QARS Gene
protein-coding GIFtS: 62
GCID: GC03M049108
|
|
glutaminyl-tRNA synthetase
| |
Aliases
for QARS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Glutaminyl-TRNA Synthetase1 2 3 | | Glutamine--TRNA Ligase2 | | EC 6.1.1.183 8 | | Glutamine-TRNA Synthetase2 | | GLNRS2 5 | | GlnRS3 | | PRO21952 | | EC 6.1.18 |
Export aliases for QARS gene to outside databasesPrevious GC identifers: GC03P046968 GC03P048503 GC03M048987 GC03M049092 |
Summaries
for QARS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for QARS:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their centralrole in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to beamong the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine(gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present ineukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, inwhich Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongsto the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.(provided by RefSeq, Jan 2013)
Gene Wiki entry for QARS
|
Genomic Views
for QARS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the QARS gene promoter:
ATF-2 MyoD Olf-1 LUN-1 NF-E2 p45 PPAR-alpha Max CRE-BP1 NF-E2 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for QARS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QARS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.31 Ensembl cytogenetic band: 3p21.31 HGNC cytogenetic band: 3p21.31QARS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M049108: view genomic region
(about GC identifiers)
Start:
|
49,133,365 bp from pter |
End:
|
49,142,553 bp from pter |
Size:
|
9,189 bases |
Orientation:
|
minus strand |
|
Proteins
for QARS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SYQ_HUMAN, P47897 (See
protein sequence)Recommended Name: Glutamine--tRNA ligase Size: 775 amino acids; 87799 Da
Subunit: Part of a multisubunit complex that groups tRNA ligases for Arg, Asp, Glu, Gln, Ile, Leu, Lys, Met and Pro
Subcellular location: CytoplasmExplore the universe of human proteins at neXtProt for QARS: NX_P47897
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P47897
4/8 DME Specific Peptides for QARS (P47897) (see all 8)
QARS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001259002.1 NP_005042.1
ENSEMBL proteins: ENSP00000396326 ENSP00000307567 ENSP00000389823 ENSP00000390015 ENSP00000392850 ENSP00000415247 ENSP00000414686 ENSP00000399119 Reactome Protein details: P47897
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
QARS for ontologies About GeneDecksing
QARS Antibody Products:
Assay Products for QARS: |
Protein
Domains /
Families
for QARS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
QARS for domains About GeneDecksing
5/11 InterPro domains/families (see all 11):Graphical View of Domain Structure for InterPro Entry P47897ProtoNet protein and cluster: P47897 2 Blocks protein families: IPB000924 Glutamyl-tRNA synthetase signature IPB007639 Glutaminyl-tRNA synthetase
UniProtKB/Swiss-Prot: SYQ_HUMAN, P47897Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family |
Function
for QARS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SYQ_HUMAN, P47897Catalytic activity: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln) Genatlas biochemistry entry for QARS:glutamine-tRNA synthetase
Enzyme Numbers (IUBMB): EC 6.1.1.181 2 EC 6.1.12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QARS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QARS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: QARS (NM_005051) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for QARS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat QARS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QARS |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004812 | aminoacyl-tRNA ligase activity |
-- | -- | | GO:0004819 | glutamine-tRNA ligase activity |
TAS | -- | | GO:0005524 | ATP binding |
IEA | -- |
QARS for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for QARS:
|
Pathways & Interactions
for QARS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | tRNA Aminoacylation | | | 2 | Glutamic acid signaling | | | 3 | Generic Transcription Pathway | | | 4 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for QARS
4 
Reactome Pathways for QARS
2 
Kegg Pathways (Kegg details for QARS):
QARS for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for QARS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/85 Interacting proteins for QARS (P478971, 2, 3 ENSP000003075674) via UniProtKB, MINT, STRING, and/or I2D (see all 85)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006418 | tRNA aminoacylation for protein translation |
TAS | -- | | GO:0006425 | glutaminyl-tRNA aminoacylation |
IEA | -- | | GO:0010467 | gene expression |
