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Aliases for PRSS37 Gene

Aliases for PRSS37 Gene

  • Protease, Serine, 37 2 3
  • Probable Inactive Trypsin-X2 3 4
  • TRYX2 3 4
  • Peptidase S1 Domain-Containing Protein LOC136242 3
  • Probable Inactive Serine Protease 37 3

External Ids for PRSS37 Gene

Summaries for PRSS37 Gene

GeneCards Summary for PRSS37 Gene

PRSS37 (Protease, Serine, 37) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is KLK12.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRSS37 Gene

Genomics for PRSS37 Gene

Genomic Location for PRSS37 Gene

Start:
141,836,278 bp from pter
End:
141,841,532 bp from pter
Size:
5,255 bases
Orientation:
Minus strand

Genomic View for PRSS37 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PRSS37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRSS37 Gene

No data available for Regulatory Elements for PRSS37 Gene

Proteins for PRSS37 Gene

  • Protein details for PRSS37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A4D1T9-PRS37_HUMAN
    Recommended name:
    Probable inactive serine protease 37
    Protein Accession:
    A4D1T9
    Secondary Accessions:
    • B2RPB5

    Protein attributes for PRSS37 Gene

    Size:
    235 amino acids
    Molecular mass:
    26445 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRSS37 Gene

Proteomics data for PRSS37 Gene at MOPED

Post-translational modifications for PRSS37 Gene

No Post-translational modifications

Other Protein References for PRSS37 Gene

No data available for DME Specific Peptides for PRSS37 Gene

Domains for PRSS37 Gene

Gene Families for PRSS37 Gene

HGNC:
  • PRSS :Serine peptidases / Serine peptidases

Protein Domains for PRSS37 Gene

Suggested Antigen Peptide Sequences for PRSS37 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A4D1T9

UniProtKB/Swiss-Prot:

PRS37_HUMAN
Domain:
  • Contains 1 peptidase S1 domain.:
    • A4D1T9
Family:
  • Belongs to the peptidase S1 family.:
    • A4D1T9
genes like me logo Genes that share domains with PRSS37: view

Function for PRSS37 Gene

Gene Ontology (GO) - Molecular Function for PRSS37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity --
GO:0004252 serine-type endopeptidase activity IEA --
genes like me logo Genes that share ontologies with PRSS37: view

Phenotypes for PRSS37 Gene

MGI mutant phenotypes for PRSS37:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with PRSS37: view

Animal Models for PRSS37 Gene

MGI Knock Outs for PRSS37:

No data available for Molecular function , Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targeting and HOMER Transcription for PRSS37 Gene

Localization for PRSS37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRSS37 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PRSS37 Gene COMPARTMENTS Subcellular localization image for PRSS37 gene
Compartment Confidence
extracellular 3
cytosol 1
lysosome 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for PRSS37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005634 nucleus IDA 21630459
genes like me logo Genes that share ontologies with PRSS37: view

Pathways for PRSS37 Gene

SuperPathways for PRSS37 Gene

No Data Available

Interacting Proteins for PRSS37 Gene

Gene Ontology (GO) - Biological Process for PRSS37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0007339 binding of sperm to zona pellucida IEA --
GO:0008152 metabolic process --
GO:0016477 cell migration IEA --
GO:0051604 protein maturation IEA --
genes like me logo Genes that share ontologies with PRSS37: view

No data available for Pathways by source for PRSS37 Gene

Transcripts for PRSS37 Gene

Unigene Clusters for PRSS37 Gene

Protease, serine, 37:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PRSS37 Gene

No ASD Table

Relevant External Links for PRSS37 Gene

GeneLoc Exon Structure for
PRSS37
ECgene alternative splicing isoforms for
PRSS37

Expression for PRSS37 Gene

mRNA expression in normal human tissues for PRSS37 Gene

mRNA differential expression in normal tissues according to GTEx for PRSS37 Gene

This gene is overexpressed in Testis (42.8).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for PRSS37 Gene

SOURCE GeneReport for Unigene cluster for PRSS37 Gene Hs.98947

genes like me logo Genes that share expressions with PRSS37: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for PRSS37 Gene

Orthologs for PRSS37 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PRSS37 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PRSS37 35
  • 99 (n)
  • 98.72 (a)
PRSS37 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia PRSS37 35
  • 84.33 (n)
  • 83.33 (a)
PRSS37 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PRSS37 35
  • 85.84 (n)
  • 85.84 (a)
PRSS37 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Prss37 35
  • 83.76 (n)
  • 82.91 (a)
Prss37 16
Prss37 36
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia PRSS37 36
  • 57 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Prss37 35
  • 83.48 (n)
  • 82.05 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
OneToMany
Species with no ortholog for PRSS37:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRSS37 Gene

ENSEMBL:
Gene Tree for PRSS37 (if available)
TreeFam:
Gene Tree for PRSS37 (if available)

Paralogs for PRSS37 Gene

Selected SIMAP similar genes for PRSS37 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with PRSS37: view

Variants for PRSS37 Gene

Sequence variations from dbSNP and Humsavar for PRSS37 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs3800990 -- 141,837,741(+) GTAGC(A/G)TCTCT intron-variant
rs3800991 -- 141,837,763(+) TTTCA(C/T)TCTCC intron-variant
rs3823668 -- 141,837,497(+) TGACC(G/T)GAGGC intron-variant
rs4545003 -- 141,841,980(+) AGTTT(C/G)TTAAA upstream-variant-2KB
rs6945661 -- 141,841,951(+) CTACA(C/T)TTTGT upstream-variant-2KB

Relevant External Links for PRSS37 Gene

HapMap Linkage Disequilibrium report
PRSS37
Human Gene Mutation Database (HGMD)
PRSS37

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PRSS37 Gene

Disorders for PRSS37 Gene

No disorders were found for PRSS37 Gene.

No data available for UniProtKB/Swiss-Prot for PRSS37 Gene

Publications for PRSS37 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for PRSS37 Gene

Sources for PRSS37 Gene

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