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PYGB Gene

protein-coding GIFtS: 60

GC20P025176

phosphorylase, glycogen; brain
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
EC 2.4.1.1 ^³
MGC9213 ^²
OTTHUMP00000030488 ^²

Descriptions
brain glycogen phosphorylase ^²
glycogen phosphorylase B ^²
phosphorylase, glycogen; brain ^²

External Ids
HGNC: 9723¹
Entrez Gene: 5834²
UniProtKB: P11216³
Ensembl: ENSG00000100994⁷

Search outside databases for aliases for PYGB gene

Previous GC identifers: GC20P025216 GC20P025223

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for PYGB:

The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The

encoded protein forms homodimers which can associate into homotetramers, the enzymatically active

form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and

negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the

rate-determining step in glycogen degradation. [provided by RefSeq]

UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216

Function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from

different sources differ in their regulatory mechanisms and in their natural substrates. However,

all known phosphorylases share catalytic and structural properties

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the PYGB gene

Entrez Gene cytogenetic band: 20p11.2-p11.1 Ensembl cytogenetic band: 20p11.21 HGNC chromosome: 20

PYGB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P025176: (about GC identifiers)

Start:	25,176,706 bp from pter
End:	25,226,648 bp from pter
Size:	49,943 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000020.9 NT_011387.8

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216 (See protein sequence)

Recommended Name: Glycogen phosphorylase, brain form

Size: 843 amino acids; 96696 Da

Cofactor: Pyridoxal phosphate

Subunit: Homodimer. Dimers associate into a tetramer to form the enzymatically active phosphorylase

Secondary accessions: Q96AK1 Q9NPX8

Post-translational modifications:

Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002853.2

ENSEMBL proteins:

ENSP00000216962 ENSP00000365780

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GPBB)
	Human Recombinant Proteins from Abnova (PYGB)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IDA	10638593

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Antibodies for PYGB:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (GPBB), each with their Abpromise^SM
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	Novus Biologicals Antibodies for PYGB

Assays for PYGB:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P11216

ProtoNet protein and cluster: P11216

1 Blocks protein family: IPB000811 Glycosyl transferase

UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216

Similarity: Belongs to the glycogen phosphorylase family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (PYGB)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002862

Applied Biosystems Silencer® siRNAs for PYGB

Sigma-Aldrich siRNA and siRNA Panels for PYGB

Sigma-Aldrich shRNA for PYGB

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for PYGB
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002862
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002862
untagged cDNA clone in CMV expression vector: NM_002862

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002862

UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216

Function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from

different sources differ in their regulatory mechanisms and in their natural substrates. However,

all known phosphorylases share catalytic and structural properties

Catalytic activity: (1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) +

alpha-D-glucose 1-phosphate

Enzyme regulation: Activity of phosphorylase is controlled both by allosteric means (through the

non-covalent binding of metabolites) and by covalent modification. Thus AMP allosterically

activates, whereas ATP, ADP, and glucose-6-phosphate allosterically inhibit, phosphorylase B

Enzyme Number (IUBMB): EC 2.4.1.1

Genatlas biochemistry entry for PYGB:

phosphorylase,glycogen catabolism,brain

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008184	glycogen phosphorylase activity	NAS	3346228
GO:0016757	transferase activity, transferring glycosyl groups	IEA	--
GO:0030170	pyridoxal phosphate binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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2 Sigma-Aldrich "Your Favorite Gene" Pathways for PYGB (Your Favorite Gene powered by Ingenuity)

Starch and Sucrose Metabolism
&alpha

GeneDecks PYGB for the pathways selected above

About GeneDecksing

5/30 Interacting proteins for PYGB (ENSP00000216962³) via UniProtKB, MINT, and/or STRING (see all 30 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PHKA2	ENSP00000369274³	STRING (score=.956)
UGP2	ENSP00000338703³	STRING (score=.954)
AGL	ENSP00000309020³	STRING (score=.953)
GBE1	ENSP00000264326³	STRING (score=.943)
GYS1	ENSP00000317904³	STRING (score=.938)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	IEA	--
GO:0005980	glycogen catabolic process	NAS	3346228

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for PYGB:

Inhibitor

Browse Tocris compounds for PYGB
10/13 Novoseek chemical compound relationships for PYGB gene (see all 13 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
1-glcnac	94.32	2	16616506 (1)
heptulose-2-p	92.48	1	7987213 (1)
glycogen	88.05	101	7744850 (5), 1459992 (4), 9583890 (3), 9792273 (2) (see all 69)
galactose-1-phosphate	78.39	3	15299833 (1), 8948464 (1), 7987213 (1)
pyranose	59.00	1	9568898 (1)
thermolysin	58.66	3	11784144 (1), 15481990 (1), 12213058 (1)
hydrogen	40.46	1	9711498 (1)
glucose	33.60	7	15299833 (1), 11886794 (1), 8057302 (1), 8180201 (1) (see all 6)
glucose 6-phosphate	32.71	1	8331662 (1)
adp	17.17	1	8250871 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (PYGB)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002862

