PYGB Gene
protein-coding GIFtS: 61
GCID: GC20P025228
|
|
phosphorylase, glycogen; brain
| |
Aliases
for PYGB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Phosphorylase, Glycogen; Brain1 2 | | EC 2.4.1.13 8 | | GPBB2 | | Glycogen Phosphorylase B2 | | Glycogen Phosphorylase, Brain Form2 |
Export aliases for PYGB gene to outside databasesPrevious GC identifers: GC20P025216 GC20P025223 GC20P025176 GC20P025186 |
Summaries
for PYGB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PYGB:
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded proteinforms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. Theactivity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate.This enzyme catalyzes the rate-determining step in glycogen degradation. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216Function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sourcesdiffer in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases sharecatalytic and structural properties
|
Genomic Views
for PYGB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PYGB gene promoter:
CREB POU2F1 POU2F1a NRSF form 1 deltaCREB SEF-1 (1) NRSF form 2 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PYGB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PYGB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p11.2-p11.1 Ensembl cytogenetic band: 20p11.21 HGNC chromosome: 20PYGB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P025228: view genomic region
(about GC identifiers)
Start:
|
25,228,705 bp from pter |
End:
|
25,278,650 bp from pter |
Size:
|
49,946 bases |
Orientation:
|
plus strand |
|
Proteins
for PYGB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216 (See
protein sequence)Recommended Name: Glycogen phosphorylase, brain form Size: 843 amino acids; 96696 Da
Cofactor: Pyridoxal phosphate
Subunit: Homodimer. Dimers associate into a tetramer to form the enzymatically active phosphorylase A
Secondary accessions: Q96AK1 Q9NPX8Explore the universe of human proteins at neXtProt for PYGB: NX_P11216
Post-translational modifications:
Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P11216
4/43 DME Specific Peptides for PYGB (P11216) (see all 43)
PYGB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002853.2
ENSEMBL proteins: ENSP00000216962 ENSP00000395451 Reactome Protein details: P11216
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
PYGB for ontologies About GeneDecksing
PYGB Antibody Products:
Assay Products for PYGB: |
Protein
Domains /
Families
for PYGB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PYGB for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P11216ProtoNet protein and cluster: P11216 1 Blocks protein family: IPB000811 Glycosyl transferase
UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216Similarity: Belongs to the glycogen phosphorylase family |
Function
for PYGB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PYGB_HUMAN, P11216Function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sourcesdiffer in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases sharecatalytic and structural propertiesCatalytic activity: (1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphateEnzyme regulation: Activity of phosphorylase is controlled both by allosteric means (through the non-covalent bindingof metabolites) and by covalent modification. Thus AMP allosterically activates, whereas ATP, ADP, andglucose-6-phosphate allosterically inhibit, phosphorylase B Genatlas biochemistry entry for PYGB:phosphorylase,glycogen catabolism,brain
Enzyme Number (IUBMB): EC 2.4.1.11 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PYGB (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PYGB
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PYGB (NM_002862) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PYGB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PYGB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PYGB |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
PYGB for ontologies About GeneDecksing
|
Pathways & Interactions
for PYGB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Galactose metabolism | | | 2 | Activation of cAMP-Dependent PKA | | | 3 | Glycogen breakdown (glycogenolysis) | | | 4 | Glucose metabolism | | | 5 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for PYGB
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for PYGB
2  GeneGo (Thomson Reuters) Pathways for PYGB
1  BioSystems Pathway for PYGB
4 
Reactome Pathways for PYGB
2 
Kegg Pathways (Kegg details for PYGB):
PYGB for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PYGB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/47 Interacting proteins for PYGB (P112163 ENSP000002169624) via UniProtKB, MINT, STRING, and/or I2D (see all 47)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005975 | carbohydrate metabolic process |
