Aliases for PRTN3 Gene
External Ids for PRTN3 Gene
Previous GeneCards Identifiers for PRTN3 Gene
GeneCards Summary for PRTN3 Gene
PRTN3 (Proteinase 3) is a Protein Coding gene. Diseases associated with PRTN3 include Wegener Granulomatosis and Rapidly Progressive Glomerulonephritis. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cytokine Signaling in Immune system. GO annotations related to this gene include enzyme binding and serine-type peptidase activity. An important paralog of this gene is ELANE.
UniProtKB/Swiss-Prot for PRTN3 Gene
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.