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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PSPN Gene

protein-coding   GIFtS: 54
GCID: GC19M006326

persephin

 Explore 10 diseases affiliated with
PSPN via our new
 Human Malady Compendium 
Biological research products
for PSPN
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Persephin1
PSP1 2 3

External Ids:    HGNC: 95791   Entrez Gene: 56232   Ensembl: ENSG000001256507   OMIM: 6029215   UniProtKB: O605423   

Export aliases for PSPN gene to outside databases

Previous GC identifers: GC19M006469 GC19M006315 GC19M006135


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PSPN:
The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are
important for the proper development and maintenance of the nervous system. These factors promote neuronal survival
and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The
encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and
neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents
their degeneration after 6-hydroxydopamine treatment in vivo. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: PSPN_HUMAN, O60542
Function: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011255.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PSPN gene promoter:
         AP-2alpha isoform 3   AML1a   SREBP-1c   NRSF form 1   MyoD   NRSF form 2   SREBP-1b   SREBP-1a   NRF-2   AP-2alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPSPN promoter sequence
   Search SABiosciences Chromatin IP Primers for PSPN

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PSPN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

PSPN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PSPN gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M006326:  view genomic region     (about GC identifiers)

Start:
6,375,305 bp from pter      End:
6,375,860 bp from pter
Size:
556 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PSPN_HUMAN, O60542 (See protein sequence)
Recommended Name: Persephin precursor  
Size: 156 amino acids; 16600 Da
Subunit: Homodimer; disulfide-linked (By similarity)
Subcellular location: Secreted

Explore the universe of human proteins at neXtProt for PSPN: NX_O60542

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O60542

  • PSPN Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004149.1  
    ENSEMBL proteins: 
     ENSP00000245810  
    Reactome Protein details: O60542
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for PSPN (Persephin)
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    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: PSPN
    OriGene Custom Protein Services for PSPN 
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    Novus Biologicals PSPN Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PSPN

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--


    PSPN for ontologies           About GeneDecksing



    PSPN Antibody Products: 
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    Uscn ELISAs and CLIAs for PSPN


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PSPN for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001839 TGF-b_C

    Graphical View of Domain Structure for InterPro Entry O60542

    ProtoNet protein and cluster: O60542

    2 Blocks protein families:
    IPB001839 Transforming growth factor beta (TGFb)
    IPB002400 Growth factor cystine knot superfamily signature


    UniProtKB/Swiss-Prot: PSPN_HUMAN, O60542
    Similarity: Belongs to the TGF-beta family. GDNF subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: PSPN_HUMAN, O60542
    Function: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons

         Genatlas biochemistry entry for PSPN:
    persephin,neurotrophic factor,related to GDNF and neurturin,involved in the survival of several neuronal cell types
    from the central nervous system

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PSPN
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PSPN (see all 7)
    OriGene shRNA RFP: PSPN
    OriGene siRNA: PSPN
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PSPN

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PSPN 

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    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for PSPN

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding TAS9491986
    GO:0008083growth factor activity IEA--


    PSPN for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Pspntm1Bjh for PSPN
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Pspn):
     homeostasis/metabolism  nervous system 

    PSPN for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Development EGFR signaling pathway
    Development GDNF family signaling0.45
    GDNF-Family Ligands and Receptor Interactions0.21
    Development_GDNF family signaling0.45
    2NCAM signaling for neurite out-growth
    NCAM signaling for neurite out-growth1.00
    NCAM1 interactions0.62
    3Axon guidance
    Axon guidance1.00
    Developmental Biology0.69

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for PSPN
        Development GDNF family signaling

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for PSPN
        GDNF-Family Ligands and Receptor Interactions

    1 GeneGo (Thomson Reuters) Pathway for PSPN
        Development GDNF family signaling

    4        Reactome Pathways for PSPN
        Developmental Biology
    NCAM1 interactions
    NCAM signaling for neurite out-growth
    Axon guidance



