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PTMS Gene

protein-coding   GIFtS: 55
GCID: GC12P006875

Parathymosin

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
parathymosin1 2
ParaT2

External Ids:    HGNC: 96291   Entrez Gene: 57632   Ensembl: ENSG000001593357   OMIM: 1684405   UniProtKB: P209623   
ORGUL members:         

Export aliases for PTMS gene to outside databases

Previous GC identifers: GC12M006676 GC12M006801 GC12P006753 GC12P006745 GC12P006746


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PTMS Gene:
PTMS (parathymosin) is a protein-coding gene.

UniProtKB/Swiss-Prot: PTMS_HUMAN, P20962
Function: Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers
resistance to certain opportunistic infections

Gene Wiki entry for PTMS Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_009759.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the PTMS gene promoter:
         TBP   p53   AP-2alpha isoform 3   AP-2alpha isoform 2   AREB6   FOXO4   deltaCREB   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): PTMS promoter sequence
   Search Chromatin IP Primers for PTMS

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PTMS


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13

PTMS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PTMS gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P006875:  view genomic region     (about GC identifiers)

Start:
6,874,682 bp from pter      End:
6,880,118 bp from pter
Size:
5,437 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PTMS_HUMAN, P20962 (See protein sequence)
Recommended Name: Parathymosin  
Size: 102 amino acids; 11530 Da

Explore the universe of human proteins at neXtProt for PTMS: NX_P20962

Explore proteomics data for PTMS at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys15
  • Modification sites at PhosphoSitePlus

  • See PTMS Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002815.3  
    ENSEMBL proteins: 
     ENSP00000374113   ENSP00000442325   ENSP00000310088  

    PTMS Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for PTMS
    OriGene Custom MassSpec
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    Novus Biologicals PTMS Proteins
    Novus Biologicals PTMS Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PTMS

     
    Search eBioscience for Proteins for PTMS 

     
    antibodies-online proteins for PTMS (8 products) 

     
    antibodies-online peptides for PTMS

    PTMS Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    ThermoFisher Antibody for PTMS
    LSBio Antibodies in human, mouse, rat for PTMS
    antibodies-online antibodies for PTMS (30 products) 

    PTMS Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for PTMS
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PTMS
    Cloud-Clone Corp. CLIAs for PTMS
    Search eBioscience for ELISAs for PTMS 
    antibodies-online kits for PTMS (10 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004931 Pro/parathymosin

    Graphical View of Domain Structure for InterPro Entry P20962

    ProtoNet protein and cluster: P20962

    1 Blocks protein domain: IPB004931 Prothymosin/parathymosin

    UniProtKB/Swiss-Prot: PTMS_HUMAN, P20962
    Similarity: Belongs to the pro/parathymosin family


    Find genes that share domains with PTMS           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PTMS_HUMAN, P20962
    Function: Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers
    resistance to certain opportunistic infections

         Genatlas biochemistry entry for PTMS:
    parathymosin,highly homolog to prothymosin,mainly expressed in liver,kidney,brain,formerly assigned to 17q12-q22

    Phenotypes:
         1 MGI phenotypic allele for Ptms (no phenotypes)

    Find genes that share phenotypes with PTMS           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PTMS
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PTMS

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PTMS
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PTMS

    miRNA
    Products:
        
    miRTarBase miRNAs that target PTMS:
    hsa-mir-193b-3p (MIRT016446), hsa-mir-34a-5p (MIRT025517), hsa-mir-296-3p (MIRT038470), hsa-mir-155-5p (MIRT020881), hsa-mir-423-3p (MIRT042551), hsa-mir-22-3p (MIRT006467), hsa-mir-30a-5p (MIRT028559)

    Block miRNA regulation of human, mouse, rat PTMS using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PTMS (see all 17):
    hsa-miR-3200-5p hsa-miR-185* hsa-miR-300 hsa-miR-486-3p hsa-miR-548x hsa-miR-626 hsa-miR-4283 hsa-miR-548d-3p
    SwitchGear 3'UTR luciferase reporter plasmidPTMS 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PTMS
    Predesigned siRNA for gene silencing in human, mouse, rat PTMS

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PTMS

    Clone
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    OriGene clones in human, mouse for PTMS (see all 6)
    OriGene ORF clones in mouse, rat for PTMS
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PTMS (NM_002824)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PTMS
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PTMS

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for PTMS
    Browse ESI BIO Cell Lines and PureStem Progenitors for PTMS 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PTMS


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytoskeleton2
    cytosol1
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS10854063

    Find genes that share ontologies with PTMS           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PTMS
    Interactions:

