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PSD2 Gene

protein-coding   GIFtS: 49
GCID: GC05P139175

Pleckstrin And Sec7 Domain Containing 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Pleckstrin And Sec7 Domain Containing 21 2
Pleckstrin Homology And SEC7 Domain-Containing Protein 22 3
6330404E20Rik2
PH And SEC7 Domain-Containing Protein 22
EC 2.5.1.68
EC 3.6.18

External Ids:    HGNC: 190921   Entrez Gene: 842492   Ensembl: ENSG000001460057   UniProtKB: Q9BQI73   

Export aliases for PSD2 gene to outside databases

Previous GC identifers: GC00U916997 GC05P139155 GC05P134332


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PSD2 Gene:
PSD2 (pleckstrin and Sec7 domain containing 2) is a protein-coding gene. Diseases associated with PSD2 include demyelinating polyneuropathy, and polyneuropathy. GO annotations related to this gene include phospholipid binding and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is PSD3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NT_029289.12  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PSD2 gene promoter:
         RP58   p53   MAZR   NF-kappaB   GATA-2   MZF-1   NF-kappaB2   c-Myb   MRF-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPSD2 promoter sequence
   Search Chromatin IP Primers for PSD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PSD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.2   Ensembl cytogenetic band:  5q31.2   HGNC cytogenetic band: 5q31.3

PSD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PSD2 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P139175:  view genomic region     (about GC identifiers)

Start:
139,175,406 bp from pter      End:
139,224,051 bp from pter
Size:
48,646 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PSD2_HUMAN, Q9BQI7 (See protein sequence)
Recommended Name: PH and SEC7 domain-containing protein 2  
Size: 771 amino acids; 84660 Da
Secondary accessions: D3DQD3 Q8N3J8

Explore the universe of human proteins at neXtProt for PSD2: NX_Q9BQI7

Explore proteomics data for PSD2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for PSD2 (Q9BQI7)
     KRTPRGR  AHRLARRL 


    See PSD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_115665.1  
    ENSEMBL proteins: 
     ENSP00000274710  

    PSD2 Human Recombinant Protein Products:

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    PSD2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. CLIAs for PSD2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PLEKH: Pleckstrin homology (PH) domain containing

    5 InterPro protein domains:
     IPR001849 Pleckstrin_homology
     IPR023394 Sec7_alpha_orthog
     IPR001605 PH_dom-spectrin-type
     IPR011993 PH_like_dom
     IPR000904 Sec7_dom

    Graphical View of Domain Structure for InterPro Entry Q9BQI7

    ProtoNet protein and cluster: Q9BQI7

    2 Blocks protein domains:
    IPB001605 Spectrin pleckstrin homology domain signature
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: PSD2_HUMAN, Q9BQI7
    Similarity: Belongs to the PSD family
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 SEC7 domain


    PSD2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Numbers (IUBMB): EC 3.6.12 EC 2.5.1.62

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005086ARF guanyl-nucleotide exchange factor activity IBA--
    GO:0005543phospholipid binding IEA--
         
    PSD2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PSD2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PSD2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PSD2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PSD2

    miRNA
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    Block miRNA regulation of human, mouse, rat PSD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PSD2 (see all 31):
    hsa-miR-1178 hsa-miR-4307 hsa-miR-199b-3p hsa-miR-631 hsa-miR-199a-3p hsa-miR-513a-5p hsa-miR-3129-5p hsa-miR-650
    SwitchGear 3'UTR luciferase reporter plasmidPSD2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PSD2
    Predesigned siRNA for gene silencing in human, mouse, rat PSD2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PSD2

    Clone
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    OriGene clones in human, mouse for PSD2 (see all 5)
    OriGene ORF clones in mouse, rat for PSD2
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    GenScript: all cDNA clones in your preferred vector: PSD2 (NM_032289)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PSD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PSD2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PSD2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PSD2_HUMAN, Q9BQI7: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005802NOT trans-Golgi network IBA--
    GO:0016021integral component of membrane IEA--
    GO:0030054cell junction IBA--
    GO:0030425dendrite IEA--
    GO:0043025neuronal cell body IEA--

    PSD2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PSD2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Endocytosis
    Endocytosis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for PSD2):
        Endocytosis


    PSD2 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PSD2
    Interactions:

        Search GeneGlobe Interaction Network for PSD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for PSD2 (Q9BQI73 ENSP000002747104) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PMS1P542773, ENSP000004064904I2D: score=1 STRING: ENSP00000406490
    PMS2P542783, ENSP000002658494I2D: score=1 STRING: ENSP00000265849
    CDK9ENSP000003623614STRING: ENSP00000362361
    CLUHENSP000003888724STRING: ENSP00000388872
    UNC50ENSP000003504094STRING: ENSP00000350409
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016192NOT vesicle-mediated transport IBA--
    GO:0030182neuron differentiation IBA--
    GO:0032012regulation of ARF protein signal transduction IEA--
    GO:0043087regulation of GTPase activity IBA--

    PSD2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PSD2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PSD2 gene: 
    NM_032289.2  

    Unigene Cluster for PSD2:

    Pleckstrin and Sec7 domain containing 2
    Hs.21963  [show with all ESTs]
    Unigene Representative Sequence: AL136559
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000274710(uc003leu.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PSD2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PSD2 (see all 31):
    hsa-miR-1178 hsa-miR-4307 hsa-miR-199b-3p hsa-miR-631 hsa-miR-199a-3p hsa-miR-513a-5p hsa-miR-3129-5p hsa-miR-650
    SwitchGear 3'UTR luciferase reporter plasmidPSD2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PSD2
    Predesigned siRNA for gene silencing in human, mouse, rat PSD2
    Clone
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    OriGene clones in human, mouse for PSD2 (see all 5)
    OriGene ORF clones in mouse, rat for PSD2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PSD2 (NM_032289)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PSD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PSD2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PSD2
    OriGene qSTAR qPCR primer pairs in human, mouse for PSD2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PSD2
      QuantiTect SYBR Green Assays in human, mouse, rat PSD2
      QuantiFast Probe-based Assays in human, mouse, rat PSD2

