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PTH Gene

protein-coding GIFtS: 65

GC11M013470

parathyroid hormone
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
PTH1 ^¹, ²
Parathormone ^³
Parathyrin ^³
parathormone ^²
parathyrin ^²

Descriptions
parathyroid hormone ^²
parathyroid hormone 1 ^²

External Ids
HGNC: 9606¹
Entrez Gene: 5741²
UniProtKB: P01270³
Ensembl: ENSG00000152266⁷

Search outside databases for aliases for PTH gene

Previous GC identifers: GC11M014784 GC11M014262 GC11M013552 GC11M013477

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for PTH:

The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates

blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in

this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq]

UniProtKB/Swiss-Prot: PTHY_HUMAN, P01270

Function: PTH elevates calcium level by dissolving the salts in bone and preventing their renal

excretion

Gene Wiki entry for PTH (Parathyroid_hormone)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the PTH gene

Entrez Gene cytogenetic band: 11p15.3-p15.1 Ensembl cytogenetic band: 11p15.2 HGNC cytogenetic band: 11p15.3-p15.1

PTH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M013470: (about GC identifiers)

Start:	13,470,177 bp from pter
End:	13,474,143 bp from pter
Size:	3,967 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000011.8 NT_009237.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: PTHY_HUMAN, P01270 (See protein sequence)

Recommended Name: Parathyroid hormone precursor

Size: 115 amino acids; 12861 Da

Subcellular location: Secreted

PDB structures from and Proteopedia :

1BWX (3D)

1ET1 (3D)

1ET2 (3D)

1FVY (3D)

1HPH (3D)

1HPY (3D)

1HTH (3D)

1ZWA (3D)

1ZWB (3D)

1ZWD (3D)

1ZWE (3D)

1ZWF (3D)

1ZWG (3D)

3C4M (3D)

Secondary accessions: Q4VB48

REFSEQ proteins: NP_000306.1

ENSEMBL proteins:

ENSP00000282091

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Parathyroid Hormone)
	Human Recombinant Proteins from Abnova (PTH)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	NAS	14718574
GO:0005615	extracellular space	IEA	--

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Antibodies for PTH:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for PTH
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Parathyroid Hormone), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (PTH)
	Novus Biologicals Antibodies for PTH

Assays for PTH:

	Invitrogen Assays for PTH
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P01270

ProtoNet protein and cluster: P01270

1 Blocks protein family: IPB001415 Parathyroid hormone

UniProtKB/Swiss-Prot: PTHY_HUMAN, P01270

Similarity: Belongs to the parathyroid hormone family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (PTH)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (PTH)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000315

Applied Biosystems Silencer® siRNAs for PTH

Sigma-Aldrich siRNA and siRNA Panels for PTH

Sigma-Aldrich shRNA Panels and shRNA for PTH

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for PTH
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000315
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000315
untagged cDNA clone in CMV expression vector: NM_000315

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000315

UniProtKB/Swiss-Prot: PTHY_HUMAN, P01270

Function: PTH elevates calcium level by dissolving the salts in bone and preventing their renal

excretion

Genatlas biochemistry entry for PTH:

parathyroid hormone,9.5kDa,formed from a 12.5kDa precursor

9 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Pth):

	craniofacial	endocrine/exocrine gland	growth/size	hematopoietic system
immune system	lethality-prenatal/perinatal	limbs/digits/tail	skeleton

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005179	hormone activity	TAS	10499494
GO:0031856	parathyroid hormone receptor binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for PTH (Your Favorite Gene powered by Ingenuity)

VDR/RXR Activation

GeneDecks PTH for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for PTH

5/123 Interacting proteins for PTH (ENSP00000282091³ P01270²) via UniProtKB, MINT, and/or STRING (see all 123 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
BAT3	P46379²	MINT-63346
FEZ1	Q99689²	MINT-63345
PTH1R	ENSP00000324788³	STRING (score=.997)
CASR	ENSP00000353556³	STRING (score=.993)
CYP27B1	ENSP00000228606³	STRING (score=.993)

