PYCR2 Gene
protein-coding GIFtS: 54
GCID: GC01M226107
|
|
pyrroline-5-carboxylate reductase family, member 2
| |
Aliases
for PYCR2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Pyrroline-5-Carboxylate Reductase Family, Member 21 2 | | Pyrroline 5-Carboxylate Reductase Isoform2 | | P5CR21 2 | | Pyrroline-5-Carboxylate Reductase 22 | | P5C Reductase 22 3 | | P5CR 23 | | EC 1.5.1.23 8 | | |
Export aliases for PYCR2 gene to outside databasesPrevious GC identifers: GC01M223083 GC01M222415 GC01M224174 GC01M226074 GC01M196625 |
Summaries
for PYCR2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PYCR2:
This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes theconversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternativelyspliced transcript variants have been described for this gene. (provided by RefSeq, Nov 2012)
UniProtKB/Swiss-Prot: P5CR2_HUMAN, Q96C36Function: Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such aserythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higheraffinity for NADP, but higher catalytic efficiency with NADH
|
Genomic Views
for PYCR2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PYCR2 gene promoter:
Elk-1 Pax-5 RelA AP-2gamma NF-kappaB Roaz E47 Pax-3 Hand1 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PYCR2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PYCR2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q42.12 Ensembl cytogenetic band: 1q42.12 HGNC cytogenetic band: 1q42.13PYCR2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M226107: view genomic region
(about GC identifiers)
Start:
|
226,107,578 bp from pter |
End:
|
226,111,978 bp from pter |
Size:
|
4,401 bases |
Orientation:
|
minus strand |
|
Proteins
for PYCR2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: P5CR2_HUMAN, Q96C36 (See
protein sequence)Recommended Name: Pyrroline-5-carboxylate reductase 2 Size: 320 amino acids; 33637 Da
Subunit: Homodecamer; composed of 5 homodimers (Probable)
Subcellular location: Cytoplasm
Secondary accessions: A8K798 Q7Z515 Q9Y5J4Explore the universe of human proteins at neXtProt for PYCR2: NX_Q96C36
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96C36
4/8 DME Specific Peptides for PYCR2 (Q96C36) (see all 8)
PYCR2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001258610.1 NP_037460.2
ENSEMBL proteins: ENSP00000342502
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
PYCR2 for ontologies About GeneDecksing
PYCR2 Antibody Products:
Assay Products for PYCR2: |
Protein
Domains /
Families
for PYCR2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PYCR2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96C36ProtoNet protein and cluster: Q96C36 1 Blocks protein family: IPB000304 Delta 1-pyrroline-5-carboxylate reductase
UniProtKB/Swiss-Prot: P5CR2_HUMAN, Q96C36Similarity: Belongs to the pyrroline-5-carboxylate reductase family |
Function
for PYCR2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: P5CR2_HUMAN, Q96C36Function: Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such aserythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higheraffinity for NADP, but higher catalytic efficiency with NADHCatalytic activity: L-proline + NAD(P)(+) = 1-pyrroline-5-carboxylate + NAD(P)HEnzyme regulation: Subject to competitive inhibition by NADP. Not inhibited by prolineBiophysicochemical properties: Kinetic parameters: KM=0.64 mM for NADH; KM=0.04 mM for NADPH; KM=1.49 mM forpyrroline-5-carboxylate (in the presence of NADH); KM=0.23 mM for pyrroline-5-carboxylate (in the presence of NADPH);Vmax=28.5 umol/min/ug enzyme (in the presence of NADH); Vmax=3.7 umol/min/ug enzyme (in the presence of NADPH);Enzyme Number (IUBMB): EC 1.5.1.21 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PYCR2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PYCR2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PYCR2 (NM_013328) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PYCR2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PYCR2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PYCR2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0004735 | pyrroline-5-carboxylate reductase activity |
IEA | -- |
PYCR2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for PYCR2:
|
Pathways & Interactions
for PYCR2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Arginine and proline metabolism | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Kegg Pathways (Kegg details for PYCR2):
UniProtKB/Swiss-Prot: P5CR2_HUMAN, Q96C36Pathway: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1
PYCR2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PYCR2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/248 Interacting proteins for PYCR2 (Q96C362, 3 ENSP000003425024) via UniProtKB, MINT, STRING, and/or I2D (see all 248)
About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0055129 | L-proline biosynthetic process |
IEA | -- |
PYCR2 for ontologies About GeneDecksing
|
Drugs & Compounds
for PYCR2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PYCR2 for compounds About GeneDecksing
 Browse Tocris compounds for PYCR2
9 HMDB Compounds for PYCR2 About this table
2 DrugBank Compounds for PYCR2 About this table
3 Novoseek chemical compound relationships for PYCR2 gene About this table
Search CenterWatch for drugs/clinical trials and news about PYCR2 / P5CR2
|
Transcripts
for PYCR2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PYCR2 gene (2 alternative transcripts): NM_001271681.1 NM_013328.3 Unigene Cluster for PYCR2: Pyrroline-5-carboxylate reductase family, member 2 Hs.654718 [show with all ESTs]Unigene Representative Sequence: NM_0133288 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000343818 ENST00000478402(uc001hpq.3) ENST00000466127 ENST00000446534(uc001hps.1)
ENST00000489681 ENST00000472798 ENST00000467298 ENST00000366823
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PYCR2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PYCR2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PYCR2 (NM_013328) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PYCR2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PYCR2 |
