Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PRTG Gene

protein-coding   GIFtS: 51
GCID: GC15M055903

Protogenin

(Previous name: protogenin homolog (Gallus gallus))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
protogenin1 2     Member 51
Protogenin Homolog (Gallus Gallus)1 2     IGDCC52
Protein Shen-Dan2 3     Immunoglobulin Superfamily, DCC Subclass, Member 52
DCC Subclass1     shen-dan2
Immunoglobulin Superfamily1     

External Ids:    HGNC: 263731   Entrez Gene: 2836592   Ensembl: ENSG000001664507   OMIM: 6132615   UniProtKB: Q2VWP73   

Export aliases for PRTG gene to outside databases

Previous GC identifers: GC15M053700 GC15M032727


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for PRTG Gene:
PRTG (protogenin) is a protein-coding gene. Diseases associated with PRTG include facial neuralgia, and trigeminal neuralgia. An important paralog of this gene is CHL1.

UniProtKB/Swiss-Prot: PRTG_HUMAN, Q2VWP7
Function: May play a role in anteroposterior axis elongation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000015.10  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PRTG gene promoter:
         AML1a   GATA-3   STAT5A   Nkx2-5   E47   C/EBPalpha   SRY   FOXO4   HFH-1   Hand1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRTG promoter sequence
   Search Chromatin IP Primers for PRTG

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRTG


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21.3   Ensembl cytogenetic band:  15q21.3   HGNC cytogenetic band: 15q21.3

PRTG Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRTG gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M055903:  view genomic region     (about GC identifiers)

Start:
55,903,738 bp from pter      End:
56,035,288 bp from pter
Size:
131,551 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PRTG_HUMAN, Q2VWP7 (See protein sequence)
Recommended Name: Protogenin precursor  
Size: 1150 amino acids; 127076 Da
Sequence caution: Sequence=BAC05355.1; Type=Erroneous initiation;
Secondary accessions: Q8N7D8

Explore the universe of human proteins at neXtProt for PRTG: NX_Q2VWP7

Explore proteomics data for PRTG at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn90, Asn488, Asn630, Asn986
  • Modification sites at PhosphoSitePlus

  • See PRTG Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_776175.2  
    ENSEMBL proteins: 
     ENSP00000373937   ENSP00000453160   ENSP00000453335   ENSP00000452760  

    PRTG Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for PRTG (Protogenin)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for PRTG
    OriGene Protein Over-expression Lysate for PRTG
    OriGene MassSpec for PRTG
    OriGene Custom Protein Services for PRTG
    GenScript Custom Purified and Recombinant Proteins Services for PRTG
    Novus Biologicals PRTG Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PRTG

    PRTG Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for PRTG (Protogenin)
    OriGene Antibodies for PRTG
    OriGene Custom Antibody Services for PRTG
    Novus Biologicals PRTG Antibodies
    Abcam antibodies for PRTG
    Cloud-Clone Corp. Antibodies for PRTG
    ThermoFisher Antibodies for PRTG
    Search LSBio for Antibodies for PRTG

    PRTG Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PRTG
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PRTG
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PRTG
    Cloud-Clone Corp. CLIAs for PRTG


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    FN3: Fibronectin type III domain containing
    ISET: Immunoglobulin superfamily / I-set domain containing

    5 InterPro protein domains:
     IPR003598 Ig_sub2
     IPR003961 Fibronectin_type3
     IPR013098 Ig_I-set
     IPR013783 Ig-like_fold
     IPR007110 Ig-like_dom

    Graphical View of Domain Structure for InterPro Entry Q2VWP7

    ProtoNet protein and cluster: Q2VWP7

    1 Blocks protein domain: IPB003598 Immunoglobulin C-2 type

    UniProtKB/Swiss-Prot: PRTG_HUMAN, Q2VWP7
    Similarity: Belongs to the immunoglobulin superfamily. DCC family
    Similarity: Contains 5 fibronectin type-III domains
    Similarity: Contains 4 Ig-like (immunoglobulin-like) domains


    PRTG for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PRTG_HUMAN, Q2VWP7
    Function: May play a role in anteroposterior axis elongation (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    PRTG for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Prtg (no phenotypes)

    PRTG for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRTG
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PRTG

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRTG
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRTG

    miRNA
    Products:
        
    miRTarBase miRNAs that target PRTG:
    hsa-let-7b-5p (MIRT051907)

    Block miRNA regulation of human, mouse, rat PRTG using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PRTG (see all 235):
    hsa-miR-411* hsa-miR-579 hsa-miR-938 hsa-miR-3653 hsa-miR-138-2* hsa-miR-759 hsa-miR-149 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidPRTG 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PRTG
    Predesigned siRNA for gene silencing in human, mouse, rat PRTG

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PRTG

    Clone
    Products:
         
