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PRRX2 Gene

protein-coding   GIFtS: 50
GCID: GC09P132427

Paired Related Homeobox 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Paired Related Homeobox 21 2     PRX-22 3
PRX22 3 5     Paired Mesoderm Homeobox Protein 22
Paired-Related Homeobox Protein 22 3     Paired-Like Homeodomain Protein PRX22
PMX22 3     

External Ids:    HGNC: 213381   Entrez Gene: 514502   Ensembl: ENSG000001671577   OMIM: 6046755   UniProtKB: Q998113   

Export aliases for PRRX2 gene to outside databases

Previous GC identifers: GC09P127803 GC09P129507 GC09P131467 GC09P102027


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PRRX2 Gene:
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression
is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in
adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role
in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The
expression patterns provide evidence consistent with a role in fetal skin development and a possible role in
cellular proliferation. (provided by RefSeq, Jul 2008)

GeneCards Summary for PRRX2 Gene:
PRRX2 (paired related homeobox 2) is a protein-coding gene. Diseases associated with PRRX2 include acute myeloid leukemia, and myeloid leukemia. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ALX1.

UniProtKB/Swiss-Prot: PRRX2_HUMAN, Q99811
Function: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of
development

Gene Wiki entry for PRRX2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PRRX2 gene promoter:
         HOXA9B   SRF   AML1a   SRF (504 AA)   FOXD3   Meis-1   Meis-1b   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for PRRX2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRRX2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.1   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.11

PRRX2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRRX2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P132427:  view genomic region     (about GC identifiers)

Start:
132,427,920 bp from pter      End:
132,484,953 bp from pter
Size:
57,034 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: PRRX2_HUMAN, Q99811 (See protein sequence)
Recommended Name: Paired mesoderm homeobox protein 2  
Size: 253 amino acids; 27079 Da
Developmental stage: Higher expression in fetus than in adult
Secondary accessions: Q5SZB5 Q9UIB3

Explore the universe of human proteins at neXtProt for PRRX2: NX_Q99811

Explore proteomics data for PRRX2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PRRX2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057391.1  
    ENSEMBL proteins: 
     ENSP00000361547  

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    Cloud-Clone Corp. CLIAs for PRRX2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PRD: Homeoboxes / PRD class

    4 InterPro protein domains:
     IPR003654 OAR_dom
     IPR017970 Homeobox_CS
     IPR001356 Homeobox_dom
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q99811

    ProtoNet protein and cluster: Q99811

    2 Blocks protein domains:
    IPB000047 Lambda and other repressor helix-turn-helix signature
    IPB003654 Paired-like homeodomain protein


    UniProtKB/Swiss-Prot: PRRX2_HUMAN, Q99811
    Similarity: Belongs to the paired homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    PRRX2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PRRX2_HUMAN, Q99811
    Function: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of
    development

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity NAS11063257
    GO:0043565sequence-specific DNA binding IEA--
         
    PRRX2 for ontologies           About GeneDecksing


    Phenotypes:
         15 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Prrx2):
     behavior/neurological  cardiovascular system  craniofacial  digestive/alimentary  embryogenesis 
     growth/size/body  hearing/vestibular/ear  homeostasis/metabolism  limbs/digits/tail  mortality/aging 
     nervous system  normal  respiratory system  skeleton  vision/eye 

    PRRX2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Prrx2tm1Mjk for PRRX2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRRX2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRRX2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRRX2

    miRNA
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    miRTarBase miRNAs that target PRRX2:
    hsa-mir-124-3p (MIRT023165)

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    3 qRT-PCR Assays for microRNAs that regulate PRRX2:
    hsa-miR-374c hsa-miR-655 hsa-miR-548u
    SwitchGear 3'UTR luciferase reporter plasmidPRRX2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PRRX2

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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRRX2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PRRX2_HUMAN, Q99811: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000228nuclear chromosome ----
    GO:0005634nucleus IEA--

    PRRX2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRRX2
    Interactions:

