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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PTPLAD1 Gene

protein-coding   GIFtS: 49
GCID: GC15P065822

protein tyrosine phosphatase-like A domain containing 1
 Explore 2 diseases affiliated with
PTPLAD1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for PTPLAD1    

Aliases
for PTPLAD1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Protein Tyrosine Phosphatase-Like A Domain Containing 11 2     HACD32 3
HSPC1211 2     HB-Ind11
B-Ind11     B-IND12
Butyrate-Induced Protein 12 3     Butyrate-Induced Transcript 12
Protein Tyrosine Phosphatase-Like Protein PTPLAD12 3     BIND13
Protein-Tyrosine Phosphatase-Like A Domain-Containing Protein 12 3     EC 4.2.1.1343
3-Hydroxyacyl-CoA Dehydratase 32 3     

External Ids:    HGNC: 241751   Entrez Gene: 514952   Ensembl: ENSG000000746967   UniProtKB: Q9P0353   

Export aliases for PTPLAD1 gene to outside databases

Previous GC identifers: GC15P063610 GC15P042647


Summaries
for PTPLAD1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: HACD3_HUMAN, Q9P035
Function: Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis. Involved in
Rac1-signaling pathways leading to the modulation of gene expression

Gene Wiki entry for PTPLAD1


Genomic Views
for PTPLAD1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.1  NT_010194.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PTPLAD1 gene promoter:
         USF1   AML1a   USF-1   FOXO1a   AP-4   HNF-3beta   E47   GATA-1   GATA-2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PTPLAD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PTPLAD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PTPLAD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22.2   Ensembl cytogenetic band:  15q22.31   HGNC cytogenetic band: 15q22.2

PTPLAD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PTPLAD1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P065822:  view genomic region     (about GC identifiers)

Start:
 65,822,756 bp from pter      End:
 65,870,693 bp from pter
Size:
 47,938 bases      Orientation:
 plus strand

Proteins
for PTPLAD1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: HACD3_HUMAN, Q9P035 (See protein sequence)
Recommended Name: Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 3  
Size: 362 amino acids; 43160 Da
Subunit: Interacts with the condensation enzymes of the ELOVL family. Interacts with RAC1
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAF29085.1; Type=Frameshift; Positions=356; Sequence=BAC11249.1; Type=Frameshift;
Positions=359;
Secondary accessions: A0PJA1 Q280Z3 Q6PD63 Q8IUI5 Q8NC86 Q8NCB1 Q96T12 Q9NQA7

Explore the universe of human proteins at neXtProt for PTPLAD1: NX_Q9P035

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9P035

    • PTPLAD1 Protein expression data from MOPED and PaxDb:    About this image 
    PTPLAD1 Protein Expression
    REFSEQ proteins: NP_057479.2  
    ENSEMBL proteins: 
     ENSP00000455686   ENSP00000261875   ENSP00000392491   ENSP00000456568   ENSP00000455530  
     ENSP00000456300   ENSP00000455587   ENSP00000454873   ENSP00000454610  

    Human Recombinant Protein Products for PTPLAD1: 
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    Novus Biologicals PTPLAD1 Proteins
    Novus Biologicals PTPLAD1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PTPLAD1

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral to membrane IEA--

    PTPLAD1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for PTPLAD1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PTPLAD1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR007482 Tyr_Pase-like_PTPLA
     IPR008978 HSP20-like_chaperone
     IPR017447 CS_domain
     IPR007052 CS-like_domain

    Graphical View of Domain Structure for InterPro Entry Q9P035

    ProtoNet protein and cluster: Q9P035

    UniProtKB/Swiss-Prot: HACD3_HUMAN, Q9P035
    Similarity: Belongs to the very long-chain fatty acids dehydratase HACD family
    Similarity: Contains 1 CS domain


    Function
    for PTPLAD1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: HACD3_HUMAN, Q9P035
    Function: Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis. Involved in
    Rac1-signaling pathways leading to the modulation of gene expression
    Catalytic activity: A very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] = a very-long-chain
    trans-2,3-dehydroacyl-[acyl-carrier protein] + H(2)O
    Induction: By AKAP12 and histone deacetylase inhibitors such as sodium butyrate

         Enzyme Number (IUBMB): EC 4.2.1.1341

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005096GTPase activator activity TAS10747961
    GO:0016829lyase activity IEA--
         
    PTPLAD1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Ptplad1 (no phenotypes)

