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PXMP2 Gene

protein-coding   GIFtS: 53
GCID: GC12P133264

Peroxisomal Membrane Protein 2, 22kDa

(Previous name: peroxisomal membrane protein 2 (22kD))
Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Peroxisomal Membrane Protein 2, 22kDa1 2
22 KDa Peroxisomal Membrane Protein2 3
PMP222 3
Peroxisomal Membrane Protein 2 (22kD)1
Peroxisomal Membrane Protein 22

External Ids:    HGNC: 97161   Entrez Gene: 58272   Ensembl: ENSG000001768947   UniProtKB: Q9NR773   

Export aliases for PXMP2 gene to outside databases

Previous GC identifers: GC00U990301 GC12M132864 GC12P132889 GC12P131503 GC12P131874 GC12P131774


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PXMP2 Gene:
PXMP2 (peroxisomal membrane protein 2, 22kDa) is a protein-coding gene. Diseases associated with PXMP2 include parkinson's disease, and ischemia. An important paralog of this gene is MPV17.

UniProtKB/Swiss-Prot: PXMP2_HUMAN, Q9NR77
Function: Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the
peroxisomal membrane




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_024477.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the PXMP2 gene promoter:
         Pbx1a   AML1a   GATA-3   ATF-2   Evi-1   GATA-2   AREB6   MZF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPXMP2 promoter sequence
   Search Chromatin IP Primers for PXMP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PXMP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.33   Ensembl cytogenetic band:  12q24.33   HGNC cytogenetic band: 12q24

PXMP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PXMP2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P133264:  view genomic region     (about GC identifiers)

Start:
133,264,192 bp from pter      End:
133,297,276 bp from pter
Size:
33,085 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PXMP2_HUMAN, Q9NR77 (See protein sequence)
Recommended Name: Peroxisomal membrane protein 2  
Size: 195 amino acids; 22253 Da
Subunit: Interacts with PEX19 and SIVA1

Explore the universe of human proteins at neXtProt for PXMP2: NX_Q9NR77

Explore proteomics data for PXMP2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PXMP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061133.1  
    ENSEMBL proteins: 
     ENSP00000321271   ENSP00000446049   ENSP00000444486   ENSP00000398708   ENSP00000445782  

    PXMP2 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for PXMP2

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    Abcam antibodies for PXMP2
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    ThermoFisher Antibodies for PXMP2
    LSBio Antibodies in human, mouse, rat for PXMP2

    PXMP2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for PXMP2
    Cloud-Clone Corp. CLIAs for PXMP2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007248 Mpv17_PMP22

    Graphical View of Domain Structure for InterPro Entry Q9NR77

    ProtoNet protein and cluster: Q9NR77

    1 Blocks protein domain: IPB007248 Mpv17/PMP22

    UniProtKB/Swiss-Prot: PXMP2_HUMAN, Q9NR77
    Similarity: Belongs to the peroxisomal membrane protein PXMP2/4 family


    PXMP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PXMP2_HUMAN, Q9NR77
    Function: Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the
    peroxisomal membrane

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11590176
         
    PXMP2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for PXMP2:
     Elongated cells with protrusio  Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Pxmp2):
     endocrine/exocrine gland  homeostasis/metabolism  integument  liver/biliary system  renal/urinary system 
     reproductive system 

    PXMP2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PXMP2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PXMP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PXMP2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PXMP2

    miRNA
    Products:
        
    miRTarBase miRNAs that target PXMP2:
    hsa-mir-15b-5p (MIRT046402), hsa-mir-935 (MIRT036675)

    Block miRNA regulation of human, mouse, rat PXMP2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PXMP2
    SwitchGear 3'UTR luciferase reporter plasmidPXMP2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PXMP2
    Predesigned siRNA for gene silencing in human, mouse, rat PXMP2

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for PXMP2 (see all 7)
    OriGene ORF clones in mouse, rat for PXMP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PXMP2 (NM_018663)
    Sino Biological Human cDNA Clone for PXMP2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PXMP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PXMP2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for PXMP2 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PXMP2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PXMP2_HUMAN, Q9NR77: Peroxisome membrane; Multi-pass membrane protein

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA8624723
    GO:0005739mitochondrion IEA--
    GO:0005778peroxisomal membrane IDA11590176
    GO:0016021integral component of membrane IEA--
    GO:0043234protein complex IDA18174172

    PXMP2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PXMP2 About    
    See pathways by source

    SuperPathContained pathways About
    1Peroxisome
    Peroxisome

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for PXMP2):
        Peroxisome


    PXMP2 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including PXMP2: 
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for PXMP2

    2 Interacting proteins for PXMP2 (Q9NR771, 2, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PEX19P408551, 2, 3EBI-1392944,EBI-594747 MINT-8089433 I2D: score=1 
    SIVA1O153041, 3EBI-1392944,EBI-520756 I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    PXMP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PXMP2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PXMP2 gene: 
    NM_018663.2  

    Unigene Cluster for PXMP2:

    Peroxisomal membrane protein 2, 22kDa
    Hs.430299  [show with all ESTs]
    Unigene Representative Sequence: BM454192
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000317479(uc001ukt.3) ENST00000543589 ENST00000539093 ENST00000428960
    ENST00000454379 ENST00000545677

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PXMP2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PXMP2
    SwitchGear 3'UTR luciferase reporter plasmidPXMP2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PXMP2
    Predesigned siRNA for gene silencing in human, mouse, rat PXMP2
    Clone
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    OriGene clones in human, mouse for PXMP2 (see all 7)
    OriGene ORF clones in mouse, rat for PXMP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PXMP2 (NM_018663)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PXMP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PXMP2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PXMP2
    OriGene qSTAR qPCR primer pairs in human, mouse for PXMP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PXMP2
      QuantiTect SYBR Green Assays in human, mouse, rat PXMP2
      QuantiFast Probe-based Assays in human, mouse, rat PXMP2

