PUS1 Gene
protein-coding GIFtS: 55
GCID: GC12P132413
|
|
pseudouridylate synthase 1
| |
Aliases
for PUS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Pseudouridylate Synthase 11 2 | | Mitochondrial TRNA Pseudouridine Synthase A2 | | TRNA Pseudouridine(38-40) Synthase2 3 | | TRNA Pseudouridine Synthase A, Mitochondrial2 | | TRNA Pseudouridylate Synthase I2 3 | | TRNA Uridine Isomerase I2 | | TRNA-Uridine Isomerase I2 3 | | EC 5.4.99.123 | | MLASA12 5 | | |
Export aliases for PUS1 gene to outside databasesPrevious GC identifers: GC00U990923 GC12M131701 GC12P132294 GC12P130908 GC12P131080 GC12P130980 GC12P129299 |
Summaries
for PUS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PUS1:
This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into anRNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary andtertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblasticanemia. Alternate splicing results in multiple transcript variants.(provided by RefSeq, Sep 2009)
UniProtKB/Swiss-Prot: TRUA_HUMAN, Q9Y606Function: Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodonstem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclearreceptor activity possibly through pseudouridylation of SRA1 RNA (By similarity)
Gene Wiki entry for PUS1
|
Genomic Views
for PUS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009755.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PUS1 gene promoter:
SRF STAT1 AML1a SRF (504 AA) STAT1beta LCR-F1 Tal-1beta STAT1alpha E47 Pax-3
Other transcription factors
Search SABiosciences Chromatin IP Primers for PUS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PUS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.33 Ensembl cytogenetic band: 12q24.33 HGNC cytogenetic band: 12q24PUS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P132413: view genomic region
(about GC identifiers)
Start:
|
132,413,745 bp from pter |
End:
|
132,428,406 bp from pter |
Size:
|
14,662 bases |
Orientation:
|
plus strand |
|
Proteins
for PUS1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRUA_HUMAN, Q9Y606 (See
protein sequence)Recommended Name: tRNA pseudouridine synthase A, mitochondrial precursor Size: 427 amino acids; 47470 Da
Subunit: Forms a complex with RARG and the SRA1 RNA in the nucleus (By similarity)
Subcellular location: Isoform 1: Mitochondrion
Subcellular location: Isoform 2: Nucleus
Secondary accessions: A8K877 B3KQC1 Q8WYT2 Q9BU44Alternative splicing: 2 isoforms: Q9Y606-1 Q9Y606-2 Explore the universe of human proteins at neXtProt for PUS1: NX_Q9Y606
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y606
PUS1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001002019.1 NP_001002020.1 NP_079491.2
ENSEMBL proteins: ENSP00000392451 ENSP00000365837 ENSP00000324726 ENSP00000438948 ENSP00000440326 ENSP00000409705 ENSP00000445819 ENSP00000443969 ENSP00000440179 ENSP00000400032
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
PUS1 for ontologies About GeneDecksing
PUS1 Antibody Products:
Assay Products for PUS1: |
Protein
Domains /
Families
for PUS1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PUS1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y606ProtoNet protein and cluster: Q9Y606 1 Blocks protein family: IPB001406 tRNA pseudouridine synthase
UniProtKB/Swiss-Prot: TRUA_HUMAN, Q9Y606Similarity: Belongs to the tRNA pseudouridine synthase TruA family |
Function
for PUS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TRUA_HUMAN, Q9Y606Function: Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodonstem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclearreceptor activity possibly through pseudouridylation of SRA1 RNA (By similarity)Catalytic activity: tRNA uridine(38-40) = tRNA pseudouridine(38-40)Enzyme Number (IUBMB): EC 5.4.99.121
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PUS1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for PUS1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PUS1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PUS1 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
PUS1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for PUS1:
|
Pathways & Interactions
for PUS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PUS1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/291 Interacting proteins for PUS1 (Q9Y6062, 3 ENSP000003658374) via UniProtKB, MINT, STRING, and/or I2D (see all 291)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001522 | pseudouridine synthesis |
-- | -- | | GO:0008033 | tRNA processing |
NAS | -- | | GO:0031119 | tRNA pseudouridine synthesis |
IEA | -- | | GO:0045944 | positive regulation of transcription from RNA polymerase II promoter |
IEA | -- |
PUS1 for ontologies About GeneDecksing
|
Drugs & Compounds
for PUS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PUS1 for compounds About GeneDecksing
 Browse Tocris compounds for PUS1
2 HMDB Compounds for PUS1 About this table
3 Novoseek chemical compound relationships for PUS1 gene About this table
Search CenterWatch for drugs/clinical trials and news about PUS1 / TRUA
|
Transcripts
for PUS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PUS1 gene (3 alternative transcripts): NM_001002019.2 NM_001002020.2 NM_025215.5 Unigene Cluster for PUS1: Pseudouridylate synthase 1 Hs.592004 [show with all ESTs]Unigene Representative Sequence: BC03596412 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000443358(uc001ujg.3) ENST00000376649(uc001ujf.3) ENST00000322060
ENST00000542167(uc001uji.3) ENST00000538037 ENST00000544662 ENST00000456665
ENST00000544213 ENST00000535067 ENST00000537484 ENST00000543754 ENST00000440818(uc001ujh.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PUS1 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PUS1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): PUS1 (NM_001002019) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PUS1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PUS1 |
