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Aliases for QSER1 Gene

Aliases for QSER1 Gene

  • Glutamine And Serine Rich 1 2 3 5

External Ids for QSER1 Gene

Previous GeneCards Identifiers for QSER1 Gene

  • GC11P032609

Summaries for QSER1 Gene

GeneCards Summary for QSER1 Gene

QSER1 (Glutamine And Serine Rich 1) is a Protein Coding gene. An important paralog of this gene is PRR12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for QSER1 Gene

Genomics for QSER1 Gene

Regulatory Elements for QSER1 Gene

Enhancers for QSER1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around QSER1 on UCSC Golden Path with GeneCards custom track

Promoters for QSER1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for QSER1 Gene

32,893,178 bp from pter
32,993,316 bp from pter
100,139 bases
Plus strand

Genomic View for QSER1 Gene

Genes around QSER1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
QSER1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for QSER1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for QSER1 Gene

Proteins for QSER1 Gene

  • Protein details for QSER1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glutamine and serine-rich protein 1
    Protein Accession:
    Secondary Accessions:
    • Q6ZU30
    • Q6ZUR5

    Protein attributes for QSER1 Gene

    1735 amino acids
    Molecular mass:
    189972 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI12936.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAC86397.1; Type=Erroneous termination; Positions=1555; Note=Translated as Leu.; Evidence={ECO:0000305};

    Alternative splice isoforms for QSER1 Gene


neXtProt entry for QSER1 Gene

Post-translational modifications for QSER1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for QSER1 Gene

No data available for DME Specific Peptides for QSER1 Gene

Domains & Families for QSER1 Gene

Protein Domains for QSER1 Gene


Suggested Antigen Peptide Sequences for QSER1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with QSER1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for QSER1 Gene

Function for QSER1 Gene

Phenotypes for QSER1 Gene

genes like me logo Genes that share phenotypes with QSER1: view

Animal Model Products

CRISPR Products

miRNA for QSER1 Gene

miRTarBase miRNAs that target QSER1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for QSER1 Gene

Localization for QSER1 Gene

Subcellular locations from

Jensen Localization Image for QSER1 Gene COMPARTMENTS Subcellular localization image for QSER1 gene
Compartment Confidence
cytosol 3
nucleus 3
lysosome 1
mitochondrion 1
vacuole 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for QSER1 Gene

Pathways & Interactions for QSER1 Gene

SuperPathways for QSER1 Gene

No Data Available

Interacting Proteins for QSER1 Gene

Gene Ontology (GO) - Biological Process for QSER1 Gene


No data available for Pathways by source and SIGNOR curated interactions for QSER1 Gene

Drugs & Compounds for QSER1 Gene

No Compound Related Data Available

Transcripts for QSER1 Gene

Unigene Clusters for QSER1 Gene

Glutamine and serine rich 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for QSER1 Gene

No ASD Table

Relevant External Links for QSER1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for QSER1 Gene

mRNA expression in normal human tissues for QSER1 Gene

Protein differential expression in normal tissues from HIPED for QSER1 Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for QSER1 Gene

Protein tissue co-expression partners for QSER1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of QSER1 Gene:


SOURCE GeneReport for Unigene cluster for QSER1 Gene:

genes like me logo Genes that share expression patterns with QSER1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for QSER1 Gene

Orthologs for QSER1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for QSER1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia QSER1 34
  • 91.29 (n)
  • 89.61 (a)
QSER1 35
  • 89 (a)
(Canis familiaris)
Mammalia QSER1 34
  • 92.41 (n)
  • 91.73 (a)
QSER1 35
  • 92 (a)
(Mus musculus)
Mammalia Qser1 34
  • 86.08 (n)
  • 81.98 (a)
Qser1 16
Qser1 35
  • 80 (a)
(Pan troglodytes)
Mammalia QSER1 34
  • 99.58 (n)
  • 99.37 (a)
QSER1 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Qser1 34
  • 85.15 (n)
  • 81.34 (a)
(Monodelphis domestica)
Mammalia QSER1 35
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia QSER1 35
  • 73 (a)
(Gallus gallus)
Aves QSER1 34
  • 75.69 (n)
  • 71.69 (a)
QSER1 35
  • 70 (a)
(Anolis carolinensis)
Reptilia QSER1 35
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100036640 34
  • 66.69 (n)
  • 62.31 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.2293 34
(Danio rerio)
Actinopterygii LOC100330496 34
  • 60.8 (n)
  • 58.16 (a)
qser1 35
  • 42 (a)
Species where no ortholog for QSER1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for QSER1 Gene

Gene Tree for QSER1 (if available)
Gene Tree for QSER1 (if available)

Paralogs for QSER1 Gene

Paralogs for QSER1 Gene

genes like me logo Genes that share paralogs with QSER1: view

Variants for QSER1 Gene

Sequence variations from dbSNP and Humsavar for QSER1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs2297781 - 32,933,576(+) TAACC(A/G)ACAAA reference, missense
rs7940077 - 32,934,698(+) AGAGA(A/G)TGCTA reference, missense
rs16923676 - 32,953,976(+) CAGTA(A/G)ATATT downstream-variant-500B, reference, missense
rs1022586 - 32,932,798(-) AGTTA(C/T)AGTCT reference, missense
rs1337757 -- 32,949,467(-) CATGG(A/G)TACAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for QSER1 Gene

Variant ID Type Subtype PubMed ID
esv2759815 CNV gain 17122850
esv2762904 CNV gain 21179565
esv34742 CNV gain 17911159
esv3579466 CNV loss 25503493
nsv1040484 CNV gain 25217958
nsv1113375 CNV deletion 24896259
nsv38614 CNV deletion 16902084

Variation tolerance for QSER1 Gene

Residual Variation Intolerance Score: 39.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.30; 70.49% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for QSER1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for QSER1 Gene

Disorders for QSER1 Gene

Relevant External Links for QSER1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for QSER1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for QSER1 Gene

Publications for QSER1 Gene

  1. Genomewide association study for onset age in Parkinson disease. (PMID: 19772629) Latourelle J.C. … . (BMC Med. Genet. 2009) 3 46 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 65
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65

Products for QSER1 Gene

Sources for QSER1 Gene

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