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PSKH1 Gene

protein-coding   GIFtS: 58
GCID: GC16P067927

Protein Serine Kinase H1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Protein Serine Kinase H11 2 3
PSK-H12 3
EC 2.7.11.13 8
Serine/Threonine-Protein Kinase H12
EC 2.7.118

External Ids:    HGNC: 95291   Entrez Gene: 56812   Ensembl: ENSG000001597927   OMIM: 1770155   UniProtKB: P118013   

Export aliases for PSKH1 gene to outside databases

Previous GC identifers: GC16P058622 GC16P068304 GC16P067662 GC16P067703 GC16P066484 GC16P053800


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PSKH1 Gene:
PSKH1 (protein serine kinase H1) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity. An important paralog of this gene is PNCK.

UniProtKB/Swiss-Prot: KPSH1_HUMAN, P11801
Function: May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role
in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and
pre-mRNA processing

Gene Wiki entry for PSKH1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010498.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the PSKH1 gene promoter:
         SRF   NF-1/L   NF-1   SRF (504 AA)   SREBP-1c   CUTL1   SREBP-1b   PPAR-alpha   HEN1   SREBP-1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPSKH1 promoter sequence
   Search Chromatin IP Primers for PSKH1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PSKH1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

PSKH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PSKH1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P067927:  view genomic region     (about GC identifiers)

Start:
67,927,175 bp from pter      End:
67,963,581 bp from pter
Size:
36,407 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KPSH1_HUMAN, P11801 (See protein sequence)
Recommended Name: Serine/threonine-protein kinase H1  
Size: 424 amino acids; 48035 Da
Subunit: Homodimer
Secondary accessions: Q9NY19

Explore the universe of human proteins at neXtProt for PSKH1: NX_P11801

Explore proteomics data for PSKH1 at MOPED

Post-translational modifications: 

  • Autophosphorylated on serine residues1
  • Myristoylated. Required for membrane association. Prerequisite for palmitoylation to occur1
  • Palmitoylated1
  • Modification sites at neXtProt
  • Selected DME Specific Peptides for PSKH1 (P11801) (see all 20)
     YIAPEVL  VVRVEHR  GGELFDR  LKPENLL 


    See PSKH1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006733.1  
    ENSEMBL proteins: 
     ENSP00000291041  

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    antibodies-online proteins for PSKH1 (5 products) 

     
    antibodies-online peptides for PSKH1

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    antibodies-online antibodies for PSKH1 (19 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: protein serine kinase H1
    PSK family

    Selected InterPro protein domains (see all 6):
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry P11801

    ProtoNet protein and cluster: P11801

    UniProtKB/Swiss-Prot: KPSH1_HUMAN, P11801
    Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family
    Similarity: Contains 1 protein kinase domain


    Find genes that share domains with PSKH1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KPSH1_HUMAN, P11801
    Function: May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role
    in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and
    pre-mRNA processing
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein
    Enzyme regulation: Activity depends on Ca(2+) concentration

         Genatlas biochemistry entry for PSKH1:
    protein serine/kinase of unknown function

         Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with PSKH1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for PSKH1:
     Decreased focal adhesion (FA)   Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PSKH1
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    hsa-mir-149-5p (MIRT045428), hsa-mir-124-3p (MIRT022912)

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    Selected qRT-PCR Assays for microRNAs that regulate PSKH1 (see all 53):
    hsa-miR-194* hsa-miR-3678-3p hsa-miR-136 hsa-miR-330-5p hsa-miR-15a hsa-miR-503 hsa-miR-759 hsa-miR-652
    SwitchGear 3'UTR luciferase reporter plasmidPSKH1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PSKH1

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    Addgene plasmids for PSKH1 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KPSH1_HUMAN, P11801: Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus
    speckle. Endoplasmic reticulum membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Cytoplasm. Note=Localized in
    the brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like
    presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely
    in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase
    cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering
    to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and
    palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the
    interaction with Golgi membranes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    endoplasmic reticulum5
    golgi apparatus5
    nucleus5
    plasma membrane5
    cytosol3
    mitochondrion2