        Search GeneGlobe Interaction Network for PRRX2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for PRRX2 (Q998113 ENSP000003615474) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SOX10P566933, ENSP000003541304I2D: score=1 STRING: ENSP00000354130
    IFI16ENSP000003571134STRING: ENSP00000357113
    MNDAENSP000003571234STRING: ENSP00000357123
    CHEK2ENSP000003720234STRING: ENSP00000372023
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002053positive regulation of mesenchymal cell proliferation IEA--
    GO:0006355regulation of transcription, DNA-templated NAS9665387
    GO:0030326embryonic limb morphogenesis IEA--
    GO:0042472inner ear morphogenesis IEA--
    GO:0042474middle ear morphogenesis IEA--

    PRRX2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRRX2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PRRX2 gene: 
    NM_016307.3  

    Unigene Cluster for PRRX2:

    Paired related homeobox 2
    Hs.660115  [show with all ESTs]
    Unigene Representative Sequence: BM909706
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000372469(uc004byh.3)
    miRNA
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    hsa-miR-374c hsa-miR-655 hsa-miR-548u
    SwitchGear 3'UTR luciferase reporter plasmidPRRX2 3' UTR sequence
    Inhib. RNA
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat PRRX2
      QuantiFast Probe-based Assays in human, mouse, rat PRRX2

    Additional mRNA sequence: 

    AF061970.1 BC014645.1 U81600.1 

    2 DOTS entries:

    DT.203595  DT.121156198 

    Selected AceView cDNA sequences (see all 43):

    BM694729 AI917607 BX097188 NM_016307 AI821507 BC014645 AI923085 BF939198 
    AI420043 AA548667 AI674514 BE645185 BU731241 BM716252 AI203915 AI751739 
    AI808278 AW167940 AI697307 BM800161 U81600 BG055248 BU624928 AI936570 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PRRX2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCAACAGCA
    PRRX2 Expression
    About this image


    PRRX2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 17) fully expand
     
     Fibroblasts (Uncategorized)    fully expand to see all 10 entries
             Human Dermal Fibroblasts-adult (HDF-a)   
     
     Dermis (Integumentary System)    fully expand to see all 5 entries
             Human Dermal Fibroblasts-adult (HDF-a)   
     
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             Mandibular Process
             HyStem+BMP4-induced SK11 cells
     
     Head Mesenchyme (Muscoskeletal System)    fully expand to see all 4 entries
             Dental Mesenchymal Cells Branchial Arch 1
             Branchial Arch 1
     
     Cartilage (Muscoskeletal System)    fully expand to see all 3 entries
             HyStem+BMP4-induced E15 cells
    PRRX2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRRX2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.660115

    UniProtKB/Swiss-Prot: PRRX2_HUMAN, Q99811
    Tissue specificity: In fetal skin, highest expression found in cells of mesodermal origin within the dermal
    papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within
    the basal layers of the epidermis. Not expressed in dermis

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PRRX2 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prrx21 , 5 paired related homeobox 21, 5 85.09(n)1
    92.28(a)1
      2 (21.74 cM)5
    202041  NM_009116.21  NP_033142.21 
     308349725 
    chicken
    (Gallus gallus)
    Aves PRRX21 paired related homeobox 2 78.44(n)
    86.24(a)
      396314  XM_415476.4  XP_415476.3 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia prrx21 paired related homeobox 2 67.28(n)
    67.43(a)
      100488907  XM_002940757.2  XP_002940803.1 
    zebrafish
    (Danio rerio)
    Actinopterygii phox2ba6
    paired-like homeobox 2ba
    36(a)
    many ↔ many
    1(17816221-17821852) ENSDARG00000075330
    fruit fly
    (Drosophila melanogaster)
    Insecta CG98766
    --
    29(a)
    1 → many
    2R(18977626-18981785)


    ENSEMBL Gene Tree for PRRX2 (if available)
    TreeFam Gene Tree for PRRX2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PRRX2 gene
    ALX12  PHOX2B2  ARX2  RAX2  DRGX2  SHOX22  PRRX12  PHOX2A2  
    ALX42  ISX2  RAX22  ALX32  SHOX2  OTP2  
    10 SIMAP similar genes for PRRX2 using alignment to 1 protein entry:     PRRX2_HUMAN:
    PRRX1    PHOX2A    SHOX2    POU6F1    PHOX2B    RAX
    RAX2    PAX6    ARX    OTP

