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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PSG1 Gene

protein-coding   GIFtS: 53
GCID: GC19M043348

Pregnancy Specific Beta-1-Glycoprotein 1


(Previous symbol: PSBG1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Pregnancy Specific Beta-1-Glycoprotein 11 2     PSGGA2 3
PSBG11 2 3 5     CD66 Antigen-Like Family Member F2 3
B1G12 3 5     SP12 5
Fetal Liver Non-Specific Cross-Reactive Antigen 1/22 3     CD66f2
Pregnancy-Specific Beta-1 Glycoprotein C/D2 3     DHFRP22
Pregnancy-Specific Glycoprotein 12 3     PBG12
FL-NCA-1/22 3     PSGIIA2
PS-beta-C/D2 3     Pregnancy-Specific B-1 Glycoprotein2
PS-beta-G-12 3     Pregnancy-Specific Beta-1-Glycoprotein 12
PSBG-12 3     CD66f Antigen3
PSG952 3     

External Ids:    HGNC: 95141   Entrez Gene: 56692   Ensembl: ENSG000002319247   OMIM: 1763905   UniProtKB: P114643   

Export aliases for PSG1 gene to outside databases

Previous GC identifers: GC19M044018 GC19M043762 GC19M048024 GC19M048062 GC19M048063 GC19M047923 GC19M039800


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PSG1 Gene:
The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that
support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of
the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne
et al., 1976 (PubMed 971765)). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988
(PubMed 3257488); Streydio et al., 1988 (PubMed 3260773)).(supplied by OMIM, Oct 2009)

GeneCards Summary for PSG1 Gene: 
PSG1 (pregnancy specific beta-1-glycoprotein 1) is a protein-coding gene. Diseases associated with PSG1 include factor vii deficiency, and gestational trophoblastic neoplasm. An important paralog of this gene is PSG9.

Gene Wiki entry for PSG1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PSG1 gene promoter:
         AREB6   c-Myb   Pax-2   Pax-2a   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPSG1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PSG1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PSG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.2

PSG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PSG1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M043348:  view genomic region     (about GC identifiers)

Start:
43,370,613 bp from pter      End:
43,383,974 bp from pter
Size:
13,362 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PSG1_HUMAN, P11464 (See protein sequence)
Recommended Name: Pregnancy-specific beta-1-glycoprotein 1 precursor  
Size: 419 amino acids; 47223 Da
Subcellular location: Secreted (Potential)
Developmental stage: PSBG are produced in high quantity during pregnancy
Secondary accessions: O75236 P11462 P11463 Q15231 Q15241 Q15243 Q16660 Q6ICR4 Q9P1W5 Q9UQ79
Alternative splicing: 4 isoforms:  P11464-1   P11464-2   P11464-3   P11464-4   

Explore the universe of human proteins at neXtProt for PSG1: NX_P11464

Explore proteomics data for PSG1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P11464

  • PSG1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PSG1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001171754.1  NP_001171755.1  NP_008836.2  

    ENSEMBL proteins: 
     ENSP00000413041   ENSP00000472284   ENSP00000472610   ENSP00000385386   ENSP00000308970  
     ENSP00000244296   ENSP00000470690   ENSP00000469575  

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    Cloud-Clone Corp. Proteins for PSG1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    PSG1 for ontologies           About GeneDecksing



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    Assay Products for PSG1: 
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    Cloud-Clone Corp. ELISAs for PSG1 
    Cloud-Clone Corp. CLIAs for PSG1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing
    VSET: Immunoglobulin superfamily / V-set domain containing

    5 InterPro protein domains:
     IPR003598 Ig_sub2
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry P11464

    ProtoNet protein and cluster: P11464

    2 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: PSG1_HUMAN, P11464
    Similarity: Belongs to the immunoglobulin superfamily. CEA family
    Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    PSG1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for PSG1:
    pregnancy specific beta-1-glycoprotein 1,expressed by placental syncytiotrophoblasts,unknown
    function,carcinoembryonic antigen (CEA family),immunoglobulin superfamily

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    PSG1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PSG1 
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    miRNA
    Products:
        
    miRTarBase miRNAs that target PSG1:
    hsa-mir-124 (MIRT002660), hsa-mir-29b (MIRT000445), hsa-mir-218 (MIRT004246)

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    SwitchGear 3'UTR luciferase reporter plasmidPSG1 3' UTR sequence
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PSG1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PSG1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for PSG1 (P114643 ENSP000002442964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UTP14AQ9BVJ63, ENSP000003779444I2D: score=3 STRING: ENSP00000377944
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007565female pregnancy TAS1572651

    PSG1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PSG1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PSG1

    4 Novoseek inferred chemical compound relationships for PSG1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    oestriol 57 2 1694994 (1), 10416969 (1)
    progesterone 4.08 2 8567857 (1), 9740458 (1)
    estradiol 0 5 9219458 (5)
    zinc 0 2 11352651 (1)

