PRTFDC1 Gene
protein-coding GIFtS: 50
GCID: GC10M025177
|
|
phosphoribosyl transferase domain containing 1
| |
Aliases for PRTFDC1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Phosphoribosyl Transferase Domain Containing 11 2 | | HHGP1 2 3 | | Phosphoribosyltransferase Domain-Containing Protein 12 | | EC 2.4.28 | | EC 2.4.2.88 |
Export aliases for PRTFDC1 gene to outside databasesPrevious GC identifers: GC10M025141 GC10M024799 |
Summaries for PRTFDC1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: PRDC1_HUMAN, Q9NRG1Function: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP andalpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage
|
Genomic Views for PRTFDC1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008705.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the PRTFDC1 gene promoter: MZF-1 Spz1 AML1a HFH-1 FOXO3 FOXO3a AP-4 E47 FOXO3b Other transcription factors
Search SABiosciences Chromatin IP Primers for PRTFDC1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRTFDC1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10p12.1 Ensembl cytogenetic band: 10p12.1 HGNC cytogenetic band: 10p12.31PRTFDC1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M025177: view genomic region
(about GC identifiers)
Start:
|
25,137,554 bp from pter |
End:
|
25,241,533 bp from pter |
Size:
|
103,980 bases |
Orientation:
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minus strand |
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Proteins for PRTFDC1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: PRDC1_HUMAN, Q9NRG1 (See
protein sequence)Recommended Name: Phosphoribosyltransferase domain-containing protein 1 Size: 225 amino acids; 25674 Da
Subunit: Homodimer
Caution: Lacks the conserved active site Asp and has no significant phosphoribosyltransferase activity
Sequence caution: Sequence=BAD93029.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for PRTFDC1:2JBH (3D)
 
Secondary accessions: B7Z1Z3 Q53HA7 Q59EL9 Q5VV18 Q5VV20Alternative splicing: 3 isoforms: Q9NRG1-1 Q9NRG1-2 Q9NRG1-3 Explore the universe of human proteins at neXtProt for PRTFDC1: NX_Q9NRG1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRG1 2 DME Specific Peptides for PRTFDC1 (Q9NRG1)
PRTFDC1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_064585.1 ENSEMBL proteins: ENSP00000318602 ENSP00000365558 ENSP00000365556 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
IBA | -- |
PRTFDC1 for ontologies About GeneDecksing
PRTFDC1 Antibody Products: Assay Products for PRTFDC1: |
Protein
Domains / Families for PRTFDC1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PRTFDC1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NRG1ProtoNet protein and cluster: Q9NRG1 UniProtKB/Swiss-Prot: PRDC1_HUMAN, Q9NRG1Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family |
Function for PRTFDC1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: PRDC1_HUMAN, Q9NRG1Function: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP andalpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvageEnzyme Numbers (IUBMB): EC 2.4.2.82 EC 2.4.22
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRTFDC1 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRTFDC1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PRTFDC1 (NM_020200) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PRTFDC1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRTFDC1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRTFDC1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0000287 | magnesium ion binding |
TAS | -- | | GO:0004422 | NOT hypoxanthine phosphoribosyltransferase activity |
IDA | -- | | GO:0042803 | protein homodimerization activity |
IPI | -- |
PRTFDC1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for PRTFDC1:
|
Pathways & Interactions for PRTFDC1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRTFDC1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
 5/12 Interacting proteins for PRTFDC1 (Q9NRG12, 3 ENSP000003186024) via UniProtKB, MINT, STRING, and/or I2D (see all 12)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| FLAD1 | Q8NFF52, 3, ENSP000002921804 | MINT-66367 I2D:
score=5 STRING: ENSP00000292180 | | FAM86A | Q96G042, 3, ENSP000003985024 | MINT-67146 I2D:
score=4 STRING: ENSP00000398502 | | HPRT1 | P004922, 3, ENSP000002985564 | MINT-68331 I2D:
score=5 STRING: ENSP00000298556 | | STAT5A | P422292, 3, ENSP000003412084 | MINT-68247 I2D:
score=5 STRING: ENSP00000341208 | | NIF3L1 | Q9GZT82, 3, ENSP000003863944 | MINT-66143 I2D:
score=5 STRING: ENSP00000386394 | About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
PRTFDC1 for ontologies About GeneDecksing
|
Drugs & Compounds for PRTFDC1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for PRTFDC1 Search CenterWatch for drugs/clinical trials and news about PRTFDC1 / PRDC1 
|
Transcripts for PRTFDC1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for PRTFDC1 gene: NM_020200.5 Unigene Cluster for PRTFDC1: Phosphoribosyl transferase domain containing 1 Hs.405619 [show with all ESTs]Unigene Representative Sequence: NM_0202003 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000320152(uc001ise.1 uc010qdd.1 uc009xkm.1) ENST00000376378 ENST00000376376