TAS | -- |
QARS for ontologies About GeneDecksing
|
Drugs & Compounds
for QARS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
QARS for compounds About GeneDecksing
 Browse Tocris compounds for QARS
5 HMDB Compounds for QARS About this table
1 DrugBank Compound for QARS About this table
8 Novoseek chemical compound relationships for QARS gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| trna(gln) |
96.4 |
11 |
10860750 (2), 9372179 (2), 8078941 (1), 14729703 (1) (see all 5) |
| aminoacyl-trna |
87.4 |
1 |
8643392 (1) |
| trna |
84.2 |
43 |
8643392 (2), 9698378 (2), 10486006 (2), 9562563 (2) (see all 12) |
| acrylodan |
80.4 |
1 |
15966719 (1) |
| anticodon |
65.9 |
2 |
8199240 (1), 9372179 (1) |
| glutamine |
60.1 |
5 |
9698378 (1), 8360919 (1), 12737824 (1), 9562563 (1) |
| atp |
35.4 |
7 |
7659511 (1), 17444518 (1), 12737824 (1), 9372179 (1) (see all 5) |
| glutamate |
32.1 |
6 |
15845537 (2), 9698378 (1), 17048947 (1) |
Search CenterWatch for drugs/clinical trials and news about QARS / SYQ
|
Transcripts
for QARS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for QARS gene (2 alternative transcripts): NM_001272073.1 NM_005051.2 Unigene Cluster for QARS: Glutaminyl-tRNA synthetase Hs.79322 [show with all ESTs]Unigene Representative Sequence: AK22251018/26 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 26): ENST00000482248(uc011bcc.2) ENST00000453392 ENST00000306125(uc003cvx.3 uc003cvy.3 uc011bce.2)
ENST00000475599 ENST00000487495 ENST00000497635 ENST00000430182 ENST00000494984
ENST00000414533 ENST00000464962(uc011bcd.2) ENST00000459870 ENST00000470113
ENST00000466179 ENST00000482468 ENST00000478561 ENST00000494838 ENST00000470225
ENST00000494767
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QARS (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QARS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: QARS (NM_005051) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for QARS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat QARS |
Additional cDNA sequence: AF130067.1 AK056815.1 AK222510.1 AK290523.1 AK293260.1 AK297987.1 AK300220.1 AK301559.1 AK302867.1 BC000394.2 BC001567.1 BC001772.1 BC016634.1 BC029739.1 JN104585.1 X76013.1 24/55 DOTS entries (see all 55): DT.452919 DT.95100991 DT.100885556 DT.100885542 DT.100885572 DT.120923462 DT.95328884 DT.95313709 DT.100832404 DT.120923461 DT.100885565 DT.120923527 DT.100885546 DT.120923446 DT.120923569 DT.120923574 DT.120923477 DT.120923596 DT.100650187 DT.95100993 DT.100885550 DT.120923544 DT.100885537 DT.100885559 24/1126 AceView cDNA sequences (see all 1126): X76013 AL582998 AU121457 BM760238 AA604975 AI299471 BQ636289 BG179717 BE251947 BM761045 BU160141 BM480039 BP379989 BM670024 CB152024 BM757040 BG324028 BQ420886 BM671657 BQ651014 AU076944 BQ058936 BM834661 BM831552
GeneLoc Exon Structure
5/25 Alternative Splicing Database (ASD) splice patterns (SP) for QARS (see all 25) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | · | 3f | · | 3g | · | 3h | · | 3i | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | - | | - | | - | | - | | | | | | | | | | - | | - | | - | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | - | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | - | | | | |
| SP4: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | - | | - | | - | |
| ExUns: | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | · | 15c | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ |
|---|
|
| SP1: | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 27a | · | 27b | ^ | 28a | · | 28b | ^ | 29 |
|---|
|
| SP1: | - | | | | | | | | | | |
| SP2: | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for QARS
|
Expression
for QARS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| QARS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCAATAAAGA
About this image
See QARS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for QARS
SOURCE GeneReport for Unigene cluster: Hs.79322
SABiosciences Custom PCR Arrays for QARS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for QARS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat QARS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat QARS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QARS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QARS |
Orthologs
for QARS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for QARS gene from 11/41 species (see all 41) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Qars1 , 5 |
glutaminyl-tRNA synthetase1, 5 |
85.68(n)1
89.94(a)1 |
|
9 (59.44 cM)5
975411 NM_133794.21 NP_598555.21
1085080055 |
chicken
(Gallus gallus) |
Aves |
QARS1 |
glutaminyl-tRNA synthetase |
74.86(n)
78.54(a) |
|
416057 NM_001012782.1 NP_001012800.1 |
