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PTPN20A Gene

protein-coding   GIFtS: 39
GCID: GC10M046550

Protein Tyrosine Phosphatase, Non-Receptor Type 20A

  Search for PTPN20A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Protein Tyrosine Phosphatase, Non-Receptor Type 20A1 2     CT1262
Cancer/Testis Antigen 1261 2     PTPN20B2
hPTPN202 3     bA142I17.12
EC 3.1.3.483 8     Tyrosine-Protein Phosphatase Non-Receptor Type 202

External Ids:    HGNC: 234221   Entrez Gene: 6531292   Ensembl: ENSG000002041797   OMIM: 6106305   UniProtKB: Q4JDL33   

Export aliases for PTPN20A gene to outside databases

Previous GC identifers: GC10U900462 GC10M045970 GC10M043492


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PTPN20A Gene:
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many
protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated
in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein
tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and
PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene
encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different
isoforms have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for PTPN20A Gene:
PTPN20A (protein tyrosine phosphatase, non-receptor type 20A) is a protein-coding gene. GO annotations related to this gene include protein tyrosine phosphatase activity. An important paralog of this gene is PTPN1.

UniProtKB/Swiss-Prot: PTN20_HUMAN, Q4JDL3
Function: Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied
extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PTPN20A gene promoter:
         MEF-2A   GR   AML1a   FOXC1   MEF-2   aMEF-2   GR-alpha   FOXL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPTPN20A promoter sequence
   Search Chromatin IP Primers for PTPN20A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PTPN20A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.22   Ensembl cytogenetic band:  10q11.22   HGNC cytogenetic band: 10q11.22

PTPN20A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PTPN20A gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M046550:  view genomic region     (about GC identifiers)

Start:
46,549,955 bp from pter      End:
46,641,045 bp from pter
Size:
91,091 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PTN20_HUMAN, Q4JDL3 (See protein sequence)
Recommended Name: Tyrosine-protein phosphatase non-receptor type 20  
Size: 420 amino acids; 48423 Da
Sequence caution: Sequence=AAW28797.1; Type=Erroneous translation; Note=Wrong choice of frame;
Secondary accessions: A6NNH8 B7ZKV3 Q4JDG6 Q4JDK1 Q4JDK5 Q4JDK6 Q4JDK8 Q4JDK9 Q4JDL0 Q4JDL1
Q4JDL4 Q4JDL5 Q4JDL6 Q4JDL7 Q4JDL8 Q5RJ33 Q5T1G3
Alternative splicing: 15 isoforms:  Q4JDL3-1   Q4JDL3-2   Q4JDL3-3   Q4JDL3-4   Q4JDL3-5   Q4JDL3-6   Q4JDL3-7   Q4JDL3-8   
Q4JDL3-9   Q4JDL3-10   Q4JDL3-11   Q4JDL3-12   Q4JDL3-13   Q4JDL3-14   Q4JDL3-15   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for PTPN20A: NX_Q4JDL3

Explore proteomics data for PTPN20A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for PTPN20A (Q4JDL3)
     VVHCSAG  YIATQGP  QRSGMVQT  HCSAGIGR 


    See PTPN20A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (10 alternative transcripts): 
    NP_001035846.1  NP_001035848.1  NP_001035849.1  NP_001035850.1  NP_001035851.1  NP_001035852.1  NP_001035853.1  NP_001035854.1  
    NP_001035855.1  NP_001035856.1  

    ENSEMBL proteins: 
     ENSP00000379071   ENSP00000363466   ENSP00000424491   ENSP00000363459   ENSP00000379077  
     ENSP00000423819   ENSP00000427676   ENSP00000421921   ENSP00000422839   ENSP00000420995  
     ENSP00000426355   ENSP00000425362   ENSP00000424283   ENSP00000425012   ENSP00000421453  
     ENSP00000425912   ENSP00000421404   ENSP00000396009   ENSP00000426681   ENSP00000422384  
     ENSP00000403444   ENSP00000363462   ENSP00000379072   ENSP00000363335   ENSP00000379075  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PTPN: Protein tyrosine phosphatases / Class I Cys-based PTPs : Non-receptor

