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Aliases for PTTG3P Gene

Aliases for PTTG3P Gene

  • Pituitary Tumor-Transforming 3, Pseudogene 2 3
  • RcPTTG1 3 4
  • PTTG3 3 4
  • Pituitary Tumor-Transforming 3 (Pseudogene) 3
  • Pituitary Tumor-Transforming 3 2
  • Securin-3 4
  • HPTTG3 4

External Ids for PTTG3P Gene

Previous HGNC Symbols for PTTG3P Gene

  • PTTG3

Previous GeneCards Identifiers for PTTG3P Gene

  • GC08M067843
  • GC08M067680
  • GC08M063171

Summaries for PTTG3P Gene

GeneCards Summary for PTTG3P Gene

PTTG3P (Pituitary Tumor-Transforming 3, Pseudogene) is a Pseudogene. Among its related pathways are Cell cycle. GO annotations related to this gene include SH3 domain binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PTTG3P Gene

Genomics for PTTG3P Gene

Genomic Location for PTTG3P Gene

Chromosome:
8
Start:
66,767,397 bp from pter
End:
66,768,005 bp from pter
Size:
609 bases
Orientation:
Minus strand

Genomic View for PTTG3P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PTTG3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PTTG3P Gene

No data available for Regulatory Elements for PTTG3P Gene

Proteins for PTTG3P Gene

  • Protein details for PTTG3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NZH4-PTTG3_HUMAN
    Recommended name:
    Putative pituitary tumor-transforming gene 3 protein
    Protein Accession:
    Q9NZH4
    Secondary Accessions:
    • O95356

    Protein attributes for PTTG3P Gene

    Size:
    202 amino acids
    Molecular mass:
    22064 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PTTG3P Gene

Proteomics data for PTTG3P Gene at MOPED

Post-translational modifications for PTTG3P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for PTTG3P Gene

Domains & Families for PTTG3P Gene

Protein Domains for PTTG3P Gene

Suggested Antigen Peptide Sequences for PTTG3P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NZH4

UniProtKB/Swiss-Prot:

PTTG3_HUMAN :
  • The N-terminal destruction box (D-box) acts as a recognition signal for degradation via the ubiquitin-proteasome pathway.
  • Belongs to the securin family.
Domain:
  • The N-terminal destruction box (D-box) acts as a recognition signal for degradation via the ubiquitin-proteasome pathway.
Family:
  • Belongs to the securin family.
genes like me logo Genes that share domains with PTTG3P: view

No data available for Gene Families for PTTG3P Gene

Function for PTTG3P Gene

Gene Ontology (GO) - Molecular Function for PTTG3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0017124 SH3 domain binding IEA --
GO:0030414 peptidase inhibitor activity IBA --
genes like me logo Genes that share ontologies with PTTG3P: view

Phenotypes for PTTG3P Gene

GenomeRNAi human phenotypes for PTTG3P:
genes like me logo Genes that share phenotypes with PTTG3P: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PTTG3P Gene

Localization for PTTG3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for PTTG3P Gene

Cytoplasm. Nucleus.

Gene Ontology (GO) - Cellular Components for PTTG3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with PTTG3P: view

No data available for Subcellular locations from COMPARTMENTS for PTTG3P Gene

Pathways & Interactions for PTTG3P Gene

SuperPathways for PTTG3P Gene

Superpath Contained pathways
1 Cell cycle
genes like me logo Genes that share pathways with PTTG3P: view

Pathways by source for PTTG3P Gene

1 BioSystems pathway for PTTG3P Gene

Interacting Proteins for PTTG3P Gene

Gene Ontology (GO) - Biological Process for PTTG3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0010466 negative regulation of peptidase activity IBA --
GO:0045143 homologous chromosome segregation IBA --
GO:0051276 chromosome organization IEA --
GO:2000816 negative regulation of mitotic sister chromatid separation IBA --
genes like me logo Genes that share ontologies with PTTG3P: view

No data available for SIGNOR curated interactions for PTTG3P Gene

Drugs & Compounds for PTTG3P Gene

No Compound Related Data Available

Transcripts for PTTG3P Gene

mRNA/cDNA for PTTG3P Gene

(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PTTG3P Gene

No ASD Table

Relevant External Links for PTTG3P Gene

GeneLoc Exon Structure for
PTTG3P
ECgene alternative splicing isoforms for
PTTG3P

Expression for PTTG3P Gene

mRNA expression in normal human tissues for PTTG3P Gene

Protein differential expression in normal tissues from HIPED for PTTG3P Gene

This gene is overexpressed in Retina (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PTTG3P Gene



SOURCE GeneReport for Unigene cluster for PTTG3P Gene Hs.647156

mRNA Expression by UniProt/SwissProt for PTTG3P Gene

Q9NZH4-PTTG3_HUMAN
Tissue specificity: Expressed in ovarian tumor and tumor cell lines (SK-OV-3 and PA1).
genes like me logo Genes that share expression patterns with PTTG3P: view

Protein tissue co-expression partners for PTTG3P Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for PTTG3P Gene

Orthologs for PTTG3P Gene

Evolution for PTTG3P Gene

ENSEMBL:
Gene Tree for PTTG3P (if available)
TreeFam:
Gene Tree for PTTG3P (if available)

No data available for Orthologs for PTTG3P Gene

Paralogs for PTTG3P Gene

(3) SIMAP similar genes for PTTG3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PTTG3P: view

No data available for Paralogs for PTTG3P Gene

Variants for PTTG3P Gene

Relevant External Links for PTTG3P Gene

HapMap Linkage Disequilibrium report
PTTG3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for PTTG3P Gene

Disorders for PTTG3P Gene

Relevant External Links for PTTG3P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PTTG3P
genes like me logo Genes that share disorders with PTTG3P: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PTTG3P Gene

Publications for PTTG3P Gene

  1. Identification of the human pituitary tumor transforming gene (hPTTG) family: molecular structure, expression, and chromosomal localization. (PMID: 10806349) Chen L. … Kakar S.S. (Gene 2000) 2 67
  2. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 67
  3. Emergence of young human genes after a burst of retroposition in primates. (PMID: 16201836) Marques A.C. … Kaessmann H. (PLoS Biol. 2005) 67

Products for PTTG3P Gene

Sources for PTTG3P Gene

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