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Aliases for PSORS1C3 Gene

Subcategory (RNA class) for PSORS1C3 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for PSORS1C3 Gene

  • Psoriasis Susceptibility 1 Candidate 3 (Non-Protein Coding) 2 3 5
  • Psoriasis Susceptibility 1 Candidate 3 2
  • Non-Protein Coding RNA 196 2
  • NCRNA00196 3

External Ids for PSORS1C3 Gene

Previous GeneCards Identifiers for PSORS1C3 Gene

  • GC00U991169
  • GC06U900577
  • GC06M031250
  • GC06M031142
  • GC06M031143
  • GC06M031267
  • GC06M031302
  • GC06M031358

Summaries for PSORS1C3 Gene

GeneCards Summary for PSORS1C3 Gene

PSORS1C3 (Psoriasis Susceptibility 1 Candidate 3 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with PSORS1C3 include Psoriasis Susceptibility 1 and Psoriasis.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PSORS1C3 Gene

Genomics for PSORS1C3 Gene

Regulatory Elements for PSORS1C3 Gene

Enhancers for PSORS1C3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around PSORS1C3 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the PSORS1C3 gene promoter:

Genomic Location for PSORS1C3 Gene

Chromosome:
6
Start:
31,173,735 bp from pter
End:
31,177,899 bp from pter
Size:
4,165 bases
Orientation:
Minus strand

Genomic View for PSORS1C3 Gene

Genes around PSORS1C3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PSORS1C3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PSORS1C3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for PSORS1C3 Gene

Post-translational modifications for PSORS1C3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PSORS1C3 Gene

Domains & Families for PSORS1C3 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PSORS1C3 Gene

Function for PSORS1C3 Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PSORS1C3 Gene

Localization for PSORS1C3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PSORS1C3 Gene

Pathways & Interactions for PSORS1C3 Gene

SuperPathways for PSORS1C3 Gene

No Data Available

Interacting Proteins for PSORS1C3 Gene

Gene Ontology (GO) - Biological Process for PSORS1C3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PSORS1C3 Gene

Drugs & Compounds for PSORS1C3 Gene

(1) Drugs for PSORS1C3 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Allopurinol Approved Pharma 133
genes like me logo Genes that share compounds with PSORS1C3: view

Transcripts for PSORS1C3 Gene

mRNA/cDNA for PSORS1C3 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PSORS1C3 Gene

Psoriasis susceptibility 1 candidate 3 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PSORS1C3 Gene

No ASD Table

Relevant External Links for PSORS1C3 Gene

GeneLoc Exon Structure for
PSORS1C3
ECgene alternative splicing isoforms for
PSORS1C3

Expression for PSORS1C3 Gene

mRNA expression in normal human tissues for PSORS1C3 Gene

mRNA differential expression in normal tissues according to GTEx for PSORS1C3 Gene

This gene is overexpressed in Bladder (x7.8) and Pancreas (x6.0).

NURSA nuclear receptor signaling pathways regulating expression of PSORS1C3 Gene:

PSORS1C3

SOURCE GeneReport for Unigene cluster for PSORS1C3 Gene:

Hs.670091
genes like me logo Genes that share expression patterns with PSORS1C3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for PSORS1C3 Gene

Orthologs for PSORS1C3 Gene

Evolution for PSORS1C3 Gene

ENSEMBL:
Gene Tree for PSORS1C3 (if available)
TreeFam:
Gene Tree for PSORS1C3 (if available)

No data available for Orthologs for PSORS1C3 Gene

Paralogs for PSORS1C3 Gene

No data available for Paralogs for PSORS1C3 Gene

Variants for PSORS1C3 Gene

Sequence variations from dbSNP and Humsavar for PSORS1C3 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs885701 -- 31,176,123(-) GACTT(C/T)GGTGG intron-variant
rs885702 -- 31,176,022(-) AGGAG(C/T)GGAGG intron-variant
rs887464 -- 31,178,143(-) ATACC(A/G)ATGTG upstream-variant-2KB
rs887465 -- 31,175,875(-) ACTGT(C/G)ATGGC intron-variant
rs887466 -- 31,175,734(-) GGAAA(C/T)ACCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PSORS1C3 Gene

Variant ID Type Subtype PubMed ID
dgv1174e214 CNV gain 21293372
dgv1175e214 CNV gain 21293372
esv2731791 CNV deletion 23290073
esv2759414 CNV gain+loss 17122850
esv32635 CNV gain+loss 17666407
esv3411275 CNV duplication 20981092
esv3608531 CNV loss 21293372
esv3608532 CNV gain 21293372
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1144137 CNV deletion 24896259
nsv428140 CNV gain+loss 18775914
nsv525933 CNV loss 19592680
nsv601264 CNV loss 21841781
nsv601481 CNV loss 21841781

Relevant External Links for PSORS1C3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PSORS1C3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PSORS1C3 Gene

Disorders for PSORS1C3 Gene

MalaCards: The human disease database

(2) MalaCards diseases for PSORS1C3 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
psoriasis susceptibility 1
  • psoriasis 1
psoriasis
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for PSORS1C3

Genetic Association Database (GAD)
PSORS1C3
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PSORS1C3
genes like me logo Genes that share disorders with PSORS1C3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PSORS1C3 Gene

Publications for PSORS1C3 Gene

  1. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. (PMID: 21051598) . … Zhao M. (Science 2010) 3 46 65
  2. Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes. (PMID: 16965413) Chang Y.T. … Tsai S.F. (Br. J. Dermatol. 2006) 3 46 65
  3. HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3. (PMID: 15848982) Holm S.J. … O'Brien K.P. (Acta Derm. Venereol. 2005) 3 46 65
  4. A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. (PMID: 21912425) Tohkin M. … Ikezawa Z. (Pharmacogenomics J. 2013) 3 65
  5. A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. (PMID: 23266558) Yamazaki K. … Kubo M. (Gastroenterology 2013) 3 65

Products for PSORS1C3 Gene

Sources for PSORS1C3 Gene

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