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5/13 Gene Ontology (GO) biological process terms (links to tree view) (see all 13 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001501	skeletal system development	TAS	10913913
GO:0006874	cellular calcium ion homeostasis	NAS	--
GO:0007186	G-protein coupled receptor protein signaling pathway	TAS	7797535
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	IEA	--
GO:0007266	Rho protein signal transduction	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for PTH
10/26 Novoseek chemical compound relationships for PTH gene (see all 26 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
calcium	70.49	308	9768650 (7), 7705374 (5), 1291861 (5), 10218771 (4) (see all 99)
deoxypyridinoline	67.32	15	18004084 (2), 14555415 (1), 19158198 (1), 18999899 (1) (see all 11)
1,25 dihydroxy vitamin d3	66.74	10	9626120 (2), 10077002 (1), 12788900 (1), 17293108 (1) (see all 9)
doxercalciferol	56.99	3	16282676 (3)
phosphorus	54.67	43	8647946 (8), 15486872 (3), 16160737 (2), 18587716 (2) (see all 16)
procollagen	52.08	12	16352693 (2), 12788900 (1), 12381951 (1), 15049968 (1) (see all 7)
forskolin	49.71	16	12209875 (4), 2175562 (1), 18450967 (1), 9572838 (1) (see all 8)
cyclic amp	38.42	16	12522076 (3), 2175562 (1), 8861839 (1), 9832466 (1) (see all 9)
ribonucleic acid	36.19	3	10323401 (1), 9661591 (1), 15554353 (1)
hydroxyproline	35.60	6	8450043 (2), 15526839 (1), 10536933 (1), 14699686 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (PTH)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (PTH)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000315

Sigma-Aldrich siRNA and siRNA Panels for PTH

Sigma-Aldrich shRNA Panels and shRNA for PTH

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000315

REFSEQ mRNAs for PTH gene:

NM_000315.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000315

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000315
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000315
                                 untagged cDNA clone in CMV expression vector: NM_000315

Additional cDNA sequence:

BC096142.1 BC096143.1 BC096144.3 BC096145.1 V00597.1

1 DOTS entry:

DT.318355

24/100 AceView cDNA sequences (see all 100 ):

AI457923 W37708 W37306 AI050896 AI092021 NM_000315 N90261 N89821

AA888818 W56886 BX106232 W39202 AA037414 AI028087 AI077978 V00597

W38966 BX103059 AA845431 W56235 AA846633 AA372113 AI167763 AI051997

highest scoring ESTs for PTH:

AA330490 AA372113 AI028087 BX103059 BX106232 T29548 V00597 W19765 W20239 W32642

Unigene Cluster for PTH:

Parathyroid hormone

Hs.37045 [show with all ESTs]

Unigene Representative Sequence: NM_000315

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000282091

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

PTH expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for PTH

¹ / ² / ³

4 probe-sets matching PTH gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
708_at²^{, 3}	U95-A	1	1.00	1.00	0.89	1.06	J00301	0.20	1.00	0.72	1
34399_at²^{, 3}	U95-A	1	1.00	1.00	0.81	1.07	AI028087	0.80	1.00	0.91	1
206977_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_000315	0.60	1.00	0.82	1
206977_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTGCTAATTC

SOURCE GeneReport for Unigene cluster: Hs.37045
Expression variation in blood from EXPOLDB for PTH

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for PTH gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	PTH¹	--	parathyroid hormone	90.43(n) 86.09(a)	403986 NM_001003302.1 NP_001003302.1
chimpanzee (Pan troglodytes)	PTH¹	--	parathyroid hormone	100(n) 100(a)	466447 XM_001171819.1 XP_001171819.1
cow (Bos taurus)	PTH¹	--	parathyroid hormone	88.7(n) 85.22(a)	280903 NM_173954.2 NP_776379.2
rat (Rattus norvegicus)	Pth¹	--	parathyroid hormone	78.26(n) 71.3(a)	24694 NM_017044.1 NP_058740.1
mouse (Mus musculus)	Pth^{1, 5}	7 (52.50 cM)⁵	parathyroid hormone^{1, 5}	78.55(n)¹ 67.83(a)¹	19226¹ NM_020623.2¹ NP_065648.1¹ AF066075⁵ AK138677⁵ (see all 6)

