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Aliases for PTPRJ Gene

Aliases for PTPRJ Gene

  • Protein Tyrosine Phosphatase, Receptor Type J 2 3 5
  • Protein-Tyrosine Phosphatase Eta 3 4
  • Density-Enhanced Phosphatase 1 3 4
  • CD148 Antigen 3 4
  • EC 3.1.3.48 4 61
  • R-PTP-ETA 3 4
  • HPTP Eta 3 4
  • R-PTP-J 3 4
  • DEP-1 3 4
  • DEP1 3 4
  • Protein Tyrosine Phosphatase, Receptor Type, J Polypeptide 3
  • Susceptibility To Colon Cancer 1, Mouse, Homolog Of 3
  • Receptor-Type Tyrosine-Protein Phosphatase Eta 3
  • Protein-Tyrosine Phosphatase Receptor Type J 4
  • Human Density Enhanced Phosphatase-1 3
  • HPTPeta 3
  • CD148 3
  • SCC1 3

External Ids for PTPRJ Gene

Previous GeneCards Identifiers for PTPRJ Gene

  • GC11P049914
  • GC11P048896
  • GC11P048033
  • GC11P047966
  • GC11P047958
  • GC11P047712

Summaries for PTPRJ Gene

Entrez Gene Summary for PTPRJ Gene

  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for PTPRJ Gene

PTPRJ (Protein Tyrosine Phosphatase, Receptor Type J) is a Protein Coding gene. Diseases associated with PTPRJ include Colorectal Cancer and Precursor B Lymphoblastic Lymphoma/Leukemia. Among its related pathways are Immune System and Development HGF signaling pathway. GO annotations related to this gene include protein kinase binding and protein tyrosine phosphatase activity. An important paralog of this gene is PTPRB.

UniProtKB/Swiss-Prot for PTPRJ Gene

  • Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.

Gene Wiki entry for PTPRJ Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PTPRJ Gene

Genomics for PTPRJ Gene

Regulatory Elements for PTPRJ Gene

Enhancers for PTPRJ Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F047985 1.2 FANTOM5 Ensembl ENCODE 35.5 +24.0 24043 37.6 PKNOX1 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 YY1 FOS SP5 NUP160 FNBP4 ENSG00000200090 ENSG00000270060 DDB2 PTPRJ SLC39A13 MADD ENSG00000256897 KBTBD4
GH11F047945 1.1 FANTOM5 Ensembl ENCODE 23.1 -31.9 -31918 6.1 HDGF PKNOX1 ARNT SIN3A BRCA1 GATA2 ELK1 FOS SMARCB1 MAFF PTPRJ PTPRJ-AS1 CELF1 ACP2 PACSIN3 ARFGAP2 ENSG00000256897 C1QTNF4 MADD FNBP4
GH11F048053 1.3 FANTOM5 Ensembl ENCODE 18 +75.7 75743 5.4 HDAC1 PKNOX1 ZNF133 NFXL1 ZBTB40 GATA2 ETV6 CREM SMARCA5 NCOA1 PTPRJ PTPRJ-AS1 MADD PACSIN3 ACP2 FNBP4 PIR62326 MIR3161
GH11F048028 0.5 Ensembl ENCODE 17.4 +52.3 52343 8.6 PKNOX1 ZNF133 SIN3A ZNF766 FOS NCOA1 JUNB CREB3 NBN KDM1A PTPRJ NUP160 C1QTNF4 ACP2 FAM180B ARFGAP2 PACSIN3 PIR62326 MIR3161
GH11F048087 1.3 Ensembl ENCODE 16.8 +107.7 107744 1.4 HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 YY1 ELK1 ZNF143 JUNB PTPRJ PTPRJ-AS1 NUP160 C1QTNF4 MIR3161 PIR62326
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around PTPRJ on UCSC Golden Path with GeneCards custom track

Promoters for PTPRJ Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000562288 542 2201 PKNOX1 SIN3A RAD21 GLIS2 RCOR1 SP3 TBX21 NR2F2 TFDP1 ZNF341

Genomic Location for PTPRJ Gene

Chromosome:
11
Start:
47,980,558 bp from pter
End:
48,170,842 bp from pter
Size:
190,285 bases
Orientation:
Plus strand

