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Aliases for PYCR2 Gene

Aliases for PYCR2 Gene

  • Pyrroline-5-Carboxylate Reductase 2 2 3 5
  • Pyrroline-5-Carboxylate Reductase Family Member 2 2 3
  • P5C Reductase 2 3 4
  • EC 1.5.1.2 4 58
  • Pyrroline 5-Carboxylate Reductase Isoform 3
  • P5CR 2 4
  • HLD10 3
  • P5CR2 3

External Ids for PYCR2 Gene

Previous GeneCards Identifiers for PYCR2 Gene

  • GC01M223083
  • GC01M222415
  • GC01M224174
  • GC01M226074
  • GC01M196625
  • GC01M226107

Summaries for PYCR2 Gene

Entrez Gene Summary for PYCR2 Gene

  • This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]

GeneCards Summary for PYCR2 Gene

PYCR2 (Pyrroline-5-Carboxylate Reductase 2) is a Protein Coding gene. Diseases associated with PYCR2 include Leukodystrophy, Hypomyelinating, 10 and Visual Cortex Disease. Among its related pathways are Metabolism and Arginine and proline metabolism. GO annotations related to this gene include NAD binding and pyrroline-5-carboxylate reductase activity. An important paralog of this gene is PYCR1.

UniProtKB/Swiss-Prot for PYCR2 Gene

  • Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress (PubMed:25865492).

Additional gene information for PYCR2 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PYCR2 Gene

Genomics for PYCR2 Gene

Regulatory Elements for PYCR2 Gene

Enhancers for PYCR2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H225887 1.4 Ensembl ENCODE dbSUPER 30.1 +34.7 34675 4 FOXA2 ATF1 MLX KLF17 THRB RARA YY1 ZNF121 FOS CREM PYCR2 LEFTY1 LEFTY2 TMEM63A ENSG00000255835 ENSG00000248322 DNAH14
GH01H225846 1.5 Ensembl ENCODE dbSUPER 27.1 +76.1 76123 4 HDGF ARID4B ZNF2 GLIS2 RUNX3 SP3 REST ZNF491 MYNN GLIS1 PYCR2 LEFTY1 LEFTY2 TMEM63A ACBD3 ENSG00000255835 ENSG00000248322 ACBD3-AS1 ENSG00000242861
GH01H225921 1.4 ENCODE dbSUPER 26.7 +0.7 702 3 HDGF PKNOX1 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B ACBD3 PYCR2 ENAH SDE2 LINC01703 ACBD3-AS1 LEFTY1 MIR6741 ENSG00000255835
GH01H225874 1.9 FANTOM5 Ensembl ENCODE dbSUPER 16.9 +45.2 45180 10 FOXA2 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF143 FOS ZNF548 LEFTY2 ACBD3 PYCR2 TMEM63A LEFTY1 ENSG00000255835 ENSG00000248322 SDE2 H3F3A ENSG00000242861
GH01H225459 2 FANTOM5 Ensembl ENCODE dbSUPER 10.8 +459.8 459818 9 PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZNF766 ZNF143 ZNF207 SP3 ZNF592 LBR ACBD3 RPL34P7 LOC105373110 ACBD3-AS1 PYCR2 ENSG00000255835 LEFTY2 ENSG00000248322 ENAH
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PYCR2 on UCSC Golden Path with GeneCards custom track

Promoters for PYCR2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000021044 140 1601 HDGF MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B YY1

Genomic Location for PYCR2 Gene

Chromosome:
1
Start:
225,919,877 bp from pter
End:
225,924,340 bp from pter
Size:
4,464 bases
Orientation:
Minus strand

Genomic View for PYCR2 Gene

Genes around PYCR2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PYCR2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PYCR2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PYCR2 Gene

Proteins for PYCR2 Gene

  • Protein details for PYCR2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96C36-P5CR2_HUMAN
    Recommended name:
    Pyrroline-5-carboxylate reductase 2
    Protein Accession:
    Q96C36
    Secondary Accessions:
    • A8K798
    • Q7Z515
    • Q9Y5J4

