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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

PRSS35 Gene

protein-coding GIFtS: 47
GCID: GC06P084278

protease, serine, 35

(Previous name: chromosome 6 open reading frame 158 )
(Previous symbol: C6orf158)

Search for PRSS35
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Protease, Serine, 35¹ ²		Chromosome 6 Open Reading Frame 158¹
C6orf158¹ ² ³		Inactive Serine Protease 35²
DJ223E3.1¹		EC 3.4.21⁸
MGC46520¹		EC 3.4.21.4⁸

External Ids:	HGNC: 21387¹	Entrez Gene: 167681²	Ensembl: ENSG00000146250⁷	UniProtKB: Q8N3Z0³

Export aliases for PRSS35 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_007299.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the PRSS35 gene promoter:
TBP Cdc5 Evi-1 AREB6 PPAR-gamma1 POU2F1 FOXJ2 (long isoform) POU2F1a FOXJ2 PPAR-gamma2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PRSS35 promoter sequence

Search SABiosciences Chromatin IP Primers for PRSS35

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRSS35

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14.2 Ensembl cytogenetic band: 6q14.2 HGNC cytogenetic band: 6q14.2

PRSS35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRSS35 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06P084278: view genomic region (about GC identifiers)

Start:	84,222,194 bp from pter	End:	84,235,423 bp from pter
Size:	13,230 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PRS35_HUMAN, Q8N3Z0 (See protein sequence)

Recommended Name: Inactive serine protease 35 precursor

Size: 413 amino acids; 47098 Da

Subcellular location: Secreted (Potential)

Caution: Although related to peptidase S1 family, lacks the conserved active Ser residue in position 346 which is

replaced by a Thr, suggesting that it has no protease activity

Secondary accessions: A8K7B3 Q9BQP6

Explore the universe of human proteins at neXtProt for PRSS35: NX_Q8N3Z0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N3Z0

2 DME Specific Peptides for PRSS35 (Q8N3Z0)

VLTAAHC

DYDYALLEL

PRSS35 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001163894.1 NP_699193.2

ENSEMBL proteins:

ENSP00000358714 ENSP00000440870

Human Recombinant Protein Products:

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	Uscn Proteins for PRSS35

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005739	mitochondrion	IEA	--

PRSS35 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for PRSS35

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PRSS35 for domains About GeneDecksing

3 InterPro domains/families:

IPR001254 Peptidase_S1

IPR018114 Peptidase_S1_AS

IPR009003 Trypsin-like_Pept_dom

Graphical View of Domain Structure for InterPro Entry Q8N3Z0

ProtoNet protein and cluster: Q8N3Z0

2 Blocks protein families:

IPB001254 Serine protease

IPB001314 Chymotrypsin serine protease family (S1) signature

UniProtKB/Swiss-Prot: PRS35_HUMAN, Q8N3Z0

Similarity: Belongs to the peptidase S1 family

Similarity: Contains 1 peptidase S1 domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Enzyme Numbers (IUBMB): EC 3.4.21.4² EC 3.4.21²

miRNA Products:		OriGene 3'-UTR Clone: PRSS35 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRSS35
		8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate PRSS35 (see all 19):
		hsa-miR-125a-5p hsa-miR-4251 hsa-miR-1297 hsa-miR-629* hsa-miR-125b hsa-miR-376a* hsa-miR-548x hsa-miR-23a

		SwitchGear 3'UTR luciferase reporter plasmid: PRSS35 3' UTR sequence

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRSS35

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003824	catalytic activity	IEA	--
GO:0004252	serine-type endopeptidase activity	--	--

PRSS35 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for PRSS35:

G0/1 arrest

Increased G1 DNA content

Animal Models:
1 MGI phenotypic allele

for Prss35 (no phenotypes)

PRSS35 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for PRSS35

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for PRSS35 (ENSP00000358714⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269
ODF2L	ENSP00000359598⁴	STRING: ENSP00000359598

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PRSS35
Search CenterWatch for drugs/clinical trials and news about PRSS35 / PRS35

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PRSS35 gene (2 alternative transcripts):

NM_001170423.1 NM_153362.2

Unigene Cluster for PRSS35:

Protease, serine, 35

Hs.98381 [show with all ESTs]

Unigene Representative Sequence: NM_001170423

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000369700 ENST00000536636(uc010kbm.3 uc003pjz.3)

miRNA Products:		OriGene 3'-UTR Clone: PRSS35 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRSS35
		8/19 QIAGEN miScript miRNA Assays for microRNAs that regulate PRSS35 (see all 19):
		hsa-miR-125a-5p hsa-miR-4251 hsa-miR-1297 hsa-miR-629* hsa-miR-125b hsa-miR-376a* hsa-miR-548x hsa-miR-23a

		SwitchGear 3'UTR luciferase reporter plasmid: PRSS35 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRSS35

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRSS35 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRSS35 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): PRSS35 (NM_153362)
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRSS35
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRSS35

Additional cDNA sequence:

AK291928.1 AY358661.1 BC037170.1

3 DOTS entries:

DT.310830 DT.95338469 DT.100673865

24/28 AceView cDNA sequences (see all 28):

CR615063 AA702780 NM_153362 BC037170 AY358661 AA424028 AI266636 AA423988

AI424866 AI266634 AA424073 BX350107 AA445948 CA414746 BI552165 BI913028

AA483361 AL551286 AI271571 AA452037 BX389627 AA424003 AA453213 AA742931

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for PRSS35 About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b
SP1:
SP2:					-

ECgene alternative splicing isoforms for PRSS35

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PRSS35 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

PRSS35 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Atrioventricular Node

Atrioventricular Node Cells

Myocardium

Ovary

Primary Follicle

Granulosa Cells

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 5 LifeMap Cells

Name

Category

PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

Primitive streak-like cells (Generation of endode...)