    PRRX2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PRRX2 (see all 1323)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1399179221,2
    C--132425940(+) GTAGTA/GGCCCT 1 -- us2k10--------
    rs78647171,2
    C,F--132426059(+) ACTGGC/TGCCTC 1 -- us2k11Minor allele frequency- T:0.16WA 118
    rs1494099041,2
    --132426160(+) CACCTA/GCACGG 1 -- us2k10--------
    rs107397561,2
    C,A,H--132426231(+) TATTTT/AATTTA 1 -- us2k19Minor allele frequency- A:0.27NA WA CSA EA 371
    rs1817809151,2
    --132426242(+) ATTTAC/TATATA 1 -- us2k10--------
    rs1861638191,2
    --132426256(+) TTTGAA/GATGGA 1 -- us2k10--------
    rs1909306491,2
    --132426327(+) CGCCTC/TCCAGG 1 -- us2k10--------
    rs1474973391,2
    --132426382(+) CAGGCA/GCCTGC 1 -- us2k10--------
    rs1478543051,2
    --132426411(+) TTTTTA/TATTAT 1 -- us2k10--------
    rs132912281,2
    C,F--132426773(+) GGCCAA/GCATGG 1 -- us2k17Minor allele frequency- G:0.16NA WA CSA EA 131
    rs1404122941,2
    C--132426916(+) ATCACA/GACACT 1 -- us2k10--------
    rs1851418151,2
    --132426966(+) AAAAAA/CTAAAA 1 -- us2k10--------
    rs1909848361,2
    --132427070(+) GATGTA/GCTGAA 1 -- us2k10--------
    rs1827439801,2
    --132427075(+) GCTGAA/CGGCTT 1 -- us2k10--------
    rs283709731,2
    C,F--132427226(+) CGCACA/GTCTTT 1 -- us2k15Minor allele frequency- G:0.16WA CSA NA EA 362
    rs1881759941,2
    --132427248(+) ATTGAA/CAAACA 1 -- us2k10--------
    rs285621841,2
    C,F,H--132427301(+) CCTGTC/TACCCG 1 -- us2k110Minor allele frequency- T:0.13NS NA WA CSA 1016
    rs745238611,2
    C,F--132427342(+) CAGGAA/GTTCTG 1 -- us2k11Minor allele frequency- G:0.02NA 120
    rs1162038491,2
    F--132427411(+) GGGGGT/AGGGCA 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1927719601,2
    --132427498(+) CAGGAA/GCCTGA 1 -- us2k10--------
    rs1169254981,2
    C,F--132427698(+) GGGGGG/AAATCC 1 -- us2k11Minor allele frequency- A:0.03EA 120
    rs104417591,2
    --132427804(+) ACACCC/GCTTCC 1 -- us2k1 trp30--------
    rs1151473011,2
    C,F--132427996(+) CCCGAC/AGTCAG 1 -- ut511Minor allele frequency- A:0.05WA 118
    rs736701521,2
    C,F--132428873(+) GTTTGC/TCCCGG 1 -- int14Minor allele frequency- T:0.20WA NA 242
    rs1874461741,2
    --132428900(+) GGAACA/GGCCCA 1 -- int10--------
    rs109884671,2
    C,F,A,H--132428927(+) CCGGCG/AGAGGT 1 -- int120Minor allele frequency- A:0.38NS EA WA NA CSA 2341
    rs795756001,2
    --132429006(+) CAGGAC/TGGCAG 1 -- int10--------
    rs1117977671,2
    C,F--132429055(+) AAGATG/AGAGAA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1923406891,2
    --132429111(+) ACCGGA/GGTCCT 1 -- int10--------
    rs736367431,2
    C,F--132429121(+) TCGCGG/ACTCAG 1 -- int12Minor allele frequency- A:0.04WA 120
    rs613561071,2
