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Aliases for QRICH1 Gene

Aliases for QRICH1 Gene

  • Glutamine Rich 1 2 3 5
  • Glutamine-Rich 1 2

External Ids for QRICH1 Gene

Previous GeneCards Identifiers for QRICH1 Gene

  • GC03M049043
  • GC03M049044
  • GC03M049046
  • GC03M049048
  • GC03M049051
  • GC03M049067
  • GC03M049074
  • GC03M049081
  • GC03M049086

Summaries for QRICH1 Gene

GeneCards Summary for QRICH1 Gene

QRICH1 (Glutamine Rich 1) is a Protein Coding gene. An important paralog of this gene is ZMYM4.

Gene Wiki entry for QRICH1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for QRICH1 Gene

Genomics for QRICH1 Gene

Regulatory Elements for QRICH1 Gene

Enhancers for QRICH1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around QRICH1 on UCSC Golden Path with GeneCards custom track

Promoters for QRICH1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around QRICH1 on UCSC Golden Path with GeneCards custom track

Genomic Location for QRICH1 Gene

Chromosome:
3
Start:
49,029,707 bp from pter
End:
49,094,363 bp from pter
Size:
64,657 bases
Orientation:
Minus strand

Genomic View for QRICH1 Gene

Genes around QRICH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
QRICH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for QRICH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for QRICH1 Gene

Proteins for QRICH1 Gene

  • Protein details for QRICH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2TAL8-QRIC1_HUMAN
    Recommended name:
    Glutamine-rich protein 1
    Protein Accession:
    Q2TAL8
    Secondary Accessions:
    • Q4G0F7
    • Q7L621
    • Q8TEA5

    Protein attributes for QRICH1 Gene

    Size:
    776 amino acids
    Molecular mass:
    86436 Da
    Quaternary structure:
    No Data Available

neXtProt entry for QRICH1 Gene

Post-translational modifications for QRICH1 Gene

  • Ubiquitination at Lys 28, Lys 489, Lys 495, and Lys 712
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for QRICH1 Gene

Domains & Families for QRICH1 Gene

Protein Domains for QRICH1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for QRICH1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q2TAL8

UniProtKB/Swiss-Prot:

QRIC1_HUMAN :
  • Contains 1 CARD domain.
Domain:
  • Contains 1 CARD domain.
genes like me logo Genes that share domains with QRICH1: view

No data available for Gene Families for QRICH1 Gene

Function for QRICH1 Gene

Gene Ontology (GO) - Molecular Function for QRICH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003674 molecular_function ND --
GO:0003677 DNA binding IBA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with QRICH1: view
genes like me logo Genes that share phenotypes with QRICH1: view

Animal Model Products

CRISPR Products

miRNA for QRICH1 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for QRICH1 Gene

Localization for QRICH1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for QRICH1 Gene COMPARTMENTS Subcellular localization image for QRICH1 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for QRICH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with QRICH1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for QRICH1 Gene

Pathways & Interactions for QRICH1 Gene

SuperPathways for QRICH1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for QRICH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription from RNA polymerase II promoter IEA --
GO:0007010 cytoskeleton organization IBA --
GO:0007275 multicellular organism development IBA --
GO:0008150 biological_process ND --
GO:0022604 regulation of cell morphogenesis IBA --
genes like me logo Genes that share ontologies with QRICH1: view

No data available for Pathways by source and SIGNOR curated interactions for QRICH1 Gene

Drugs & Compounds for QRICH1 Gene

No Compound Related Data Available

Transcripts for QRICH1 Gene

Unigene Clusters for QRICH1 Gene

Glutamine-rich 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for QRICH1 Gene

No ASD Table

Relevant External Links for QRICH1 Gene

GeneLoc Exon Structure for
QRICH1
ECgene alternative splicing isoforms for
QRICH1

Expression for QRICH1 Gene

mRNA expression in normal human tissues for QRICH1 Gene

Protein differential expression in normal tissues from HIPED for QRICH1 Gene

This gene is overexpressed in Lymph node (10.3), CD8 Tcells (9.4), and CD4 Tcells (7.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for QRICH1 Gene



Protein tissue co-expression partners for QRICH1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of QRICH1 Gene:

QRICH1

SOURCE GeneReport for Unigene cluster for QRICH1 Gene:

Hs.297389
genes like me logo Genes that share expression patterns with QRICH1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for QRICH1 Gene

Orthologs for QRICH1 Gene

This gene was present in the common ancestor of animals.

Orthologs for QRICH1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia QRICH1 34
  • 94.07 (n)
  • 98.71 (a)
QRICH1 35
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia QRICH1 34
  • 94.54 (n)
  • 99.23 (a)
QRICH1 35
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Qrich1 34
  • 92.1 (n)
  • 99.36 (a)
Qrich1 16
Qrich1 35
  • 99 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia QRICH1 34
  • 99.79 (n)
  • 100 (a)
QRICH1 35
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Qrich1 34
  • 91.79 (n)
  • 98.97 (a)
oppossum
(Monodelphis domestica)
Mammalia QRICH1 35
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia QRICH1 35
  • 93 (a)
OneToOne
chicken
(Gallus gallus)
Aves QRICH1 34
  • 83.29 (n)
  • 93.65 (a)
QRICH1 35
  • 94 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia QRICH1 35
  • 92 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100497567 34
  • 56.96 (n)
  • 52.86 (a)
Str.6077 34
African clawed frog
(Xenopus laevis)
Amphibia MGC68761 34
zebrafish
(Danio rerio)
Actinopterygii qrich1 34
  • 68.38 (n)
  • 70.67 (a)
qrich1 35
  • 68 (a)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7441 34
fruit fly
(Drosophila melanogaster)
Insecta woc 35
  • 11 (a)
OneToMany
Species where no ortholog for QRICH1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for QRICH1 Gene

ENSEMBL:
Gene Tree for QRICH1 (if available)
TreeFam:
Gene Tree for QRICH1 (if available)

Paralogs for QRICH1 Gene

Paralogs for QRICH1 Gene

genes like me logo Genes that share paralogs with QRICH1: view

Variants for QRICH1 Gene

Sequence variations from dbSNP and Humsavar for QRICH1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs7621347 -- 49,073,456(+) aatcg(C/T)ttgaa intron-variant
rs6777519 -- 49,073,635(+) TTTTG(A/T)GCCTT intron-variant
rs9833422 -- 49,067,964(+) aaaaa(A/T)ttgga intron-variant
rs7626445 -- 49,077,111(+) TTGCA(C/T)AAGAG intron-variant
rs9838638 -- 49,078,075(+) AGCAG(C/G)AGGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for QRICH1 Gene

Variant ID Type Subtype PubMed ID
esv2664917 CNV deletion 23128226
esv3400252 CNV insertion 20981092
esv3596118 CNV loss 21293372
nsv834686 CNV loss 17160897
nsv955614 CNV deletion 24416366

Variation tolerance for QRICH1 Gene

Residual Variation Intolerance Score: 5.32% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.23; 52.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for QRICH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
QRICH1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for QRICH1 Gene

Disorders for QRICH1 Gene

Relevant External Links for QRICH1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
QRICH1

No disorders were found for QRICH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for QRICH1 Gene

Publications for QRICH1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  4. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 65
  5. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 3 65

Products for QRICH1 Gene

Sources for QRICH1 Gene

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