    OriGene clones in human, mouse for PRTG (see all 5)
    OriGene ORF clones in mouse, rat for PRTG
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRTG (NM_173814)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRTG
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRTG

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PRTG
    Browse ESI BIO Cell Lines and PureStem Progenitors for PRTG 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRTG


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    PRTG_HUMAN, Q2VWP7: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular2
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0016021integral component of membrane IEA--

    PRTG for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for PRTG About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Neural Crest Differentiation
    Neural Crest Differentiation


    1 BioSystems Pathway for PRTG
        Neural Crest Differentiation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRTG
    Interactions:

        Search GeneGlobe Interaction Network for PRTG

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--

    PRTG for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRTG



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for PRTG gene: 
    NM_173814.4  

    Unigene Cluster for PRTG:

    Protogenin
    Hs.130957  [show with all ESTs]
    Unigene Representative Sequence: NM_173814
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389286(uc002adg.3) ENST00000561465(uc002adh.3) ENST00000559842
    ENST00000561292 ENST00000558349
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PRTG using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PRTG (see all 235):
    hsa-miR-411* hsa-miR-579 hsa-miR-938 hsa-miR-3653 hsa-miR-138-2* hsa-miR-759 hsa-miR-149 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidPRTG 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PRTG
    Predesigned siRNA for gene silencing in human, mouse, rat PRTG
    Clone
    Products:
         
    OriGene clones in human, mouse for PRTG (see all 5)
    OriGene ORF clones in mouse, rat for PRTG
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRTG (NM_173814)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRTG
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRTG
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for PRTG
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRTG
      QuantiTect SYBR Green Assays in human, mouse, rat PRTG
      Search QuantiFast Probe-based Assays in human, mouse, rat PRTG

    Additional mRNA sequence: 

    AK023283.1 AK098622.1 AY630258.1 BC073967.1 

    11 DOTS entries:

    DT.91753885  DT.102824048  DT.102820947  DT.121071272  DT.121071244  DT.97795693  DT.121071247  DT.40128529 
    DT.95256719  DT.75120995  DT.75184754 

    4 AceView cDNA sequences:

    BX092588 CB142953 AI015076 BU175315 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    PRTG expression in normal human tissues (normalized intensities)      PRTG embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAAAAATGA
    PRTG Expression
    About this image


    PRTG expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
     
     Neural Ectoderm (Nervous System)    fully expand to see all 2 entries
             Spinal Neural Plate Cells Neural Plate
             Neural Plate
     
     NULL (Uncategorized)    fully expand to see all 2 entries
             Mesoderm-like cells
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Neural Tube (Nervous System)
             Prosencephalon
    PRTG Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRTG Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.130957
        Custom PCR Arrays for PRTG
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for PRTG
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRTG
    QuantiTect SYBR Green Assays in human, mouse, rat PRTG
    Search QuantiFast Probe-based Assays in human, mouse, rat PRTG
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRTG

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for PRTG gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prtg1 , 5 protogenin homolog (Gallus gallus)1, 5 84.82(n)1
    91.1(a)1
      9 (40.08 cM)5
    2354721  NM_175485.41  NP_780694.31 
     728068745 
    chicken
    (Gallus gallus)
    Aves PRTG1 protogenin 79.62(n)
    85.94(a)
      415407  NM_001030548.2  NP_001025719.1 
    lizard
    (Anolis carolinensis)
    Reptilia PRTG6
    protogenin
    76(a)
    1 ↔ 1
    AAWZ02039909(2843-6893)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia prtg1 protogenin 71.68(n)
    71.95(a)
      100496178  XM_004912700.1  XP_004912757.1 
    zebrafish
    (Danio rerio)
    Actinopterygii prtga1 protogenin homolog a (Gallus gallus) 63.07(n)
    64.29(a)
      563834  NM_001045030.1  NP_001038495.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cont6
    Contactin
    14(a)
    1 → many
    3R(207032-212741)


    ENSEMBL Gene Tree for PRTG (if available)
    TreeFam Gene Tree for PRTG (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for PRTG gene
    CHL12  NEO12  ROBO12  CNTN52  CNTN42  IGDCC42  NRCAM2  L1CAM2  
    ROBO22  CNTN22  CNTN62  NFASC2  CNTN32  DCC2  IGDCC32  ROBO32  
    CNTN12  
    11 SIMAP similar genes for PRTG using alignment to 4 protein entries:     PRTG_HUMAN (see all proteins):
    PXDN    ROBO3    CNTN5    IGDCC4    IGDCC3    PXDNL
    ROBO2    HMCN2    MUSK    PTPRS    DCC

    PRTG for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PRTG
    PGOHUM00000262134


