Aliases for PSIP1 Gene
External Ids for PSIP1 Gene
Previous HGNC Symbols for PSIP1 Gene
Previous GeneCards Identifiers for PSIP1 Gene
GeneCards Summary for PSIP1 Gene
PSIP1 (PC4 And SFRS1 Interacting Protein 1) is a Protein Coding gene. Diseases associated with PSIP1 include Hiv-1. Among its related pathways are Activation of cAMP-Dependent PKA and GPCR Pathway. GO annotations related to this gene include poly(A) RNA binding and RNA polymerase II transcription coactivator activity. An important paralog of this gene is HDGFRP2.
UniProtKB/Swiss-Prot for PSIP1 Gene
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.