Sigma-Aldrich siRNA and siRNA Panels for PYGB

Sigma-Aldrich shRNA for PYGB

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002862

REFSEQ mRNAs for PYGB gene:

NM_002862.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002862

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002862
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002862
                                 untagged cDNA clone in CMV expression vector: NM_002862

Additional cDNA sequence:

AB209080.1 AF432222.1 AK299697.1 AK309036.1 BC017045.2 BC030795.2 BC113105.1 BC113106.1

CR609882.1 J03544.1 U47025.1 Z36853.1

24/28 DOTS entries (see all 28 ):

DT.100815386 DT.450117 DT.100815395 DT.100747245 DT.100815382 DT.120832388 DT.120832288 DT.100810220

DT.100815393 DT.91744532 DT.120832377 DT.450116 DT.91763628 DT.100815389 DT.91936184 DT.92345604

DT.100697009 DT.100699697 DT.100747248 DT.100815397 DT.120832340 DT.91922003 DT.95105546 DT.95278098

24/555 AceView cDNA sequences (see all 555 ):

BG033441 BM980763 BC017045 AF432222 BQ084148 CD518408 NM_002862 BQ433140

AI868699 BQ955038 H72006 H40900 BM700321 CD743231 CA416506 BQ955182

BU182767 BQ876761 BQ958442 BM784716 BU156170 BC030795 BE869606 AI420362

highest scoring ESTs for PYGB:

U47025 AA209502 AA209516 AA300643 AA306840 AA315841 AA326607 AA336995 AA349658 AA418137

Unigene Cluster for PYGB:

Phosphorylase, glycogen; brain

Hs.368157 [show with all ESTs]

Unigene Representative Sequence: BC017045

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000216962 ENST00000376595

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

PYGB expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for PYGB

¹ / ² / ³

4 probe-sets matching PYGB gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
36667_at²^{, 3}	U95-A	1	0.94	1.00	0.99	1.00	U47025	1.00	1.00	1.00	1
59669_at²^{, 3}	U95-C	1	0.81	1.00	0.99	1.00	AI924969	0.40	1.00	0.76	1
201481_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002862	0.60	1.00	0.82	1
201481_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTGGATCTGG

SOURCE GeneReport for Unigene cluster: Hs.368157
Expression variation in blood from EXPOLDB for PYGB

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for PYGB gene from 5/19 species (see all 19 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	PYGB¹	--	phosphorylase, glycogen; brain	89.86(n) 94.81(a)	477003 XM_534201.2 XP_534201.2
chimpanzee (Pan troglodytes)	PYGB¹	--	phosphorylase, glycogen; brain	99.37(n) 100(a)	469908 XM_525293.2 XP_525293.2
cow (Bos taurus)	PYGB¹	--	phosphorylase, glycogen; brain	89.68(n) 93.59(a)	505560 NM_001035270.1 NP_001030347.1
rat (Rattus norvegicus)	Pygb¹	--	phosphorylase, glycogen; brain	88.53(n) 95.37(a)	25739 XM_342542.3 XP_342543.1
mouse (Mus musculus)	Pygb^{1, 5}	2 (84.00 cM)⁵	brain glycogen phosphorylase^{1, 5}	88.61(n)¹ 95.61(a)¹	110078¹ NM_153781.1¹ NP_722476.1¹ AI846739⁵ AK028744⁵ (see all 30)

About this table Species with no ortholog for PYGB

ENSEMBL Gene Tree for PYGB

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for PYGB gene

PYGL² PYGM²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/427 NCBI SNPs in PYGB are shown (see all 427 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 106)