    PSPN for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PSPN

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for PSPN (O605423 ENSP000002458104) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GFRA4Q9GZZ73, ENSP000003134234I2D: score=2 STRING: ENSP00000313423
    ARTNENSP000003919984STRING: ENSP00000391998
    GDNFENSP000003171454STRING: ENSP00000317145
    GFRA1ENSP000003937254STRING: ENSP00000393725
    NCAM1ENSP000003184724STRING: ENSP00000318472
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001658branching involved in ureteric bud morphogenesis IEA--
    GO:0007399nervous system development TAS9491986
    GO:0007411axon guidance TAS--
    GO:0007417central nervous system development TAS9491986


    PSPN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PSPN for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PSPN
    4 Novoseek chemical compound relationships for PSPN gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 51.8 5 9576965 (1), 9740802 (1), 10484767 (1), 11222636 (1) (see all 5)
    6-hydroxydopamine 44 2 9491986 (1), 11043566 (1)
    dopamine 14.2 2 12953054 (1)
    glutamate 0 2 10356295 (1), 10686085 (1)

    Search CenterWatch for drugs/clinical trials and news about PSPN 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PSPN gene: 
    NM_004158.2  

    Unigene Cluster for PSPN:

    Persephin
    Hs.248159  [show with all ESTs]
    Unigene Representative Sequence: BE799721
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000245810(uc010xja.2)

    miRNA
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    OriGene siRNA: PSPN
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PSPN
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PSPN

    Additional cDNA sequence: 

    AF040962.1 BC143894.1 

    3 DOTS entries:

    DT.92035523  DT.97861638  DT.95213128 

    24/302 AceView cDNA sequences (see all 302):

    H41752 BM975394 BU617787 BG170718 AK055490 BQ004602 BU849836 BX488964 
    CA843785 BM722851 BU175972 BF792427 AA381284 BU609071 BQ894306 AI394578 
    BF081906 BQ350170 BQ071344 BQ961773 BM818653 CA438420 BQ925302 AW007716 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PSPN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCTGGCGCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PSPN Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PSPN

    SOURCE GeneReport for Unigene cluster: Hs.248159
        SABiosciences Expression via Pathway-Focused PCR Arrays including PSPN: 
              Growth Factors in human mouse rat
              Neurotrophins & Receptors in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for PSPN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for PSPN gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia PSPN6
    --
    53(a)
    1 ↔ 1
    2(76458837-76459112)
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch1073-141i10.16
    si:ch1073-141i10.1
    41(a)
    1 → many
    6(3266343-3266657)


    ENSEMBL Gene Tree for PSPN (if available)
    TreeFam Gene Tree for PSPN (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PSPN gene
    GDNF2  ARTN2  NRTN2  
    2 SIMAP similar genes for PSPN using alignment to 2 protein entries:     PSPN_HUMAN (see all proteins):
    NRTN    ARTN

    PSPN for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/87 NCBI SNPs in PSPN are shown (see all 87    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs104211751,2
    C,F,A,H,--6374813(+) GTTTCT/CTCCTG 2 -- ds5001 int123Minor allele frequency- C:0.37NS EA NA WA CSA EU 3666
    rs1142414821,2
    C,F,--6375046(+) AACTGG/AGACAT 2 -- ds5001 ut312Minor allele frequency- A:0.02WA NA 238
    rs1924809951,2
    --6375161(+) AAGGCC/TGGGAG 2 -- ds5001 ut310--------
    rs1146964221,2
    F,--6375162(+) AGGCCG/AGGAGA 2 -- ut31 ds50011Minor allele frequency- A:0.03WA 118
    rs1460995791,2
    C,--6375307(+) CCCTC-/AGCCACC 3 G G* ds5001 fra10--------
    rs756195831,2
    C--6375314(+) CCACCA/CCAGCC 3 W C mis1 ds50010--------
    rs768652111,2
    C--6375355(-) ACCGCG/TGGCAG 3 G W mis1 ds50010--------
    rs803363231,2
    F,--6375368(+) CGGTCA/GTCGAG 3 D ds5001 syn11Minor allele frequency- G:0.12NA 120
    rs1380938841,2
    --6375471(+) GGGTGC/TGGGCA 3 H R mis1 ds50010--------
    rs1998815601,2
    C,--6375505(+) GTAGCA/GGAAGA 3 R C ds5001 mis10--------