    Search CenterWatch for drugs/clinical trials and news about PSG1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PSG1 gene (3 alternative transcripts): 
    NM_001184825.1  NM_001184826.1  NM_006905.2  

    Unigene Cluster for PSG1:

    Pregnancy specific beta-1-glycoprotein 1
    Hs.709192  [show with all ESTs]
    Unigene Representative Sequence: AK056754
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000436291(uc002ovb.3 uc002ovc.3 uc002ova.2 uc002ouz.2)
    ENST00000602039 ENST00000595124 ENST00000595356 ENST00000403380 ENST00000312439
    ENST00000244296(uc002oug.1 uc002oun.3 uc002ovd.1) ENST00000597058
    ENST00000595930 ENST00000601456 ENST00000601073
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PSG1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate PSG1
    SwitchGear 3'UTR luciferase reporter plasmidPSG1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for PSG1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PSG1
    Clone
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    OriGene clones in human, mouse for PSG1 (see all 14)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): PSG1 (NM_001184826)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PSG1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PSG1
    Sirion Biotech Customized lentivirus for stable overexpression of PSG1 
                         Customized lentivirus expression plasmids for stable overexpression of PSG1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PSG1
    OriGene qSTAR qPCR primer pairs in human, mouse for PSG1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PSG1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PSG1

    Additional mRNA sequence: 

    AK056754.1 AK300152.1 AK300206.1 AK311491.1 BC022338.1 BC058285.1 CR450329.1 J04539.1 
    M17908.1 M17909.1 M20879.1 M20881.1 M21822.1 M25385.1 M33663.1 M33664.1 
    M34715.1 M37397.1 

    24/122 DOTS entries (see all 122):

    DT.91785493  DT.100764684  DT.101973962  DT.121424134  DT.121424052  DT.100764233  DT.121424151  DT.121424059 
    DT.87078483  DT.100884390  DT.102844095  DT.121424719  DT.100041222  DT.100829135  DT.100884372  DT.100762520 
    DT.121424263  DT.100884331  DT.121424364  DT.121424479  DT.121424596  DT.100884388  DT.121424266  DT.121424824 

    24/93 AceView cDNA sequences (see all 93):

    CR600097 CR611664 BC058285 CR622475 NM_182707 CR621768 CR613770 CR612366 
    BC022338 CR620325 CR600148 CR609859 CR605150 CR609951 CR626276 BQ024077 
    M20879 CR612067 CR609860 CR614168 CR450329 CR612139 CR601994 CR603734 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PSG1 expression in normal human tissues (normalized intensities)      PSG1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCACCTTT
    PSG1 Expression
    About this image


    PSG1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Decidua-derived mesenchymal cells
             placenta   
     
     Epidermis (Integumentary System)
             Detroit 551
     
     Uterus (Reproductive System)
             endometrial endothelial cell   
     
     Mesenchymal Stem Cells (Muscoskeletal System)
             Decidua-derived mesenchymal cells
     
     Fibroblast
             Detroit 551

    See PSG1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PSG1

    SOURCE GeneReport for Unigene cluster: Hs.709192
        SABiosciences Custom PCR Arrays for PSG1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PSG1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for PSG1 (if available)
    TreeFam Gene Tree for PSG1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PSG1 gene
    PSG92  PSG82  CEACAM42  CEACAM52  PSG112  PSG32  CEACAM72  CEACAM212  
    PSG52  PSG62  ENSG000002678812  CEACAM82  CEACAM12  CEACAM62  CEACAM182  PSG22  
    CEACAM162  PSG42  PSG72  CEACAM32  
    18/25 SIMAP similar genes for PSG1 using alignment to 14 protein entries:     PSG1_HUMAN (see all proteins) (see all similar genes):
    DHFRP2    PSG    PSG2    PSG8    PSG11    PSGII
    PSG5    PSG4    PSG3    PSG7    PSG6    CEA
    PSG9    CEACAM8    CEACAM7    CEACAM3    CEACAM6    CEACAM1

    PSG1 for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for PSG1
    PGOHUM00000250578 PGOHUM00000234341 PGOHUM00000234344 PGOHUM00000259342