Additional cDNA sequence: AF087859.1 AF151351.1 AK291913.1 AL834217.1 BC014868.1 BC020553.1 17 DOTS entries: DT.92461963 DT.100814900 DT.121349843 DT.100814902 DT.444679 DT.95340144 DT.100814895 DT.95369130 DT.100814907 DT.95369125 DT.100029866 DT.100814906 DT.40257593 DT.75161188 DT.95369127 DT.121349881 DT.121349882 24/388 AceView cDNA sequences (see all 388): BI820453 BI522700 BI771859 CA843837 BU631076 AI189379 CD366223 BM920663 CR621692 BM830850 AL540521 BU538765 CA454903 CA427188 BU634518 CR625163 BI910857 CR611703 BQ573725 AI298884 BI764446 CR610157 AL543745 CR591913
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for PYCR2 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | | | - | | - | | - | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for PYCR2
|
Expression
for PYCR2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PYCR2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGGAAGTTG
About this image
See PYCR2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PYCR2
SOURCE GeneReport for Unigene cluster: Hs.654718
UniProtKB/Swiss-Prot: P5CR2_HUMAN, Q96C36Tissue specificity: Detected in erythrocytes (at protein level)
SABiosciences Custom PCR Arrays for PYCR2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PYCR2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PYCR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PYCR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PYCR2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PYCR2 |
Orthologs
for PYCR2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for PYCR2 gene from 9/32 species (see all 32) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
PYCR21 |
pyrroline-5-carboxylate reductase family, member 2 |
78.11(n)
85.81(a) |
|
769203 XM_001232431.2 XP_001232432.2 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
79(a) |
1 → many |
2(118427590-118439179) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.141022 |
Xenopus laevis transcribed sequence with moderate similarity more |
73.67(n) |
|
AW638347.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc:1106551 |
zgc:110655 |
74.3(n)
81.48(a) |
|
100149838 NM_001020618.1 NP_001018454.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG58406P5cr6 |
Pyrroline 5-carboyxlate reductase |
41(a)39(a) |
possible orthologpossible ortholog |
3R(13360537-13362858) 3R(14854659-14855881) |
worm
(Caenorhabditis elegans) |
Secernentea |
M153.16F55G1.96 |
Putative pyrroline-5-carboxylate reductase |
46(a)26(a) |
possible orthologpossible ortholog |
X(12146749-12148403) IV(7476157-7477333) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
EMB27726 |
Pyrroline-5-carboxylate reductase |
42(a) |
1 → many |
5(4785960-4787839) |
rice
(Oryza sativa) |
Liliopsida |
-- |
pyrroline-5-carboxylate reductase, putative, expre... |
39(a) |
1 → many |
1(41716973-41720531) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
proC6 |
pyrroline-5-carboxylate reductase, NAD(P)-binding |
37(a) |
1 → many |
Chromosome(404059-404868) |
ENSEMBL Gene Tree for PYCR2 (if available)
TreeFam Gene Tree for PYCR2 (if available) |
Paralogs
for PYCR2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PYCR2 gene
- ENSG000002558352 PYCR12 PYCRL2
5 SIMAP similar genes for PYCR2 using alignment to 2 protein entries: P5CR2_HUMAN (see all proteins):PIG45 PYCR1 P5CR2 PYCRL DKFZp434J218
PYCR2 for paralogs About GeneDecksing
|
Genomic Variants
for PYCR2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PYCR2 (226107578 - 226111978 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PYCR2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PYCR2 |
|
Disorders
/ Diseases
for PYCR2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PYCR2 for disorders About GeneDecksing
6  diseases for PYCR2: About MalaCardsgyrate atrophy ataxia pneumonia tuberculosis
malaria mycobacterium tuberculosis
1 disease from the University of Copenhagen DISEASES database for PYCR2:Cutis laxa Export disorders for PYCR2 gene to outside databases
|
Publications
for PYCR2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PYCR2 gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with PYCR2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Functional specialization in proline biosynthesis of m elanoma. (PubMed id 23024808)1 De Ingeniis J....Smith J.W. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
|
External Searches for PYCR2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PYCR2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PYCR2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PYCR2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PYCR2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PYCR2 gene:
Search GeneIP for patents involving PYCR2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PYCR2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for PYCR2 | | OriGene shRNA RFP for PYCR2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PYCR2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PYCR2 | | | OriGene Protein Over-expression Lysate for PYCR2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PYCR2 | | OriGene 3'-UTR Clone for PYCR2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PYCR2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PYCR2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PYCR2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PYCR2 | | OriGene Custom Protein Services for PYCR2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PYCR2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PYCR2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PYCR2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PYCR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PYCR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PYCR2 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for PYCR2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | PYCR2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PYCR2 |
|  |  |  | | | | Search ThermoFisher Antibodies for PYCR2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PYCR2 |
|
|
|
|
