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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PSPC1 Gene

protein-coding   GIFtS: 51
GCID: GC13M020249

Paraspeckle Component 1

  Search for PSPC1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Paraspeckle Component 11 2
PSP12 3 5
Paraspeckle Protein 12 3

External Ids:    HGNC: 203201   Entrez Gene: 552692   Ensembl: ENSG000001213907   OMIM: 6124085   UniProtKB: Q8WXF13   
ORGUL members:         
NONCODE14:n405986 n411720      

Export aliases for PSPC1 gene to outside databases

Previous GC identifers: GC13M019178 GC13M018046 GC13M018047 GC13M019146 GC13M001053


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PSPC1 Gene:
This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to
splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include
a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which
include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the
control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in
paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar
periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this
gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has
been identified. (provided by RefSeq, Aug 2011)

GeneCards Summary for PSPC1 Gene: 
PSPC1 (paraspeckle component 1) is a protein-coding gene, and is affiliated with the lncRNA class. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is NONO.

UniProtKB/Swiss-Prot: PSPC1_HUMAN, Q8WXF1
Function: Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in
Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers (By similarity).
Together with NONO, required for the formation of nuclear paraspeckles




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.2  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PSPC1 gene promoter:
         E2F-3a   E2F-4   E2F-5   Pax-5   E2F-2   LCR-F1   Nkx5-1   CREB   Zic1   deltaCREB   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for PSPC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PSPC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.11   Ensembl cytogenetic band:  13q12.11   HGNC cytogenetic band: 13q11

PSPC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PSPC1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M020249:  view genomic region     (about GC identifiers)

Start:
20,248,896 bp from pter      End:
20,357,142 bp from pter
Size:
108,247 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for PSPC1

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PSPC1_HUMAN, Q8WXF1 (See protein sequence)
Recommended Name: Paraspeckle component 1  
Size: 523 amino acids; 58744 Da
Subunit: Forms heterodimers with NONO; this involves formation of a coiled coil domain by helices from both
proteins. Found in a RNP complex with CAT2 transcribed nuclear RNA (CTN-RNA). Interaction with NONO is required
for its targeting to paraspeckles and perinucleolar caps. Interacts with SFPQ (By similarity)
Subcellular location: Nucleus, nucleolus. Nucleus matrix (By similarity). Cytoplasm (By similarity). Nucleus
speckle. Note=In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles.
Colocalizes with NONO and SFPQ in paraspeckles and perinucleolar caps in a RNA-dependent manner. May cycles
between paraspeckles and nucleolus. In telophase, when daughter nuclei form, localizes to perinucleolar caps
Sequence caution: Sequence=BAA91924.1; Type=Erroneous termination; Positions=14; Note=Translated as Lys;
1 PDB 3D structure from and Proteopedia for PSPC1:
3SDE (3D)    
Secondary accessions: Q5JTQ3 Q8NCZ9 Q8WXE8 Q9NV36
Alternative splicing: 2 isoforms:  Q8WXF1-1   Q8WXF1-2   

Explore the universe of human proteins at neXtProt for PSPC1: NX_Q8WXF1

Explore proteomics data for PSPC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WXF1

  • PSPC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PSPC1 Protein Expression
    REFSEQ proteins: NP_001035879.1  
    ENSEMBL proteins: 
     ENSP00000436038   ENSP00000435921   ENSP00000343966   ENSP00000393069  

    Human Recombinant Protein Products for PSPC1: 
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    Cloud-Clone Corp. Proteins for PSPC1 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm ----
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IEA--
    GO:0016363nuclear matrix IEA--

    PSPC1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RBM: RNA binding motif (RRM) containing

    3 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR012975 NOPS
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q8WXF1

    ProtoNet protein and cluster: Q8WXF1

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB012975 NOPS


    UniProtKB/Swiss-Prot: PSPC1_HUMAN, Q8WXF1
    Similarity: Belongs to the PSPC family
    Similarity: Contains 2 RRM (RNA recognition motif) domains


