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Aliases for QRICH1 Gene

Aliases for QRICH1 Gene

  • Glutamine Rich 1 2 3 5
  • Glutamine-Rich 1 2

External Ids for QRICH1 Gene

Previous GeneCards Identifiers for QRICH1 Gene

  • GC03M049043
  • GC03M049044
  • GC03M049046
  • GC03M049048
  • GC03M049051
  • GC03M049067
  • GC03M049074
  • GC03M049081
  • GC03M049086
  • GC03M049091
  • GC03M049097
  • GC03M049103

Summaries for QRICH1 Gene

GeneCards Summary for QRICH1 Gene

QRICH1 (Glutamine Rich 1) is a Protein Coding gene. An important paralog of this gene is ZMYM4.

Gene Wiki entry for QRICH1 Gene

Additional gene information for QRICH1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for QRICH1 Gene

Genomics for QRICH1 Gene

Regulatory Elements for QRICH1 Gene

Enhancers for QRICH1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H049338 1.9 FANTOM5 ENCODE dbSUPER 43.9 -251.7 -251687 14 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 AMT QRICH1 ATRIP ENSG00000235236 WDR6 RBM6 BSN-AS1 DALRD3 RBM5 IP6K2
GH03H049016 1.4 ENCODE dbSUPER 45.8 +74.1 74103 6 HDGF PKNOX1 ARNT ZFP64 ARID4B SIN3A FEZF1 ZNF2 ZBTB7B YY1 WDR6 ENSG00000235236 NICN1 FCF1P2 QRICH1 RBM6 ZNF589 ENSG00000223343 P4HTM AMT
GH03H049443 1.4 Ensembl ENCODE dbSUPER 32.4 -350.9 -350872 3 HDGF TBL1XR1 ARNT BATF THRB GTF3C2 ZNF207 FOS ATF7 ETV6 AMT QRICH1 IP6K2 USP19 TMEM115 QARS ATRIP SEMA3F-AS1 RHOA-IT1 WDR6
GH03H048742 1.7 FANTOM5 Ensembl ENCODE dbSUPER 24.5 +352.0 351995 1 YBX3 TBP HDGF PKNOX1 ATF1 TBL1XR1 ARNT NFRKB ZBTB40 TCF12 WDR6 AMT QRICH1 CCDC71 ATRIP PRKAR2A USP19 ZNF589 QARS NME6
GH03H049409 1.6 Ensembl ENCODE dbSUPER 24.5 -319.4 -319444 8 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 AMT QRICH1 CCDC71 ATRIP WDR6 SEMA3F-AS1 DALRD3 FAM212A RBM5 DAG1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around QRICH1 on UCSC Golden Path with GeneCards custom track

Promoters for QRICH1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000152182 663 2201 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for QRICH1 Gene

Chromosome:
3
Start:
49,029,707 bp from pter
End:
49,094,363 bp from pter
Size:
64,657 bases
Orientation:
Minus strand

Genomic View for QRICH1 Gene

Genes around QRICH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
QRICH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for QRICH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for QRICH1 Gene

Proteins for QRICH1 Gene

  • Protein details for QRICH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2TAL8-QRIC1_HUMAN
    Recommended name:
    Glutamine-rich protein 1
    Protein Accession:
    Q2TAL8
    Secondary Accessions:
    • Q4G0F7
    • Q7L621
    • Q8TEA5

    Protein attributes for QRICH1 Gene

    Size:
    776 amino acids
    Molecular mass:
    86436 Da
    Quaternary structure:
    No Data Available

neXtProt entry for QRICH1 Gene

Post-translational modifications for QRICH1 Gene

  • Ubiquitination at Lys28, Lys489, isoforms=495, and isoforms=712
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for QRICH1 Gene

Domains & Families for QRICH1 Gene

Gene Families for QRICH1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for QRICH1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for QRICH1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with QRICH1: view

No data available for UniProtKB/Swiss-Prot for QRICH1 Gene

Function for QRICH1 Gene

Phenotypes From GWAS Catalog for QRICH1 Gene

Gene Ontology (GO) - Molecular Function for QRICH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003674 molecular_function ND --
GO:0003677 DNA binding IBA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with QRICH1: view
genes like me logo Genes that share phenotypes with QRICH1: view

Animal Model Products

CRISPR Products

miRNA for QRICH1 Gene

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for QRICH1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for QRICH1 Gene

Localization for QRICH1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for QRICH1 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for QRICH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with QRICH1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for QRICH1 Gene