    Additional mRNA sequence: 

    AF250136.1 AY044439.1 BC009836.1 BC073997.1 

    5 DOTS entries:

    DT.412840  DT.91759817  DT.92005633  DT.100008697  DT.100019760 

    Selected AceView cDNA sequences (see all 81):

    AW445130 BX116473 BU195441 AI627671 BC073997 BQ440491 BM671530 BM704325 
    BE796979 BI963751 CA430320 CB046071 AW603066 CK903708 BE393339 BM857189 
    AF250136 BU624033 AI869066 BU617888 AW419313 AW134610 BF476574 BQ021304 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PXMP2    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
    SP1:                    -                             -                     
    SP2:                    -                                                   
    SP3:                    -                             -                     
    SP4:                                                  -                     


    ECgene alternative splicing isoforms for PXMP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PXMP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACTTTCTGG
    PXMP2 Expression
    About this image


    PXMP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Body Subcutaneous White Adipose
     
     Liver (Hepatobiliary System)
    PXMP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PXMP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.430299
        Pathway & Disease-focused RT2 Profiler PCR Array including PXMP2: 
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PXMP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PXMP2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pxmp21 , 5 peroxisomal membrane protein 21, 5 79.97(n)1
    75.65(a)1
      5 (53.44 cM)5
    193011  NM_008993.21  NP_033019.21 
     1102742825 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.59812 Transcribed sequence with weak similarity to protein more 73.74(n)    137722054 
    zebrafish
    (Danio rerio)
    Actinopterygii pxmp21 peroxisomal membrane protein 2 58.6(n)
    57.37(a)
      447868  NM_001004607.1  NP_001004607.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG79706
    --
    25(a)
    1 ↔ 1
    3L(1653005-1654112)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SYM16
    Protein required for ethanol metabolism; induced b...
    26(a)
    1 → many
    XII(641464-642057) YLR251W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G197501 AT5G19750 46.75(n)
    34.76(a)
      832095  NM_121980.3  NP_197476.1 


    ENSEMBL Gene Tree for PXMP2 (if available)
    TreeFam Gene Tree for PXMP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PXMP2 gene
    MPV172  MPV17L22  
    1 SIMAP similar gene for PXMP2 using alignment to 5 protein entries:     PXMP2_HUMAN (see all proteins):
    MPV17

    PXMP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PXMP2 (see all 579)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs124224921,2
    C,H--130041222(+) TATATA/CACACC 1 -- us2k12Minor allele frequency- C:0.25NA WA 4
    rs1924899581,2
    --130041266(+) AGCTAA/CCATTG 1 -- us2k10--------
    rs1824755451,2
    --130041358(+) ACACTA/GTCCCA 1 -- us2k10--------
    rs111470051,2
    C,F,A,H--130041473(+) CCCTAT/CGAGGG 1 -- us2k128Minor allele frequency- C:0.47NS EA NA WA CSA 2761
    rs734851031,2
    C,F--130041520(+) GCAGGC/TAAACA 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1154484561,2
    C,F--130041610(+) AAGGTA/CAAAGC 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1142630991,2
    F--130041655(+) CCTGCC/GTGGAG 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs118380971,2
    C,F,H--133266175(+) AGGTCC/TGTGCT 1 -- int111Minor allele frequency- T:0.05NS EA NA CSA WA 1212
    rs1173202951,2
    F--133266203(+) TAGTCC/TAGAGA 1 -- int11Minor allele frequency- T:0.03EA 120
    rs744646881,2
    C,F--133266212(+) GAGCTT/GCTCAG 1 -- int11Minor allele frequency- G:0.09WA 118

    HapMap Linkage Disequilibrium report for PXMP2 (133264192 - 133297276 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for PXMP2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2747033CNV Deletion23290073
    esv2747034CNV Deletion23290073
    nsv820594CNV Deletion20802225
    esv2422284CNV Deletion17116639
    nsv512304CNV Loss21212237
    nsv512305CNV Loss21212237
    dgv1534n71CNV Loss21882294
    nsv899827CNV Gain21882294
    esv25236CNV Gain19812545
    esv24887CNV Gain+Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PXMP2
    DNA2.0 Custom Variant and Variant Library Synthesis for PXMP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for PXMP2:    
    About MalaCards
    parkinson's disease    ischemia    malaria


    PXMP2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for PXMP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PXMP2 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with PXMP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes. (PubMed id 11590176)1, 2, 3, 9 Brosius U.... Gaertner J. (J. Biol. Chem. 2002)
    2. The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22. (PubMed id 16683188)1, 2 Nestler M....Munder T. (Mol. Cell. Biochem. 2006)
    3. PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. (PubMed id 10704444)1, 2 Sacksteder K.A.... Gould S.J. (J. Cell Biol. 2000)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Characterization of the interaction between recombinant human peroxin Pex3p and Pex19p: identification of TRP-104 IN Pex3p as a critical residue for the interaction. (PubMed id 18174172)1 Sato Y....Kato H. (J. Biol. Chem. 2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Developmental immunohistochemistry of the 22 kDa peroxisomal membrane protein in the human brain. (PubMed id 8624723)1 Miyawaki T....Takashima S. (Brain Res. 1995)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5827 HGNC: 9716 AceView: PXMP2 Ensembl:ENSG00000176894 euGenes: HUgn5827
    ECgene: PXMP2 Kegg: 5827 H-InvDB: PXMP2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PXMP2 Pharmacogenomics, SNPs, Pathways

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