lizard
(Anolis carolinensis) |
Reptilia |
QARS6 |
-- |
77(a) |
1 ↔ 1 |
2(187979992-188014666) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC691282 |
hypothetical protein MGC69128 |
75.34(n) |
|
BC057752.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc563952 |
similar to glutaminyl-tRNA synthetase |
77.38(n) |
|
394188 BC049420.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Aats-gln1 , 3 |
glutaminyl-tRNA aminoacylation ATP binding3
Glutaminyl-tRNA synthetase1 |
57(a)3
60.95(n)1
58.31(a)1 |
|
96C83
457861 NM_080102.41 NP_524841.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
qrs-53
qars-11 |
tRNA synthetases class I (E and Q)3
Protein QARS-11 |
56(a)3
57.23(n)1
57.67(a)1 |
|
IV(15008792-15013338)3
1784151 NM_070411.51 NP_502812.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
GLN4(YOR168W)4
GLN41 |
Glutamine tRNA synthetase, monomeric class I tRNA synthetase more4
Gln4p1 |
47.28(n)1
42.25(a)1 |
|
15(649303-651732)4
8543391, 4 NP_014811.31 NP_014811.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
OVA91 |
putative tRNA-glutamine synthetase |
51.12(n)
43.5(a) |
|
839120 NM_001198165.1 NP_001185094.1 |
rice
(Oryza sativa) |
Liliopsida |
AK065125.12 |
-- |
70.41(n) |
|
AK065125.1 |
ENSEMBL Gene Tree for QARS (if available)
TreeFam Gene Tree for QARS (if available) |
Paralogs
for QARS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for QARS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for QARS (49133365 - 49142553 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for QARS: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing QARS |
|
Disorders
/ Diseases
for QARS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
QARS for disorders About GeneDecksing
OMIM gene information: 603727
OMIM disorders: --
2  diseases for QARS: About MalaCardsappendicitis malaria
Export disorders for QARS gene to outside databases
|
Publications
for QARS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for QARS gene, integrated from 9 sources (see all 67):
(articles sorted by number of sources associating them with QARS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer. (PubMed id 8078941)1, 2, 3, 9 Lamour V....Mirande M. (1994)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Characterization of the human laminin beta2 chain locus (LAMB2): linkage to a gene containing a nonprocessed, transcribed LAMB2-like pseudogene (LAMB2L) and to the gene encoding glutaminyl tRNA synthetase (QARS). (PubMed id 10393422)1, 3 Durkin M.E....Wewer U.M. (1999)
- Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. (PubMed id 9878398)1, 9 Quevillon S.... Mirande M. (1999)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. (PubMed id 22223895)1 Bienvenut W.V.... Giglione C. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
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External Searches for QARS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing QARS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing QARS gene
(According to HUGE)
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Specialized Databases showing QARS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for QARS | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for QARS gene:
Search GeneIP for patents involving QARS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for QARS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for QARS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for QARS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for QARS | | | OriGene Protein Over-expression Lysate for QARS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for QARS | | OriGene 3'-UTR Clone for QARS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for QARS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for QARS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for QARS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for QARS | | OriGene Custom Protein Services for QARS | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat QARS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing QARS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat QARS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat QARS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat QARS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat QARS |
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| | | | Search Tocris compounds for QARS |
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 | | | QARS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for QARS |
|  |  |  | | | | ThermoFisher Antibody for QARS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat QARS |
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