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Aliases & Descriptions for PVT1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| MGC21751 2 | | NCRNA00079 1, 2 |
| | | Descriptions |
|---|
| Pvt1 oncogene (non-protein coding) 2 | | Pvt1 oncogene homolog (mouse) 1 | | pvt-1 (murine) oncogene homolog, MYC activator 1 |
|
| | Search outside databases for aliases for PVT1 genePrevious GC identifers: GC08P127815 GC08U900029 GC08P128764 |
Summaries for PVT1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Gene Wiki entry for PVT1 |
Genomic Location for PVT1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the PVT1 gene 
Entrez Gene cytogenetic band: 8q24 HGNC cytogenetic band: 8q24PVT1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P128876:
(about GC identifiers)
Start:
|
128,875,961 bp from pter |
End:
|
129,182,681 bp from pter |
Size:
|
306,721 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000008.9 NT_008046.15
| Proteins for PVT1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for PVT1: Assays for PVT1: | Protein
Domains/ Families for PVT1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- | Gene Function for PVT1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|                  Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Applied Biosystems Silencer® siRNAs for PVT1
Sigma-Aldrich siRNA for PVT1  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
Browse Origene for untagged/tagged cDNA clones in CMV expression vector
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NR_003367
Genatlas biochemistry entry for PVT1:plasmocytoma variant translocation (pvt-1) mouse oncogene homolog,c-myc activator (260kb,3') same as Mis1/MLVI-11 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Pvt1):
| Pathways & Interactions for PVT1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
Gene Network CentralTM Interacting Genes and Proteins Network for PVT1 
-- |
Drugs & Compounds for PVT1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for PVT1
|
Transcripts for PVT1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene) About This Section
|                  Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Sigma-Aldrich siRNA for PVT1  Browse shRNA at Sigma-Aldrich  Explore Sigma-Aldrich super-pooled esiRNAs 
Browse Origene for untagged/tagged cDNA clones in CMV expression vector Additional cDNA sequence: AK128687.1 24/25 DOTS entries (see all 25
): DT.92004143 DT.92017456 DT.452872 DT.100779410 DT.92420191 DT.40111387 DT.95185627 DT.97830246 DT.414396 DT.121477449 DT.75101474 DT.75126784 DT.100699292 DT.409587 DT.91988834 DT.95212182 DT.95370760 DT.92423888 DT.97842278 DT.423212 DT.91955257 DT.92423883 DT.97842279 DT.100739032 24/145 AceView cDNA sequences (see all 145
):BM804818 BM562579 BM781929 BC033263 BC041065 BX104741 BM845333 AI652658 AL556447 CA414499 BX280136 CB104922 BM553007 BM824860 BM809411 CA502872 BE879405 BM821521 CA421444 BM424250 BQ008426 AI498125 BF732344 BX648921
highest scoring ESTs for PVT1:AA586695 M34428 AI498125 AI652658 AL556447 BF772948 BI830530 BC033263 BC041065 AA523800 Unigene Clusters for PVT1: Pvt1 oncogene (non-protein coding) Hs.133107 [show with all ESTs], Hs.675281 [show with all ESTs]Unigene Representative Sequences: BX648921, AK128687
GeneLoc Exon Structure
|
Expression for PVT1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| PVT1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for PVT1
1 / 2 / 3 10 probe-sets matching PVT1 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: CCCAGGTCTG
SOURCE GeneReport for Unigene clusters: Hs.133107 Hs.675281
Expression variation in blood from EXPOLDB for PVT1 |
Orthologs for PVT1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for PVT1 gene from 1 species
| Organism |
Gene |
Locus |
Description |
Human Similarity |
NCBI accessions |
mouse (Mus musculus) |
Pvt15 |
15 (32.00 cM) |
plasmacytoma variant translocation 1 |
-- |
Z12002 |
About this table Species with no ortholog for PVT1 | Paralogs for PVT1(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| -- |
SNPs/Variants for PVT1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations for PVT1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 165140
Genatlas disease: PVT1 Burkitt lymphoma variant/acute lymphoblastic leukemia with translocations t(2;8)(p12;q24);t(8;22)(q24;q11) Human Genome Epidemiology Navigator: PVT1 (2 documents) Tumor Gene Database: PVT1
|
Medical News for PVT1(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for PVT1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/12 PubMed articles for PVT1 gene (see all 12
): |
Search for PVT1
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing PVT1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing PVT1
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PVT1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for PVT1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for PVT1:

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Incremental update: 13 Oct 2009
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