        Search GeneGlobe Interaction Network for PTMS

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for PTMS (P209622, 3 ENSP000003100884) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PARP2Q9UGN52, 3, ENSP000002504164MINT-8201899 I2D: score=1 STRING: ENSP00000250416
    ENSG00000206289P287023I2D: score=1 
    ENSG00000227322P287023I2D: score=1 
    ENSG00000228333P287023I2D: score=1 
    ENSG00000231321P287023I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002376immune system process IEA--
    GO:0006260DNA replication TAS10854063

    Find genes that share ontologies with PTMS           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PTMS

    1 Novoseek inferred chemical compound relationship for PTMS gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 18.8 1 8954154 (1)



    Find genes that share compounds with PTMS           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PTMS gene: 
    NM_002824.4  

    Unigene Cluster for PTMS:

    Parathymosin
    Hs.504613  [show with all ESTs]
    Unigene Representative Sequence: BM423440
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000540667 ENST00000389462 ENST00000540874 ENST00000309083(uc001qqq.3)
    ENST00000540828 ENST00000538057(uc001qqr.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PTMS using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PTMS (see all 17):
    hsa-miR-3200-5p hsa-miR-185* hsa-miR-300 hsa-miR-486-3p hsa-miR-548x hsa-miR-626 hsa-miR-4283 hsa-miR-548d-3p
    SwitchGear 3'UTR luciferase reporter plasmidPTMS 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PTMS
    Predesigned siRNA for gene silencing in human, mouse, rat PTMS
    Clone
    Products:
         
    OriGene clones in human, mouse for PTMS (see all 6)
    OriGene ORF clones in mouse, rat for PTMS
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PTMS (NM_002824)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PTMS
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PTMS
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PTMS
    OriGene qSTAR qPCR primer pairs in human, mouse for PTMS
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PTMS
      QuantiTect SYBR Green Assays in human, mouse, rat PTMS
      QuantiFast Probe-based Assays in human, mouse, rat PTMS

    Additional mRNA sequence: 

    BC007616.1 BC017025.1 BC128229.1 

    21 DOTS entries:

    DT.97863320  DT.92459184  DT.100788228  DT.91820157  DT.95226559  DT.92459171  DT.100033013  DT.121122888 
    DT.102829742  DT.95108030  DT.95108035  DT.121122823  DT.121122929  DT.100032121  DT.100044810  DT.121122851 
    DT.121122855  DT.121456184  DT.87000569  DT.95096549  DT.95288021 

    5 AceView cDNA sequences:

    BC017025 NM_002824 BC007616 M24398 Z36803 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PTMS expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCTGCCCCA
    PTMS Expression
    About this image


    PTMS expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 16) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Cushion Mesenchymal Cells Endocardium
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)
     
     Uterus (Reproductive System)
     
     Thyroid (Endocrine System)
    PTMS Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PTMS Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.504613
        Custom PCR Arrays for PTMS
    Primer
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    OriGene qPCR primer pairs and template standards for PTMS
    OriGene qSTAR qPCR primer pairs in human, mouse for PTMS
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    QuantiTect SYBR Green Assays in human, mouse, rat PTMS
    QuantiFast Probe-based Assays in human, mouse, rat PTMS
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PTMS

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for PTMS gene from Selected species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ptms5 parathymosin   --   6 (59.17 cM) 124913681 


    ENSEMBL Gene Tree for PTMS (if available)
    TreeFam Gene Tree for PTMS (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PTMS (see all 97)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1899934631,2
    --6873761(+) GAGGTG/TGAGTG 1 -- us2k10--------
    rs22867291,2
    C,F--6873818(-) CGCTCC/TCTCCC 1 -- us2k1 tfbs3 trp33Minor allele frequency- T:0.11EA NA 1736
    rs1415602561,2
    C--6873850(+) GGTTG-/GGCGGGGG 1 -- us2k10--------
    rs38350301,2
    C--6873852(-) CCCCCC/GCCCAA 1 -- us2k10--------
    rs1130338341,2
    C--6873852(+) TGGGCG/-GGGGG 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs3741692711,2
    C--6873854(+) TTGGG-/C/CGG 
            
    GGGGG
    2 -- us2k1 cds11NA 2
    rs1481962601,2
    --6874394(+) AGGAGC/TTGAGG 1 -- us2k10--------
    rs22867281,2
    C,F,A,H--6874678(-) CCACTC/GCTCAC 1 -- us2k1 tfbs39Minor allele frequency- G:0.24EA NS WA NA 2268
    rs1135160421,2
    F--6874703(+) AAGAAC/TGGGAG 1 -- us2k13Minor allele frequency- T:0.40CSA 5
    rs1157601241,2
    F--6874724(+) TATAAT/CTGGTT 1 -- us2k11Minor allele frequency- C:0.01WA 118

