 8
QSCN61 2 3     Q62
Quiescin Q61 3     Sulfhydryl Oxidase 12
HQSOX1     

External Ids:    HGNC: 97561   Entrez Gene: 57682   Ensembl: ENSG000001162607   OMIM: 6031205   UniProtKB: O003913   

Export aliases for QSOX1 gene to outside databases

Previous GC identifers: GC01P178391 GC01P151355


Summaries
for QSOX1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for QSOX1:
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families.
The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting
that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms
have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: QSOX1_HUMAN, O00391
Function: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction
of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In
fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation

Gene Wiki entry for QSOX1


Genomic Views
for QSOX1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the QSOX1 gene promoter:
         Spz1   IRF-2   POU2F1   AML1a   POU2F1a   Cart-1   IRF-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: QSOX1 promoter sequence
   Search SABiosciences Chromatin IP Primers for QSOX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QSOX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24   Ensembl cytogenetic band:  1q25.2   HGNC cytogenetic band: 1q24

QSOX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
QSOX1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P180123:  view genomic region     (about GC identifiers)

Start:
 180,123,968 bp from pter      End:
 180,173,165 bp from pter
Size:
 49,198 bases      Orientation:
 plus strand

Proteins
for QSOX1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: QSOX1_HUMAN, O00391 (See protein sequence)
Recommended Name: Sulfhydryl oxidase 1 precursor  
Size: 747 amino acids; 82578 Da
Cofactor: Binds 1 FAD per subunit
Subunit: Monomer
Subcellular location: Isoform 1: Golgi apparatus membrane; Single-pass membrane protein
Subcellular location: Isoform 2: Secreted, extracellular space. Note=Found in the extracellular medium of quiescent
cells but is not found in proliferating cells
Miscellaneous: 'Quiescin Q6' means that it was the sixth clone to be found at a higher level of expression in quiescent
fibroblasts
Sequence caution: Sequence=BAD92517.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
3 PDB 3D structures from and Proteopedia for QSOX1:
3LLI (3D)        3LLK (3D)        3Q6O (3D)    
Secondary accessions: Q59G29 Q5T2X0 Q8TDL6 Q8WVP4
Alternative splicing: 2 isoforms:  O00391-1   O00391-2   

Explore the universe of human proteins at neXtProt for QSOX1: NX_O00391

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O00391

    • 4/6 DME Specific Peptides for QSOX1 (O00391) (see all 6)
     FPKVQWP  SWCGHCI  EDPQFPK  LFHFLTVQA 

    QSOX1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001004128.1  NP_002817.2  

    ENSEMBL proteins: 
     ENSP00000356574   ENSP00000375883   ENSP00000356572   ENSP00000402170  

    Human Recombinant Protein Products: 
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    Novus Biologicals QSOX1 Protein
    Novus Biologicals QSOX1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for QSOX1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA10708601
    GO:0030173integral to Golgi membrane IDA17331072


    QSOX1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for QSOX1

    Protein Domains /
    Families
    for QSOX1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    QSOX1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR017905 ERV/ALR_sulphydryl_oxidase
     IPR012336 Thioredoxin-like_fold
     IPR006863 Evr1_Alr
     IPR013766 Thioredoxin_domain

    Graphical View of Domain Structure for InterPro Entry O00391

    ProtoNet protein and cluster: O00391

    2 Blocks protein families:
    IPB006662 Thioredoxin type domain
    IPB006863 Erv1/Alr


    UniProtKB/Swiss-Prot: QSOX1_HUMAN, O00391
    Similarity: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family
    Similarity: Contains 1 ERV/ALR sulfhydryl oxidase domain
    Similarity: Contains 1 thioredoxin domain


    Function
    for QSOX1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: QSOX1_HUMAN, O00391
    Function: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction
    of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In
    fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation
    Catalytic activity: 2 R'C(R)SH + O(2) = R'C(R)S-S(R)CR' + H(2)O(2)
    Induction: Induced in quiescent cells just as fibroblasts begin to leave the proliferative cycle and enter quiescence

    Enzyme Number (IUBMB): EC 1.8.3.21 2

    miRNA
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    hsa-miR-495 hsa-miR-7-2* hsa-miR-4290 hsa-miR-3692 hsa-miR-124 hsa-miR-7-1* hsa-miR-506 hsa-miR-32*
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for QSOX1

    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003756protein disulfide isomerase activity IGI17331072
    GO:0009055electron carrier activity ----
    GO:0015035protein disulfide oxidoreductase activity ----
    GO:0016971flavin-linked sulfhydryl oxidase activity IGI17331072