Additional cDNA sequence: AF116238.1 AF318369.1 AK074659.1 AK292242.1 BC002901.2 BC009505.2 BC019320.1 BC035964.1 15 DOTS entries: DT.446313 DT.65288670 DT.100025436 DT.121190804 DT.100704237 DT.100792100 DT.100704238 DT.100733277 DT.100792096 DT.121190834 DT.95278212 DT.95278213 DT.100704236 DT.100882099 DT.40197786 24/183 AceView cDNA sequences (see all 183): BM980363 BQ221418 AI696918 BI060831 BM560889 AF318369 CA447613 BM727118 BI117220 BM678376 BC019320 AA766938 CA423038 BM726285 BM680891 AW245442 CB270100 BM826687 CB118952 BQ053491 AI566951 BC002901 BM008159 AI362628
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for PUS1 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PUS1
|
Expression
for PUS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PUS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAGAACTA
About this image
See PUS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PUS1
SOURCE GeneReport for Unigene cluster: Hs.592004
UniProtKB/Swiss-Prot: TRUA_HUMAN, Q9Y606Tissue specificity: Widely expressed. High levels of expression found in brain and skeletal muscle
SABiosciences Custom PCR Arrays for PUS1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PUS1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PUS1 |
Orthologs
for PUS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for PUS1 gene from 10/35 species (see all 35) About this table
ENSEMBL Gene Tree for PUS1 (if available)
TreeFam Gene Tree for PUS1 (if available) |
Paralogs
for PUS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for PUS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PUS1 (132413745 - 132428406 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for PUS1
1 CNV: 8742
Human Gene Mutation Database (HGMD): PUS1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PUS1 |
|
Disorders
/ Diseases
for PUS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PUS1 for disorders About GeneDecksing
OMIM gene information: 608109
OMIM disorders: 600462
UniProtKB/Swiss-Prot: TRUA_HUMAN, Q9Y606
Defects in PUS1 are a cause of myopathy with lactic acidosis and sideroblastic anemia type 1 (MLASA1)[MIM:600462]; also known as mitochondrial myopathy and sideroblastic anemia. MLASA is a rare autosomal recessiveoxidative phosphorylation disorder specific to skeletal muscle and bone marrow
11  diseases for PUS1: About MalaCardsmitochondrial myopathy and sideroblastic anemia sideroblastic anemia myopathy anemia
mitochondrial myopathy and sideroblastic anemia 1 lactic acidosis pearson syndrome aplastic anemia
intrahepatic cholangiocarcinoma cholangiocarcinoma malaria
3 diseases from the University of Copenhagen DISEASES database for PUS1:Sideroblastic anemia Mitochondrial myopathy Pearson syndrome 4 Novoseek disease relationships for PUS1 gene About this table
Export disorders for PUS1 gene to outside databases
|
Publications
for PUS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PUS1 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with PUS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of a mammalian pseudouridine synthase. (PubMed id 10094309)1, 2, 3, 9 Chen J. and Patton J.R. (1999)
- Nonsense mutation in pseudouridylate synthase 1 (PUS1) in two brothers affected by myopathy, lactic acidosis and sideroblastic anaemia (MLASA). (PubMed id 17056637)1, 2, 9 Fernandez-Vizarra E....Zeviani M. (2007)
- Missense mutation in pseudouridine synthase 1 (PUS1) causes mitochondrial myopathy and sideroblastic anemia (MLASA). (PubMed id 15108122)1, 2, 9 Bykhovskaya Y.... Fischel-Ghodsian N. (2004)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Mitochondrial myopathy and sideroblastic anemia (MLASA): missense mutation in the pseudouridine synthase 1 (PUS1) gene is associated with the loss of tRNA pseudouridylation. (PubMed id 15772074)1, 9 Patton J.R....Fischel-Ghodsian N. (2005)
- Systematic molecular genetic analysis of congenital s ideroblastic anemia: evidence for genetic heterogeneity and identification of n ovel mutations. (PubMed id 19731322)1, 9 Bergmann A.K....Neufeld E.J. (2010)
- Partial activity is seen with many substitutions of highly conserved active site residues in human Pseudouridine synthase 1. (PubMed id 18648068)1, 9 Sibert B.S....Patton J.R. (2008)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
|
External Searches for PUS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PUS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PUS1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PUS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PUS1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PUS1 gene:
Search GeneIP for patents involving PUS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PUS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PUS1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PUS1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PUS1 | | | OriGene Protein Over-expression Lysate for PUS1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PUS1 | | OriGene 3'-UTR Clone for PUS1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PUS1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PUS1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PUS1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PUS1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PUS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PUS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PUS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PUS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PUS1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for PUS1 |
| |  |  |  |  | | | | |
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 |
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 | | | PUS1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PUS1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PUS1 |
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