Aliases for PSMA4 Gene
External Ids for PSMA4 Gene
Previous GeneCards Identifiers for PSMA4 Gene
This gene encodes a core alpha subunit of the 20S proteosome, which is a highly ordered ring-shaped structure composed of four rings of 28 non-identical subunits. Proteasomes cleave peptides in an ATP- and ubiquitin-dependent manner. [provided by RefSeq, Aug 2016]
GeneCards Summary for PSMA4 Gene
PSMA4 (Proteasome Subunit Alpha 4) is a Protein Coding gene. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis and Interleukin-3, 5 and GM-CSF signaling. GO annotations related to this gene include endopeptidase activity and threonine-type endopeptidase activity.
UniProtKB/Swiss-Prot for PSMA4 Gene
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.