Subcategory (RNA class) for PVT1 Gene
Quality Score for this RNA gene is
Aliases for PVT1 Gene
Previous GeneCards Identifiers for PVT1 Gene
This gene represents a long non-coding RNA locus that has been identified as a candidate oncogene. Increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Allelic variants of this gene are also associated with end-stage renal disease attributed to type 1 diabetes. Consistent with its association with various types of cancer, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. [provided by RefSeq, Sep 2015]
GeneCards Summary for PVT1 Gene
PVT1 (Pvt1 Oncogene (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with PVT1 include plasmacytoma.