PTPN18 Gene
protein-coding GIFtS: 63
GCID: GC02P131113
|
|
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
| |
Aliases
for PTPN18 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Protein Tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived)1 2 | | BDP11 2 3 5 | | Brain-Derived Phosphatase2 3 | | EC 3.1.3.483 8 | | PTP-HSCF2 | | Tyrosine-Protein Phosphatase Non-Receptor Type 182 |
Export aliases for PTPN18 gene to outside databasesPrevious GC identifers: GC02M128348 GC02M129897 GC02P131018 GC02P131206 GC02P130829 GC02P123403 |
Summaries
for PTPN18 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PTPN18:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitoticcycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-proteininteraction domain, and may be related to protein intracellular half-live. This protein can differentiallydephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears toregulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcriptvariants encoding different isoforms have been found for this gene. (provided by RefSeq, Nov 2008)
UniProtKB/Swiss-Prot: PTN18_HUMAN, Q99952Function: Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed intumor tissues
Gene Wiki entry for PTPN18
|
Genomic Views
for PTPN18 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022135.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PTPN18 gene promoter:
SRF MAZR SRF (504 AA) MyoD MIF-1 CREB PPAR-alpha deltaCREB Pax-4a ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for PTPN18
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PTPN18 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q21.1 Ensembl cytogenetic band: 2q21.1 HGNC cytogenetic band: 2q21PTPN18 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P131113: view genomic region
(about GC identifiers)
Start:
|
131,113,580 bp from pter |
End:
|
131,132,982 bp from pter |
Size:
|
19,403 bases |
Orientation:
|
plus strand |
|
Proteins
for PTPN18 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PTN18_HUMAN, Q99952 (See
protein sequence)Recommended Name: Tyrosine-protein phosphatase non-receptor type 18 Size: 460 amino acids; 50482 Da
Subunit: Interacts with PSTPIP1 (By similarity)
Subcellular location: Nucleus (By similarity). Cytoplasm (By similarity)
1 PDB 3D structure from  and Proteopedia  for PTPN18:2OC3 (3D)
Secondary accessions: B4E1E6 Q53P42Alternative splicing: 2 isoforms: Q99952-1 Q99952-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for PTPN18: NX_Q99952
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99952
2 DME Specific Peptides for PTPN18 (Q99952)
PTPN18 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001135842.1 NP_055184.2
ENSEMBL proteins: ENSP00000175756 ENSP00000310092 ENSP00000411750 ENSP00000387031
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
PTPN18 for ontologies About GeneDecksing
PTPN18 Antibody Products:
Assay Products for PTPN18: |
Protein
Domains /
Families
for PTPN18 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PTPN18 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99952ProtoNet protein and cluster: Q99952 1 Blocks protein family: IPB000242 Protein tyrosine phosphatase signature
UniProtKB/Swiss-Prot: PTN18_HUMAN, Q99952Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamilySimilarity: Contains 1 tyrosine-protein phosphatase domain |
Function
for PTPN18 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PTN18_HUMAN, Q99952Function: Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed intumor tissuesCatalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate Genatlas biochemistry entry for PTPN18:protein tyrosine phosphatase,non-receptor type 18,expressed in brain,colon and several tumor-derived cell lines
Enzyme Number (IUBMB): EC 3.1.3.481 2
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PTPN18 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for PTPN18 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PTPN18 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PTPN18 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004725 | protein tyrosine phosphatase activity |
-- | -- | | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity |
IEA | -- | | GO:0005515 | protein binding |
-- | -- |
PTPN18 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for PTPN18:
|
Pathways & Interactions
for PTPN18 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Protein Stability | | | 2 | B Cell Receptor Signaling Pathway | | | 3 | Phosphatases | | | 4 | PAK Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for PTPN18
2 
Cell Signaling Technology (CST) Pathways for PTPN18
1  BioSystems Pathway for PTPN18
PTPN18 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PTPN18
STRING Interaction
Network Preview (showing 5 interactants - click image to see 14)
5/14 Interacting proteins for PTPN18 (Q999522, 3 ENSP000001757564) via UniProtKB, MINT, STRING, and/or I2D (see all 14)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006470 | protein dephosphorylation |
TAS | 8950995 |
PTPN18 for ontologies About GeneDecksing
|
Drugs & Compounds
for PTPN18 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PTPN18
2 HMDB Compounds for PTPN18 About this table
Search CenterWatch for drugs/clinical trials and news about PTPN18 / PTN18
|
Transcripts
for PTPN18 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PTPN18 gene (2 alternative transcripts): NM_001142370.1 NM_014369.3 Unigene Cluster for PTPN18: Protein tyrosine phosphatase, non-receptor type 18 (brain-derived) Hs.516390 [show with all ESTs]Unigene Representative Sequence: NM_01436916 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000175756(uc002trc.3 uc002trb.3 uc002tre.3) ENST00000347849
ENST00000489215 ENST00000428843 ENST00000409022 ENST00000420717 ENST00000483617
ENST00000479295 ENST00000460992 ENST00000495400 ENST00000490812 ENST00000462996
ENST00000464576 ENST00000490137 ENST00000481492 ENST00000462321
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PTPN18 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PTPN18 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): PTPN18 (NM_001142370) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PTPN18 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PTPN18 |