    PTPLAD1 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Ptplad1tm1Lex for PTPLAD1
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for PTPLAD1 

    miRNA
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    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate PTPLAD1 (see all 41):
    hsa-miR-4307 hsa-miR-371-5p hsa-miR-508-3p hsa-miR-890 hsa-miR-4330 hsa-miR-34b hsa-miR-509-3-5p hsa-miR-548am
    SwitchGear 3'UTR luciferase reporter plasmid: PTPLAD1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for PTPLAD1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PTPLAD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/31 Interacting proteins for PTPLAD1 (Q9P0352, 3 ENSP000002618754) via UniProtKB, MINT, STRING, and/or I2D (see all 31)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFRSF1BP203332, 3MINT-49381 I2D: score=2 
    C20orf24Q9BUV83, ENSP000003412134I2D: score=2 STRING: ENSP00000341213
    NEK6Q9HC983, ENSP000003627024I2D: score=2 STRING: ENSP00000362702
    PELOQ9BRX23, ENSP000002743114I2D: score=2 STRING: ENSP00000274311
    SERINC3Q135303, ENSP000002551754I2D: score=2 STRING: ENSP00000255175
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006633fatty acid biosynthetic process IEA--
    GO:0007249I-kappaB kinase/NF-kappaB cascade IEA--
    GO:0007254JNK cascade ----
    GO:0007257activation of JUN kinase activity TAS10747961
    GO:0007264small GTPase mediated signal transduction TAS10747961

    PTPLAD1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for PTPLAD1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for PTPLAD1

    1 HMDB Compound for PTPLAD1    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--
    Search CenterWatch for drugs/clinical trials and news about PTPLAD1 / HACD3 

    Transcripts
    for PTPLAD1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PTPLAD1 gene: 
    NM_016395.2  

    Unigene Cluster for PTPLAD1:

    Protein tyrosine phosphatase-like A domain containing 1
    Hs.512973  [show with all ESTs]
    Unigene Representative Sequence: AK074898
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000562901 ENST00000261875(uc002apc.3 uc010uiw.2) ENST00000442729
    ENST00000565299 ENST00000568793 ENST00000566239 ENST00000566074 ENST00000566511
    ENST00000569894 ENST00000562832 ENST00000561998 ENST00000561763

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PTPLAD1
    8/41 QIAGEN miScript miRNA Assays for microRNAs that regulate PTPLAD1 (see all 41):
    hsa-miR-4307 hsa-miR-371-5p hsa-miR-508-3p hsa-miR-890 hsa-miR-4330 hsa-miR-34b hsa-miR-509-3-5p hsa-miR-548am
    SwitchGear 3'UTR luciferase reporter plasmid: PTPLAD1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PTPLAD1 (see all 7)
    OriGene shRNA RFP: PTPLAD1
    OriGene siRNA: PTPLAD1
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    Clone
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    Additional cDNA sequence: 

    AF161470.1 AJ271091.1 AK027421.1 AK074857.1 AK074898.1 AK225120.1 AK299234.1 AL137412.1 
    BC000194.1 BC009056.1 BC011443.1 BC019873.1 BC035508.1 BC047685.1 BC058912.1 

    20 DOTS entries:

    DT.100660924  DT.100730204  DT.85101739  DT.121039503  DT.121039479  DT.121039384  DT.100660927  DT.100660921 
    DT.100660929  DT.121039454  DT.95083722  DT.100660920  DT.121039431  DT.121039490  DT.92072276  DT.92072286 
    DT.99989277  DT.100637847  DT.121039508  DT.95178571 

    24/498 AceView cDNA sequences (see all 498):

    BM719201 BC058912 AI002456 AW305068 BF968596 BC009056 BE252690 AI016037 
    BE785710 BM142094 AA149624 AA937287 BU159260 BM450668 AI695422 CB158158 
    BM798856 AW592580 AI337609 BQ437552 BM985100 N63051 AI922565 AA883791 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for PTPLAD1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c ^ 13 ^ 14a · 14b ^ 15 ^ 16
    SP1:                                -     -     -     -     -                                                                                       
    SP2:                                                                                                                                                
    SP3:                                      -     -     -     -                                                                                       
    SP4:                          -     -     -     -     -     -                                                                                       
    SP5:                                -     -     -     -     -                             -     -                                                   


    ECgene alternative splicing isoforms for PTPLAD1

    Expression
    for PTPLAD1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PTPLAD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTGTAACAC
    PTPLAD1 Expression
    About this image
    See PTPLAD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PTPLAD1

    SOURCE GeneReport for Unigene cluster: Hs.512973

    UniProtKB/Swiss-Prot: HACD3_HUMAN, Q9P035
    Tissue specificity: Highly expressed in testis, kidney, brain, liver and weakly in skeletal muscle, spleen and heart.
    No expression detected in leukocytes

