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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PRSS22 Gene

protein-coding   GIFtS: 49
GCID: GC16M002902

protease, serine, 22

 Explore 3 diseases affiliated with
PRSS22 via our new
 Human Malady Compendium 
Biological research products
for PRSS22
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Protease, Serine, 221 2     Brain-Specific Serine Protease 42
BSSP-41 2 3     Prosemin1
HBSSP-41     Protease, Serine S1 Family Member 222
Serine Protease 222 3     BSSP43
Serine Protease 262 3     EC 3.4.21.-3
Tryptase Epsilon2 3     PRSS263
SP001LA1     EC 3.4.218

External Ids:    HGNC: 143681   Entrez Gene: 640632   Ensembl: ENSG000000050017   OMIM: 6093435   UniProtKB: Q9GZN43   

Export aliases for PRSS22 gene to outside databases

Previous GC identifers: GC16M002923 GC16M002903 GC16M002842 GC16M002869


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PRSS22:
This gene encodes a member of the trypsin family of serine proteases. The enzyme is expressed in the airways in a
developmentally regulated manner. The gene is part of a cluster of serine protease genes on chromosome 16. (provided
by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: BSSP4_HUMAN, Q9GZN4
Function: Preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA

Gene Wiki entry for PRSS22


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PRSS22 gene promoter:
         HEN1   STAT1   AP-1   FOXD3   Pax-2   MyoD   Cart-1   Pax-2a   ZIC2/Zic2   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRSS22 promoter sequence
   Search SABiosciences Chromatin IP Primers for PRSS22

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRSS22


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

PRSS22 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRSS22 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M002902:  view genomic region     (about GC identifiers)

Start:
2,902,728 bp from pter      End:
2,908,631 bp from pter
Size:
5,904 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: BSSP4_HUMAN, Q9GZN4 (See protein sequence)
Recommended Name: Brain-specific serine protease 4 precursor  
Size: 317 amino acids; 33732 Da
Subcellular location: Secreted
Sequence caution: Sequence=AAB93671.1; Type=Erroneous gene model prediction; Sequence=AAQ88762.1; Type=Erroneous
initiation;
Secondary accessions: O43342 Q6UXE0

Explore the universe of human proteins at neXtProt for PRSS22: NX_Q9GZN4

4 DME Specific Peptides for PRSS22 (Q9GZN4)
 DIALVRL  GDSGGPL  SWGEGCA  CWISGWG 

PRSS22 Protein expression data from MOPED and PaxDb:    About this image 
Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_071402.1  
ENSEMBL proteins: 
 ENSP00000161006   ENSP00000458506   ENSP00000458562  

Human Recombinant Protein Products: 
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R&D Systems Recombinant & Natural Proteins for PRSS22 (Tryptase epsilon/BSSP-4)
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OriGene Protein Over-expression Lysate: PRSS22
OriGene Custom Protein Services for PRSS22 
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Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for PRSS22

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region IEA--


PRSS22 for ontologies           About GeneDecksing



PRSS22 Antibody Products: 
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Uscn ELISAs and CLIAs for PRSS22


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

PRSS22 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR001314 Peptidase_S1A
 IPR001254 Peptidase_S1
 IPR018114 Peptidase_S1_AS
 IPR009003 Trypsin-like_Pept_dom

Graphical View of Domain Structure for InterPro Entry Q9GZN4

ProtoNet protein and cluster: Q9GZN4

2 Blocks protein families:
IPB001254 Serine protease
IPB001314 Chymotrypsin serine protease family (S1) signature


UniProtKB/Swiss-Prot: BSSP4_HUMAN, Q9GZN4
Similarity: Belongs to the peptidase S1 family
Similarity: Contains 1 peptidase S1 domain


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

     UniProtKB/Swiss-Prot: BSSP4_HUMAN, Q9GZN4
Function: Preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA

Enzyme Numbers (IUBMB): EC 3.4.212 EC 3.4.21.-1

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRSS22
8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate PRSS22 (see all 15):
hsa-miR-98 hsa-miR-520d-5p hsa-let-7d hsa-let-7c hsa-let-7i hsa-let-7g hsa-let-7e hsa-miR-3927
SwitchGear 3'UTR luciferase reporter plasmidPRSS22 3' UTR sequence
Inhib. RNA
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OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PRSS22 (see all 7)
OriGene shRNA RFP: PRSS22
OriGene siRNA: PRSS22
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRSS22

Gene Editing
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRSS22 

Cell Line
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Search LifeMap BioReagents cell lines for PRSS22

In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRSS22

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004252serine-type endopeptidase activity IEA--


PRSS22 for ontologies           About GeneDecksing


Animal Models:
     Mouse knock-out Prss22tm1Lex for PRSS22
     1 MGI phenotypic allele for Prss22 (no phenotypes)

PRSS22 for phenotypes           About GeneDecksing


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRSS22

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006508proteolysis IEA--


PRSS22 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for PRSS22
Search CenterWatch for drugs/clinical trials and news about PRSS22 / BSSP4 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for PRSS22 gene: 
NM_022119.3  

Unigene Cluster for PRSS22:

Protease, serine, 22
Hs.459709  [show with all ESTs]
Unigene Representative Sequence: BC009726
9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000161006(uc002cry.1) ENST00000571228 ENST00000575164 ENST00000576381
ENST00000572061 ENST00000574768 ENST00000577177 ENST00000570950 ENST00000573145


miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRSS22
8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate PRSS22 (see all 15):
hsa-miR-98 hsa-miR-520d-5p hsa-let-7d hsa-let-7c hsa-let-7i hsa-let-7g hsa-let-7e hsa-miR-3927
SwitchGear 3'UTR luciferase reporter plasmidPRSS22 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PRSS22 (see all 7)
OriGene shRNA RFP: PRSS22
OriGene siRNA: PRSS22
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRSS22
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRSS22
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: PRSS22 (NM_022119)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRSS22 
Primer
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OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRSS22
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PRSS22
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRSS22
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRSS22

Additional cDNA sequence: 

AB010779.1 AF321182.1 AK309624.1 AK310904.1 AY358396.1 BC009726.1 

6 DOTS entries:

DT.40126110  DT.95355311  DT.97839187  DT.100783115  DT.91934276  DT.99948582 

24/73 AceView cDNA sequences (see all 73):

BX356243 BX395818 BM845831 CR608374 CR626637 AF321182 AB010779 AI940071 
CA489887 AW583133 BM844455 BM818012 AI274014 BE907706 BX280281 NM_022119 
CR591551 CA488787 BG824600 BX334710 BX395817 BQ893064 BX334709 AY358396 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for PRSS22    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b
SP1:                          -                                             
SP2:                    -     -     -     -     -                           
SP3:                    -     -                                             
SP4:                                                                        
SP5:                                                                        


ECgene alternative splicing isoforms for PRSS22

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

PRSS22 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCCCGCCCC

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See PRSS22 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PRSS22

SOURCE GeneReport for Unigene cluster: Hs.459709

UniProtKB/Swiss-Prot: BSSP4_HUMAN, Q9GZN4
Tissue specificity: Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal
lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland

    SABiosciences Custom PCR Arrays for PRSS22
Primer
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Browse OriGene validated miRNA SYBR primer pairs
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QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRSS22
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRSS22
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRSS22

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for PRSS22 gene from 2/18 species (see all 18)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
lizard
(Anolis carolinensis)
Reptilia --
--
(see all 3)
--
48(a)
47(a)
(see all 3)
1 ↔ many
possible ortholog
(see all 3)
GL343287.1(1662229-1665762)
GL343287.1(1697243-1701085)
fruit fly
(Drosophila melanogaster)
Insecta Sb3
CG81721
cytoskeleton organization and biogenesis
serine-type more3
CG81721
37(a)
(best of 7)3
48.84(n)1
37.14(a)1
  3 89B93
359051  NM_001103765.21  NP_001097235.21 