    PSPC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PSPC1_HUMAN, Q8WXF1
    Function: Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in
    Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers (By similarity).
    Together with NONO, required for the formation of nuclear paraspeckles

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI16148043
         
    PSPC1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PSPC1:
     Decreased Wnt reporter activit 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Pspc1):
     behavior/neurological 

    PSPC1 for phenotypes           About GeneDecksing

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PSPC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/27 Interacting proteins for PSPC1 (Q8WXF11, 2, 3 ENSP000003439664) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NONOQ152331, 3, ENSP000002760794EBI-1392258,EBI-350527 I2D: score=4 STRING: ENSP00000276079
    LRIF1Q5T3J32, 3MINT-65061 I2D: score=4 
    WBP4O755542, 3, ENSP000003688014MINT-73043 I2D: score=3 STRING: ENSP00000368801
    SFPQP232463, ENSP000003497484I2D: score=3 STRING: ENSP00000349748
    AGO3Q9H9G73, ENSP000003622874I2D: score=2 STRING: ENSP00000362287
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--

    PSPC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PSPC1

    Search CenterWatch for drugs/clinical trials and news about PSPC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PSPC1 gene: 
    NM_001042414.2  

    Unigene Cluster for PSPC1:

    Paraspeckle component 1
    Hs.213198  [show with all ESTs]
    Unigene Representative Sequence: NR_044998
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000497722 ENST00000471658 ENST00000492741 ENST00000338910(uc021rgx.1)
    ENST00000427943
    miRNA
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    Additional mRNA sequence: 

    AF448795.1 AF449627.1 AK090873.1 AK301554.1 CR457272.1 NR_003272.2 NR_044998.1 

    17 DOTS entries:

    DT.120781485  DT.100824580  DT.100824577  DT.115917  DT.97818050  DT.95162834  DT.97846641  DT.100027436 
    DT.120781442  DT.120785177  DT.92443035  DT.97775653  DT.120781513  DT.92416065  DT.91985431  DT.95157701 
    DT.99993135 

    24/246 AceView cDNA sequences (see all 246):

    BQ687052 BM312104 BF435523 CD367168 AA815372 BM678008 CB106334 CD675694 
    AA600208 AA761602 CF127194 AI912629 CB214993 CD679068 BQ023992 BP368623 
    BX105138 AI572804 CB528989 N48797 AW268829 CA428856 AW820130 BM985195 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for PSPC1 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12 ^ 13
    SP1:                                                              -           -                                                   
    SP2:                                                              -     -     -     -     -     -     -     -                     
    SP3:                                                              -     -     -     -     -     -     -     -           -         
    SP4:              -                                                                                                               
    SP5:                                                                          -                                                   


    ECgene alternative splicing isoforms for PSPC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PSPC1 expression in normal human tissues (normalized intensities)      PSPC1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATATTAAA
    PSPC1 Expression
    About this image


    PSPC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/36 selected tissues (see all 36) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Breast
             breast ; myoepithelial cells   
             breast lobular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   

    See PSPC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PSPC1

    SOURCE GeneReport for Unigene cluster: Hs.213198

    UniProtKB/Swiss-Prot: PSPC1_HUMAN, Q8WXF1
    Tissue specificity: Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PSPC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PSPC1 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pspc11 , 5 paraspeckle protein 11, 5 92.15(n)1
    97.89(a)1
      14 (28.40 cM)5
    666451  NM_025682.31  NP_079958.31 
     567224415 
    chicken
    (Gallus gallus)
    Aves PSPC11 paraspeckle component 1 82.08(n)
    88.82(a)
      418955  NM_001030831.1  NP_001026002.1 
    lizard
    (Anolis carolinensis)
    Reptilia PSPC16
    Uncharacterized protein
    83(a)
    1 ↔ 1
    3(187064008-187095613)
    zebrafish
    (Danio rerio)
    Actinopterygii pspc11 paraspeckle component 1 68.67(n)
    71.08(a)
      692285  NM_001045258.1  NP_001038723.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta nonA-l6
    nonA6
    no on or off transient A
    23(a)
    20(a)
    many ↔ many
    many ↔ many
    3R(12465927-12468834)
    X(16255566-16265580)
    worm
    (Caenorhabditis elegans)
    Secernentea psf-11 Protein PSF-1 52.89(n)
    45.15(a)
      175844  NM_065894.3  NP_498295.3 


