Aliases for PTP4A1 Gene
External Ids for PTP4A1 Gene
Previous GeneCards Identifiers for PTP4A1 Gene
This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013]
GeneCards Summary for PTP4A1 Gene
PTP4A1 (Protein Tyrosine Phosphatase Type IVA, Member 1) is a Protein Coding gene. Among its related pathways are PAK Pathway and Signaling events mediated by PRL. GO annotations related to this gene include phosphatase activity and protein tyrosine/serine/threonine phosphatase activity. An important paralog of this gene is PTP4A2.
UniProtKB/Swiss-Prot for PTP4A1 Gene
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.