Genomic View for PTPRJ Gene

Genes around PTPRJ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PTPRJ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PTPRJ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PTPRJ Gene

Proteins for PTPRJ Gene

  • Protein details for PTPRJ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q12913-PTPRJ_HUMAN
    Recommended name:
    Receptor-type tyrosine-protein phosphatase eta
    Protein Accession:
    Q12913
    Secondary Accessions:
    • Q15255
    • Q6P4H4
    • Q8NHM2
    • Q9UDA9

    Protein attributes for PTPRJ Gene

    Size:
    1337 amino acids
    Molecular mass:
    145941 Da
    Quaternary structure:
    • Monomer. Interacts with CTNNB1 (phosphorylated) and JUP (phosphorylated). Interacts with FLT3 (phosphorylated). Interacts with GAB1 and GRB2.

    Three dimensional structures from OCA and Proteopedia for PTPRJ Gene

    Alternative splice isoforms for PTPRJ Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PTPRJ Gene

Selected DME Specific Peptides for PTPRJ Gene

Post-translational modifications for PTPRJ Gene

  • N- and O-glycosylated.
  • Glycosylation at Asn 72, Asn 82, Asn 93, Asn 104, Asn 142, Asn 172, Asn 192, Asn 231, Asn 258, Asn 278, Asn 342, Asn 351, Asn 376, Asn 391, Asn 396, Asn 413, Asn 431, Asn 501, Asn 525, Asn 536, Asn 582, Asn 603, Asn 618, Asn 628, Asn 637, Asn 666, Asn 669, Asn 761, Asn 772, Asn 784, Asn 790, Asn 824, Asn 910, and Asn 937
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cloud-Clone Corp. Antibodies for PTPRJ

Domains & Families for PTPRJ Gene

Suggested Antigen Peptide Sequences for PTPRJ Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q12913

UniProtKB/Swiss-Prot:

PTPRJ_HUMAN :
  • Contains 9 fibronectin type-III domains.
  • Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.
Domain:
  • Contains 9 fibronectin type-III domains.
  • Contains 1 tyrosine-protein phosphatase domain.
Family:
  • Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.
genes like me logo Genes that share domains with PTPRJ: view

Function for PTPRJ Gene

Molecular function for PTPRJ Gene

GENATLAS Biochemistry:
protein tyrosine kinase,receptor type,J polypeptide
UniProtKB/Swiss-Prot CatalyticActivity:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
UniProtKB/Swiss-Prot Function:
Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.

Enzyme Numbers (IUBMB) for PTPRJ Gene

Gene Ontology (GO) - Molecular Function for PTPRJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004721 phosphoprotein phosphatase activity IEA --
GO:0004725 protein tyrosine phosphatase activity IEA,TAS --
GO:0005161 platelet-derived growth factor receptor binding IPI 10821867
GO:0005515 protein binding IPI 10821867
GO:0008013 beta-catenin binding IPI 12370829
genes like me logo Genes that share ontologies with PTPRJ: view
genes like me logo Genes that share phenotypes with PTPRJ: view

Human Phenotype Ontology for PTPRJ Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for PTPRJ Gene

MGI Knock Outs for PTPRJ:

Animal Model Products

  • Taconic Biosciences Mouse Models for PTPRJ

Inhibitory RNA Products

Flow Cytometry Products

No data available for Transcription Factor Targets and HOMER Transcription for PTPRJ Gene

Localization for PTPRJ Gene

Subcellular locations from UniProtKB/Swiss-Prot for PTPRJ Gene

Cell membrane; Single-pass type I membrane protein. Cell projection, ruffle membrane. Cell junction. Note=After T-cell stimulation, it is temporarily excluded from immunological synapses.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PTPRJ Gene COMPARTMENTS Subcellular localization image for PTPRJ gene
Compartment Confidence
extracellular 5
plasma membrane 5
nucleus 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for PTPRJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001772 immunological synapse IDA 12913111
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS 7937872
GO:0005911 cell-cell junction IDA 12370829
GO:0009986 cell surface IDA 12913111
genes like me logo Genes that share ontologies with PTPRJ: view