    QSOX1 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for QSOX1:
     Decreased Salmonella enterica   Increased cell death in breast  Increased gamma-H2AX phosphory 


    Pathways & Interactions
    for QSOX1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for QSOX1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for QSOX1 (O003912, 3 ENSP000003565744) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2862369 I2D: score=2 STRING: ENSP00000357292
    SCN2BENSP000002789474STRING: ENSP00000278947
    UBE2D2ENSP000003817174STRING: ENSP00000381717
    BEGAINENSP000003473014STRING: ENSP00000347301
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding IGI17331072
    GO:0006662glycerol ether metabolic process ----
    GO:0045454cell redox homeostasis IEA--


    QSOX1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for QSOX1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for QSOX1

    3 HMDB Compounds for QSOX1    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    OxygenOxygen (see all 5)7782-44-7--
    WaterDihydrogen oxide (see all 2)7732-18-5--
    Search CenterWatch for drugs/clinical trials and news about QSOX1 

    Transcripts
    for QSOX1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for QSOX1 gene (2 alternative transcripts): 
    NM_001004128.2  NM_002826.4  

    Unigene Cluster for QSOX1:

    Quiescin Q6 sulfhydryl oxidase 1
    Hs.518374  [show with all ESTs]
    Unigene Representative Sequence: NM_002826
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367602(uc001gny.3 uc001gnz.3) ENST00000392029 ENST00000367600
    ENST00000443059

    miRNA
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    hsa-miR-495 hsa-miR-7-2* hsa-miR-4290 hsa-miR-3692 hsa-miR-124 hsa-miR-7-1* hsa-miR-506 hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmid: QSOX1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: QSOX1
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    Clone
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QSOX1

    Additional cDNA sequence: 

    AB209280.1 AF361868.1 AK290842.1 AK290887.1 AY358941.1 BC017692.1 BC100023.1 U97276.2 

    24/40 DOTS entries (see all 40):

    DT.100829879  DT.99973359  DT.92440983  DT.100059508  DT.102840166  DT.86855929  DT.86841789  DT.97759904 
    DT.100724595  DT.101967478  DT.99968131  DT.102840180  DT.100691414  DT.121434083  DT.100053977  DT.102844889 
    DT.102840170  DT.102840174  DT.91750186  DT.92440981  DT.102840182  DT.100654003  DT.100654006  DT.100654010 

    24/1123 AceView cDNA sequences (see all 1123):

    BM771248 CF125412 CF125436 BM772993 NM_001004128 AI358823 BM561487 AI469130 
    AW241861 AI910564 BU733310 BQ920061 CB528946 BQ878559 BQ953099 BU628864 
    AA947617 CF125626 CF125424 BM771261 CF132176 CO247678 CF132132 CA390872 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for QSOX1 (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14a · 14b
    SP1:              -                                                                                         -     -               
    SP2:              -                                                                                                               
    SP3:                          -                                                                                                   
    SP4:              -     -     -     -     -     -     -                                                                           
    SP5:        -     -                                                                                                               


    ECgene alternative splicing isoforms for QSOX1

    Expression
    for QSOX1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    QSOX1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTTGATTCCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    QSOX1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See QSOX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for QSOX1

    SOURCE GeneReport for Unigene cluster: Hs.518374

    UniProtKB/Swiss-Prot: QSOX1_HUMAN, O00391
    Tissue specificity: Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and
    kidney

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    In Situ
    Assay Products:     
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    Orthologs
    for QSOX1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for QSOX1 gene from 8/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves QSOX11 quiescin Q6 sulfhydryl oxidase 1 62.29(n)
    54.4(a)    		   373914  NM_204125.1  NP_989456.1 
    lizard
    (Anolis carolinensis)    		 Reptilia QSOX16
    		 --
    		 42(a)
    		 1 ↔ 1
    		 4(70392296-70481471)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia BX720504.12   -- 78.47(n)    BX720504.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii sbcb8402 sbcb840 71.44(n)   378857  57048593 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG46701 CG4670 46.5(n)
    34.4(a)    		   36464  NM_137008.2  NP_610852.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea T10H10.21 Protein T10H10.2 41.2(n)
    33.68(a)    		   180538  NM_076018.2  NP_508419.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons QSOX26
    ATQSOX16
    		 quiescin-sulfhydryl oxidase 1
    		 21(a)
    20(a)
    		 many ↔ many
    many ↔ many
    		 2(139331-142560)
    1(5173097-5176223)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 OsQSOXL1 quiescin-sulfhydryl oxidase-like OsQSOXL...
    		 19(a)
    		 1 → many
    		 5(27411401-27416420)