    HapMap Linkage Disequilibrium report for PSPN (6375305 - 6375860 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PSPN: --
    Human Gene Mutation Database (HGMD): PSPN

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PSPN
    DNA2.0 Custom Variant and Variant Library Synthesis for PSPN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PSPN for disorders           About GeneDecksing

    OMIM gene information: 602921    OMIM disorders: --

    10 diseases for PSPN:    About MalaCards
    neurodegenerative disease    multiple endocrine neoplasia    neuronitis    hirschsprung's disease
    parkinson's disease    thyroid carcinoma    pancreatic cancer    thyroiditis
    pancreatitis    carcinoma

    1 disease from the University of Copenhagen DISEASES database for PSPN:
    Hirschsprung's disease

    4 Novoseek disease relationships for PSPN gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hirschsprung disease 63.8 1 18970938 (1)
    neurodegenerative diseases 34.8 1 10652334 (1)
    parkinson disease 11.2 2 20350599 (2)
    tumors 5.27 1 12679485 (1)

    Human Genome Epidemiology (HuGE) Navigator: PSPN (1 document)

    Export disorders for PSPN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PSPN gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with PSPN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Persephin, a novel neurotrophic factor related to GDNF and neurturin. (PubMed id 9491986)1, 2, 9 Milbrandt J.... Johnson E.M. (1998)
    2. Assignment of persephin (PSPN), a human neurotrophic factor, to chromosome 19p13.3 by radiation hybrid mapping and somatic cell hybrid PCR. (PubMed id 10072588)1, 3, 9 Chadwick B.P....Slaugenhaupt S.A. (1998)
    3. GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin. (PubMed id 9740802)1, 9 Enokido Y....Davies A.M. (1998)
    4. Human glial cell line-derived neurotrophic factor receptor alpha4 is the receptor for persephin and is predomonantly expressed in normal and malignant thyroid medullary cells. (PubMed id 11116144)1, 9 Lindahl M.... Saarma M. (2001)
    5. Neurturin, persephin, and artemin in the human pre- and full-term newborn and adult hippocampus and fascia dentata. (PubMed id 15829225)1, 9 Quartu M....Del Fiacco M. (2005)
    6. Persephin signaling through GFRalpha1: the potential for the treatment of Parkinson's disease. (PubMed id 20350599)1, 9 Sidorova Y.A....Bespalov M.M. (2010)
    7. Polymorphisms in the genes encoding the 4 RET ligands, GDNF, NTN, ARTN, PSPN, and susceptibility to Hirschsprung disease. (PubMed id 18970938)1, 9 Fernandez R.M....Borrego S. (2008)
    8. GDNF, RET and GFRalpha-1-3 mRNA expression in the developing human spinal cord and ganglia. (PubMed id 10380959)1, 9 Widenfalk J....Spenger C. (1999)
    9. PSPN/GFRalpha4 has a significantly weaker capacity than GDNF/GFRalpha1 to recruit RET to rafts, but promotes neuronal survival and neurite outgrowth. (PubMed id 15225646)1, 9 Yang J....Saarma M. (2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5623 HGNC: 9579 AceView: GTF2F1andPSPN Ensembl:ENSG00000125650 euGenes: HUgn5623
    ECgene: PSPN H-InvDB: PSPN

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PSPN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PSPN gene:
    Search GeneIP for patents involving PSPN

    GeneCards and IP:
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