Additional cDNA sequence: AK297884.1 AK303804.1 BC024280.1 BC041562.1 BC052800.1 X79568.1 24/27 DOTS entries (see all 27): DT.415969 DT.100751707 DT.92455428 DT.97859241 DT.100775592 DT.92455407 DT.120981520 DT.91875410 DT.429645 DT.95313577 DT.306615 DT.95306663 DT.100746051 DT.91700098 DT.91860968 DT.92455403 DT.95306684 DT.95343851 DT.120980897 DT.120981444 DT.100733576 DT.121610570 DT.40282072 DT.86853207 24/284 AceView cDNA sequences (see all 284): AA568882 BM724913 BQ436608 BX107629 AA524210 BM695240 CD672484 BE271713 CD672483 AA702095 BM711510 BQ102255 BE327745 BQ086140 BU537921 AW204520 BU619831 AA809133 BM789073 AA235326 AW575379 CA427181 CR608379 AI910153
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for PTPN18 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | · | 14d | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | |
| ExUns: | 17 |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for PTPN18
|
Expression
for PTPN18 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PTPN18 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAAAGTGAC
About this image
See PTPN18 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PTPN18
SOURCE GeneReport for Unigene cluster: Hs.516390
UniProtKB/Swiss-Prot: PTN18_HUMAN, Q99952Tissue specificity: Expressed in brain, colon and several tumor-derived cell lines
SABiosciences Custom PCR Arrays for PTPN18
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PTPN18
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PTPN18 |
Orthologs
for PTPN18 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for PTPN18 gene from 3/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
ptpn181 |
protein tyrosine phosphatase, non-receptor type 18 |
52.03(n)
45.5(a) |
|
541324 NM_001013452.1 NP_001013470.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATPTP16 |
tyrosine phosphatase 1 |
24(a) |
1 → many |
1(27026711-27029092) |
rice
(Oryza sativa) |
Liliopsida |
---- |
Protein-tyrosine phosphatase domain containing pro...Protein-tyrosine phosphatase domain containing pro... |
25(a)22(a) |
many ↔ manymany ↔ many |
12(3791109-3796496) 11(4000708-4008336) |
ENSEMBL Gene Tree for PTPN18 (if available)
TreeFam Gene Tree for PTPN18 (if available) |
Paralogs
for PTPN18 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PTPN18 gene
- PTPN72 PTPRH2 PTPN222 PTPRO2 PTPN112 PTPN62 PTPRJ2 PTPRQ2
- PTPN122 PTPN52 PTPRB2 PTPRR2
14 SIMAP similar genes for PTPN18 using alignment to 3 protein entries: PTN18_HUMAN (see all proteins):BPTP-3 PTP PTPN22 PTPN12 PTPRR PTPRH
DKFZp566K0524 DKFZp781C1038 PTPN20A PTPN7 PTPN5 PTPN3
PTPN4 DKFZp761A0712
PTPN18 for paralogs About GeneDecksing
|
Genomic Variants
for PTPN18 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PTPN18 (131113580 - 131132982 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for PTPN18
4 CNVs: 3393 53632 2408 8387 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PTPN18 |
|
Disorders
/ Diseases
for PTPN18 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PTPN18 for disorders About GeneDecksing
OMIM gene information: 606587
OMIM disorders: --
3  diseases for PTPN18: About MalaCardspyoderma gangrenosum pyoderma papa syndrome
1 disease from the University of Copenhagen DISEASES database for PTPN18:Pyoderma gangrenosum Export disorders for PTPN18 gene to outside databases
|
Publications
for PTPN18 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PTPN18 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with PTPN18) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the PEST family protein tyrosine phosphatase BDP1. (PubMed id 8950995)1, 2, 3, 9 Kim Y.W.... Ullrich A. (1996)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- Large-scale structural analysis of the classical human protein tyrosine phosphatome. (PubMed id 19167335)2 Barr A.J.... Knapp S. (2009)
- Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. (PubMed id 15951569)1 Zhang Y.... White F.M. (2005)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. (PubMed id 16094384)1 Tao W.A.... Aebersold R. (2005)
- Substrate-trapping techniques in the identification of cellular PTP targets. (PubMed id 15588985)1 Blanchetot C....Tremblay M.L. (2005)
- A bioinformatics analysis of protein tyrosine phosphatases in humans. (PubMed id 16303740)1 Gandhi T.K....Pandey A. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for PTPN18 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PTPN18 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PTPN18 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PTPN18 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for PTPN18 gene:
Search GeneIP for patents involving PTPN18
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PTPN18 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PTPN18 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PTPN18 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PTPN18 | | | OriGene Protein Over-expression Lysate for PTPN18 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PTPN18 | | OriGene 3'-UTR Clone for PTPN18 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PTPN18 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PTPN18 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PTPN18 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PTPN18 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PTPN18 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PTPN18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PTPN18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PTPN18 |
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| | Antibodies & Assays for PTPN18 (BDP1) |
| | | | Search Tocris compounds for PTPN18 |
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 | | | PTPN18 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PTPN18 |
|  |  |  | | | | ThermoFisher Antibodies for PTPN18 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PTPN18 |
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