Pathways & Interactions for PTPRJ Gene

genes like me logo Genes that share pathways with PTPRJ: view

Pathways by source for PTPRJ Gene

SIGNOR curated interactions for PTPRJ Gene

Gene Ontology (GO) - Biological Process for PTPRJ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006470 protein dephosphorylation IEA --
GO:0008285 negative regulation of cell proliferation IDA 14709717
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway IDA 14709717
GO:0016311 dephosphorylation IEA --
GO:0030155 regulation of cell adhesion IMP 12370829
genes like me logo Genes that share ontologies with PTPRJ: view

Drugs & Compounds for PTPRJ Gene

(6) Drugs for PTPRJ Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0

(2) Additional Compounds for PTPRJ Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Phosphate
  • NFB Orthophosphate
  • O-Phosphoric acid
  • Ortho-phosphate
  • Orthophosphate (PO43-)
  • Orthophosphate(3-)
14265-44-2
genes like me logo Genes that share compounds with PTPRJ: view

Transcripts for PTPRJ Gene

Unigene Clusters for PTPRJ Gene

Protein tyrosine phosphatase, receptor type, J:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PTPRJ Gene

No ASD Table

Relevant External Links for PTPRJ Gene

GeneLoc Exon Structure for
PTPRJ
ECgene alternative splicing isoforms for
PTPRJ

Expression for PTPRJ Gene

mRNA expression in normal human tissues for PTPRJ Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for PTPRJ Gene

This gene is overexpressed in Whole Blood (x9.3).

Protein differential expression in normal tissues from HIPED for PTPRJ Gene

This gene is overexpressed in Serum (15.2), Peripheral blood mononuclear cells (14.1), Neutrophil (11.5), and Nasal epithelium (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PTPRJ Gene



NURSA nuclear receptor signaling pathways regulating expression of PTPRJ Gene:

PTPRJ

SOURCE GeneReport for Unigene cluster for PTPRJ Gene:

Hs.318547

mRNA Expression by UniProt/SwissProt for PTPRJ Gene:

Q12913-PTPRJ_HUMAN
Tissue specificity: Expressed in the promyelocytic cell line HL-60, the granulocyte-macrophage colony-stimulating factor-dependent leukemic cell line F-36P, and the IL3 and erythropoietin-dependent leukemic cell line F-36E. Expressed predominantly in epithelial cells and lymphocytes. Enhanced expression at high cell density.
genes like me logo Genes that share expression patterns with PTPRJ: view

Primer Products

No data available for Protein tissue co-expression partners for PTPRJ Gene

Orthologs for PTPRJ Gene

This gene was present in the common ancestor of animals.

Orthologs for PTPRJ Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PTPRJ 34 35
  • 99.32 (n)
dog
(Canis familiaris)
Mammalia PTPRJ 34 35
  • 79.56 (n)
cow
(Bos Taurus)
Mammalia PTPRJ 34 35
  • 78.67 (n)
mouse
(Mus musculus)
Mammalia Ptprj 34 16 35
  • 77.71 (n)
rat
(Rattus norvegicus)
Mammalia Ptprj 34
  • 77.48 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia PTPRJ 35
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia PTPRJ 35
  • 54 (a)
OneToOne
chicken
(Gallus gallus)
Aves PTPRJ 34 35
  • 56.22 (n)
lizard
(Anolis carolinensis)
Reptilia PTPRJ 35
  • 42 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ptprjb 35
  • 62 (a)
OneToMany
ptprja 34 35
  • 49.65 (n)
PTPRJ (2 of 3) 35
  • 25 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Ptp52F 36 35
  • 38 (a)
worm
(Caenorhabditis elegans)
Secernentea F36H1.3 36
  • 36 (a)
F47B3.1 36
  • 35 (a)
F47B3.6 36
  • 35 (a)
Y48G9A.9 36
  • 33 (a)
T22C1.8 36
  • 32 (a)
ZK354.8 36
  • 32 (a)
Y71G12B.31 35
  • 30 (a)
OneToMany
Y41D4A.5 36
  • 29 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 30 (a)
ManyToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.3156 34
Species where no ortholog for PTPRJ was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for PTPRJ Gene

ENSEMBL:
Gene Tree for PTPRJ (if available)
TreeFam:
Gene Tree for PTPRJ (if available)