About this table Species with no ortholog for PTH

ENSEMBL Gene Tree for PTH

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/43 NCBI SNPs in PTH are shown (see all 43 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 33)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs307247^1,2	A,C,F,H,O	13470054(-)	`ATCAAC/TGTTTT`	1	--	ng5¹		11		EA NA EU WA	696
	rs2593570^1,2	A,C,F,H,O	13475168(-)	`CCAGGC/AAAATA`	1	--	ng3¹		7		NA EU EA WA	552
	rs1380144^1,2	C,F,H	13474470(-)	`TTTGGA/GTTTTA`	1	--	ng3¹		4		EU EA WA	390
	rs16912873^1,2	F,H	13470209(+)	`ACTTAT/CGATCA`	1	--	ut3¹ ese³		7		NA EU EA WA	560
--	rs307248^1,2	A,C	13469941(-)	`TAAAGG/TGGTCC`	1	--	ng5¹		0	--	--	--	--
	rs1900560^1,2	H	13476035(-)	`cagtcT/Ggagtg`	1	--	ng3¹		4		EU EA WA	420
	rs6256^1,2	A,C,F,H	13470629(-)	`GGCCCC/AGAAAA`	1	R/R	syn¹ ese³		14		MN CSAM EA NA EU WA	1238
--	rs694^1,2	A,C,F,H,O	13470993(-)	`TGCTTG/ATCCTT`	1	--	int¹		14		MN CSAM EA NA EU WA	1232
	rs177706^1,2	A,C,F,H,O	13471081(-)	`TTCTCA/GTGAAA`	1	--	int¹		17		NS MN CSAM EA NA EU WA	1068
	rs192802^1,2	A,C,F,H,O	13472770(-)	`TGAGAC/TGAGGT`	1	--	int¹		17		EA NA NS EU WA	2310

About this table

HapMap Linkage Disequilibrium images for PTH (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 168450 disorders: 146200 146200

UniProtKB/Swiss-Prot: PTHY_HUMAN, P01270

Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]. FIH

exist both as autosomal dominant and recessive forms of hypoparathyroidism

10/52 Novoseek disease relationships for PTH gene (see all 52 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
hyperparathyroidism secondary	81.62	20	17854393 (2), 12940896 (2), 12753275 (2), 9717845 (2) (see all 12)
hypercalcemia	81.34	58	1849762 (4), 16077176 (4), 1993319 (3), 10660809 (3) (see all 35)
hyperparathyroidism primary	80.78	31	16491288 (3), 1689222 (2), 8369362 (2), 10468923 (2) (see all 20)
parathyroid adenoma	78.85	17	2199477 (2), 10704427 (2), 8626826 (1), 15775480 (1) (see all 11)
hyperparathyroidism	73.34	16	16263810 (1), 9730564 (1), 1643722 (1), 7903311 (1) (see all 13)
pseudohypoparathyroidism, type ib	70.63	1	10971097 (1)
hyperphosphatemia	69.17	5	17178702 (2), 10620210 (1), 12940896 (1), 12753275 (1)
hypoparathyroidism	68.52	14	9768650 (3), 1993319 (2), 7752497 (1), 17721071 (1) (see all 7)
renal osteodystrophy	68.45	3	10077343 (2), 8258962 (1)
bone diseases	62.42	8	8671970 (4), 10620210 (1), 18587716 (1), 11277262 (1) (see all 5)

About this table

Genatlas disease: PTH

hypoparathyroidism,familial,isolated,dominant and recessive types

Human Gene Mutation Database: PTH
Genetic Association Database: PTH
Human Genome Epidemiology Navigator: PTH (79 documents)
Tumor Gene Database: PTH
Breast Cancer Gene Database: PTH