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    In Situ
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    Orthologs
    for PTPLAD1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PTPLAD1 gene from 7/27 species (see all 27)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves PTPLAD11 protein tyrosine phosphatase-like A domain containing more 71.82(n)
    69.66(a)    		   415539  NM_001007828.1  NP_001007829.1 
    lizard
    (Anolis carolinensis)    		 Reptilia PTPLAD16
    		 --
    		 70(a)
    		 1 ↔ 1
    		 GL343503.1(246067-269818)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.6972 Transcribed sequence with weak similarity to protein more 79.55(n)    CF239814.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc636322 hypothetical protein MGC63632 75.7(n)   393441  BC055174.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG92671 CG9267 46.87(n)
    36.36(a)    		   34762  NM_135811.2  NP_609655.2 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons PEP6
    AT5G597706
    		 Protein-tyrosine phosphatase-like, PTPLA
    		 22(a)
    20(a)
    		 possible ortholog
    1 ↔ many
    		 5(3297804-3300151)
    5(24079392-24081216)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 6)    		 expressed protein
    (see all 6)    		 25(a)
    22(a)
    (see all 6)    		 1 ↔ many
    possible ortholog
    (see all 6)    		 5(22570585-22573567)
    1(2721518-2723797)


    ENSEMBL Gene Tree for PTPLAD1 (if available)
    TreeFam Gene Tree for PTPLAD1 (if available) 

    Paralogs
    for PTPLAD1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PTPLAD1 gene
    PTPLA2  PTPLAD22  PTPLB2  
    7 SIMAP similar genes for PTPLAD1 using alignment to 6 protein entries:     HACD3_HUMAN (see all proteins):
    PFKFB3    TUBA1C    ATF1    RQCD1    IRF2    PTPLAD2
    PTPLB

    PTPLAD1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PTPLAD1
    PGOHUM00000262252


    Genomic Variants
    for PTPLAD1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/845 NCBI SNPs in PTPLAD1 are shown (see all 845)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 15 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs71644891,2
    		C,F,H--65820830(+) TTACTA/CATCTC 1 -- int1 tfbs311Minor allele frequency- C:0.10NS EA NA WA 1308
    rs1154318551,2
    		--65821333(+) TCCACG/AGCCTA 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1896159011,2
    		--65821454(+) AAACTC/GTTTGT 1 -- int10--------
    rs1921544761,2
    		--65821457(+) CTCTTC/TGTGAG 1 -- int10--------
    rs1436226431,2
    		--65821515(+) CTCTTA/GAGCTA 1 -- int10--------
    rs778050131,2
    		C--65821824(+) TAGAAG/TAGCCA 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1849973291,2
    		--65821879(+) TGGCCA/GGGCGC 1 -- int10--------
    rs1407490921,2
    		--65821925(+) GCCAAA/GGCGGG 1 -- int10--------
    rs1902845741,2
    		--65822137(+) AAGAGA/CGAAAC 1 -- int10--------
    rs1811600651,2
    		--65822172(+) AACAAA/CAAAAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for PTPLAD1 (65822756 - 65870693 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PTPLAD1: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for PTPLAD1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PTPLAD1 for disorders           About GeneDecksing

    2 diseases for PTPLAD1:    About MalaCards
    hepatitis c    hepatitis


    Export disorders for PTPLAD1 gene to outside databases

    Publications
    for PTPLAD1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PTPLAD1 gene, integrated from 9 sources (see all 36):
    (articles sorted by number of sources associating them with PTPLAD1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts. (PubMed id 10747961)1, 2, 3, 9 Courilleau D.... Mester J. (2000)
    2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    3. Human B-ind1 gene promoter: cloning and regulation by histone deacetylase inhibitors. (PubMed id 16516406)1, 2 Sabbah M.... Redeuilh G. (2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Genetic Loci implicated in erythroid differentiation a nd cell cycle regulation are associated with red blood cell traits. (PubMed id 22560525)1 Ding K....Kullo I.J. (2012)
    7. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Identification of proteins associated with ligand-acti vated estrogen receptor a in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. (PubMed id 21182205)1 Tarallo R....Weisz A. (2011)

    External Searches for PTPLAD1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
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    NCBI Bookshelf
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    Genome Databases showing PTPLAD1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51495 HGNC: 24175 AceView: HSPC121 Ensembl:ENSG00000074696 euGenes: HUgn51495
    ECgene: PTPLAD1 H-InvDB: PTPLAD1

    Other Databases showing PTPLAD1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing PTPLAD1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PTPLAD1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for PTPLAD1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for PTPLAD1 gene:
    Search GeneIP for patents involving PTPLAD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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