    Protein attributes for PYCR2 Gene

    Size:
    320 amino acids
    Molecular mass:
    33637 Da
    Quaternary structure:
    • Homodecamer; composed of 5 homodimers.

neXtProt entry for PYCR2 Gene

Selected DME Specific Peptides for PYCR2 Gene

Q96C36:
  • TVYATGTHA
  • HSDVLFLAVKPHIIPFILDEI
  • ALDALADGGVKMGLPRRLA
  • LLGAAKML
  • SPGGATIHALH
  • LESGGFRSLLI
  • LLEQLMSSVGFCTEVEEDLIDA
  • TGLSGSGPAY

Post-translational modifications for PYCR2 Gene

  • Ubiquitination at isoforms=116 and Lys307
  • Modification sites at PhosphoSitePlus

Other Protein References for PYCR2 Gene

Domains & Families for PYCR2 Gene

Gene Families for PYCR2 Gene

Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins

Graphical View of Domain Structure for InterPro Entry

Q96C36

UniProtKB/Swiss-Prot:

P5CR2_HUMAN :
  • Belongs to the pyrroline-5-carboxylate reductase family.
Family:
  • Belongs to the pyrroline-5-carboxylate reductase family.
genes like me logo Genes that share domains with PYCR2: view

Function for PYCR2 Gene

Molecular function for PYCR2 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.64 mM for NADH {ECO:0000269 PubMed:2722838}; KM=0.04 mM for NADPH {ECO:0000269 PubMed:2722838}; KM=1.49 mM for pyrroline-5-carboxylate (in the presence of NADH) {ECO:0000269 PubMed:2722838}; KM=0.23 mM for pyrroline-5-carboxylate (in the presence of NADPH) {ECO:0000269 PubMed:2722838}; Vmax=28.5 umol/min/ug enzyme (in the presence of NADH) {ECO:0000269 PubMed:2722838}; Vmax=3.7 umol/min/ug enzyme (in the presence of NADPH) {ECO:0000269 PubMed:2722838};
UniProtKB/Swiss-Prot CatalyticActivity:
L-proline + NAD(P)(+) = 1-pyrroline-5-carboxylate + NAD(P)H.
UniProtKB/Swiss-Prot EnzymeRegulation:
Subject to competitive inhibition by NADP. Not inhibited by proline.
UniProtKB/Swiss-Prot Function:
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress (PubMed:25865492).

Enzyme Numbers (IUBMB) for PYCR2 Gene

Phenotypes From GWAS Catalog for PYCR2 Gene

Gene Ontology (GO) - Molecular Function for PYCR2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004735 pyrroline-5-carboxylate reductase activity EXP 23024808
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with PYCR2: view
genes like me logo Genes that share phenotypes with PYCR2: view

Human Phenotype Ontology for PYCR2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for PYCR2 Gene

MGI Knock Outs for PYCR2:

Animal Model Products

CRISPR Products

miRNA for PYCR2 Gene

miRTarBase miRNAs that target PYCR2

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for PYCR2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Transcription Factor Targets and HOMER Transcription for PYCR2 Gene

Localization for PYCR2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PYCR2 Gene

Cytoplasm. Mitochondrion.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PYCR2 gene
Compartment Confidence
mitochondrion 5
extracellular 2
cytosol 2
plasma membrane 1
nucleus 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for PYCR2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005739 mitochondrion IDA 23024808
GO:0005759 mitochondrial matrix TAS --
genes like me logo Genes that share ontologies with PYCR2: view

Pathways & Interactions for PYCR2 Gene

genes like me logo Genes that share pathways with PYCR2: view

UniProtKB/Swiss-Prot Q96C36-P5CR2_HUMAN

  • Pathway: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.

