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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PSMF1 Gene

protein-coding   GIFtS: 58
GCID: GC20P001041

Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31)

Microbiology & Infectious Diseases Congress
  Search for PSMF1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31)1 2
Proteasome Inhibitor HP131 Subunit1 2
hPI312 3
PI312
Proteasome Inhibitor PI31 Subunit2

External Ids:    HGNC: 95711   Entrez Gene: 94912   Ensembl: ENSG000001258187   UniProtKB: Q925303   

Export aliases for PSMF1 gene to outside databases

Previous GC identifers: GC20P001087 GC20P001088


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PSMF1 Gene:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes,
a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are
composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a
base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase
subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in
an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome,
the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the
activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified
for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for PSMF1 Gene: 
PSMF1 (proteasome (prosome, macropain) inhibitor subunit 1 (PI31)) is a protein-coding gene. Among its related super-pathways are Regulation of APC/C activators between G1/S and early anaphase and Mitotic Anaphase. GO annotations related to this gene include protein binding and endopeptidase inhibitor activity.

UniProtKB/Swiss-Prot: PSMF1_HUMAN, Q92530
Function: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and
peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome
regulatory proteins PA700 and PA28

Gene Wiki entry for PSMF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NT_011387.8  NC_018931.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PSMF1 gene promoter:
         NRSF form 1   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): PSMF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PSMF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PSMF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

PSMF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PSMF1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P001041:  view genomic region     (about GC identifiers)

Start:
1,093,906 bp from pter      End:
1,149,022 bp from pter
Size:
55,117 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PSMF1_HUMAN, Q92530 (See protein sequence)
Recommended Name: Proteasome inhibitor PI31 subunit  
Size: 271 amino acids; 29817 Da
Subunit: Monomer (Probable)
1 PDB 3D structure from and Proteopedia for PSMF1:
2VT8 (3D)    
Secondary accessions: A0AVQ9 D3DVW3 Q9H4I1

Explore the universe of human proteins at neXtProt for PSMF1: NX_Q92530

Explore proteomics data for PSMF1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92530

  • PSMF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PSMF1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_006805.2  NP_848693.2  

    ENSEMBL proteins: 
     ENSP00000371324   ENSP00000246015   ENSP00000338039   ENSP00000396547   ENSP00000401404  
     ENSP00000327704   ENSP00000371323  
    Reactome Protein details: Q92530
    Human Recombinant Protein Products for PSMF1: 
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    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol TAS--
    GO:0005839proteasome core complex NAS10764772

    PSMF1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    PSM: Proteasome (prosome, macropain) subunits

    2 InterPro protein domains:
     IPR021625 Inhibitor_PI31
     IPR013886 PI31_Prot_Reg

    Graphical View of Domain Structure for InterPro Entry Q92530

    ProtoNet protein and cluster: Q92530

    1 Blocks protein domain: IPB013886 PI31 proteasome regulator

    UniProtKB/Swiss-Prot: PSMF1_HUMAN, Q92530
    Similarity: Belongs to the proteasome inhibitor PI31 family


    PSMF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PSMF1_HUMAN, Q92530
    Function: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and
    peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome
    regulatory proteins PA700 and PA28

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004866endopeptidase inhibitor activity NAS10764772
    GO:0005515protein binding IPI16713569
         
    PSMF1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PSMF1:
     Synthetic lethal with Ras 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for PSMF1 About   (see all 15)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1CDK-mediated phosphorylation and removal of Cdc6
    APC/C:Cdc20 mediated degradation of mitotic proteins0.94
    SCF(Skp2)-mediated degradation of p27/p210.89
    Cdc20:Phospho-APC/C mediated degradation of Cyclin A0.94
    Removal of licensing factors from origins0.89
    CDK-mediated phosphorylation and removal of Cdc60.94
    Regulation of DNA replication0.89
    Regulation of activated PAK-2p34 by proteasome mediated degradation0.94
    Cyclin E associated events during G1/S transition 0.89
    2M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    3Metabolism of mRNA
    Metabolism of RNA0.92
    Metabolism of mRNA0.92
    4Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    5Antigen processing: Ubiquitination & Proteasome degradation
    Antigen processing: Ubiquitination & Proteasome degradation0.83
    Class I MHC mediated antigen processing & presentation0.83