ENSEMBL Gene Tree for PRSS22 (if available)
TreeFam Gene Tree for PRSS22 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for PRSS22 gene
PRSS462  PRSS552  PRSS482  PRSS272  PRSS212  PRSS452  TPSG12  TPSD12  
PRSS382  TPSAB12  PRSS532  PRSS502  PRSS422  PRSS362  PRSS332  KLKB12  
PRSS82  F112  OVCH12  
18/92 SIMAP similar genes for PRSS22 using alignment to 3 protein entries:     BSSP4_HUMAN (see all proteins) (see all similar genes):
PRSS27    serase-1B    TMPRSS9    F11    TMPRSS11B    TMPRSS11F
TMPRSS6    TPSG1    TPSAB1    TPSB2    KLKB1    tryptaseC
TMPRSS15    PRSS21    PRSS33    TMPRSS5    TMPRSS11A    DESC1

PRSS22 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/159 NCBI SNPs in PRSS22 are shown (see all 159    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 16 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1911573781,2
--2902302(+) CTGAGG/TCCCCT 1 -- ds50010--------
rs1499524981,2
--2902333(+) CAGAAC/GGGGGG 1 -- ds50010--------
rs71863261,2
C,F,A,H,--2902431(+) TTCGGG/AGTCCC 1 -- ds500121Minor allele frequency- A:0.47NS EA NA WA CSA 2335
rs1137338901,2
--2902439(+) CCCAAT/CCCCTC 1 -- ds50011Minor allele frequency- C:0.00CSA 1
rs124483851,2
H--2902449(+) CTCCTA/CCCCTT 1 -- ds50010--------
rs1153399501,2
F,--2902510(+) CCATCG/AGCTGC 1 -- ds50011Minor allele frequency- A:0.03WA 118
rs1420397681,2
--2902654(+) TAGGCC/TAACAT 1 -- ds50010--------
rs127861,2
C,F,A,H,--2902832(-) CCCCAG/CCGCTT 1 -- ut31 ese310Minor allele frequency- C:0.20MN NS EA NA CSA WA 1025
rs1456315271,2
C,--2902840(+) GGCCC-/GGGGGC 1 -- ut310--------
rs573928671,2
C--2902841(+) GGGGCG/-GGGGC 1 -- ut311Minor allele frequency- -:0.00NA 2

HapMap Linkage Disequilibrium report for PRSS22 (2902728 - 2908631 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for PRSS22
     6 CNVs: 35373 35377 35378 35375 35376 35374

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRSS22
DNA2.0 Custom Variant and Variant Library Synthesis for PRSS22

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

PRSS22 for disorders           About GeneDecksing

OMIM gene information: 609343    OMIM disorders: --

3 diseases for PRSS22:    About MalaCards
psoriasis    thyroiditis    prostatitis


Export disorders for PRSS22 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for PRSS22 gene integrated from 9 sources:
(articles sorted by number of sources associating them with PRSS22)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Human tryptase epsilon (PRSS22), a new member of the chromosome 16p13.3 family of human serine proteases expressed in airway epithelial cells. (PubMed id 11602603)1, 2, 3, 9 Wong G.W.... Stevens R.L. (2001)
  2. Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22. (PubMed id 15701722)1, 3, 9 Yasuda S....Stevens R.L. (2005)
  3. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
  6. A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells. (PubMed id 16176265)1, 9 Mitsui S....Yamaguchi N. (2005)
  7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  9. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
  10. The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds. (PubMed id 18948266)9 Li W....Kirchhofer D. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 64063 HGNC: 14368 AceView: PRSS22 Ensembl:ENSG00000005001 euGenes: HUgn64063
ECgene: PRSS22 H-InvDB: PRSS22

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for PRSS22 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for PRSS22 gene:
Search GeneIP for patents involving PRSS22

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PRSS22
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 Regulatory tfbs in PRSS22 promoter
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 Search for Antibodies for PRSS22 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for PRSS22
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 PRSS22 Proteins, Antibodies, CLIAs, and ELISAs
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 SwitchGear Promoter luciferase reporter plasmids for PRSS22
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 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRSS22
       
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