Paralogs for PTPRJ Gene

Paralogs for PTPRJ Gene

Pseudogenes.org Pseudogenes for PTPRJ Gene

genes like me logo Genes that share paralogs with PTPRJ: view

Variants for PTPRJ Gene

Sequence variations from dbSNP and Humsavar for PTPRJ Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs121434507 A colon cancer sample, Pathogenic 48,123,636(+) ATCTC(C/T)GTGTT nc-transcript-variant, reference, missense
rs1566734 Pathogenic, A colon cancer sample 48,123,823(-) TTGAT(G/T)GTAGA nc-transcript-variant, reference, missense
rs61739179 Likely benign 48,127,939(+) GCCTC(A/G)CGCTG nc-transcript-variant, reference, missense
rs1018137 -- 48,149,673(-) AGCCA(A/G)CTTCA intron-variant
rs10219290 -- 48,085,210(+) CTAAG(C/G)AGACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PTPRJ Gene

Variant ID Type Subtype PubMed ID
dgv1111n100 CNV gain 25217958
dgv1112n100 CNV gain 25217958
dgv198e214 CNV gain 21293372
dgv635n106 CNV deletion 24896259
esv1002186 CNV deletion 20482838
esv2380235 CNV deletion 18987734
esv2458591 CNV deletion 19546169
esv2657950 CNV deletion 23128226
esv2674478 CNV deletion 23128226
esv2744445 CNV deletion 23290073
esv3256940 CNV deletion 24192839
esv3499 CNV loss 18987735
esv3547717 CNV deletion 23714750
esv3626221 CNV loss 21293372
esv3626222 CNV loss 21293372
esv3626223 CNV loss 21293372
esv3626224 CNV gain 21293372
esv3626225 CNV loss 21293372
esv3626226 CNV gain 21293372
esv3626227 CNV loss 21293372
esv3891981 CNV loss 25118596
esv3891986 CNV gain 25118596
esv7637 CNV loss 19470904
esv990562 CNV deletion 20482838
nsv1041394 CNV gain 25217958
nsv1053145 CNV gain 25217958
nsv1053528 CNV loss 25217958
nsv1069580 CNV deletion 25765185
nsv1070956 CNV deletion 25765185
nsv317 CNV deletion 18451855
nsv39746 CNV deletion 16902084
nsv428253 CNV loss 18775914
nsv467871 CNV gain 19166990
nsv528641 CNV loss 19592680
nsv554211 CNV gain 21841781

Variation tolerance for PTPRJ Gene

Residual Variation Intolerance Score: 62.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.82; 67.02% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PTPRJ Gene

Human Gene Mutation Database (HGMD)
PTPRJ
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PTPRJ

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PTPRJ Gene

Disorders for PTPRJ Gene

MalaCards: The human disease database

(10) MalaCards diseases for PTPRJ Gene - From: OMIM, ClinVar, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
colorectal cancer
  • colorectal cancer, somatic
precursor b lymphoblastic lymphoma/leukemia
  • b lymphoblastic leukemia/lymphoma
precursor lymphoblastic lymphoma/leukemia
  • precursor lymphoid neoplasm
cogan syndrome
  • cogan's syndrome
deep keratitis
- elite association - COSMIC cancer census association via MalaCards
Search PTPRJ in MalaCards View complete list of genes associated with diseases

Relevant External Links for PTPRJ

Genetic Association Database (GAD)
PTPRJ
Human Genome Epidemiology (HuGE) Navigator
PTPRJ
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PTPRJ
genes like me logo Genes that share disorders with PTPRJ: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PTPRJ Gene

Publications for PTPRJ Gene

  1. The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis. (PMID: 15378013) Iuliano R. … Fusco A. (Oncogene 2004) 3 4 22 46 64
  2. Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. (PMID: 7937872) Oestman A. … Tonks N.K. (Proc. Natl. Acad. Sci. U.S.A. 1994) 2 3 4 22 64
  3. Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta. (PMID: 7994032) Honda H. … Hirai H. (Blood 1994) 2 3 4 22 64
  4. Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells. (PMID: 19922411) Omerovic J. … Prior I.A. (Biochem. J. 2010) 3 4 22 64
  5. Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers. (PMID: 19672627) Mita Y. … Shimizu K. (J. Cancer Res. Clin. Oncol. 2010) 3 22 46 64

Products for PTPRJ Gene

Sources for PTPRJ Gene

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