Intervertebral disc (IVD) annulus fibrosus (AF) cells (Differentiation of s...)

Cartilage

HyStem+BMP4-induced SM30 cells (HyStem+BMP4 inductio...)

Adipose, Bone, Cartilage

See PRSS35 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PRSS35

SOURCE GeneReport for Unigene cluster: Hs.98381

SABiosciences Custom PCR Arrays for PRSS35

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRSS35 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRSS35

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRSS35

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for PRSS35 gene from 4/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Prss35^{1 , 5}	protease, serine, 35^{1, 5}	78.32(n)¹ 78(a)¹		9 (46.58 cM)⁵ 244954¹ NM_178738.3¹ NP_848853.2¹ 86743633⁵
chicken (Gallus gallus)	Aves	PRSS35¹	protease, serine, 35	70.39(n) 70.63(a)		421839 XM_419860.2 XP_419860.1
lizard (Anolis carolinensis)	Reptilia	PRSS35⁶	--	66(a)	1 ↔ 1	1(197521220-197522467)
zebrafish (Danio rerio)	Actinopterygii	prss35¹	protease, serine, 35	60.31(n) 56.92(a)		431759 NM_001002212.1 NP_001002212.1

ENSEMBL Gene Tree for PRSS35 (if available)
TreeFam Gene Tree for PRSS35 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for PRSS35 gene

PRSS23²

1 SIMAP similar gene for PRSS35 using alignment to 1 protein entry: PRS35_HUMAN:

PRSS23

PRSS35 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs185950890^1,2		--	84220220(+)	`CCTGGA/GAGGTG`	2	--	us2k¹		0	--	--	--	--
rs12204318^1,2	C,F,H,	--	84220405(+)	`AATACG/AAAGCA`	2	--	us2k¹		26		NS EA NA WA	2910
rs189793400^1,2		--	84220422(+)	`CCAGAC/TGAAGT`	2	--	us2k¹		0	--	--	--	--
rs9341960^1,2	C,F,A,H,	--	84220535(+)	`GGGCAT/GGAAAA`	2	--	us2k¹ tfbs³		17		NS EA NA WA	2340
rs116231485^1,2	C,F,	--	84220613(+)	`GACCTG/CGGTCC`	2	--	us2k¹		1		WA	118
rs78153469^1,2	F,	--	84220747(+)	`CACAGC/TTATTT`	2	--	us2k¹		1		WA	118
rs73751537^1,2	C,	--	84220763(+)	`CAGGCG/AGAATT`	2	--	us2k¹		2		WA	120
rs9341961^1,2	C,F,A,H,	--	84220770(+)	`AATTCC/TCATTC`	2	--	us2k¹ tfbs³		28		EA NA NS CSA WA	2972
rs150789977^1,2		--	84220802(+)	`GACTTC/TTCCAC`	2	--	us2k¹		0	--	--	--	--
rs181396853^1,2		--	84220812(+)	`CACTCA/CATCTG`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for PRSS35 (84222194 - 84235423 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PRSS35: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRSS35

DNA2.0 Custom Variant and Variant Library Synthesis for PRSS35

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

PRSS35 for disorders About MalaCards

PRSS35 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: PRSS35 (2 documents)

Export disorders for PRSS35 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for PRSS35 gene integrated from 9 sources:
(articles sorted by number of sources associating them with PRSS35)

Utopia: connect your pdf to the dynamic
world of online information

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
The identification of novel ovarian proteases through the use of genomic and bioinformatic methodologies. (PubMed id 16870946)^{1, 9} Miyakoshi K....Hennebold J.D. (2006)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Novel cleft susceptibility genes in chromosome 6q. (PubMed id 20511563)¹ Letra A....Vieira A.R. (2010)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)² Mungall A.J.... Beck S. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
A simple fold with variations: the pacifastin inhibit or family. (PubMed id 14990440)⁹ GA!spA!ri Z....Perczel A. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 167681	HGNC: 21387	AceView: PRSS35	Ensembl:ENSG00000146250	euGenes: HUgn167681
ECgene: PRSS35	H-InvDB: PRSS35

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for PRSS35	Pharmacogenomics, SNPs, Pathways

Intellectual Property for PRSS35 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for PRSS35 gene:
Search GeneIP for patents involving PRSS35

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


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	Browse OriGene Antibodies		OriGene shRNA RFP for PRSS35
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PRSS35		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRSS35
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PRSS35
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRSS35
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRSS35
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRSS35
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	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRSS35

	GenScript Custom Purified and Recombinant Proteins Services for PRSS35		GenScript cDNA clones with any tag delivered in your preferred vector for PRSS35
	GenScript Custom Assay Services for PRSS35		GenScript Custom Superior Antibodies Services for PRSS35
	GenScript Custom overexpressing Cell Line Services for PRSS35		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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ThermoFisher Antibody for PRSS35

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRSS35

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes PRSS35 gene at Home site.

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PRSS35 Gene

protease, serine, 35

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PRSS35 Gene

protease, serine, 35

Aliasesfor PRSS35 gene

Summariesfor PRSS35 gene

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Proteinsfor PRSS35 gene

Protein Domains /Familiesfor PRSS35 gene

Functionfor PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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for PRSS35 gene

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