    ENSEMBL Gene Tree for PSPC1 (if available)
    TreeFam Gene Tree for PSPC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PSPC1 gene
    NONO2  SFPQ2  
    2 SIMAP similar genes for PSPC1 using alignment to 1 protein entry:     PSPC1_HUMAN:
    SFPQ    NONO

    PSPC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2452 SNPs in PSPC1 are shown (see all 2452)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1505100831,2
    C--1202141(+) AAATA-/AATAAATA 2 -- ds50010--------
    rs718107531,2
    C--1202142(+) AATAA-/AAT/AT
            
    ATAGG
    2 -- ds50010--------
    rs1848094451,2
    --1202181(+) TAGATA/GTGAGG 2 -- ds50010--------
    rs95796441,2
    C,F,H--1202188(+) GAGGAG/ATTTGG 2 -- ds500112Minor allele frequency- A:0.12NA NS EA WA 922
    rs1464939161,2
    C--1202242(+) TCCTCA/GCAAGT 2 -- ds50010--------
    rs1482871511,2
    C--1202283(+) ATCTT-/ACTC  
            
    AGTAG
    2 -- ds50010--------
    rs352414891,2
    C--1202413(+) CTGACTGTT/-  
            
    TGTTT
    2 -- ds50011Minor allele frequency- -:0.00NA 2
    rs559976981,2
    C--1202508(+) TGAAAA/GGCTGG 2 -- ds50010--------
    rs1897300941,2
    --1202660(+) CATGCA/GGTTAA 2 -- nc-transcript-variant0--------
    rs2018512981,2
    C--1202699(+) TAGAC-/TTTTATC 2 -- nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for PSPC1 (20248896 - 20357142 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for PSPC1 (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2672732CNV Deletion23128226
    dgv334e199CNV Deletion23128226
    esv2747051CNV Deletion23290073
    esv2675516CNV Deletion23128226
    nsv826574CNV Loss20364138
    dgv1551n71CNV Loss21882294
    dgv1552n71CNV Loss21882294
    nsv455826CNV Loss19166990
    nsv899860CNV Loss21882294
    nsv899856CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PSPC1 for disorders           About MalaCards
    OMIM gene information: 612408    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for PSPC1:
    Western equine encephalitis

    PSPC1 for disorders           About GeneDecksing


    Export disorders for PSPC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PSPC1 gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with PSPC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Paraspeckles: a novel nuclear domain. (PubMed id 11790299)1, 2, 3, 9 Fox A.H....Lamond A.I. (2002)
    2. P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner. (PubMed id 16148043)1, 2, 9 Fox A.H.... Lamond A.I. (2005)
    3. Structure of the heterodimer of human NONO and paraspeckle protein component 1 and analysis of its role in subnuclear body formation. (PubMed id 22416126)1, 2 Passon D.M.... Bond C.S. (2012)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. (PubMed id 19217333)1, 9 Clemson C.M....Lawrence J.B. (2009)
    6. Expression and functional significance of mouse paraspeckle protein 1 on spermatogenesis. (PubMed id 15140795)1, 9 Myojin R....Kurihara Y. (2004)
    7. MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles. (PubMed id 19188602)1, 9 Sasaki Y.T....Hirose T. (2009)
    8. p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor. (PubMed id 12810069)1, 9 Ishitani K....Kato S. (2003)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55269 HGNC: 20320 AceView: PSPC1 Ensembl:ENSG00000121390 euGenes: HUgn55269
    ECgene: PSPC1 H-InvDB: PSPC1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PSPC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PSPC1 gene:
    Search GeneIP for patents involving PSPC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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