    3 InterPro protein domains:
     IPR016130 Tyr_Pase_AS
     IPR000242 Tyr_Pase_rcpt/non-rcpt
     IPR000387 Tyr/Dual-sp_Pase

    Graphical View of Domain Structure for InterPro Entry Q4JDL3

    ProtoNet protein and cluster: Q4JDL3

    1 Blocks protein domain: IPB000242 Protein tyrosine phosphatase signature

    UniProtKB/Swiss-Prot: PTN20_HUMAN, Q4JDL3
    Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily
    Similarity: Contains 1 tyrosine-protein phosphatase domain


    PTPN20A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PTN20_HUMAN, Q4JDL3
    Function: Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied
    extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates
    Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate

         Enzyme Number (IUBMB): EC 3.1.3.481 2

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004725protein tyrosine phosphatase activity IEA--
    GO:0016791phosphatase activity ----
         
    PTPN20A for ontologies           About GeneDecksing


    Animal Models:
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    hsa-miR-3163 hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-4272 hsa-miR-1258 hsa-miR-944 hsa-miR-138-2* hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidPTPN20A 3' UTR sequence
    Inhib. RNA
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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PTN20_HUMAN, Q4JDL3: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
    Note=Colocalizes with the microtubule-organizing center and intracellular membrane compartments
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus5
    cytosol3
    extracellular1
    golgi apparatus1
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0005815microtubule organizing center IEA--
    GO:0005874microtubule IEA--

    PTPN20A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PTPN20A About    
    See pathways by source

    SuperPathContained pathways About
    1PAK Pathway
    Epithelial Adherens Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for PTPN20A
        Epithelial Adherens Junctions


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PTPN20A
    Interactions:

        Search GeneGlobe Interaction Network for PTPN20A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for PTPN20A (ENSP000003634594) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP3K4ENSP000003759864STRING: ENSP00000375986
    PKMYT1ENSP000002623004STRING: ENSP00000262300
    WEE1ENSP000004020844STRING: ENSP00000402084
    WEE2ENSP000003806754STRING: ENSP00000380675
    MAP2K1ENSP000003024864STRING: ENSP00000302486
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006470protein dephosphorylation ----
    GO:0016311dephosphorylation ----

    PTPN20A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PTPN20A (PTN20)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PTPN20A gene (10 alternative transcripts): 
    NM_001042387.1  NM_001042389.1  NM_001042390.1  NM_001042391.1  NM_001042392.1  NM_001042393.1  NM_001042394.1  NM_001042395.1  
    NM_001042396.1  NM_001042397.1  

    Unigene Cluster for PTPN20A:

    Protein tyrosine phosphatase, non-receptor type 20A
    Hs.440733  [show with all ESTs]
    Unigene Representative Sequence: NM_001042389
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 32):
    ENST00000374340(uc001jdk.1) ENST00000395721(uc001jde.1 uc001jdg.1 uc009xmw.1 uc001jdp.1)
    ENST00000246887(uc001jdl.1 uc001jdq.1) ENST00000509181(uc001jdu.1)
    ENST00000374346(uc001jcz.1 uc001jdh.1 uc001jdm.1 uc001jdt.1)
    ENST00000508602 ENST00000374339 ENST00000395727 ENST00000509900 ENST00000503851
    ENST00000506080 ENST00000513266 ENST00000502705 ENST00000505814 ENST00000509774
    ENST00000511769 ENST00000513159 ENST00000509599
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate PTPN20A (see all 14):
    hsa-miR-3163 hsa-miR-3152-3p hsa-miR-3607-3p hsa-miR-4272 hsa-miR-1258 hsa-miR-944 hsa-miR-138-2* hsa-miR-3133
    SwitchGear 3'UTR luciferase reporter plasmidPTPN20A 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat PTPN20A

    17 DOTS entries:

    DT.40297888  DT.100745172  DT.121288848  DT.121285645  DT.121285666  DT.121288849  DT.121288957  DT.121289024 
    DT.121289173  DT.99940484  DT.121285649  DT.121285655  DT.121285661  DT.121288951  DT.121289019  DT.121289039 
    DT.95261537 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PTPN20A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    PTPN20A Expression
    About this image