    C,F--132429148(+) GGGCCC/GGGTGA 1 -- int16Minor allele frequency- G:0.23NA CSA WA EA 363
    rs1846744761,2
    --132429368(+) GGTGGA/CTGCAG 1 -- int10--------
    rs1895110231,2
    --132429410(+) CGCCTA/GCGACA 1 -- int10--------
    rs70472201,2
    C,H--132429439(+) CACCTG/TCTGCC 1 -- int14Minor allele frequency- T:0.00NS EA 414
    rs600873801,2
    C--132429442(+) TTCTGAGTGCACCC
    AGCTGCTG
    /-
    CCAGC
    1 -- int11Minor allele frequency- -:0.00NA 2
    rs1427298311,2
    --132429537(+) TCCGGC/GGTGAG 1 -- int10--------
    rs1510149571,2
    --132429572(+) AGTTGG/TGGTTT 1 -- int10--------
    rs1926465571,2
    --132429687(+) TGAGGA/TCCTCA 1 -- int10--------
    rs780963871,2
    C,F--132429701(+) GCTCTG/AAGCCG 1 -- int12Minor allele frequency- A:0.12NA EA 240
    rs1408668261,2
    --132429765(+) ACTCCA/GGGGGT 1 -- int10--------
    rs1173260781,2
    C,F--132429795(+) AACTTG/AAAGGT 1 -- int11Minor allele frequency- A:0.03NA 120
    rs1422516031,2
    --132429835(+) GAAAG-/GAGAGAG 1 -- int10--------
    rs736701531,2
    C,F--132429839(+) GGAGAG/AAGAGA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs796366451,2
    C,F--132429889(+) AGAGGG/AGTGAG 1 -- int13Minor allele frequency- A:0.03CSA NA EA 242
    rs736701541,2
    C,F--132430008(+) TCTCCC/TGGACA 1 -- int12Minor allele frequency- T:0.15WA 120
    rs1156319351,2
    C,F--132430015(+) GACACG/AGTGTT 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1897172811,2
    --132430086(+) GTGGGC/TGCCTA 1 -- int10--------
    rs70320801,2
    C,F,A,H--132430178(+) GAGAGC/TCCATG 1 -- int122Minor allele frequency- T:0.46NS EA NA WA CSA 2045
    rs1170619401,2
    C,F--132430302(+) GAGGCG/ACTCGT 1 -- int11Minor allele frequency- A:0.04EA 120
    rs796863471,2
    C,F--132430350(+) GAGGAC/TGATGG 1 -- int11Minor allele frequency- T:0.03NA 120
    rs1813585421,2
    --132430362(+) GCCCTA/GGCAGG 1 -- int10--------
    rs767299411,2
    C,F--132430366(+) TGGCAG/AGGAGA 1 -- int12Minor allele frequency- A:0.12NA EA 240
    rs1447777361,2
    --132430404(+) CCGGAC/TCTGGG 1 -- int10--------
    rs1467129901,2
    C--132430559(+) TCTTTA/CCCCAT 1 -- int10--------
    rs1859166491,2
    --132430577(+) CCTTTC/GAAAGT 1 -- int10--------
    rs1406315901,2
    --132430723(+) GAGGTA/GGGTTT 1 -- int10--------
    rs1456885331,2
    --132430785(+) GGGGCA/GGTGGC 1 -- int10--------
    rs714994721,2
    C--132430938(+) GTAATC/TTCAGC 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1891020481,2
    C--132430966(+) CAGGAA/GAATCC 1 -- int10--------
    rs1382429121,2
    C--132431237(+) CCTGGC/GCAAGA 1 -- int10--------
    rs1495583791,2
    --132431259(+) CATCTC/TTACTA 1 -- int10--------
    rs123435851,2
    C,F--132431298(+) acagaC/Tgccta 1 -- int14Minor allele frequency- T:0.12NA EA 244
    rs1435732521,2
    C--132431343(+) AAAAA-/AAAG  
            