    Additional mRNA sequence: 

    AL136559.1 AL834268.1 BC038233.1 

    2 DOTS entries:

    DT.112778  DT.100666583 

    Selected AceView cDNA sequences (see all 65):

    AL834268 AL136559 AI858637 BC038233 Z42535 BE551621 F02053 Z39050 
    AA953847 AI990006 AI866630 F03540 NM_032289 Z42932 N62170 BE047813 
    BX431556 F09102 AW006116 BM690700 AI871275 N99410 AI657098 BE672141 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PSD2 expression in normal human tissues (normalized intensities)      PSD2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACTACTGTA
    PSD2 Expression
    About this image


    PSD2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Endothelial Cells Blood Brain Barrier
             Ventral/hypothalamic-like neurons
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Neurons
             Ventral/hypothalamic-like neurons
     
     Intermediate Mesoderm (Gastrulation Derivatives)
             Mesonephros
     
     Kidney (Urinary System)
             Metanephros
    PSD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PSD2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.21963
        Custom PCR Arrays for PSD2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PSD2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for PSD2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Psd21 , 5 pleckstrin and Sec7 domain containing 21, 5 85.71(n)1
    88.76(a)1
      18 (19.34 cM)5
    740021  NM_028707.31  NP_082983.31 
     359648305 
    chicken
    (Gallus gallus)
    Aves PSD21 pleckstrin and Sec7 domain containing 2 73.54(n)
    79.68(a)
      427605  XM_004944743.1  XP_004944800.1 
    lizard
    (Anolis carolinensis)
    Reptilia PSD26
    pleckstrin and Sec7 domain containing 2
    64(a)
    1 ↔ 1
    4(78657817-78742172)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5571991 PH and SEC7 domain-containing protein 2-like 69.18(n)
    72.18(a)
      557199  XM_680213.2  XP_685305.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Efa66
    Efa6 pleckstrin and Sec7 domain containing
    18(a)
    1 → many
    3R(18413477-18434564)
    worm
    (Caenorhabditis elegans)
    Secernentea efa-66
    Protein EFA-6, isoform a
    24(a)
    1 → many
    IV(12605696-12614723) WBGene00013223
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes GEA26
    GEA16
    Guanine nucleotide exchange factor for ADP ribosyl...
    Guanine nucleotide exchange factor for ADP ribosyl...
    7(a)
    7(a)
    many ↔ many
    many ↔ many
    V(111421-115800) YEL022W
    X(486586-490812) YJR031C


    ENSEMBL Gene Tree for PSD2 (if available)
    TreeFam Gene Tree for PSD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PSD2 gene
    PSD32  GBF12  PSD2  PSD42  
    3 SIMAP similar genes for PSD2 using alignment to 1 protein entry:     PSD2_HUMAN:
    PSD3    PSD4    PSD

    PSD2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PSD2 (see all 1067)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs21941411,2
    C,F,A,H--139173441(-) CAGTCC/TCCCTC 1 -- us2k1 trp315Minor allele frequency- T:0.16NS EA NA WA 2208
    rs2004407191,2
    --139173441(+) AGGGG-/AGACTG 1 -- us2k10--------
    rs1421397311,2
    --139173474(+) GAGGAA/GGTAGG 1 -- us2k10--------
    rs1512983611,2
    --139173624(+) GCAGGA/GGGGTA 1 -- us2k10--------
    rs732631321,2
    C,F--139173627(+) GGGGGG/TTAGAA 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1859232341,2
    --139173659(+) AGCTCC/TCTCTG 1 -- us2k10--------
    rs3701528751,2
    C--139173693(+) TGCAC-/AGAGAGT 1 -- us2k10--------
    rs756782211,2
    F--139173725(+) CTGCGG/ATAATG 1 -- us2k11Minor allele frequency- A:0.09WA 118
    rs743344661,2
    C,F--139173795(+) GTGCTC/TACAGA 1 -- us2k11Minor allele frequency- T:0.02EA 120
    rs1458805531,2
    C--139173819(+) GGATCA/GTGAGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PSD2 (139175406 - 139224051 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for PSD2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv882945CNV Loss21882294
    nsv882942CNV Loss21882294
    nsv830506CNV Loss17160897
    nsv519808CNV Loss19592680
    nsv471051CNV Gain18288195

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PSD2
    DNA2.0 Custom Variant and Variant Library Synthesis for PSD2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    4 diseases for PSD2:    About MalaCards
    demyelinating polyneuropathy    polyneuropathy    neuronitis    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for PSD2:
    Demyelinating polyneuropathy

    PSD2 for disorders           About GeneDecksing


    Export disorders for PSD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PSD2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with PSD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2. (PubMed id 17148452)1 Cannavo E....Jiricny J. (J. Biol. Chem. 2007)
    3. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    4. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (Nature 2004)
    7. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (Genome Res. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)1 Simpson J.C.... Wiemann S. (EMBO Rep. 2000)
    10. DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)1 Hartley J.L....Brasch M.A. (Genome Res. 2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84249 HGNC: 19092 AceView: PSD2 Ensembl:ENSG00000146005 euGenes: HUgn84249
    ECgene: PSD2 Kegg: 84249 H-InvDB: PSD2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for PSD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PSD2 gene:
    Search GeneIP for patents involving PSD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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