TAS | -- | | GO:0005977 | glycogen metabolic process |
-- | -- | | GO:0005980 | glycogen catabolic process |
TAS | -- | | GO:0006006 | glucose metabolic process |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- |
PYGB for ontologies About GeneDecksing
|
Drugs & Compounds
for PYGB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PYGB for compounds About GeneDecksing
 Browse Tocris compounds for PYGB
9 HMDB Compounds for PYGB About this table
1 DrugBank Compound for PYGB About this table
10/19 Novoseek chemical compound relationships for PYGB gene (see all 19) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 1-glcnac |
94.2 |
2 |
16616506 (1) |
| heptulose-2-p |
92.3 |
1 |
7987213 (1) |
| glycogen |
87.9 |
104 |
7744850 (5), 1459992 (4), 9583890 (3), 9792273 (2) (see all 72) |
| galactose-1-phosphate |
77.5 |
3 |
15299833 (1), 8948464 (1), 7987213 (1) |
| pyridoxal 5-phosphate |
68.7 |
5 |
8457673 (1), 8503849 (1), 8025540 (1) |
| thermolysin |
64.4 |
4 |
11784144 (1), 15481990 (1), 12213058 (1), 19994892 (1) |
| pyranose |
57.6 |
1 |
9568898 (1) |
| hydrogen |
42.6 |
1 |
9711498 (1) |
| glucose |
35.4 |
7 |
15299833 (1), 11886794 (1), 8057302 (1), 8180201 (1) (see all 6) |
| glucose 6-phosphate |
31.4 |
1 |
8331662 (1) |
Search CenterWatch for drugs/clinical trials and news about PYGB
|
Transcripts
for PYGB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PYGB gene: NM_002862.3 Unigene Cluster for PYGB: Phosphorylase, glycogen; brain Hs.368157 [show with all ESTs]Unigene Representative Sequence: BC0170453 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000216962(uc002wup.3) ENST00000428458 ENST00000471359
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PYGB (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PYGB
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PYGB (NM_002862) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PYGB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PYGB |
Additional cDNA sequence: AB209080.1 AF432222.1 AK299697.1 AK309036.1 BC017045.2 BC030795.2 BC113105.1 BC113106.1 BC128043.1 J03544.1 U47025.1 Z36853.1 24/28 DOTS entries (see all 28): DT.100815386 DT.450117 DT.100815395 DT.100747245 DT.120832388 DT.100815382 DT.120832288 DT.100810220 DT.120832377 DT.100815393 DT.91744532 DT.91763628 DT.100815389 DT.450116 DT.91936184 DT.92345604 DT.95102231 DT.100697009 DT.100699697 DT.100747248 DT.100815397 DT.120832340 DT.91922003 DT.95105546 24/555 AceView cDNA sequences (see all 555): CD743231 BQ054119 BQ955182 BQ003847 BX487446 BM705882 BM790178 BM833334 BQ683320 BQ640368 BG033441 CK904406 BG763492 H40900 BM670513 BM021383 AI868699 AI571841 BM669629 BU158353 BM782289 AI420362 CA416506 NM_002862
GeneLoc Exon Structure
|
Expression
for PYGB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PYGB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGGATCTGG
About this image
See PYGB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PYGB
SOURCE GeneReport for Unigene cluster: Hs.368157
SABiosciences Custom PCR Arrays for PYGB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PYGB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PYGB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PYGB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PYGB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PYGB |
Orthologs
for PYGB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for PYGB gene from 11/35 species (see all 35) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Pygb1 , 5 |
brain glycogen phosphorylase1, 5 |
88.61(n)1
95.61(a)1 |
|
2 (74.74 cM)5
1100781 NM_153781.11 NP_722476.11
1507867355 |
chicken
(Gallus gallus) |
Aves |
PYGB1 |
phosphorylase, glycogen; brain |
82.68(n)
90.98(a) |
|
421248 NM_001031034.1 NP_001026205.1 |
lizard
(Anolis carolinensis) |
Reptilia |
PYGB6PYGL6 |
-- |
90(a)69(a) |
1 ↔ 1possible ortholog |
1(254332354-254356754) GL343850.1(12752-85445) |
African clawed frog
(Xenopus laevis) |
Amphibia |
pygm-prov2 |
phosphorylase, glycogen; brain |
80.49(n) |
|
BC047245.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BC055233.12 |
-- |
78.27(n) |
|
BC055233.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
GlyP3 |
carbohydrate metabolism phosphorylase |
72(a) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
T22F3.36 |
Phosphorylase |
65(a) |
1 → many |
V(3579044-3585042) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
GPH11 |
Gph1p |
54.68(n)
52.35(a) |
|
856289 NP_015486.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATPHS26AT3G293206 |
glycosyl transferase, family 35 protein |
45(a)39(a) |
possible orthologpossible ortholog |
3(17301394-17306446) 3(11252807-11257814) |
