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Aliases for PRSS41 Gene

Aliases for PRSS41 Gene

  • Protease, Serine, 41 2 3
  • Testis Serine Protease 1 2 4
  • TESSP1 3 4
  • Testis-Specific Serine Protease 1 3
  • Putative Serine Protease 41 3
  • EC 3.4.21.- 4
  • TESSP-1 4

External Ids for PRSS41 Gene

Previous GeneCards Identifiers for PRSS41 Gene

  • GC16P002851
  • GC16P002852
  • GC16P002815
  • GC16P002853
  • GC16P002854
  • GC16P002855
  • GC16P002856
  • GC16P002857

Summaries for PRSS41 Gene

GeneCards Summary for PRSS41 Gene

PRSS41 (Protease, Serine, 41) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRSS41 Gene

Genomics for PRSS41 Gene

Genomic Location for PRSS41 Gene

Start:
2,798,485 bp from pter
End:
2,805,132 bp from pter
Size:
6,648 bases
Orientation:
Plus strand

Genomic View for PRSS41 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PRSS41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRSS41 Gene

No data available for Regulatory Elements for PRSS41 Gene

Proteins for PRSS41 Gene

  • Protein details for PRSS41 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7RTY9-PRS41_HUMAN
    Recommended name:
    Putative serine protease 41
    Protein Accession:
    Q7RTY9
    Secondary Accessions:

    Protein attributes for PRSS41 Gene

    Size:
    318 amino acids
    Molecular mass:
    35078 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRSS41 Gene

Proteomics data for PRSS41 Gene at MOPED

Post-translational modifications for PRSS41 Gene

Other Protein References for PRSS41 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for PRSS41 Gene

Domains for PRSS41 Gene

Gene Families for PRSS41 Gene

HGNC:
  • PRSS :Serine peptidases / Serine peptidases

Suggested Antigen Peptide Sequences for PRSS41 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7RTY9

UniProtKB/Swiss-Prot:

PRS41_HUMAN :
  • Q7RTY9
Domain:
  • Contains 1 peptidase S1 domain.
Family:
  • Belongs to the peptidase S1 family.
genes like me logo Genes that share domains with PRSS41: view

Function for PRSS41 Gene

Enzyme Numbers (IUBMB) for PRSS41 Gene

Gene Ontology (GO) - Molecular Function for PRSS41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004252 serine-type endopeptidase activity IEA --
genes like me logo Genes that share ontologies with PRSS41: view

Phenotypes for PRSS41 Gene

GenomeRNAi human phenotypes for PRSS41:
genes like me logo Genes that share phenotypes with PRSS41: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for PRSS41 Gene

Localization for PRSS41 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRSS41 Gene

Cell membrane; Lipid-anchor, GPI-anchor. Note=Localized in the plasma membrane of spermatogonia. Localized in intracellular compartment in spermatocytes, probably in the Golgi apparatus (By similarity). {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for PRSS41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane ISS --
GO:0031225 anchored component of membrane IEA --
GO:0043229 intracellular organelle ISS --
genes like me logo Genes that share ontologies with PRSS41: view

No data available for Subcellular locations from COMPARTMENTS for PRSS41 Gene

Pathways for PRSS41 Gene

SuperPathways for PRSS41 Gene

No Data Available

Interacting Proteins for PRSS41 Gene

Gene Ontology (GO) - Biological Process for PRSS41 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with PRSS41: view

No data available for Pathways by source for PRSS41 Gene

Transcripts for PRSS41 Gene

mRNA/cDNA for PRSS41 Gene

(6) Selected AceView cDNA sequences:
(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PRSS41 Gene

Protease, serine, 41:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PRSS41

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for PRSS41
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRSS41 Gene

No ASD Table

Relevant External Links for PRSS41 Gene

GeneLoc Exon Structure for
PRSS41
ECgene alternative splicing isoforms for
PRSS41

Expression for PRSS41 Gene

mRNA expression in normal human tissues for PRSS41 Gene

mRNA differential expression in normal tissues according to GTEx for PRSS41 Gene

This gene is overexpressed in Testis (31.9) and Minor Salivary Gland (4.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for PRSS41 Gene

SOURCE GeneReport for Unigene cluster for PRSS41 Gene Hs.647401

genes like me logo Genes that share expressions with PRSS41: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for PRSS41 Gene

Orthologs for PRSS41 Gene

This gene was present in the common ancestor of mammals.

Orthologs for PRSS41 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PRSS41 35
  • 98.42 (n)
  • 97.63 (a)
cow
(Bos Taurus)
Mammalia LOC617302 35
  • 72.18 (n)
  • 58.46 (a)
mouse
(Mus musculus)
Mammalia Prss41 35
  • 71.33 (n)
  • 64 (a)
Prss41 16
rat
(Rattus norvegicus)
Mammalia Prss41 35
  • 69.47 (n)
  • 61.2 (a)
Species with no ortholog for PRSS41:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRSS41 Gene

ENSEMBL:
Gene Tree for PRSS41 (if available)
TreeFam:
Gene Tree for PRSS41 (if available)

Paralogs for PRSS41 Gene

genes like me logo Genes that share paralogs with PRSS41: view

No data available for Paralogs for PRSS41 Gene

Variants for PRSS41 Gene

Sequence variations from dbSNP and Humsavar for PRSS41 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs2335458 -- 2,796,843(+) ttttt(A/T)aattt upstream-variant-2KB
rs4550448 -- 2,796,982(+) gcgcc(A/C)ccatg upstream-variant-2KB
rs6500611 -- 2,797,511(+) tgatc(C/T)gccca upstream-variant-2KB
rs6500612 -- 2,797,516(+) tgccc(A/G)cctca upstream-variant-2KB
rs7195905 -- 2,797,324(+) agtgg(C/T)gcgat upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for PRSS41 Gene

Variant ID Type Subtype PubMed ID
nsv905152 CNV Loss 21882294
dgv793e1 CNV Complex 17122850
nsv905162 CNV Gain 21882294
nsv905165 CNV Loss 21882294
dgv2573n71 CNV Loss 21882294
nsv905169 CNV Loss 21882294
nsv905170 CNV Loss 21882294
nsv905173 CNV Loss 21882294

Relevant External Links for PRSS41 Gene

HapMap Linkage Disequilibrium report
PRSS41

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRSS41 Gene

Disorders for PRSS41 Gene

No disorders were found for PRSS41 Gene.

No data available for UniProtKB/Swiss-Prot for PRSS41 Gene

Publications for PRSS41 Gene

  1. Human and mouse proteases: a comparative genomic approach. (PMID: 12838346) Puente X.S. … Lopez-Otin C. (Nat. Rev. Genet. 2003) 2 3 4
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4
  3. A focal epilepsy and intellectual disability syndrome is due to a mutation in TBC1D24. (PMID: 20797691) Corbett M.A. … Gecz J. (Am. J. Hum. Genet. 2010) 4
  4. T-SP1: a novel serine protease-like protein predominantly expressed in testis. (PMID: 18844450) Neth P. … Jochum M. (Biol. Chem. 2008) 23

Products for PRSS41 Gene

Sources for PRSS41 Gene

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