Pathways & Interactions for QRICH1 Gene

SuperPathways for QRICH1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for QRICH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription from RNA polymerase II promoter IEA --
GO:0007010 cytoskeleton organization IBA --
GO:0007275 multicellular organism development IBA --
GO:0008150 biological_process ND --
GO:0022604 regulation of cell morphogenesis IBA --
genes like me logo Genes that share ontologies with QRICH1: view

No data available for Pathways by source and SIGNOR curated interactions for QRICH1 Gene

Drugs & Compounds for QRICH1 Gene

No Compound Related Data Available

Transcripts for QRICH1 Gene

Unigene Clusters for QRICH1 Gene

Glutamine-rich 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for QRICH1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for QRICH1 Gene

No ASD Table

Relevant External Links for QRICH1 Gene

GeneLoc Exon Structure for
QRICH1
ECgene alternative splicing isoforms for
QRICH1

Expression for QRICH1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for QRICH1 Gene

Protein differential expression in normal tissues from HIPED for QRICH1 Gene

This gene is overexpressed in Lymph node (10.3), CD8 Tcells (9.4), and CD4 Tcells (7.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for QRICH1 Gene



Protein tissue co-expression partners for QRICH1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of QRICH1 Gene:

QRICH1

SOURCE GeneReport for Unigene cluster for QRICH1 Gene:

Hs.297389

Evidence on tissue expression from TISSUES for QRICH1 Gene

  • Nervous system(4.4)
  • Skin(4.3)
  • Liver(4.2)
  • Adrenal gland(2.1)
  • Bone marrow(2.1)
  • Kidney(2.1)
  • Thyroid gland(2.1)
genes like me logo Genes that share expression patterns with QRICH1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for QRICH1 Gene

Orthologs for QRICH1 Gene

This gene was present in the common ancestor of animals.

Orthologs for QRICH1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia QRICH1 33 34
  • 99.79 (n)
dog
(Canis familiaris)
Mammalia QRICH1 33 34
  • 94.54 (n)
cow
(Bos Taurus)
Mammalia QRICH1 33 34
  • 94.07 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia QRICH1 34
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Qrich1 33 16 34
  • 92.1 (n)
rat
(Rattus norvegicus)
Mammalia Qrich1 33
  • 91.79 (n)
oppossum
(Monodelphis domestica)
Mammalia QRICH1 34
  • 91 (a)
OneToOne
chicken
(Gallus gallus)
Aves QRICH1 33 34
  • 83.29 (n)
lizard
(Anolis carolinensis)
Reptilia QRICH1 34
  • 92 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100497567 33
  • 56.96 (n)
Str.6077 33
African clawed frog
(Xenopus laevis)
Amphibia MGC68761 33
zebrafish
(Danio rerio)
Actinopterygii qrich1 33 34
  • 68.38 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7441 33
fruit fly
(Drosophila melanogaster)
Insecta woc 34
  • 11 (a)
OneToMany
Species where no ortholog for QRICH1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for QRICH1 Gene

ENSEMBL:
Gene Tree for QRICH1 (if available)
TreeFam:
Gene Tree for QRICH1 (if available)

Paralogs for QRICH1 Gene

Paralogs for QRICH1 Gene

genes like me logo Genes that share paralogs with QRICH1: view

Variants for QRICH1 Gene

Sequence variations from dbSNP and Humsavar for QRICH1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000069161 -- 49,080,791(+) TGTTT(C/T)TGGAG intron-variant
rs1000107605 -- 49,083,732(+) CACTG(C/T)ACTCC intron-variant
rs1000126447 -- 49,088,057(+) CGCCA(G/T)TCTCC intron-variant
rs1000213530 -- 49,069,269(+) GGCTA(C/T)TTTTT intron-variant
rs1000225119 -- 49,038,856(+) ACCTC(A/G)TCTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for QRICH1 Gene

Variant ID Type Subtype PubMed ID
esv2664917 CNV deletion 23128226
esv3400252 CNV insertion 20981092
esv3596118 CNV loss 21293372
nsv834686 CNV loss 17160897
nsv955614 CNV deletion 24416366

Variation tolerance for QRICH1 Gene

Residual Variation Intolerance Score: 5.32% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.23; 52.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for QRICH1 Gene

Human Gene Mutation Database (HGMD)
QRICH1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
QRICH1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for QRICH1 Gene

Disorders for QRICH1 Gene

Relevant External Links for QRICH1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
QRICH1

No disorders were found for QRICH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for QRICH1 Gene

Publications for QRICH1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 60
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60

Products for QRICH1 Gene

Sources for QRICH1 Gene

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