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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PRSS2 Gene

protein-coding   GIFtS: 57
GCID: GC07Pg41870

protease, serine, 2 (trypsin 2)
 Explore 38 diseases affiliated with
PRSS2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for PRSS2    

Aliases
for PRSS2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Protease, Serine, 2 (Trypsin 2)1 2     TRY82
TRY21 2 3 5     Protease Serine 2 Preproprotein2
Anionic Trypsinogen2 3     Protease, Serine, 2, Preproprotein2
Serine Protease 22 3     Trypsin 22
Trypsin II2 3     Trypsin-21
TRYP22 3     Trypsinogen 22
EC 3.4.21.43 8     EC 3.4.218

External Ids:    HGNC: 94831   Entrez Gene: 56452   OMIM: 6015645   UniProtKB: P074783   

Export aliases for PRSS2 gene to outside databases

Previous GC identifers: GC07P140772 GC07P140731 GC07P141821 GC07P141899 GC07P141902 GC07P141676 GC07P141990 GC07P142167 GC07P142178 GC07P142457 GC07P142298


Summaries
for PRSS2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for PRSS2:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted
by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the
carboxyl group of lysine or arginine. This gene and several other trypsinogen genes are localized to the T cell
receptor beta locus on chromosome 7. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TRY2_HUMAN, P07478
Function: In the ileum, may be involved in defensin processing, including DEFA5




Genomic Views
for PRSS2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:NT_079596.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for PRSS2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): PRSS2 promoter sequence
   Search SABiosciences Chromatin IP Primers for PRSS2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRSS2


Genomic Location:
Chromosome:7   

Entrez Gene cytogenetic band: 7q34   HGNC cytogenetic band: 7q34

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07Pg41870:  view genomic region     (about GC identifiers)

Start:
 141,870,508 bp from start of contig CRA_TCAGchr7v2      End:
 141,874,093 bp from start of contig CRA_TCAGchr7v2
Size:
 3,586 bases      Orientation:
 plus strand

Proteins
for PRSS2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TRY2_HUMAN, P07478 (See protein sequence)
Recommended Name: Trypsin-2 precursor  
Size: 247 amino acids; 26488 Da
Cofactor: Binds 1 calcium ion per subunit (By similarity)
Subcellular location: Secreted, extracellular space

Explore the universe of human proteins at neXtProt for PRSS2: NX_P07478

Post-translational modifications:

  • Sulfated on tyrosine1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P07478

    • 4/20 DME Specific Peptides for PRSS2 (P07478) (see all 20)
     EGGKDSC  PGVYTKV  QGIVSWG  CEASYPG 

    PRSS2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002761.1  Reactome Protein details: P07478
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for PRSS2 (Trypsin 2/PRSS2)
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    Novus Biologicals PRSS2 Protein
    Novus Biologicals PRSS2 Lysates
    Sino Biological Recombinant Protein for PRSS2
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PRSS2

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IMP16192646
    GO:0031012extracellular matrix TAS12731883


    PRSS2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for PRSS2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PRSS2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001314 Peptidase_S1A
     IPR001254 Peptidase_S1
     IPR018114 Peptidase_S1_AS
     IPR009003 Trypsin-like_Pept_dom

    Graphical View of Domain Structure for InterPro Entry P07478

    ProtoNet protein and cluster: P07478

    2 Blocks protein families:
    IPB001254 Serine protease
    IPB001314 Chymotrypsin serine protease family (S1) signature


    UniProtKB/Swiss-Prot: TRY2_HUMAN, P07478
    Similarity: Belongs to the peptidase S1 family
    Similarity: Contains 1 peptidase S1 domain


    Function
    for PRSS2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TRY2_HUMAN, P07478
    Function: In the ileum, may be involved in defensin processing, including DEFA5
    Catalytic activity: Preferential cleavage: Arg- -Xaa, Lys- -Xaa

         Genatlas biochemistry entry for PRSS2:
    protease serine 2,trypsin 2,expressed in pancreas

    Enzyme Numbers (IUBMB): EC 3.4.21.41 2 EC 3.4.212

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: PRSS2
    OriGene siRNA: PRSS2
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    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for PRSS2

    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for PRSS2

    In Situ Assay
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         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for PRSS2

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004252serine-type endopeptidase activity IDA12709065
    GO:0005509calcium ion binding IDA12709065
    GO:0005515protein binding IPI16192646


