Aliases for PTGES2 Gene
External Ids for PTGES2 Gene
Previous HGNC Symbols for PTGES2 Gene
Previous GeneCards Identifiers for PTGES2 Gene
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
GeneCards Summary for PTGES2 Gene
PTGES2 (Prostaglandin E Synthase 2) is a Protein Coding gene. Diseases associated with PTGES2 include patent ductus arteriosus and colorectal cancer. Among its related pathways are Ca-dependent events and Metabolism. GO annotations related to this gene include electron carrier activity and prostaglandin-E synthase activity.
UniProtKB/Swiss-Prot for PTGES2 Gene
Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2).