QSER1 Gene
protein-coding GIFtS: 37
GCID: GC11P032905
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|
glutamine and serine rich 1
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Aliases
for QSER1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Glutamine And Serine Rich 11 2 | | FLJ219241 | | Glutamine And Serine-Rich Protein 12 |
Export aliases for QSER1 gene to outside databasesPrevious GC identifer: GC11P032609 |
Summaries
for QSER1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for QSER1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the QSER1 gene promoter:
Max1 Elk-1 AP-1 FOXD3 RelA c-Ets-1 HEN1 FOXJ2 (long isoform) FOXJ2 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for QSER1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QSER1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p13 Ensembl cytogenetic band: 11p13 HGNC cytogenetic band: 11p13QSER1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P032905: view genomic region
(about GC identifiers)
Start:
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32,914,724 bp from pter |
End:
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33,014,862 bp from pter |
Size:
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100,139 bases |
Orientation:
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plus strand |
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Proteins
for QSER1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: QSER1_HUMAN, Q2KHR3 (See
protein sequence)Recommended Name: Glutamine and serine-rich protein 1 Size: 1735 amino acids; 189972 Da
Sequence caution: Sequence=AAI12936.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=BAC86397.1; Type=Erroneous termination; Positions=1555; Note=Translated as Leu;
Secondary accessions: Q6ZU30 Q6ZUR5Alternative splicing: 2 isoforms: Q2KHR3-1 Q2KHR3-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for QSER1: NX_Q2KHR3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q2KHR3
QSER1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001070254.1
ENSEMBL proteins: ENSP00000382241 ENSP00000432766 ENSP00000436870 ENSP00000432136
Human Recombinant Protein Products for QSER1:
QSER1 Antibody Products:
Assay Products for QSER1: |
Protein
Domains /
Families
for QSER1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
QSER1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q2KHR3ProtoNet protein and cluster: Q2KHR3 |
Function
for QSER1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
3 GenomeRNAi human phenotypes for QSER1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QSER1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QSER1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: QSER1 (NM_001076786) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for QSER1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat QSER1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QSER1 |
|
Pathways & Interactions
for QSER1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for QSER1
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for QSER1 (ENSP000003822414) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for QSER1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for QSER1
Search CenterWatch for drugs/clinical trials and news about QSER1
|
Transcripts
for QSER1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for QSER1 gene (2 alternative transcripts): NM_001076786.1 NM_024774.2 Unigene Cluster for QSER1: Glutamine and serine rich 1 Hs.369368 [show with all ESTs]Unigene Representative Sequence: NM_0010767866 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000399302(uc001mty.3) ENST00000527250 ENST00000527788(uc001mua.3 uc001mtz.1)
ENST00000528155 ENST00000524678 ENST00000528034
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QSER1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QSER1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: QSER1 (NM_001076786) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for QSER1 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat QSER1 |
Additional cDNA sequence: AK025577.1 AK055185.1 AK095528.1 AK123858.1 AK125391.1 AK125902.1 AK126023.1 AL834141.1 BC013746.1 BC112935.1 6 DOTS entries: DT.97770969 DT.101982980 DT.438703 DT.100734925 DT.100845821 DT.120705306 24/163 AceView cDNA sequences (see all 163): CA430191 AW015318 BQ222001 NM_024774 AI061251 AK126023 CB159064 AA136884 BQ272039 AI076404 AA764828 AK125902 AA905517 BU170648 CB140386 AI903739 BE673053 AI149869 BM263943 AA749230 AL699927 Z40582 BF056981 AW168575
GeneLoc Exon Structure
|
Expression
for QSER1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| QSER1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTAGCAAA
About this image
See QSER1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for QSER1
SOURCE GeneReport for Unigene cluster: Hs.369368
SABiosciences Custom PCR Arrays for QSER1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for QSER1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat QSER1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat QSER1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QSER1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QSER1 |
Orthologs
for QSER1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for QSER1 gene from 4/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
QSER11 |
glutamine and serine rich 1 |
75.43(n)
71.53(a) |
|
421599 NM_001199414.1 NP_001186343.1 |
lizard
(Anolis carolinensis) |
Reptilia |
QSER16 |
-- |
63(a) |
1 ↔ 1 |
1(61418599-61440330) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.22932 |
Xenopus laevis transcribed sequence with weak similarity more |
77.49(n) |
|
48042007 |
zebrafish
(Danio rerio) |
Actinopterygii |
qser16 |
glutamine and serine rich 1 |
43(a) |
1 ↔ 1 |
18(44091481-44111970) |
ENSEMBL Gene Tree for QSER1 (if available)
TreeFam Gene Tree for QSER1 (if available) |
Paralogs
for QSER1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for QSER1 gene
- PRR122
QSER1 for paralogs About GeneDecksing
|
Genomic Variants
for QSER1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for QSER1 (32914724 - 33014862 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for QSER1
4 CNVs: 8685 2915 3843 5624 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing QSER1 |
|
Disorders
/ Diseases
for QSER1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for QSER1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for QSER1 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with QSER1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
- Purification and identification of endogenous polySUMO conjugates. (PubMed id 21252943)1 Bruderer R....Hay R.T. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
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External Searches for QSER1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing QSER1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing QSER1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing QSER1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for QSER1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for QSER1 gene:
Search GeneIP for patents involving QSER1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for QSER1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for QSER1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for QSER1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for QSER1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for QSER1 | | OriGene 3'-UTR Clone for QSER1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QSER1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QSER1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for QSER1 | | OriGene Custom Protein Services for QSER1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat QSER1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing QSER1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QSER1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat QSER1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QSER1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat QSER1 |
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 |  |  |  | |
| | | | Search Tocris compounds for QSER1 |
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 | | | QSER1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QSER1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for QSER1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat QSER1 |
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