Aliases for PTGES2 Gene
External Ids for PTGES2 Gene
Previous HGNC Symbols for PTGES2 Gene
Previous GeneCards Identifiers for PTGES2 Gene
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
GeneCards Summary for PTGES2 Gene
PTGES2 (Prostaglandin E Synthase 2) is a Protein Coding gene. Diseases associated with PTGES2 include Bladder Papillary Transitional Cell Neoplasm and Urinary Tract Papillary Transitional Cell Benign Neoplasm. Among its related pathways are Innate Immune System and Metabolism. Gene Ontology (GO) annotations related to this gene include heme binding and lyase activity.
UniProtKB/Swiss-Prot for PTGES2 Gene
Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2).