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PRSS27 Gene

protein-coding   GIFtS: 46
GCID: GC16M002768

Protease, Serine 27

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Protease, Serine 271 2     EC 3.4.21.-3
MPN2 3     Marapsin3
CAPH22     Pancreasin3
Channel-Activating Protease 22     EC 3.4.218
marapsin2     EC 3.4.21.48
pancreasin2     EC 3.4.21.438
Serine Protease 272     

External Ids:    HGNC: 154751   Entrez Gene: 838862   Ensembl: ENSG000001723827   OMIM: 6080185   UniProtKB: Q9BQR33   

Export aliases for PRSS27 gene to outside databases

Previous GC identifers: GC16U990229 GC16M002704 GC16M002705 GC16M002733


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PRSS27 Gene:
Pancreasin is a pancreatic tryptic serine peptidase that cleaves peptides after an arginine residue.(supplied by
OMIM, Sep 2003)

GeneCards Summary for PRSS27 Gene:
PRSS27 (protease, serine 27) is a protein-coding gene. Diseases associated with PRSS27 include cholecystitis, and peptic ulcer. GO annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is PRSS46.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NT_010393.17  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PRSS27 gene promoter:
         CREB   deltaCREB   NRSF form 1   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRSS27 promoter sequence
   Search Chromatin IP Primers for PRSS27

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRSS27


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

PRSS27 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRSS27 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M002768:  view genomic region     (about GC identifiers)

Start:
2,762,419 bp from pter      End:
2,770,552 bp from pter
Size:
8,134 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PRS27_HUMAN, Q9BQR3 (See protein sequence)
Recommended Name: Serine protease 27 precursor  
Size: 290 amino acids; 31940 Da

Explore the universe of human proteins at neXtProt for PRSS27: NX_Q9BQR3

Explore proteomics data for PRSS27 at MOPED

Post-translational modifications: 

  • N-glycosylated1
  • Glycosylation2 at Asn55, Asn79
  • Selected DME Specific Peptides for PRSS27 (Q9BQR3) (see all 12)
     CWVTGWG  SGGPLVC  SWGEGCA  FCGGSLI 


    See PRSS27 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_114154.1  
    ENSEMBL proteins: 
     ENSP00000306390   ENSP00000455636   ENSP00000456886  

    PRSS27 Human Recombinant Protein Products:

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    Sino Biological Recombinant Protein for PRSS27
    Sino Biological Cell Lysate for PRSS27
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    PRSS27 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals PRSS27 Antibodies
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    LSBio Antibodies in human, mouse, rat for PRSS27

    PRSS27 Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PRSS: Serine peptidases / Serine peptidases

    4 InterPro protein domains:
     IPR001314 Peptidase_S1A
     IPR001254 Peptidase_S1
     IPR018114 Peptidase_S1_AS
     IPR009003 Trypsin-like_Pept_dom

    Graphical View of Domain Structure for InterPro Entry Q9BQR3

    ProtoNet protein and cluster: Q9BQR3

    2 Blocks protein domains:
    IPB001254 Serine protease
    IPB001314 Chymotrypsin serine protease family (S1) signature


    UniProtKB/Swiss-Prot: PRS27_HUMAN, Q9BQR3
    Similarity: Belongs to the peptidase S1 family
    Similarity: Contains 1 peptidase S1 domain


    PRSS27 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Numbers (IUBMB): EC 3.4.21.432 EC 3.4.21.42 EC 3.4.212 EC 3.4.21.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004252serine-type endopeptidase activity IEA--
         
    PRSS27 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for PRSS27:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Prss27):
     normal 

    PRSS27 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRSS27
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PRSS27

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRSS27
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRSS27

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate PRSS27:
    hsa-miR-4283
    SwitchGear 3'UTR luciferase reporter plasmidPRSS27 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat PRSS27

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    GenScript: all cDNA clones in your preferred vector: PRSS27 (NM_031948)
    Sino Biological Human cDNA Clone for PRSS27
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRSS27

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRSS27


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PRS27_HUMAN, Q9BQR3: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane2
    endoplasmic reticulum1
    lysosome1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005886plasma membrane IEA--

    PRSS27 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRSS27
    Interactions:

        Search GeneGlobe Interaction Network for PRSS27

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----

    PRSS27 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRSS27 (PRS27)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PRSS27 gene: 
    NM_031948.3  

    Unigene Cluster for PRSS27:

    Protease, serine 27
    Hs.332878  [show with all ESTs]
    Unigene Representative Sequence: AK126510
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000302641 ENST00000543965(uc002cre.3) ENST00000565903(uc002crf.3 uc002crg.3)
    ENST00000562249(uc010bst.1) ENST00000566492
    miRNA
    Products:
         
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    1 qRT-PCR Assays for microRNA that regulate PRSS27:
    hsa-miR-4283
    SwitchGear 3'UTR luciferase reporter plasmidPRSS27 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PRSS27
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    OriGene clones in human, mouse for PRSS27 (see all 5)
    OriGene ORF clones in mouse, rat for PRSS27
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRSS27 (NM_031948)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRSS27
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRSS27
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PRSS27
    OriGene qSTAR qPCR primer pairs in human, mouse for PRSS27
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PRSS27
      QuantiTect SYBR Green Assays in human, mouse, rat PRSS27
      QuantiFast Probe-based Assays in human, mouse, rat PRSS27

    Additional mRNA sequence: 

    AB056161.1 AJ306593.1 AK126510.1 AK310214.1 AY030095.1 AY359106.1 BC034294.2 BC036912.2 

    3 DOTS entries:

    DT.40223324  DT.95149810  DT.95203996 

    Selected AceView cDNA sequences (see all 30):

