Aliases for PYDC1 Gene
External Ids for PYDC1 Gene
Previous GeneCards Identifiers for PYDC1 Gene
GeneCards Summary for PYDC1 Gene
PYDC1 (PYD (Pyrin Domain) Containing 1) is a Protein Coding gene. Diseases associated with PYDC1 include black piedra and peptic ulcer perforation. Among its related pathways are Gene Expression and RNA transport. An important paralog of this gene is PYCARD.
UniProtKB/Swiss-Prot for PYDC1 Gene
Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.