Aliases for PSD Gene
External Ids for PSD Gene
Previous GeneCards Identifiers for PSD Gene
This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
GeneCards Summary for PSD Gene
PSD (Pleckstrin And Sec7 Domain Containing) is a Protein Coding gene. Diseases associated with PSD include Branch Retinal Artery Occlusion. Among its related pathways are Endocytosis. GO annotations related to this gene include signal transducer activity and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is PSD2.
UniProtKB/Swiss-Prot for PSD Gene
Guanine nucleotide exchange factor for ARF6. Induces cytoskeletal remodeling (By similarity).