Aliases for PYDC1 Gene
External Ids for PYDC1 Gene
Previous GeneCards Identifiers for PYDC1 Gene
GeneCards Summary for PYDC1 Gene
PYDC1 (Pyrin Domain Containing 1) is a Protein Coding gene. Diseases associated with PYDC1 include Black Piedra and Listeriosis. Among its related pathways are Toll-Like receptor Signaling Pathways. An important paralog of this gene is PYCARD.
UniProtKB/Swiss-Prot for PYDC1 Gene
Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.