    ENSEMBL Gene Tree for QSOX1 (if available)
    TreeFam Gene Tree for QSOX1 (if available) 

    Paralogs
    for QSOX1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for QSOX1 gene
    QSOX22  
    4 SIMAP similar genes for QSOX1 using alignment to 3 protein entries:     QSOX1_HUMAN (see all proteins):
    QSCN6    QSOX2    PDIA3    PDIA5

    QSOX1 for paralogs           About GeneDecksing



    Genomic Variants
    for QSOX1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/943 NCBI SNPs in QSOX1 are shown (see all 943)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1155096961,2
    		F,--180122086(+) CCTAAC/TCCAGA 2 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1124412271,2
    		--180122339(+) AGTGCC/TGCAAT 2 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs115895191,2
    		C,F,A,H,--180122390(+) CAAGGC/TCTATC 2 -- us2k19Minor allele frequency- T:0.48NA WA EA 370
    rs1509612191,2
    		--180122468(+) ATGTCC/GTTGTT 2 -- us2k10--------
    rs75301681,2
    		C,F,A,--180122575(+) AGCACT/CACATT 2 -- us2k17Minor allele frequency- C:0.20NA WA CSA EA 366
    rs75277331,2
    		C,H,--180122578(+) ACTACG/ATTCGA 2 -- us2k112Minor allele frequency- A:0.05NA WA CSA EA 256
    rs1406615601,2
    		--180122579(+) CTACAC/TTCGAG 2 -- us2k10--------
    rs75162571,2
    		C,F,A,H,--180122812(+) CACCTC/TCTCTG 2 -- us2k117Minor allele frequency- T:0.12NS EA NA WA CSA 1968
    rs1154002091,2
    		--180122882(+) ATTTAC/GTTATG 2 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1851880771,2
    		--180122967(+) TATACA/CTAAAC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for QSOX1 (180123968 - 180173165 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for QSOX1
         1 CNV: 4264

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    Disorders / Diseases
    for QSOX1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    QSOX1 for disorders           About GeneDecksing

    OMIM gene information: 603120    OMIM disorders: --

    7 diseases for QSOX1:    About MalaCards
    intrahepatic cholangiocarcinoma    insulin resistance    cholangiocarcinoma    prostate cancer
    prostatitis    breast cancer    ataxia

    2 Novoseek disease relationships for QSOX1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate cancer 26.8 1 9878249 (1)
    tumors 0 1 19597465 (1)


    Export disorders for QSOX1 gene to outside databases

    Publications
    for QSOX1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for QSOX1 gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with QSOX1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1. (PubMed id 9878249)1, 2, 3, 9 Coppock D.L.... Gilleran S. (1998)
    2. Regulation of the quiescence-induced genes: quiescin Q6, decorin, and ribosomal protein S29. (PubMed id 10708601)1, 2, 9 Coppock D.L.... Cina-Poppe D.A. (2000)
    3. Homology between egg white sulfhydryl oxidase and quiescin Q6 defines a new class of flavin-linked sulfhydryl oxidases. (PubMed id 10542195)1, 2, 9 Hoober K.L.... Thorpe C. (1999)
    4. Preferential gene expression in quiescent human lung fibroblasts. (PubMed id 8396966)1, 3, 9 Coppock D.L....Gilleran S. (1993)
    5. QSOX contains a pseudo-dimer of functional and degene rate sulfhydryl oxidase domains. (PubMed id 20211621)1, 2 Alon A....Fass D. (2010)
    6. Human quiescin-sulfhydryl oxidase, QSOX1: probing internal redox steps by mutagenesis. (PubMed id 18393449)1, 2 Heckler E.J....Thorpe C. (2008)
    7. Intracellular catalysis of disulfide bond formation by the human sulfhydryl oxidase, QSOX1. (PubMed id 17331072)1, 2 Chakravarthi S.... Bulleid N.J. (2007)
    8. Identification and expression of a new splicing variant of FAD- sulfhydryl oxidase in adult rat brain. (PubMed id 16806532)1, 2 Radom J.... Jouvenot M. (2006)
    9. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    10. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)

    External Searches for QSOX1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing QSOX1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5768 HGNC: 9756 AceView: QSCN6 Ensembl:ENSG00000116260 euGenes: HUgn5768
    ECgene: QSOX1 H-InvDB: QSOX1

    Other Databases showing QSOX1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing QSOX1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for QSOX1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for QSOX1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for QSOX1 gene:
    Search GeneIP for patents involving QSOX1

    GeneCards and IP:
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