QRICH2 Gene
protein-coding GIFtS: 39
GCID: GC17M074262
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glutamine rich 2
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Aliases
for QRICH2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Glutamine Rich 21 2 | | DKFZP434P03161 | | Glutamine-Rich Protein 22 |
Export aliases for QRICH2 gene to outside databasesPrevious GC identifers: GC17M071782 GC17M069698 |
Summaries
for QRICH2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for QRICH2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the QRICH2 gene promoter:
AhR PPAR-gamma1 GATA-3 CUTL1 STAT5A PPAR-gamma2 Arnt YY1
Other transcription factors
Search SABiosciences Chromatin IP Primers for QRICH2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QRICH2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.1QRICH2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M074262: view genomic region
(about GC identifiers)
Start:
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74,270,130 bp from pter |
End:
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74,303,761 bp from pter |
Size:
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33,632 bases |
Orientation:
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minus strand |
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Proteins
for QRICH2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: QRIC2_HUMAN, Q9H0J4 (See
protein sequence)Recommended Name: Glutamine-rich protein 2 Size: 1663 amino acids; 180827 Da
Sequence caution: Sequence=BAB71667.1; Type=Erroneous initiation;
Secondary accessions: A2RRE1 Q96LM3Alternative splicing: 3 isoforms: Q9H0J4-1 Q9H0J4-2 Q9H0J4-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for QRICH2: NX_Q9H0J4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H0J4
QRICH2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115510.1
ENSEMBL proteins: ENSP00000262765 ENSP00000394461 ENSP00000432679 ENSP00000433329
Human Recombinant Protein Products:
QRICH2 Antibody Products:
Assay Products for QRICH2: |
Protein
Domains /
Families
for QRICH2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9H0J4 |
Function
for QRICH2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QRICH2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QRICH2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: QRICH2 (NM_032134) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for QRICH2 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat QRICH2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QRICH2 |
2 GenomeRNAi human phenotypes for QRICH2:
|
Pathways & Interactions
for QRICH2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for QRICH2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/9 Interacting proteins for QRICH2 (Q9H0J43 ENSP000002627654) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
|
Drugs & Compounds
for QRICH2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for QRICH2
Search CenterWatch for drugs/clinical trials and news about QRICH2 / QRIC2
|
Transcripts
for QRICH2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for QRICH2 gene: NM_032134.1 Unigene Cluster for QRICH2: Glutamine rich 2 Hs.252739 [show with all ESTs]Unigene Representative Sequence: AL1367744 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000262765(uc002jrd.1 uc010dgw.1) ENST00000447564 ENST00000524722
ENST00000532549
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QRICH2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QRICH2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: QRICH2 (NM_032134) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for QRICH2 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat QRICH2 |
Additional cDNA sequence: AK058102.1 AL136774.1 BC131559.1 4 DOTS entries: DT.427639 DT.100680520 DT.40115274 DT.65284357 24/27 AceView cDNA sequences (see all 27): AL136774 CD515863 NM_032134 BX280937 BX441416 BX451481 BI086721 AI870674 BQ028287 AK058102 BQ012444 BX451482 AW292249 BX451499 AL040290 CD633692 CD633684 AI185550 AA161125 BM171668 R62474 CD633690 T97147 T85653
GeneLoc Exon Structure
|
Expression
for QRICH2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| QRICH2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTCCTGGGG
About this image
See QRICH2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for QRICH2
SOURCE GeneReport for Unigene cluster: Hs.252739
SABiosciences Custom PCR Arrays for QRICH2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for QRICH2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat QRICH2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat QRICH2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QRICH2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QRICH2 |
Orthologs
for QRICH2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for QRICH2 gene from 3/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
QRICH26 |
Uncharacterized protein |
29(a) |
1 ↔ 1 |
18(4454392-4455903) |
lizard
(Anolis carolinensis) |
Reptilia |
QRICH26 |
-- |
60(a) |
1 ↔ 1 |
2(112471964-112494244) |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
17(a) |
1 → many |
Group6.15(186949-192215) |
ENSEMBL Gene Tree for QRICH2 (if available)
TreeFam Gene Tree for QRICH2 (if available) |
Paralogs
for QRICH2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for QRICH2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for QRICH2 (74270130 - 74303761 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for QRICH2
3 CNVs: 73019 102538 5032 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing QRICH2 |
|
Disorders
/ Diseases
for QRICH2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for QRICH2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for QRICH2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with QRICH2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. (PubMed id 19367720)2 Carrascal M.... Abian J. (2008)
- Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for QRICH2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing QRICH2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing QRICH2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing QRICH2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for QRICH2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for QRICH2 gene:
Search GeneIP for patents involving QRICH2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for QRICH2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for QRICH2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for QRICH2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for QRICH2 | | | OriGene Protein Over-expression Lysate for QRICH2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for QRICH2 | | OriGene 3'-UTR Clone for QRICH2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QRICH2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QRICH2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for QRICH2 | | OriGene Custom Protein Services for QRICH2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat QRICH2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing QRICH2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QRICH2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat QRICH2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QRICH2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat QRICH2 |
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 |  |  |  | |
| | | | Search Tocris compounds for QRICH2 |
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 | | | QRICH2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QRICH2 |
|  |  |  | | | | Search ThermoFisher Antibodies for QRICH2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat QRICH2 |
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