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/827 SNPs in PSG1 are shown (see all 827)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs58281531,2
    C--39813729(+) cacag-/ACAC  
      ACACAC
    acaca
    3 -- us2k10--------
    rs601897741,2
    C--43370124(+) TCTCCA/GTTGGA 2 -- ds50010--------
    rs116702371,2
    C,F,H--43370213(+) GTCTGC/TTAAGG 2 -- ds500110Minor allele frequency- T:0.02NS EA NA 1174
    rs1876602171,2
    --43370221(+) AGGCAA/TTGCCA 2 -- ds50010--------
    rs1150696131,2
    F--43370364(+) TTGCAG/ATGGAC 2 -- ds50011Minor allele frequency- A:0.14WA 118
    rs1455863861,2
    --43370366(+) GCAGTA/GGACTG 2 -- ds50010--------
    rs1169874861,2
    C,F--43370389(+) GGATGC/TCAGGT 2 -- ds50011Minor allele frequency- T:0.01NA 120
    rs1435120031,2
    --43370395(+) CAGGTA/GTCCCA 2 -- ds50010--------
    rs1921934321,2
    --43370396(+) AGGTAC/TCCCAT 2 -- ds50010--------
    rs1140455651,2
    F--43370442(+) ATGGGC/TTTGTA 2 -- ds50011Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for PSG1 (43370613 - 43383974 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/74 variations for PSG1 (see all 74):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv15e196CNV Deletion17116639
    esv2422471CNV Deletion17116639
    esv2718597CNV Deletion23290073
    dgv565e201CNV Deletion23290073
    esv2668472CNV Deletion23128226
    esv2663048CNV Deletion23128226
    dgv564e201CNV Deletion23290073
    esv2718595CNV Deletion23290073
    esv2718598CNV Deletion23290073
    nsv471409CNV Duplication19718026

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PSG1
    DNA2.0 Custom Variant and Variant Library Synthesis for PSG1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 176390    OMIM disorders: --

    15 diseases for PSG1:    About MalaCards
    factor vii deficiency    gestational trophoblastic neoplasm    trophoblastic neoplasm    germinoma
    down syndrome    choriocarcinoma    eclampsia    transitional cell carcinoma
    pre-eclampsia    basal cell carcinoma    infertility    esophagitis
    alcoholism    lung cancer    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for PSG1:
    Gestational trophoblastic neoplasm

    PSG1 for disorders           About GeneDecksing

    10/18 Novoseek inferred disease relationships for PSG1 gene (see all 18)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hydatidiform mole 52.4 2 2364798 (2)
    down syndrome 50.1 10 2146876 (3), 7925075 (2), 7528054 (1), 1387478 (1) (see all 7)
    gestational trophoblastic disease 49.3 1 1699189 (1)
    carcinoma large cell 45.8 1 7590693 (1)
    trisomy 39.4 9 10416969 (4), 7528054 (2), 1387478 (1)
    choriocarcinoma 31.8 1 8403104 (1)
    preeclampsia 31.4 8 14678084 (4), 12457454 (2), 12648442 (1), 19911417 (1)
    adenocarcinoma 26.7 4 7703564 (1), 7590693 (1), 9337537 (1), 9511851 (1)
    pregnancy ectopic 25.7 2 2364798 (2)
    lung carcinoma 20.3 3 9511851 (2), 7590693 (1)


    Export disorders for PSG1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PSG1 gene, integrated from 9 sources (see all 98):
    (articles sorted by number of sources associating them with PSG1)
        Utopia: connect your pdf to the dynamic
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    1. Linkage of two human pregnancy-specific beta 1-glycoprotein genes: one is associated with hydatidiform mole. (PubMed id 2377620)1, 2, 9 Leslie K.K.... Chou J.Y. (1990)
    2. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Carcinoembryonic antigen gene family members in submandibular salivary gland: demonstration of pregnancy-specific glycoproteins by cDNA cloning. (PubMed id 2350345)1, 2 Zoubir F.... Hammarstroem S. (1990)
    5. Carcinoembryonic antigen gene family: molecular cloning of cDNA for a PS-beta-G/FL-NCA glycoprotein with a novel domain arrangement. (PubMed id 2735907)1, 2 Khan W.N. and Hammarstroem S. (1989)
    6. cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver. (PubMed id 2783133)1, 2 Zimmermann W.A.... Thompson J.A. (1989)
    7. Molecular cloning and expression of cDNA for a carcinoembryonic antigen-related fetal liver glycoprotein. (PubMed id 2541441)1, 2 Khan W.N.... Hammarstroem S. (1989)
    8. Characterization of cDNA encoding human pregnancy-specific beta 1- glycoprotein from placenta and extraplacental tissues and their comparison with carcinoembryonic antigen. (PubMed id 3180995)1, 2 Chan W.-Y.... Shupert W.L. (1988)
    9. Isolation and characterization of complementary DNAs encoding human pregnancy-specific beta 1-glycoprotein. (PubMed id 3257488)1, 2 Watanabe S. and Chou J.Y. (1988)
    10. The human pregnancy-specific beta 1-glycoprotein (PS beta G) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family. (PubMed id 3260773)1, 2 Streydio C.... Vassart G. (1988)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5669 HGNC: 9514 AceView: PSG1 Ensembl:ENSG00000231924 euGenes: HUgn5669
    ECgene: PSG1 H-InvDB: PSG1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PSG1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PSG1 gene:
    Search GeneIP for patents involving PSG1

    GeneCards and IP:
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