Aliases for PTPN20 Gene
External Ids for PTPN20 Gene
Previous HGNC Symbols for PTPN20 Gene
Previous GeneCards Identifiers for PTPN20 Gene
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
GeneCards Summary for PTPN20 Gene
PTPN20 (Protein Tyrosine Phosphatase, Non-Receptor Type 20) is a Protein Coding gene. Among its related pathways are PAK Pathway. GO annotations related to this gene include phosphatase activity and protein tyrosine phosphatase activity. An important paralog of this gene is PTPN14.
UniProtKB/Swiss-Prot for PTPN20 Gene
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.