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005794Golgi apparatus IEA--
    GO:0005815microtubule organizing center IEA--
    GO:0005886plasma membrane IEA--

    Find genes that share ontologies with PSKH1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PSKH1 About    
    See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    mRNA processing0.44


    1 BioSystems Pathway for PSKH1
        mRNA processing



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PSKH1
    Interactions:

        Search GeneGlobe Interaction Network for PSKH1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for PSKH1 (P118011, 3 ENSP000002910414) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDC6Q997413, ENSP000002097284I2D: score=2 STRING: ENSP00000209728
    SNTA1Q134243I2D: score=1 
    HSP90AB1P082381EBI-3922781,EBI-352572
    RDH13ENSP000002918924STRING: ENSP00000291892
    RAD1ENSP000003408794STRING: ENSP00000340879
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----

    Find genes that share ontologies with PSKH1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PSKH1 (KPSH1)

    2 HMDB Compounds for PSKH1    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PSKH1 gene: 
    NM_006742.2  

    Unigene Cluster for PSKH1:

    Protein serine kinase H1
    Hs.513683  [show with all ESTs]
    Unigene Representative Sequence: BC062616
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000570631(uc010cet.2) ENST00000291041(uc002euv.3) ENST00000575198

    miRNA
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    hsa-miR-194* hsa-miR-3678-3p hsa-miR-136 hsa-miR-330-5p hsa-miR-15a hsa-miR-503 hsa-miR-759 hsa-miR-652
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    Additional mRNA sequence: 

    AJ272212.1 AK309272.1 BC021584.1 BC037560.1 BC062616.1 M14504.1 

    5 DOTS entries:

    DT.441944  DT.100751697  DT.97796543  DT.121615060  DT.95243517 

    Selected AceView cDNA sequences (see all 104):

    BF445737 BC021584 BQ924724 BQ222417 AI475805 BM855080 CD672632 BG742657 
    BU845833 BX284009 AI611121 AI203230 AI560478 BM476791 BM714417 BU848773 
    BC062616 BM856744 AI885803 AI436134 AI004013 AL527037 BG769288 CR619744 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PSKH1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCTGTGGAT
    PSKH1 Expression
    About this image

    PSKH1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PSKH1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513683

    UniProtKB/Swiss-Prot: KPSH1_HUMAN, P11801
    Tissue specificity: Expressed in all tissues and cell lines tested with the highest level of abundance in testis

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PSKH1 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Pskh11 , 5 protein serine kinase H11, 5 88.36(n)1
    97.64(a)1
      8 (53.06 cM)5
    2446311  NM_173432.21  NP_775608.11 
     1059004415 
    chicken
    (Gallus gallus)
    Aves PSKH11 protein serine kinase H1 81.54(n)
    89.26(a)
      415658  NM_001277682.1  NP_001264611.1 
    lizard
    (Anolis carolinensis)
    Reptilia PSKH16
    protein serine kinase H1
    89(a)
    1 ↔ 1
    GL343295.1(499113-515390)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.149872 Xenopus laevis transcribed sequence with strong similarity more 77.16(n)    CB942682.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc44h102 Transcribed sequence with moderate similarity to protein more 79.88(n)    57050119 
    worm
    (Caenorhabditis elegans)
    Secernentea R06A10.41 , 3 protein kinase3
    R06A10.41
    42(a)3
    54.36(n)1
    47.39(a)1
      I(1090070-1095795)3
    1716881  NM_058419.41  NP_490820.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes KSP1(YHR082C)4 Ser/thr protein kinase; nuclear translocation required more   --   8(271548-268459) 856482  NP_011950.1 
    rice
    (Oryza sativa)
    Liliopsida Os.58792 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 78.17(n)    AK102308.1 