    HapMap Linkage Disequilibrium report for PTMS (6874682 - 6880118 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for PTMS:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv27720CNV Loss19812545
    nsv898635CNV Loss21882294
    nsv832323CNV Loss17160897
    dgv1352n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PTMS
    DNA2.0 Custom Variant and Variant Library Synthesis for PTMS

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 168440    OMIM disorders: --


    Find genes that share disorders with PTMS           About GenesLikeMe

    Genetic Association Database (GAD): PTMS
    Human Genome Epidemiology (HuGE) Navigator: PTMS (3 documents)

    Export disorders for PTMS gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PTMS gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with PTMS)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Parathymosin affects the binding of linker histone H1 to nucleosomes and remodels chromatin structure. (PubMed id 15716277)1, 3, 9 Martic G....Papamarcaki T. (J. Biol. Chem. 2005)
    2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    3. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. (PubMed id 19204726)1, 4 Chapuis J....Lambert J.C. (Mol. Psychiatry 2009)
    4. The sequence of human parathymosin deduced from a cloned human kidney cDNA. (PubMed id 2537638)1, 2 Clinton M.... Horecker B.L. (Biochem. Biophys. Res. Commun. 1989)
    5. Selective interaction between parathymosin and histone H1. (PubMed id 8954154)1, 9 Kondili K....Papamarcaki T. (Eur. J. Biochem. 1996)
    6. Nuclear distribution of prothymosin alpha and parathymosin: evidence that prothymosin alpha is associated with RNA synthesis processing and parathymosin with early DNA replication. (PubMed id 10854063)1, 9 Vareli K....van Driel R. (Exp. Cell Res. 2000)
    7. Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ. (PubMed id 1862085)1, 9 Clinton M....Horecker B.L. (Proc. Natl. Acad. Sci. U.S.A. 1991)
    8. The thymosins. Prothymosin alpha, parathymosin, and beta-thymosins: structure and function. (PubMed id 12852257)1, 9 Hannappel E. and Huff T. (Vitam. Horm. 2003)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5763 HGNC: 9629 AceView: PTMS Ensembl:ENSG00000159335 euGenes: HUgn5763
    ECgene: PTMS H-InvDB: PTMS

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PTMS Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PTMS gene:
    Search GeneIP for patents involving PTMS

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for PTMS  
     OriGene qPCR primer pairs and template standards for PTMS   OriGene Protein Over-expression Lysate for PTMS  
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     OriGene Custom Antibody Services for PTMS   OriGene Custom Protein Services for PTMS  

     
     
     Block miRNA regulation of human, mouse, rat PTMS using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PTMS
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PTMS Predesigned siRNA for gene silencing in human, mouse, rat PTMS
     QuantiFast Probe-based Assays in human, mouse, rat PTMS QuantiTect SYBR Green Assays in human, mouse, rat PTMS
     Custom PCR Arrays for PTMS Search Chromatin IP Primers for PTMS
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PTMS  Search GeneGlobe Interaction Network for PTMS
     Regulatory tfbs in PTMS promoter
     GenScript Custom Purified and Recombinant Proteins Services for PTMS GenScript cDNA clones with any tag delivered in your preferred vector for PTMS
     GenScript Custom Assay Services for PTMS GenScript Custom overexpressing Cell Line Services for PTMS
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     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for PTMS
     Browse Sino Biological Proteins
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     See all of Abcam's Antibodies, Kits and Proteins for PTMS
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     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for PTMS
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     ELISAs for PTMS
     CLIAs for PTMS



     Browse ESI BIO Cell Lines and PureStem Progenitors for PTMS
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PTMS
     SwitchGear 3'UTR luciferase reporter plasmids for PTMS
     SwitchGear Promoter luciferase reporter plasmids for PTMS
     ThermoFisher Antibody for PTMS
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PTMS
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PTMS
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PTMS
     LSBio Antibodies in human, mouse, rat for PTMS
     Browse compounds at ApexBio
     Search Addgene for plasmids for PTMS
      Search eBioscience for proteins for PTMS
      Search eBioscience for elisas for PTMS
      eBioscience FlowRNA Probe Sets
    Customized transgenic rodents for:
     Humanization
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     Translational medicine
     Tissue-specific gene expresssion
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     antibodies-online antibodies for PTMS (30 products)
     antibodies-online kits for PTMS (10 products)
     antibodies-online peptides for PTMS
     antibodies-online proteins for PTMS (8 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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