Gene Ontology (GO) - Biological Process for PYCR2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006561 proline biosynthetic process IEA,IDA 23024808
GO:0008652 cellular amino acid biosynthetic process IEA,TAS --
GO:0034599 cellular response to oxidative stress IMP 25865492
GO:0055114 oxidation-reduction process IEA --
GO:0055129 L-proline biosynthetic process IEA --
genes like me logo Genes that share ontologies with PYCR2: view

No data available for SIGNOR curated interactions for PYCR2 Gene

Drugs & Compounds for PYCR2 Gene

(5) Drugs for PYCR2 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
L-Proline Approved Nutra Target 0
hydroxyproline Approved, Experimental Pharma 0
NADH Nutra Target 0
NAD Pharma Full agonist, Agonist 0

(7) Additional Compounds for PYCR2 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
nadph
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
  • b-NADPH
53-57-6
1-Pyrroline-5-carboxylic acid
  • (S)-1-pyrroline-5-carboxylate
  • 1-Pyrroline-5-carboxylate
  • 1-Pyrroline-5-carboxylic acid
  • 3,4-Dihydro-2h-pyrrole-2-carboxylate
  • 3,4-Dihydro-2h-pyrrole-2-carboxylic acid
2906-39-0
4-Hydroxy-L-proline
  • (2S)-4-hydroxypyrrolidine-2-carboxylic acid
  • (4S)-4-hydroxy-L-Proline
  • 4-Hydroxy-L-Proline
  • Allo-4-Hydroxy-L-proline
  • Allo-4-Hydroxyproline
30724-02-8
Hydrogen Ion
  • Hydrogen cation
  • Hydron
  • Proton
NADP
  • Adenine-nicotinamide dinucleotide phosphate
  • b-NADP
  • b-Nicotinamide adenine dinucleotide phosphate
  • b-TPN
  • beta-NADP
53-59-8
genes like me logo Genes that share compounds with PYCR2: view

Transcripts for PYCR2 Gene

Unigene Clusters for PYCR2 Gene

Pyrroline-5-carboxylate reductase family, member 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for PYCR2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for PYCR2 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
SP1: - - - - -
SP2: - - - - - -
SP3: - - - - -
SP4: - - -
SP5: - - - - -
SP6: - - - - - -
SP7: - -
SP8:
SP9:

Relevant External Links for PYCR2 Gene

GeneLoc Exon Structure for
PYCR2
ECgene alternative splicing isoforms for
PYCR2

Expression for PYCR2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PYCR2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for PYCR2 Gene

This gene is overexpressed in Skin (12.1), Salivary gland (10.4), and Breast (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PYCR2 Gene



Protein tissue co-expression partners for PYCR2 Gene

NURSA nuclear receptor signaling pathways regulating expression of PYCR2 Gene:

PYCR2

SOURCE GeneReport for Unigene cluster for PYCR2 Gene:

Hs.654718

mRNA Expression by UniProt/SwissProt for PYCR2 Gene:

Q96C36-P5CR2_HUMAN
Tissue specificity: Detected in erythrocytes (at protein level) (PubMed:2722838, PubMed:6894153). Expressed in fetal brain (PubMed:25865492).

Evidence on tissue expression from TISSUES for PYCR2 Gene

  • Skin(4.3)
  • Nervous system(3.9)

Phenotype-based relationships between genes and organs from Gene ORGANizer for PYCR2 Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • integumentary
  • nervous
  • skeletal muscle
  • skeleton
Organs:
Head and neck:
  • brain
  • cerebellum
  • eye
  • eyelid
  • face
  • head
  • skull
Thorax:
  • chest wall
Abdomen:
  • abdominal wall
Limb:
  • foot
  • lower limb
General:
  • skin
  • spinal cord
genes like me logo Genes that share expression patterns with PYCR2: view

Primer Products

No data available for mRNA differential expression in normal tissues for PYCR2 Gene