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5/74        Reactome Pathways for PSMF1 (see all 74)
        Orc1 removal from chromatin
    CDK-mediated phosphorylation and removal of Cdc6
    ER-Phagosome pathway
    CDT1 association with the CDC6:ORC:origin complex
    Autodegradation of the E3 ubiquitin ligase COP1


    1         Kegg Pathway  (Kegg details for PSMF1):
        Proteasome


    PSMF1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PSMF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/133 Interacting proteins for PSMF1 (Q925301, 2, 3 ENSP000003277044) via UniProtKB, MINT, STRING, and/or I2D (see all 133)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBFOX1Q9NWB11, 3, ENSP000003091174EBI-945916,EBI-945906 I2D: score=2 STRING: ENSP00000309117
    CD2BP2O954002, 3, ENSP000003049034MINT-62651 MINT-62663 I2D: score=2 STRING: ENSP00000304903
    RHOXF2Q9BQY43, ENSP000003604414I2D: score=4 STRING: ENSP00000360441
    BEND7Q8N7W23, ENSP000003457734I2D: score=3 STRING: ENSP00000345773
    CCDC85BQ158343, ENSP000003116954I2D: score=3 STRING: ENSP00000311695
    About this table

    Gene Ontology (GO): 5/23 biological process terms (GO ID links to tree view) (see all 23):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000082G1/S transition of mitotic cell cycle TAS--
    GO:0000209protein polyubiquitination TAS--
    GO:0000278mitotic cell cycle TAS--
    GO:0002474antigen processing and presentation of peptide antigen via MHC class I TAS--
    GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS--

    PSMF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PSMF1

    Search CenterWatch for drugs/clinical trials and news about PSMF1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PSMF1 gene (3 alternative transcripts): 
    NM_006814.3  NM_178578.2  NM_178579.1  

    Unigene Cluster for PSMF1:

    Proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
    Hs.471917  [show with all ESTs]
    Unigene Representative Sequence: NM_006814
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381899 ENST00000479715 ENST00000246015(uc010zpp.2) ENST00000335877(uc002wen.4)
    ENST00000478004 ENST00000484891(uc002wep.4) ENST00000435720 ENST00000438768
    ENST00000333082(uc010zpo.2 uc002wel.4) ENST00000381898
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    SwitchGear 3'UTR luciferase reporter plasmidPSMF1 3' UTR sequence
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    Additional mRNA sequence: 

    AF055032.1 AK294134.1 AK300667.1 AK302164.1 BC029836.1 BC126127.1 BC126462.1 D88378.1 

    24/28 DOTS entries (see all 28):

    DT.455109  DT.91773500  DT.100841453  DT.95268312  DT.120811472  DT.101959133  DT.120811443  DT.100841442 
    DT.97779331  DT.100841440  DT.100841447  DT.95268867  DT.40132530  DT.95268311  DT.120811527  DT.210795 
    DT.100841454  DT.120811513  DT.319527  DT.100841451  DT.120811447  DT.120811474  DT.120811502  DT.99983196 

    24/541 AceView cDNA sequences (see all 541):

    NM_178578 AA121765 AA311323 AI492323 BQ217517 BU735176 AI669520 BM696664 
    AA418014 BG680804 BM875493 BX114789 AA011302 BI494661 BM706095 AA418971 
    BX483501 AI185624 CR592856 AW473385 BX089168 T35281 CD676032 AI684395 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for PSMF1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b · 11c
    SP1:                                      -                       -     -     -                                             
    SP2:                                      -           -     -     -     -     -     -           -     -                     
    SP3:                                      -                       -     -     -                 -     -                     
    SP4:                                                              -     -     -                                             
    SP5:                                                                    -     -                                             


    ECgene alternative splicing isoforms for PSMF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PSMF1 expression in normal human tissues (normalized intensities)      PSMF1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGCCGGTTT
    PSMF1 Expression
    About this image