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRTFDC1 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRTFDC1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PRTFDC1 (NM_020200) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PRTFDC1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRTFDC1  |
Additional cDNA sequence: AB209792.1 AF226056.1 AK021950.1 AK222674.1 AK294130.1 AK304055.1 AK309614.1 BC008662.2 8 DOTS entries: DT.409886 DT.75154558 DT.100774630 DT.91749750 DT.91749752 DT.121280446 DT.97807895 DT.121280444 24/108 AceView cDNA sequences (see all 108): AU120059 AL544876 AA007505 AW026416 AA557390 BX448610 AK021950 AV682666 BX440549 AA358233 BI768153 CR617937 CR596757 CR619546 NM_020200 BM821338 CK818776 BM831070 BC008662 BU151307 BM768969 BP362073 BM766205 BM823597 GeneLoc Exon Structure
|
Expression for PRTFDC1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PRTFDC1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See PRTFDC1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for PRTFDC1
SOURCE GeneReport for Unigene cluster: Hs.405619 SABiosciences Custom PCR Arrays for PRTFDC1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRTFDC1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat PRTFDC1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRTFDC1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRTFDC1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRTFDC1 |
Orthologs for PRTFDC1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for PRTFDC1 gene from 8/26 species (see all 26) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
PRTFDC11 |
phosphoribosyl transferase domain containing 1 |
78.35(n) 84.11(a) |
  |
420499 NM_001199585.1 NP_001186514.1 |
lizard (Anolis carolinensis) |
Reptilia |
PRTFDC16 |
-- |
80(a) |
1 ↔ 1 |
6(15226465-15260489) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.74092 |
Xenopus laevis transcribed sequence with weak similarity more |
75.41(n) |
  |
BX854233.1 |
zebrafish (Danio rerio) |
Actinopterygii |
hprt12 |
hypoxanthine guanine phosphoribosyltransferase-like |
75.72(n) |
  |
30765 BC047173.1 |
worm (Caenorhabditis elegans) |
Secernentea |
Y105E8B.56 |
Protein Y105E8B.5 |
46(a) |
1 → many |
I(14657344-14661403) |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
HGPT6 |
hypoxanthine phosphoribosyltransferase |
29(a) |
possible ortholog |
1(26987775-26989199) |
rice (Oryza sativa) |
Liliopsida |
-- |
phosphoribosyl transferase, putative, expressed |
23(a) |
possible ortholog |
5(4947656-4951852) |
E. coli (Escherichia coli) |
Gamma proteobacteria |
hpt6 |
hypoxanthine phosphoribosyltransferase |
30(a) |
possible ortholog |
Chromosome(141431-141967) |
Species with no ortholog for PRTFDC1
ENSEMBL Gene Tree for PRTFDC1 (if available) TreeFam Gene Tree for PRTFDC1 (if available)  |
Paralogs for PRTFDC1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for PRTFDC1 gene
- HPRT12
1 SIMAP similar gene for PRTFDC1 using alignment to 1 protein entry: PRDC1_HUMAN:HPRT1
PRTFDC1 for paralogs About GeneDecksing
|
Genomic Variants for PRTFDC1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 10 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for PRTFDC1 (25137554 - 25241533 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for PRTFDC1 1 Indel: 58434  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRTFDC1 |
|
Disorders
/ Diseases for PRTFDC1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PRTFDC1 for disorders About GeneDecksing
OMIM gene information: 610751
OMIM disorders: --
10 diseases for PRTFDC1: About MalaCardslesch-nyhan syndrome oral squamous cell carcinoma squamous cell carcinoma pneumonia carcinoma cerebritis tuberculosis malaria neuronitis mycobacterium tuberculosis 1 disease from the University of Copenhagen DISEASES database for PRTFDC1:Lesch-Nyhan syndrome Export disorders for PRTFDC1 gene to outside databases
|
Publications for PRTFDC1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PRTFDC1 gene, integrated from 9 sources (see all 15): (articles sorted by number of sources associating them with PRTFDC1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1. (PubMed id 21054786)1, 2 Welin M.... Nordlund P. (2010)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- PRTFDC1 is a genetic modifier of HPRT-deficiency in t he mouse. (PubMed id 21818316)1 Keebaugh A.C....Thomas J.W. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Gene duplication and inactivation in the HPRT gene family. (PubMed id 16928426)1 Keebaugh A.C....Thomas J.W. (2007)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation. (PubMed id 17599052)1 Suzuki E....Inazawa J. (2007)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for PRTFDC1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing PRTFDC1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PRTFDC1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PRTFDC1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for PRTFDC1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PRTFDC1 gene: Search GeneIP for patents involving PRTFDC1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for PRTFDC1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
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| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRTFDC1 |
|  |  |  | | | ThermoFisher Antibodies for PRTFDC1 |
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