Aliases for PTPN4 Gene
External Ids for PTPN4 Gene
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]
GeneCards Summary for PTPN4 Gene
PTPN4 (Protein Tyrosine Phosphatase, Non-Receptor Type 4 (Megakaryocyte)) is a Protein Coding gene. Among its related pathways are PAK Pathway. GO annotations related to this gene include cytoskeletal protein binding and non-membrane spanning protein tyrosine phosphatase activity. An important paralog of this gene is FRMD3.
UniProtKB/Swiss-Prot for PTPN4 Gene
May act at junctions between the membrane and the cytoskeleton