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Aliases for QSER1 Gene

Aliases for QSER1 Gene

  • Glutamine And Serine Rich 1 2 3

External Ids for QSER1 Gene

Previous GeneCards Identifiers for QSER1 Gene

  • GC11P032609

Summaries for QSER1 Gene

GeneCards Summary for QSER1 Gene

QSER1 (Glutamine And Serine Rich 1) is a Protein Coding gene. An important paralog of this gene is PRR12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for QSER1 Gene

Genomics for QSER1 Gene

Regulatory Elements for QSER1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for QSER1 Gene

Start:
32,893,178 bp from pter
End:
32,993,316 bp from pter
Size:
100,139 bases
Orientation:
Plus strand

Genomic View for QSER1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for QSER1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for QSER1 Gene

Proteins for QSER1 Gene

  • Protein details for QSER1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2KHR3-QSER1_HUMAN
    Recommended name:
    Glutamine and serine-rich protein 1
    Protein Accession:
    Q2KHR3
    Secondary Accessions:
    • Q6ZU30
    • Q6ZUR5

    Protein attributes for QSER1 Gene

    Size:
    1735 amino acids
    Molecular mass:
    189972 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI12936.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAC86397.1; Type=Erroneous termination; Positions=1555; Note=Translated as Leu.; Evidence={ECO:0000305};

    Alternative splice isoforms for QSER1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for QSER1 Gene

Proteomics data for QSER1 Gene at MOPED

Post-translational modifications for QSER1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for QSER1 Gene

No data available for DME Specific Peptides for QSER1 Gene

Domains for QSER1 Gene

Protein Domains for QSER1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for QSER1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with QSER1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for QSER1 Gene

Function for QSER1 Gene

Phenotypes for QSER1 Gene

GenomeRNAi human phenotypes for QSER1:
genes like me logo Genes that share phenotypes with QSER1: view

Animal Model Products

CRISPR Products

miRNA for QSER1 Gene

miRTarBase miRNAs that target QSER1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for QSER1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for QSER1 Gene

Localization for QSER1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for QSER1 Gene COMPARTMENTS Subcellular localization image for QSER1 gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for QSER1 Gene

Pathways for QSER1 Gene

SuperPathways for QSER1 Gene

No Data Available

Interacting Proteins for QSER1 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000382241%0d%0a9606.ENSP00000405965%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000323588%0d%0a9606.ENSP00000360532%0d%0a
Selected Interacting proteins: ENSP00000382241 for QSER1 Gene via STRING

Gene Ontology (GO) - Biological Process for QSER1 Gene

None

No data available for Pathways by source for QSER1 Gene

Transcripts for QSER1 Gene

Unigene Clusters for QSER1 Gene

Glutamine and serine rich 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for QSER1

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for QSER1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for QSER1 Gene

No ASD Table

Relevant External Links for QSER1 Gene

GeneLoc Exon Structure for
QSER1
ECgene alternative splicing isoforms for
QSER1

Expression for QSER1 Gene

mRNA expression in normal human tissues for QSER1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for QSER1 Gene

SOURCE GeneReport for Unigene cluster for QSER1 Gene Hs.369368

genes like me logo Genes that share expressions with QSER1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for QSER1 Gene

Orthologs for QSER1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for QSER1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia QSER1 35
  • 99.58 (n)
  • 99.37 (a)
QSER1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia QSER1 35
  • 91.29 (n)
  • 89.61 (a)
QSER1 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia QSER1 35
  • 92.41 (n)
  • 91.73 (a)
QSER1 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Qser1 35
  • 86.08 (n)
  • 81.98 (a)
Qser1 16
Qser1 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia QSER1 36
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia QSER1 36
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Qser1 35
  • 85.15 (n)
  • 81.34 (a)
chicken
(Gallus gallus)
Aves QSER1 35
  • 75.69 (n)
  • 71.69 (a)
QSER1 36
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia QSER1 36
  • 60 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.2293 35
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100036640 35
  • 66.69 (n)
  • 62.31 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100330496 35
  • 60.8 (n)
  • 58.16 (a)
qser1 36
  • 42 (a)
OneToOne
Species with no ortholog for QSER1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for QSER1 Gene

ENSEMBL:
Gene Tree for QSER1 (if available)
TreeFam:
Gene Tree for QSER1 (if available)

Paralogs for QSER1 Gene

Paralogs for QSER1 Gene

genes like me logo Genes that share paralogs with QSER1: view

Variants for QSER1 Gene

Sequence variations from dbSNP and Humsavar for QSER1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1022586 - 32,932,798(-) AGTTA(C/T)AGTCT missense, reference
rs1337757 -- 32,949,467(-) CATGG(A/G)TACAT intron-variant
rs1556802 -- 32,956,624(+) TGACC(C/T)TGTGG intron-variant
rs1961247 -- 32,927,468(+) AGTGG(C/T)GTGAT intron-variant
rs1961248 -- 32,927,491(+) CAACC(C/T)CCACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for QSER1 Gene

Variant ID Type Subtype PubMed ID
essv7540 CNV CNV 17122850
essv6421 CNV CNV 17122850
esv34742 CNV Gain 17911159
nsv897190 CNV Gain 21882294
nsv38614 CNV Loss 16902084
dgv1065n71 CNV Gain 21882294

Relevant External Links for QSER1 Gene

HapMap Linkage Disequilibrium report
QSER1
Human Gene Mutation Database (HGMD)
QSER1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for QSER1 Gene

Disorders for QSER1 Gene

Relevant External Links for QSER1

Genetic Association Database (GAD)
QSER1
genes like me logo Genes that share disorders with QSER1: view

No data available for UniProtKB/Swiss-Prot for QSER1 Gene

Publications for QSER1 Gene

  1. Genomewide association study for onset age in Parkinson disease. (PMID: 19772629) Latourelle J.C. … . (BMC Med. Genet. 2009) 3 48
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. System-wide changes to SUMO modifications in response to heat shock. (PMID: 19471022) Golebiowski F. … Hay R.T. (Sci Signal 2009) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for QSER1 Gene

Sources for QSER1 Gene

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