    PRSS2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for PRSS2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Degradation of the extracellular matrix
    		Degradation of the extracellular matrix1.00
    		Activation of Matrix Metalloproteinases0.40
    		Degradation of collagen0.79
    2Immune System
    		Immune System1.00
    		Innate Immune System0.46
    3Alpha-defensins
    		Alpha-defensins1.00
    4Protein digestion and absorption
    		Protein digestion and absorption1.00
    5Pancreatic secretion
    		Pancreatic secretion1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/8        Reactome Pathways for PRSS2 (see all 8)
        Alpha-defensins
    Degradation of collagen
    Activation of Matrix Metalloproteinases
    Extracellular matrix organization
    Defensins


    4         Kegg Pathways  (Kegg details for PRSS2):
        Neuroactive ligand-receptor interaction
    Pancreatic secretion
    Protein digestion and absorption
    Influenza A


    PRSS2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PRSS2

    5 Interacting proteins for PRSS2 (P074783) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APPP050673I2D: score=1 
    BPIP172133I2D: score=1 
    MMP9P147803I2D: score=1 
    SERPINA1P010093I2D: score=1 
    SLPIP039733I2D: score=1 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis IDA12731883
    GO:0007586digestion IEA--
    GO:0022617extracellular matrix disassembly TAS--
    GO:0030198extracellular matrix organization TAS--
    GO:0030307positive regulation of cell growth TAS12731883


    PRSS2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for PRSS2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PRSS2 for compounds           About GeneDecksing

    EMD Millipore small molecules for PRSS2:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PRSS2

    1 HMDB Compound for PRSS2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    7 DrugBank Compounds for PRSS2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    2-Phenylethylamine-- 64-04-0target--17139284 17016423 10592235
    3-Phenylpropylamine-- --target--17139284 17016423 10592235
    Benzamidine-- 618-39-3target--17139284 17016423 10592235
    Benzylamine-- 100-46-9target--17139284 17016423 10592235
    Monoisopropylphosphorylserine-- --target--17139284 17016423 10592235
    O-Benzylsulfonyl-Serine-- --target--17139284 17016423 10592235
    Phosphorylisopropane-- --target--17139284 17016423 10592235

    3 Novoseek chemical compound relationships for PRSS2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    trypsinogen 79.6 12 11391623 (4), 14695529 (2), 18986305 (1), 15901841 (1) (see all 5)
    serine 65.7 24 12396005 (1), 12731883 (1), 14568388 (1), 19887787 (1) (see all 20)
    cysteine 0 1 16783151 (1)

    Search CenterWatch for drugs/clinical trials and news about PRSS2 / TRY2 

    Transcripts
    for PRSS2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PRSS2 gene: 
    NM_002770.2  

    Unigene Clusters for PRSS2:

    Protease, serine, 2 (trypsin 2)
    Hs.726742  [show with all ESTs], Hs.728780  [show with all ESTs]
    Unigene Representative Sequences: BM805032, BE970192

    miRNA
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRSS2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRSS2

    Additional cDNA sequence: 

    AY052784.1 BC103997.2 BC107784.1 DQ846872.1 DQ846873.1 NR_001296.3 

    24/39 DOTS entries (see all 39):

    DT.100043423  DT.121076322  DT.87078490  DT.121076949  DT.121075973  DT.91767689  DT.100828689  DT.100828691 
    DT.100045920  DT.91721728  DT.100828698  DT.121076237  DT.121076760  DT.97857442  DT.100045917  DT.121076636 
    DT.95235519  DT.121076424  DT.121075905  DT.95096077  DT.95259214  DT.102841077  DT.101976063  DT.100798707 

    5 AceView cDNA sequences:

    BC005814 NM_002770 BC030260 M27602 AY052784 

    GeneLoc Exon Structure


    Expression
    for PRSS2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PRSS2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCTGTGTGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    PRSS2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    PancreasIslets of LangerhansMature Beta CellsPancreas
    AdiposeBody Subcutaneous White AdiposeAdipose
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Posterior foregut-like cells (A scalable, suspensi...)