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/435 PubMed articles for PTH gene (see all 435 ):

[Polymorphism of parathyroid hormone gene and its association with bone mineral density of Han nationality women in Beijing area] (PubMed id 12905817)^{1, 3, 6} Li M....Xing X.P. (2001)
Regional mapping of the parathyroid hormone gene (PTH) by cytogenetic and molecular studies. (PubMed id 1672845)^{1, 2, 3} Tonoki H....Niikawa N. (1991)
Distinct association of gene polymorphisms of estrogen receptor and vitamin D receptor with lumbar spondylosis in post-menopausal women. (PubMed id 16362385)^{3, 6} Koshizuka Y....Kawaguchi H. (2006)
[Effects of parathyroid hormone gene polymorphism on cardiovascular mortality] (PubMed id 16272640)^{3, 6} Tsujimoto Y....Nishizawa Y. (2005)
Bone mineral density and five prominent candidate genes in Chinese men: associations, interaction effects and their implications. (PubMed id 15917161)^{3, 6} Lei S.F....Deng H.W. (2005)
Contribution of genotype and ethnicity to bone mineral density variation in Caucasians and Chinese: a test for five candidate genes for bone mass. (PubMed id 16117875)^{3, 6} Dvornyk V....Deng H.W. (2005)
Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)^{3, 4} Zhang Z. and Henzel W.J. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
[Association study of RFLP of parathyroid hormone gene and bone mineral density in postmenopausal women] (PubMed id 15639837)^{3, 6} Li D....Wang Q. (2003)
Parathyroid hormone gene with bone phenotypes in Chinese. (PubMed id 12893275)^{3, 6} Zhou X.G....Deng H.W. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 5741	HGNC: 9606	AceView: PTH	Ensembl:ENSG00000152266	euGenes: HUgn5741
ECgene: PTH	H-InvDB: PTH

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
Wikipedia	http://en.wikipedia.org/wiki/Parathyroid_hormone

Licensable Technologies for PTH
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for PTH:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for PTH-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for PTH		Antibodies for PTH
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for PTH		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (PTH)
	Antibodies (PTH)
	Chimera RNAi (PTH)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (Parathyroid Hormone)

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Search Tocris compounds for PTH

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for PTH

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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PTH Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for PTH

Summaries
for PTH

Genomic Location
for PTH

Proteins
for PTH

Protein Domains/
Families
for PTH

Gene Function
for PTH

Pathways & Interactions
for PTH

Drugs & Compounds
for PTH

Transcripts
for PTH

Expression
for PTH

Orthologs
for PTH

Paralogs
for PTH

SNPs/Variants
for PTH

Disorders & Mutations
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Medical News
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Publications
for PTH

Search for PTH

Genome Databases showing PTH

Other Databases showing PTH

Specialized Databases showing PTH

Licensable Technologies
for PTH

Services
for PTH

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

PTH Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor PTH

Summariesfor PTH

Genomic Locationfor PTH

Proteinsfor PTH

Protein Domains/Familiesfor PTH

Gene Functionfor PTH

Pathways & Interactionsfor PTH

Drugs & Compoundsfor PTH

Transcriptsfor PTH

Expression for PTH

Orthologsfor PTH

Paralogsfor PTH

SNPs/Variantsfor PTH

Disorders & Mutationsfor PTH

Medical Newsfor PTH

Publicationsfor PTH

Search for PTH

Genome Databases showing PTH

Other Databases showing PTH

Specialized Databases showing PTH

Licensable Technologiesfor PTH

Servicesfor PTH

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for PTH

Summaries
for PTH

Genomic Location
for PTH

Proteins
for PTH

Protein Domains/
Families
for PTH

Gene Function
for PTH

Pathways & Interactions
for PTH

Drugs & Compounds
for PTH

Transcripts
for PTH

Expression
for PTH

Orthologs
for PTH

Paralogs
for PTH

SNPs/Variants
for PTH

Disorders & Mutations
for PTH

Medical News
for PTH

Publications
for PTH

Licensable Technologies
for PTH

Services
for PTH