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Aliases for PRSS41 Gene

Aliases for PRSS41 Gene

  • Protease, Serine 41 2 3 5
  • Testis Serine Protease 1 2 4
  • TESSP1 3 4
  • Testis-Specific Serine Protease 1 3
  • Protease, Serine, 41 3
  • EC 3.4.21.- 4
  • TESSP-1 4

External Ids for PRSS41 Gene

Previous GeneCards Identifiers for PRSS41 Gene

  • GC16P002851
  • GC16P002852
  • GC16P002815
  • GC16P002853
  • GC16P002854
  • GC16P002855
  • GC16P002856
  • GC16P002857

Summaries for PRSS41 Gene

GeneCards Summary for PRSS41 Gene

PRSS41 (Protease, Serine 41) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRSS41 Gene

Genomics for PRSS41 Gene

Regulatory Elements for PRSS41 Gene

Enhancers for PRSS41 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around PRSS41 on UCSC Golden Path with GeneCards custom track

Genomic Location for PRSS41 Gene

2,798,476 bp from pter
2,805,284 bp from pter
6,809 bases
Plus strand

Genomic View for PRSS41 Gene

Genes around PRSS41 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRSS41 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRSS41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRSS41 Gene

Proteins for PRSS41 Gene

  • Protein details for PRSS41 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative serine protease 41
    Protein Accession:

    Protein attributes for PRSS41 Gene

    318 amino acids
    Molecular mass:
    35078 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRSS41 Gene

Proteomics data for PRSS41 Gene at MOPED

Post-translational modifications for PRSS41 Gene

Other Protein References for PRSS41 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for PRSS41 Gene

Domains & Families for PRSS41 Gene

Gene Families for PRSS41 Gene

Suggested Antigen Peptide Sequences for PRSS41 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 peptidase S1 domain.
  • Belongs to the peptidase S1 family.
  • Contains 1 peptidase S1 domain.
  • Belongs to the peptidase S1 family.
genes like me logo Genes that share domains with PRSS41: view

Function for PRSS41 Gene

Enzyme Numbers (IUBMB) for PRSS41 Gene

Phenotypes for PRSS41 Gene

genes like me logo Genes that share phenotypes with PRSS41: view

Animal Model Products

No data available for Molecular function , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRSS41 Gene

Localization for PRSS41 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRSS41 Gene

Cell membrane; Lipid-anchor, GPI-anchor. Note=Localized in the plasma membrane of spermatogonia. Localized in intracellular compartment in spermatocytes, probably in the Golgi apparatus (By similarity). {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for PRSS41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043229 intracellular organelle ISS --
genes like me logo Genes that share ontologies with PRSS41: view

No data available for Subcellular locations from COMPARTMENTS for PRSS41 Gene

Pathways & Interactions for PRSS41 Gene

SuperPathways for PRSS41 Gene

No Data Available

Interacting Proteins for PRSS41 Gene

Gene Ontology (GO) - Biological Process for PRSS41 Gene


No data available for Pathways by source and SIGNOR curated interactions for PRSS41 Gene

Drugs & Compounds for PRSS41 Gene

No Compound Related Data Available

Transcripts for PRSS41 Gene

mRNA/cDNA for PRSS41 Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PRSS41 Gene

Protease, serine, 41:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PRSS41 Gene

No ASD Table

Relevant External Links for PRSS41 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PRSS41 Gene

mRNA expression in normal human tissues for PRSS41 Gene

mRNA differential expression in normal tissues according to GTEx for PRSS41 Gene

This gene is overexpressed in Testis (x31.9) and Minor Salivary Gland (x4.4).

Protein differential expression in normal tissues from HIPED for PRSS41 Gene

This gene is overexpressed in Lung (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRSS41 Gene

SOURCE GeneReport for Unigene cluster for PRSS41 Gene Hs.647401

genes like me logo Genes that share expression patterns with PRSS41: view

Protein tissue co-expression partners for PRSS41 Gene

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for PRSS41 Gene

Orthologs for PRSS41 Gene

This gene was present in the common ancestor of mammals.

Orthologs for PRSS41 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC617302 35
  • 72.18 (n)
  • 58.46 (a)
(Mus musculus)
Mammalia Prss41 35
  • 71.33 (n)
  • 64 (a)
Prss41 16
(Pan troglodytes)
Mammalia PRSS41 35
  • 98.42 (n)
  • 97.63 (a)
(Rattus norvegicus)
Mammalia Prss41 35
  • 69.47 (n)
  • 61.2 (a)
Species with no ortholog for PRSS41:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRSS41 Gene

Gene Tree for PRSS41 (if available)
Gene Tree for PRSS41 (if available)

Paralogs for PRSS41 Gene

genes like me logo Genes that share paralogs with PRSS41: view

No data available for Paralogs for PRSS41 Gene

Variants for PRSS41 Gene

Sequence variations from dbSNP and Humsavar for PRSS41 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
VAR_064369 -
rs4550448 -- 2,796,982(+) gcgcc(A/C)ccatg upstream-variant-2KB
rs736812 -- 2,804,871(-) GTGGG(C/T)GGGGC intron-variant
rs61578075 -- 2,801,535(+) TTGGT(A/G)ATGAC intron-variant
rs61747735 -- 2,799,495(+) CATCG(A/G)GTCTT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for PRSS41 Gene

Variant ID Type Subtype PubMed ID
nsv905152 CNV Loss 21882294
dgv793e1 CNV Complex 17122850
nsv905162 CNV Gain 21882294
nsv905165 CNV Loss 21882294
dgv2573n71 CNV Loss 21882294
nsv905169 CNV Loss 21882294
nsv905170 CNV Loss 21882294
nsv905173 CNV Loss 21882294

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for PRSS41 Gene

Disorders for PRSS41 Gene

Relevant External Links for PRSS41

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PRSS41 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRSS41 Gene

Publications for PRSS41 Gene

  1. Human and mouse proteases: a comparative genomic approach. (PMID: 12838346) Puente X.S. … Lopez-Otin C. (Nat. Rev. Genet. 2003) 2 3 4 67
  2. T-SP1: a novel serine protease-like protein predominantly expressed in testis. (PMID: 18844450) Neth P. … Jochum M. (Biol. Chem. 2008) 23

Products for PRSS41 Gene

Sources for PRSS41 Gene