    See PRSS2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PRSS2

    SOURCE GeneReport for Unigene clusters: Hs.726742 Hs.728780

    UniProtKB/Swiss-Prot: TRY2_HUMAN, P07478
    Tissue specificity: Expressed in Paneth cells, at the base of small intestinal crypts

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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for PRSS2

    Orthologs
    for PRSS2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for PRSS2 gene from 3 species (see representative species )    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Prss25 protease, serine, 2   --   6 (19.67 cM) 41521787 
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.82612 Transcribed sequence with weak similarity to protein more 79(n)    CF225765.1 
    rainbow trout
    (Oncorhynchus mykiss)    		 Actinopterygii Omy.86542 Oncorhynchus mykiss transcribed sequence with weak more 78.78(n)    BX076451.1 

    Paralogs
    for PRSS2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for PRSS2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1 NCBI SNPs in PRSS2 are shown     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs617346591,2
    		C,Fother136810371(+) TCGAGA/GGAGGC 2 R G mis10--------

    HapMap Linkage Disequilibrium report for PRSS2 (141870508 - 141874093 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 10 variations for PRSS2
         10 CNVs: 94908 82208 30269 10215 38135 94907 4566 4567 53795 9071
    Human Gene Mutation Database (HGMD): PRSS2

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for PRSS2

    Disorders / Diseases
    for PRSS2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PRSS2 for disorders           About GeneDecksing

    OMIM gene information: 601564    OMIM disorders: --

    20/38 diseases for PRSS2 (see all 38):    About MalaCards
    pancreatitis, chronic, protection against    linitis plastica    tropical calcific pancreatitis    pemphigus foliaceus
    hereditary angioedema    malignant ovarian cyst    ovarian cyst    angioedema
    bronchopulmonary dysplasia    pemphigus    rheumatoid arthritis    pancreatitis
    acute pancreatitis    cystic fibrosis    sjogren's syndrome    hereditary pancreatitis
    keratoconus    synovitis    insulinoma    colorectal cancer

    10 Novoseek disease relationships for PRSS2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pancreatitis 38.1 3 14695529 (2), 19077465 (1)
    acute pancreatitis 26.9 2 8760740 (2)
    respiratory distress syndrome 16.9 3 12949286 (2), 15879299 (1)
    colorectal cancer 14.3 2 11391623 (1), 17850591 (1)
    lung diseases 13.3 2 11585105 (1), 15879299 (1)
    metastasis 10.5 1 9261109 (1)
    tumors 4.92 8 11391623 (2), 9261109 (1), 18221368 (1), 17855650 (1)
    inflammation 0 1 15879299 (1)
    rheumatoid arthritis 0 3 16192646 (3)
    cancer 0 1 18062964 (1)

    Human Genome Epidemiology (HuGE) Navigator: PRSS2 (8 documents)

    Export disorders for PRSS2 gene to outside databases

    Publications
    for PRSS2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PRSS2 gene, integrated from 9 sources (see all 110):
    (articles sorted by number of sources associating them with PRSS2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens. (PubMed id 3011602)1, 2, 3 Emi M....Matsubara K. (1986)
    2. Immunoreactive anionic and cationic trypsin in human serum. (PubMed id 2598466)1, 2 Kimland M.... Borgstroem A. (1989)
    3. Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma. (PubMed id 18062964)1, 9 Vilen S.T....Salo T. (2008)
    4. Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue. (PubMed id 16192646)1, 9 Stenman M....Konttinen Y.T. (2005)
    5. Activation of type IV procollagenases by human tumor-associated trypsin-2. (PubMed id 9261109)1, 9 Sorsa T....Stenman U.H. (1997)
    6. Human trypsinogen in colorectal cancer. (PubMed id 11391623)1, 9 Williams S.J....Antalis T.M. (2001)
    7. Tumor-associated trypsinogen-2 (trypsinogen-2) activates procollagenases (MMP-1, -8, -13) and stromelysin-1 (MMP-3) and degrades type I collagen. (PubMed id 12731883)1, 9 Moilanen M....Salo T. (2003)
    8. Matrix metalloproteinase (MMP)-9 type IV collagenase/gelatinase implicated in the pathogenesis of Sjogren's syndrome. (PubMed id 9822200)1, 9 Konttinen Y.T....Eisen A.Z. (1998)
    9. Identification of pancreatic juice proteins as biomar kers of pancreatic cancer. (PubMed id 20428826)1, 9 Gao J....Ma L. (2010)
    10. Divergent Roles of SPINK1 and PRSS2 Variants in Tropical Calcific Pancreatitis. (PubMed id 19077465)1, 9 Sundaresan S....Drenth J.P. (2008)

    External Searches for PRSS2 gene

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    Genome Databases showing PRSS2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5645 HGNC: 9483 AceView: PRSS2 euGenes: HUgn5645 ECgene: PRSS2 Kegg: 5645
    H-InvDB: PRSS2

    Other Databases showing PRSS2 gene

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    Specialized Databases showing PRSS2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for PRSS2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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