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for PRTG (see all 2920)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1435481151,2
    Cuntested155974628(+) ACAACA/GATAAT 2 R C mis10--------
    rs1875785871,2
    --55903268(+) AGTCCC/GCATTT 1 -- int10--------
    rs1925207121,2
    --55903299(+) TTTTTA/TTAAAA 1 -- int10--------
    rs1843917241,2
    --55903300(+) TTTTTA/TAAAAA 1 -- int10--------
    rs1905052591,2
    --55903301(+) TTTTTA/TAAAAA 1 -- int10--------
    rs1819952791,2
    --55903416(+) AAAATC/TTTAAT 1 -- int10--------
    rs1844596081,2
    --55903428(+) CTAAAA/GAAAAA 1 -- int10--------
    rs6037221,2
    C,F,H--55903501(+) TTAACT/CCCTGA 1 -- int117Minor allele frequency- C:0.02NS EA NA WA CSA 790
    rs5620861,2
    C,F,H--55903566(-) ACATTT/CACTAT 1 -- int116Minor allele frequency- C:0.08NS EA NA WA CSA 795
    rs1892074171,2
    --55903661(+) GTGAAA/GGCCAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for PRTG (55903738 - 56035288 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for PRTG:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833017CNV Loss17160897
    nsv457158CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PRTG
    DNA2.0 Custom Variant and Variant Library Synthesis for PRTG

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613261    OMIM disorders: --

    4 diseases for PRTG:    About MalaCards
    facial neuralgia    trigeminal neuralgia    thyroiditis    cerebritis


    PRTG for disorders           About GeneDecksing

    Genetic Association Database (GAD): PRTG
    Human Genome Epidemiology (HuGE) Navigator: PRTG (1 document)

    Export disorders for PRTG gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for PRTG gene integrated from 10 sources:
    (articles sorted by number of sources associating them with PRTG)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association of ADHD and the Protogenin gene in the chromosome 15q21.3 reading disabilities linkage region. (PubMed id 19076634)1, 4, 9 Wigg K.G....Barr C.L. (Genes Brain Behav. 2008)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Identification of protogenin, a novel immunoglobulin superfamily gene expressed during early chick embryogenesis. (PubMed id 15922677)1, 9 Toyoda R....Watanabe Y. (Gene Expr. Patterns 2005)
    4. MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin. (PubMed id 24007463)1 Song J....Jin E.J. (Cell Commun. Signal 2013)
    5. Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. (PubMed id 23648065)1 Low S.K....Nakamura Y. (Cancer Sci. 2013)
    6. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 283659 HGNC: 26373 AceView: FLJ25756.1 Ensembl:ENSG00000166450 euGenes: HUgn283659
    ECgene: PRTG H-InvDB: PRTG

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for PRTG Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PRTG gene:
    Search GeneIP for patents involving PRTG

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Antibodies for PRTG (Protogenin)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Recombinant/Natural Proteins for PRTG (Protogenin)   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for PRTG   OriGene RNAi products in human, mouse, rat for PRTG  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for PRTG  
     OriGene MassSpec something-or-other for PRTG   OriGene clones in human, mouse for PRTG  
     OriGene qSTAR qPCR primer pairs in human, mouse for PRTG   OriGene Purified Protein for PRTG  
     OriGene ORF clones in mouse, rat for PRTG   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PRTG   OriGene Custom Protein Services for PRTG  

     
     
     Block miRNA regulation of human, mouse, rat PRTG using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PRTG
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRTG Predesigned siRNA for gene silencing in human, mouse, rat PRTG
     Search QuantiFast Probe-based Assays in human, mouse, rat PRTG QuantiTect SYBR Green Assays in human, mouse, rat PRTG
     Custom PCR Arrays for PRTG Search Chromatin IP Primers for PRTG
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRTG  Search GeneGlobe Interaction Network for PRTG
     Regulatory tfbs in PRTG promoter
     GenScript Custom Purified and Recombinant Proteins Services for PRTG GenScript cDNA clones with any tag delivered in your preferred vector for PRTG
     GenScript Custom Assay Services for PRTG GenScript Custom overexpressing Cell Line Services for PRTG
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for PRTG
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     PRTG antibodies
     PRTG lysates
     Antibodies for PRTG
     See all of Abcam's Antibodies, Kits and Proteins for PRTG
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for PRTG
     Antibodies for PRTG
     ELISAs for PRTG
     CLIAs for PRTG



     Browse ESI BIO Cell Lines and PureStem Progenitors for PRTG
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRTG
     SwitchGear 3'UTR luciferase reporter plasmids for PRTG
     SwitchGear Promoter luciferase reporter plasmids for PRTG
     ThermoFisher Antibodies for PRTG
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRTG
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRTG
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PRTG
     Search LSBio for Antibodies for PRTG
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PRTG gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4