    PTPN20A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PTPN20A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.440733

    UniProtKB/Swiss-Prot: PTN20_HUMAN, Q4JDL3
    Tissue specificity: Present in many cell lines (at protein level). Widely expressed

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PTPN20A gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    15(a)
    1 → many
    6(17703944-17731676)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    48(a)
    1 → many
    GL343297.1(547889-583831)
    zebrafish
    (Danio rerio)
    Actinopterygii ptpn11b6
    protein tyrosine phosphatase, non-receptor type 11...
    20(a)
    many ↔ many
    23(24205304-24282739) ENSDARG00000012340
    worm
    (Caenorhabditis elegans)
    Secernentea K07F5.86
    F47B3.76
    (see all 23)
    Protein F47B3.7 (F47B3.7) mRNA, complete cds
    (see all 23)
    25(a)
    23(a)
    (see all 23)
    many ↔ many
    many ↔ many
    (see all 23)
    IV(9848483-9849724) WBGene00010636
    I(3968164-3970012) WBGene00018531
            Species with no ortholog for PTPN20A

    ENSEMBL Gene Tree for PTPN20A (if available)
    TreeFam Gene Tree for PTPN20A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PTPN20A gene
    PTPN12  PTPN222  PTPN112  PTPN92  PTPN62  PTPRN22  PTPRN2  PTPN142  
    PTPN212  PTPN20B2  PTPN22  PTPN122  PTPN182  
    Selected SIMAP similar genes for PTPN20A using alignment to 6 protein entries:     PTN20_HUMAN (see all proteins) (see all similar genes):
    DKFZp781P23155    PTPN20    PTPN20B    DKFZp566K0524    DKFZp781C1038    PTPRR
    DKFZp686B1310    LAR    PTPRF    PTPsigma    PTN2    PTPN13
    PTPN2    PTPRD    PTPRS    DKFZp686E13109    PTPRB    BPTP-2

    PTPN20A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PTPN20A (see all 83)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2010851751,2
    C--46553115(+) CAACTG/TAACAG 10 -- int10--------
    rs2022184981,2
    C--46553122(+) ACAGGA/TTATAG 10 -- int10--------
    rs2021988051,2
    C--46553823(+) TGTGT-/GAGAGTG 10 -- int10--------
    rs2020329711,2
    C--46556919(+) CCACAC/TTGCAG 10 -- int10--------
    rs1882088121,2
    --46562102(+) TTGAGA/TTGGAG 10 -- int10--------
    rs2007389701,2
    C--46562269(+) AGAGAC/TGGGGT 10 -- int10--------
    rs2017277981,2
    C--46562336(+) TCGGCC/TTCCCA 10 -- int10--------
    rs1932764051,2
    C--46562878(+) ATCCCC/TGATGA 10 -- int10--------
    rs2004669841,2
    C--46568800(+) AGGAC-/ATGTTAT 10 -- int10--------
    rs1389057681,2
    C--46578019(+) ATGAGC/TGGAGG 10 -- int10--------

    HapMap Linkage Disequilibrium report for PTPN20A (46549955 - 46641045 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PTPN20A (see all 39):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv820767CNV Deletion20802225
    nsv436102CNV Deletion17901297
    esv2736163CNV Deletion23290073
    nsv820873CNV Deletion20802225
    dgv136e199CNV Deletion23128226
    nsv895348CNV Loss21882294
    nsv433259CNV Loss18776910
    nsv895344CNV Loss21882294
    esv2750898CNV Loss17911159
    nsv895117CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610630    OMIM disorders: --


    PTPN20A for disorders           About GeneDecksing


    Export disorders for PTPN20A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PTPN20A gene integrated from 10 sources:
    (articles sorted by number of sources associating them with PTPN20A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization. (PubMed id 15790311)1, 2 Fodero-Tavoletti M.T.... Tiganis T. (Biochem. J. 2005)
    2. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    3. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (Nature 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 653129 HGNC: 23422 Ensembl:ENSG00000204179 euGenes: HUgn653129 ECgene: PTPN20A
    H-InvDB: PTPN20A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PTPN20A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PTPN20A gene:
    Search GeneIP for patents involving PTPN20A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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