AB	SNP ID	Valid	Chr 20 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2227891^1,2	A,C,F,H	25210769(+)	`TGGCCG/AATACC`	1	N/D	mis¹ ese³		10		MN EA NA EU WA	2164
	rs2228976^1,2	C,F,H	25207006(+)	`TGGCCG/TCCACG`	1	A/S	mis¹ ese³		13		MN NA EU EA WA	1092
	rs6115125^1,2	H	25208954(+)	`GCTGCC/TTGAGG`	1	P/L	mis¹ ese³		4		EU EA WA	418
--	rs6132822^1,2	A	25176695(+)	`TCCCGC/TCCGCA`	1	--	ng5¹		0	--	--	--	--
	rs6037077^1,2	H	25203283(+)	`GCGGCC/TTGAGT`	1	P/L	mis¹ ese³		4		EU EA WA	420
	rs6050483^1,2	H	25175084(+)	`ctcacC/Tttctc`	1	--	ng5¹		4		EU EA WA	402
	rs2227892^1,2	A,C,F,H	25212814(+)	`TTCGAC/TGTGCA`	1	D/D	syn¹ ese³		9		MN EU EA WA NA	694
	rs2227890^1,2	A,C,F,H	25208931(+)	`TGTGCG/ATACAC`	1	A/A	syn¹ ese³		9		MN EU EA WA NA	668
	rs2228977^1,2	C,F,H	25211895(+)	`AGGGAC/TGTGGC`	1	D/D	syn¹ ese³		6		MN NA EU EA WA	536
--	rs2227894^1,2	F	25203338(+)	`GACGGC/TGTGAA`	1	G/G	syn¹		8		MN EU EA WA NA	604

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HapMap Linkage Disequilibrium images for PYGB (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 138550

4 Novoseek disease relationships for PYGB gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
gastric carcinoma	30.56	1	10638593 (1)
cancer	5.32	1	9583890 (1)
myocardial infarction	0.00	1	8096924 (1)
carcinoma	0.00	2	9792273 (1), 9583890 (1)

About this table

Human Genome Epidemiology Navigator: PYGB (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/81 PubMed articles for PYGB gene (see all 81 ):

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)^{3, 4} Gevaert K.... Vandekerckhove J. (2003)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{3, 4} Deloukas P....Rogers J. (2001)
Human brain glycogen phosphorylase: characterization of fetal cDNA and genomic sequences. (PubMed id 2615594)^{3, 4} Gelinas R.P.... Gorin F.A. (1989)
Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes. (PubMed id 3346228)^{3, 4} Newgard C.B....Fletterick R.J. (1988)
Expression of brain-type glycogen phosphorylase is a potentially novel early biomarker in the carcinogenesis of human colorectal carcinomas. (PubMed id 10638593)^{1, 3} Tashima S....Ogawa M. (2000)
Nuclear localization of brain-type glycogen phosphorylase in some gastrointestinal carcinoma. (PubMed id 9792273)^{1, 3} Uno K....Ogawa M. (1998)
Clinicopathological significance of BGP expression in non-small-cell lung carcinoma: relationship with histological type, microvessel density and patients' survival. (PubMed id 17393985)^{1, 3} Lee M.K....Sol M.Y. (2006)
Primate rod and cone photoreceptors may differ in glucose accessibility. (PubMed id 7775103)^{1, 3} Nihira M....Burns M.S. (1995)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 5834	HGNC: 9723	AceView: PYGB	Ensembl:ENSG00000100994	euGenes: HUgn5834
ECgene: PYGB	H-InvDB: PYGB

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for PYGB
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for PYGB:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for PYGB-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for PYGB		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for PYGB		Small molecules for PYGB
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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PYGB Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for PYGB

Summaries
for PYGB

Genomic Location
for PYGB

Proteins
for PYGB

Protein Domains/
Families
for PYGB

Gene Function
for PYGB

Pathways & Interactions
for PYGB

Drugs & Compounds
for PYGB

Transcripts
for PYGB

Expression
for PYGB

Orthologs
for PYGB

Paralogs
for PYGB

SNPs/Variants
for PYGB

Disorders & Mutations
for PYGB

Medical News
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Publications
for PYGB

Search for PYGB

Genome Databases showing PYGB

Other Databases showing PYGB

Specialized Databases showing PYGB

Licensable Technologies
for PYGB

Services
for PYGB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

PYGB Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor PYGB

Summariesfor PYGB

Genomic Locationfor PYGB

Proteinsfor PYGB

Protein Domains/Familiesfor PYGB

Gene Functionfor PYGB

Pathways & Interactionsfor PYGB

Drugs & Compoundsfor PYGB

Transcriptsfor PYGB

Expression for PYGB

Orthologsfor PYGB

Paralogsfor PYGB

SNPs/Variantsfor PYGB

Disorders & Mutationsfor PYGB

Medical Newsfor PYGB

Publicationsfor PYGB

Search for PYGB

Genome Databases showing PYGB

Other Databases showing PYGB

Specialized Databases showing PYGB

Licensable Technologiesfor PYGB

Servicesfor PYGB

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for PYGB

Summaries
for PYGB

Genomic Location
for PYGB

Proteins
for PYGB

Protein Domains/
Families
for PYGB

Gene Function
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Pathways & Interactions
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