    AJ306593 AY359106 AI272325 BC034294 BM832898 BF353799 AK126510 NM_031948 
    AY030095 BC036912 BX284078 AB056161 BM670388 BG679626 BM792755 AA321681 
    BM712096 BM854083 AK055576 BI254797 BF909691 AW170323 BF916269 AW084167 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PRSS27 expression in normal human tissues (normalized intensities)      PRSS27 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    PRSS27 Expression
    About this image


    PRSS27 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Heart (Cardiovascular System)
             Atrioventricular Canal Cells Atrioventricular Canal
     
     Esophagus (Gastrointestinal Tract)
    PRSS27 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRSS27 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.332878

    UniProtKB/Swiss-Prot: PRS27_HUMAN, Q9BQR3
    Tissue specificity: Expressed predominantly in the pancreas

        Custom PCR Arrays for PRSS27
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRSS27

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PRSS27 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prss271 , 5 protease, serine, 271, 5 81.87(n)1
    78.83(a)1
      17 (12.21 cM)5
    2131711  NM_175440.41  NP_780649.11 
     240381445 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    48(a)
    48(a)
    many ↔ many
    many ↔ many
    GL343287.1(1650442-1668815)
    GL343287.1(1697243-1701085)
    African clawed frog
    (Xenopus laevis)
    Amphibia BX854139.12   -- 72.56(n)    BX854139.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000015201 serine protease 27-like 50.07(n)
    47.06(a)
      100001520  XM_001341462.2  XP_001341498.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0045691 AgaP_AGAP004569 46.46(n)
    39(a)
      4577070  XM_001237552.3  XP_001237553.3 


    ENSEMBL Gene Tree for PRSS27 (if available)
    TreeFam Gene Tree for PRSS27 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PRSS27 gene
    PRSS462  PRSS482  PRSS222  TMPRSS92  PRSS212  PRSS452  TPSG12  TPSD12  
    PRSS382  TPSAB12  PRSS532  PRSS502  PRSS422  PRSS362  PRSS332  PRSS82  
    TPSB22  
    Selected SIMAP similar genes for PRSS27 using alignment to 2 protein entries:     PRS27_HUMAN (see all proteins) (see all similar genes):
    PRSS22    PRSS21    TMPRSS9    serase-1B    KLKB1    PRSS44
    PRSS45    PRSS33    PRSS36    PRSS38    TPSB2    TPSAB1
    F9    F9 p22    ST14    TPSG1    factor IX F9    tryptaseC

    PRSS27 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PRSS27
    PGOHUM00000250633


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PRSS27 (see all 279)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs790494471,2
    C,F--2761925(+) TCAAGG/AGGAGA 1 -- ds50013Minor allele frequency- A:0.09CSA WA 122
    rs759453571,2
    C,F--2761932(+) GAGACG/TCCGGG 1 -- ds50013Minor allele frequency- T:0.09CSA WA 122
    rs727687511,2
    C,F--2761994(+) TGGGCA/GCCCAC 1 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1449454351,2
    --2762204(+) AAGGTA/GAGAGA 1 -- ds50010--------
    rs1154177781,2
    F--2762206(+) GGTGAG/AAGAAC 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1901689281,2
    --2762229(+) GGCAGC/GAGGTG 1 -- ds50010--------
    rs797322171,2
    C,F--2762269(+) CCCATA/GCTCTG 1 -- ds50013Minor allele frequency- G:0.13CSA WA 121
    rs1930633631,2
    --2762290(+) CGCCTC/TGGGCA 1 -- ds50010--------
    rs1145714001,2
    F--2762355(+) CCACCT/CGGGCT 1 -- ds50011Minor allele frequency- C:0.02WA 118
    rs1856870321,2
    --2762424(+) CAGCTC/GGCACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for PRSS27 (2762419 - 2770552 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PRSS27 (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422427CNV Duplication17116639
    dgv2545n71CNV Loss21882294
    dgv2572n71CNV Loss21882294
    nsv905165CNV Loss21882294
    nsv905152CNV Loss21882294
    nsv905158CNV Loss21882294
    nsv905139CNV Loss21882294
    nsv471073CNV Loss18288195
    nsv905164CNV Loss21882294
    nsv905161CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PRSS27
    DNA2.0 Custom Variant and Variant Library Synthesis for PRSS27

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608018    OMIM disorders: --

    7 diseases for PRSS27:    About MalaCards
    cholecystitis    peptic ulcer    pancreatitis    psoriasis
    tonsillitis    cerebritis    prostatitis


    PRSS27 for disorders           About GeneDecksing


    Export disorders for PRSS27 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PRSS27 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with PRSS27)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure and activity of human pancreasin, a novel tryptic serine peptidase expressed primarily by the pancreas. (PubMed id 12441343)1, 2, 9 Bhagwandin V.J....Caughey G.H. (J. Biol. Chem. 2003)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds. (PubMed id 18948266)1, 9 Li W....Kirchhofer D. (J. Biol. Chem. 2009)
    5. Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors. (PubMed id 23447538)1 Raman K....Caughey G.H. (J. Biol. Chem. 2013)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. (PubMed id )2 
    9. ENaC proteolytic regulation by channel-activating protease 2. (PubMed id 18852303)9 GarcA-a-Caballero A....Stutts M.J. (J. Gen. Physiol. 2008)
    10. Mast cell alpha and beta tryptases changed rapidly during primate speciation and evolved from gamma-like transmembrane peptidases in ancestral vertebrates. (PubMed id 17947681)9 Trivedi N.N....Caughey G.H. (J. Immunol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83886 HGNC: 15475 AceView: MPN Ensembl:ENSG00000172382 euGenes: HUgn83886
    ECgene: PRSS27 H-InvDB: PRSS27

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PRSS27 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PRSS27 gene:
    Search GeneIP for patents involving PRSS27

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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