    ENSEMBL Gene Tree for PSKH1 (if available)
    TreeFam Gene Tree for PSKH1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PSKH1 gene
    PNCK2  CAMK1G2  PSKH22  DCX2  DCLK22  CAMK2A2  CAMK1D2  DCLK12  
    CAMK42  CAMK2D2  DCLK32  CAMKV2  CAMK2G2  CAMK2B2  CAMK12  
    Selected SIMAP similar genes for PSKH1 using alignment to 1 protein entry:     KPSH1_HUMAN(see all similar genes):
    CAMK1D    PSKH2    CAMK1    PNCK    CAMK1G    CAMK4
    CAMKV    DCLK2    MGC45428    DCLK1    MELK    CAMK2B
    CAMK2G    CAMK2A    PRKAA1    RPS6KA6    CAMK2D    DAPK1

    Find genes that share paralogs with PSKH1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for PSKH1
    PGOHUM00000235222


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PSKH1 (see all 640)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1478318061,2
    --67925397(+) CTGGGC/TCTCCC 1 -- us2k10--------
    rs735945561,2
    C,F--67925435(+) GCACCG/ACGCTG 1 -- us2k12Minor allele frequency- A:0.18WA NA 238
    rs1165120271,2
    C,F--67925449(+) CACCAT/CTGTTC 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1890257551,2
    --67925634(+) GCACAA/GTGGTG 1 -- us2k10--------
    rs1413318891,2
    --67925663(+) TACTCA/GGGAGG 1 -- us2k10--------
    rs1160806551,2
    F--67925824(+) AAAATT/CAACCG 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs100837701,2
    A--67925903(+) gggagA/Gcagag 1 -- us2k10--------
    rs100837711,2
    A--67925915(+) ttgcaA/Gtgagc 1 -- us2k10--------
    rs1813749801,2
    --67926005(+) CTACAC/TAAAAT 1 -- us2k10--------
    rs1469680791,2
    C--67926226(+) TTGGTC/TAGACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PSKH1 (67927175 - 67963581 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for PSKH1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670395CNV Deletion23128226
    esv2591720CNV Deletion19546169
    nsv906813CNV Loss21882294
    nsv1844CNV Loss18451855
    esv21655CNV Loss19812545
    nsv524363CNV Loss19592680
    nsv906814CNV Loss21882294
    nsv522852CNV Gain19592680
    nsv442402CNV CNV18776908

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 177015    OMIM disorders: --


    Find genes that share disorders with PSKH1           About GenesLikeMe

    Genetic Association Database (GAD): PSKH1

    Export disorders for PSKH1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PSKH1 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with PSKH1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutants of the protein serine kinase PSKH1 disassemble the Golgi apparatus. (PubMed id 14644153)1, 2, 9 Brede G.... Prydz H. (Exp. Cell Res. 2003)
    2. Biological, clinical and population relevance of 95 loci for blood lipids. (PubMed id 20686565)1, 4 Teslovich T.M....Kathiresan S. (Nature 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. PSKH1, a novel splice factor compartment-associated serine kinase. (PubMed id 12466556)1, 2 Brede G.... Prydz H. (Nucleic Acids Res. 2002)
    5. Characterization of PSKH1, a novel human protein serine kinase with centrosomal, Golgi, and nuclear localization. (PubMed id 11087665)1, 2 Brede G.... Prydz H. (Genomics 2000)
    6. A tight cluster of five unrelated human genes on chromosome 16q22.1. (PubMed id 8268911)1, 3 Larsen F.... Prydz H. (Hum. Mol. Genet. 1993)
    7. Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family. (PubMed id 2948189)1, 2 Hanks S.K. (Proc. Natl. Acad. Sci. U.S.A. 1987)
    8. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (Nature 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5681 HGNC: 9529 AceView: PSKH1 Ensembl:ENSG00000159792 euGenes: HUgn5681
    ECgene: PSKH1 H-InvDB: PSKH1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PSKH1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PSKH1 gene:
    Search GeneIP for patents involving PSKH1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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