Orthologs for PYCR2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PYCR2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PYCR2 33
  • 99.58 (n)
dog
(Canis familiaris)
Mammalia -- 34
  • 94 (a)
OneToMany
PYCR2 33
  • 89.27 (n)
cow
(Bos Taurus)
Mammalia PYCR2 33 34
  • 90.94 (n)
rat
(Rattus norvegicus)
Mammalia Pycr2 33
  • 87.81 (n)
mouse
(Mus musculus)
Mammalia Pycr2 33 16 34
  • 87.6 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 87 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 68 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 82 (a)
OneToMany
PYCR2 33
  • 78.11 (n)
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 82 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia pycr1 33
  • 70.43 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.14102 33
zebrafish
(Danio rerio)
Actinopterygii pycr1a 34
  • 76 (a)
ManyToMany
pycr1b 33 34
  • 74.3 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG5840 34
  • 41 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea M153.1 34
  • 47 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PRO3 34
  • 28 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9500 34
  • 51 (a)
OneToMany
Species where no ortholog for PYCR2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PYCR2 Gene

ENSEMBL:
Gene Tree for PYCR2 (if available)
TreeFam:
Gene Tree for PYCR2 (if available)

Paralogs for PYCR2 Gene

Paralogs for PYCR2 Gene

(5) SIMAP similar genes for PYCR2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with PYCR2: view

Variants for PYCR2 Gene

Sequence variations from dbSNP and Humsavar for PYCR2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs372781135 Pathogenic, Leukodystrophy, hypomyelinating, 10 (HLD10) [MIM:616420] 225,922,043(+) GCAGC(A/G)AATCA intron-variant, downstream-variant-500B, reference, missense
rs876657403 Pathogenic, Leukodystrophy, hypomyelinating, 10 (HLD10) [MIM:616420] 225,921,254(-) GCTTC(C/T)GCTCT reference, missense
rs758595075 Pathogenic 225,921,590(+) GCGCC(A/G/T)TGGCA downstream-variant-500B, reference, synonymous-codon, missense
rs886037931 Pathogenic 225,921,209(-) GAACA(C/T)GGTGA reference, stop-gained
rs886037932 Pathogenic 225,921,232(-) TGCAG(C/T)TGAGG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for PYCR2 Gene

Variant ID Type Subtype PubMed ID
esv2762223 CNV gain 21179565
nsv524126 CNV gain 19592680
nsv549267 CNV loss 21841781

Variation tolerance for PYCR2 Gene

Residual Variation Intolerance Score: 9.81% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.41; 8.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PYCR2 Gene

Human Gene Mutation Database (HGMD)
PYCR2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PYCR2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PYCR2 Gene

Disorders for PYCR2 Gene

MalaCards: The human disease database

(5) MalaCards diseases for PYCR2 Gene - From: HGMD, OMIM, ClinVar, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
leukodystrophy, hypomyelinating, 10
  • hypomyelinating leukodystrophy 10
visual cortex disease
  • visual cortex dysfunction
visual pathway disease
  • disorder of visual pathways
hypomyelinating leukodystrophy
  • hld
microcephaly
  • microcephalus
- elite association - COSMIC cancer census association via MalaCards
Search PYCR2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

P5CR2_HUMAN
  • Leukodystrophy, hypomyelinating, 10 (HLD10) [MIM:616420]: An autosomal recessive neurologic disorder characterized by postnatal microcephaly, severely delayed psychomotor development, hypomyelination, and reduced cerebral white-matter volume. {ECO:0000269 PubMed:25865492}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for PYCR2

Genetic Association Database (GAD)
PYCR2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PYCR2
genes like me logo Genes that share disorders with PYCR2: view

No data available for Genatlas for PYCR2 Gene

Publications for PYCR2 Gene

  1. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. (PMID: 25865492) Nakayama T … Mochida GH (American journal of human genetics 2015) 3 4 60
  2. Functional specialization in proline biosynthesis of melanoma. (PMID: 23024808) De Ingeniis J … Smith JW (PloS one 2012) 3 4 60
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60

Products for PYCR2 Gene

Sources for PYCR2 Gene

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