    PSMF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 5 entries
             Proerythroblasts Hematopoietic Bone Marrow
             bone marrow cd34+   
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 2 entries
             umbilical cord reticulocytes   
     
     Ovary (Reproductive System)
             oocyte   
     
     Spinal Cord (Nervous System)
             motor neurons   

    See PSMF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PSMF1

    SOURCE GeneReport for Unigene cluster: Hs.471917
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PSMF1 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Psmf11 , 5 proteasome (prosome, macropain) inhibitor subunit 11, 5 86.47(n)1
    83.76(a)1
      2 (74.83 cM)5
    2287691  NM_212446.11  NP_997611.11 
     1517158125 
    chicken
    (Gallus gallus)
    Aves PSMF11 proteasome (prosome, macropain) inhibitor subunit 1 more 64.33(n)
    62.36(a)
      430115  NM_001031582.1  NP_001026753.1 
    lizard
    (Anolis carolinensis)
    Reptilia PSMF16
    proteasome (prosome, macropain) inhibitor subunit ...
    55(a)
    1 ↔ 1
    GL343346.1(665827-681383)
    zebrafish
    (Danio rerio)
    Actinopterygii psmf11 proteasome (prosome, macropain) inhibitor subunit 1 56.09(n)
    51.66(a)
      436820  NM_001002547.2  NP_001002547.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG89791 CG8979 42.95(n)
    33.33(a)
      36277  NM_165854.1  NP_725092.1 


    ENSEMBL Gene Tree for PSMF1 (if available)
    TreeFam Gene Tree for PSMF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1240 SNPs in PSMF1 are shown (see all 1240)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1859071901,2
    --1091931(+) GAGGCA/GGAGGT 1 -- us2k10--------
    rs1436696481,2
    C--1091958(+) CGTGCC/TACTGT 1 -- us2k10--------
    rs1910576521,2
    --1091984(+) ATAGAA/GCAACA 1 -- us2k10--------
    rs72677371,2
    C,F--1092010(+) aaaTCA/Gtatat 1 -- us2k11Minor allele frequency- G:0.04NA 120
    rs1160562511,2
    F--1092011(+) AATCAT/GATATA 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs789822611,2
    C--1092144(+) CCTCAC/TACTTC 1 -- us2k10--------
    rs1409170821,2
    --1092341(+) ATGCTA/GGGGAA 1 -- us2k10--------
    rs130456281,2
    C,F,H--1092441(+) taagaC/Tgtaaa 1 -- us2k17Minor allele frequency- T:0.03EA NS NA 398
    rs60777681,2
    C,F,H--1092456(+) taaaaC/Ttcttg 1 -- us2k119Minor allele frequency- T:0.22NS EA NA WA CSA 2337
    rs759916611,2
    F--1092555(+) AATCAG/AGCAAA 1 -- us2k11Minor allele frequency- A:0.01NA 120

    HapMap Linkage Disequilibrium report for PSMF1 (1093906 - 1149022 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for PSMF1 (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2722058CNV Deletion23290073
    esv2524932CNV Deletion19546169
    dgv693e201CNV Deletion23290073
    esv2674425CNV Deletion23128226
    esv2722052CNV Deletion23290073
    dgv692e201CNV Deletion23290073
    esv2666587CNV Deletion23128226
    dgv694e201CNV Deletion23290073
    esv2722060CNV Deletion23290073
    esv2722059CNV Deletion23290073

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PSMF1 for disorders           About MalaCards

    PSMF1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PSMF1

    Export disorders for PSMF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PSMF1 gene, integrated from 9 sources (see all 63):
    (articles sorted by number of sources associating them with PSMF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    3. cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome. (PubMed id 10764772)1, 2 McCutchen-Maloney S.L.... DeMartino G.N. (2000)
    4. The proteasome-dependent proteolytic system. (PubMed id 10363639)1, 3 Tanahashi N....Tanaka K. (1999)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9491 HGNC: 9571 AceView: PSMF1 Ensembl:ENSG00000125818 euGenes: HUgn9491
    ECgene: PSMF1 Kegg: 9491 H-InvDB: PSMF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PSMF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PSMF1 gene:
    Search GeneIP for patents involving PSMF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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