rice
(Oryza sativa) |
Liliopsida |
---- |
alpha-glucan phosphorylast isozyme, putative, expr...alpha-glucan phosphorylast isozyme, putative, expr... |
45(a)37(a) |
possible orthologpossible ortholog |
1(36669178-36675435) 3(31325281-31332048) |
ENSEMBL Gene Tree for PYGB (if available)
TreeFam Gene Tree for PYGB (if available) |
Paralogs
for PYGB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PYGB gene
- PYGL2 PYGM2
2 SIMAP similar genes for PYGB using alignment to 2 protein entries: PYGB_HUMAN (see all proteins):PYGM PYGL
PYGB for paralogs About GeneDecksing
|
Genomic Variants
for PYGB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PYGB (25228705 - 25278650 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PYGB: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PYGB |
|
Disorders
/ Diseases
for PYGB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PYGB for disorders About GeneDecksing
OMIM gene information: 138550
OMIM disorders: --
15  diseases for PYGB: About MalaCardsfructose-1,6-bisphosphatase deficiency glycogen storage disease v glycogen storage disease non-small cell lung carcinoma
myocardial infarction hyperinsulinism lung carcinoma hyperglycemia
carcinoma cardiomyopathy astrocytoma breast cancer
pneumonia tuberculosis mycobacterium tuberculosis
4 Novoseek disease relationships for PYGB gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gastric carcinoma |
29.1 |
1 |
10638593 (1) |
| cancer |
4.89 |
1 |
9583890 (1) |
| myocardial infarction |
0 |
1 |
8096924 (1) |
| carcinoma |
0 |
2 |
9792273 (1), 9583890 (1) |
Human Genome Epidemiology (HuGE) Navigator: PYGB (5 documents)
Export disorders for PYGB gene to outside databases
|
Publications
for PYGB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PYGB gene, integrated from 9 sources (see all 105):
(articles sorted by number of sources associating them with PYGB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- Human brain glycogen phosphorylase: characterization of fetal cDNA and genomic sequences. (PubMed id 2615594)1, 2 Gelinas R.P.... Gorin F.A. (1989)
- Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes. (PubMed id 3346228)1, 2 Newgard C.B....Fletterick R.J. (1988)
- Expression of brain-type glycogen phosphorylase is a potentially novel early biomarker in the carcinogenesis of human colorectal carcinomas. (PubMed id 10638593)1, 9 Tashima S....Ogawa M. (2000)
- Nuclear localization of brain-type glycogen phosphorylase in some gastrointestinal carcinoma. (PubMed id 9792273)1, 9 Uno K....Ogawa M. (1998)
- Clinicopathological significance of BGP expression in non-small-cell lung carcinoma: relationship with histological type, microvessel density and patients' survival. (PubMed id 17393985)1, 9 Lee M.K....Sol M.Y. (2006)
- Primate rod and cone photoreceptors may differ in glucose accessibility. (PubMed id 7775103)1, 9 Nihira M....Burns M.S. (1995)
- Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2. (PubMed id 8244401)1, 9 Yasuda K....Bell G.I. (1993)
|
External Searches for PYGB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PYGB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PYGB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PYGB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PYGB | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PYGB gene:
Search GeneIP for patents involving PYGB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PYGB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PYGB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PYGB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PYGB | | | OriGene Protein Over-expression Lysate for PYGB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PYGB | | OriGene 3'-UTR Clone for PYGB | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PYGB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PYGB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PYGB | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PYGB | | OriGene Custom Protein Services for PYGB | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PYGB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PYGB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PYGB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PYGB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PYGB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PYGB |
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| | | | Search Tocris compounds for PYGB |
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 | | | PYGB Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PYGB |
|  |  |  | | | | ThermoFisher Antibodies for PYGB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PYGB |
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