    AAAGA
    1 -- int10--------
    rs2011475781,2
    C--132431445(+) TTTTTA/TATTTA 1 -- int10--------
    rs3763685101,2
    C--132431446(+) TTTTAA/TTTTAA 1 -- int10--------
    rs1173412701,2
    C,F--132431537(+) ATGGCC/TGGGAA 1 -- int11Minor allele frequency- T:0.02NA 120
    rs1817224771,2
    --132431555(+) GCTTCA/GCCAGT 1 -- int10--------
    rs567661371,2
    C--132431609(+) AAACGC/ATGAGG 1 -- int15Minor allele frequency- A:0.12NA WA EA 362
    rs123437881,2
    C,F,H--132431625(+) ACCAGA/GCACGT 1 -- int115Minor allele frequency- N:0.00NS EA NA WA 998
    rs570568921,2
    C,F--132431629(+) GGCACG/ATTAGG 1 -- int11Minor allele frequency- A:0.05EA 120
    rs1432200211,2
    C--132431632(+) ACGTTA/GGGAAA 1 -- int10--------
    rs78669851,2
    C,F,A,H--132431637(+) AGGAAA/GACAAA 1 -- int115Minor allele frequency- G:0.11NA NS EA 1164
    rs123437951,2
    C,F,H--132431770(+) ATAAAC/AAAAGC 1 -- int16Minor allele frequency- A:0.07NS EA WA 540
    rs78672801,2
    C,F,A,H--132431784(+) TAGAGC/GCAGGC 1 -- int115Minor allele frequency- G:0.26NS EA NA WA 1028
    rs78672971,2
    C,F,H--132431826(+) GCGGCC/TAGTGC 1 -- int17Minor allele frequency- T:0.01NS EA NA WA 532
    rs169313861,2
    C,F--132431938(+) CTTGCA/GTCTAA 1 -- int14Minor allele frequency- G:0.02NA 262
    rs123438411,2
    C,F,H--132431948(+) AGGCAC/TGGGGC 1 -- int18Minor allele frequency- T:0.09NS EA NA WA 780
    rs126845551,2
    C,F,H--132432054(+) AGGGCC/TTGAGT 1 -- int15Minor allele frequency- T:0.00NS EA NA 412
    rs1864217331,2
    C--132432169(+) CTGTCC/TGGTGG 1 -- int10--------
    rs287001311,2
    C,F--132432347(+) ATCTCG/CTATGT 1 -- int14Minor allele frequency- C:0.11NA WA 124
    rs1167030831,2
    F--132432368(+) CTACAG/ATATTT 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1483776401,2
    --132432403(+) ACTTAA/GTGTGA 1 -- int10--------
    rs1415543881,2
    --132432410(+) GTGACA/GTCTAC 1 -- int10--------
    rs598013421,2
    C--132432461(+) CTGAAG/AGCCGA 1 -- int14Minor allele frequency- A:0.06WA NA EA 360
    rs785668241,2
    C,F--132432472(+) ATCACA/GTTCCA 1 -- int11Minor allele frequency- G:0.06WA 118
    rs1920443201,2
    --132432586(+) CCCTGC/GTTTTA 1 -- int10--------
    rs1160685271,2
    C,F--132432602(+) TTGGGA/GTATCT 1 -- int11Minor allele frequency- G:0.04WA 118
    rs1827681211,2
    --132432736(+) GCAACC/TTCCGC 1 -- int10--------
    rs360811601,2
    C--132432841(+) TAGAGA/CCAGGG 1 -- int10--------
    rs1860134361,2
    --132432958(+) CCTACC/TTTTAA 1 -- int10--------
    rs1162698151,2
    C,F--132433017(+) TAACCG/AGCCTC 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1913070021,2
    --132433100(+) CCCTTA/CAGAGC 1 -- int10--------
    rs760559361,2
    C,F--132433121(+) AAAGGC/TAGCTT 1 -- int11Minor allele frequency- T:0.03NA 120
    rs756327681,2
    C,F--132433167(+) TTTCTC/TTATTT 1 -- int11Minor allele frequency- T:0.17WA 118
    rs1462461661,2
    C--132433199(+) CAGTC-/AGTG  
            
    AGCAT
    1 -- int10--------
    rs1400811741,2
    --132433261(+) CTCTCC/TGTGTG 1 -- int10--------
    rs1825654871,2
    --132433262(+) TCTCCA/GTGTGT 1 -- int10--------
    rs1427676521,2
    C--132433298(+) TCTGTA/GCCTCG 1 -- int10--------
    rs571680431,2
    C--132433549(+) TTTGGG/TAACTG 1 -- int16Minor allele frequency- T:0.06WA CSA NA EA 362
    rs1473751471,2
    --132433655(+) CTCTTG/TCTCCT 1 -- int10--------
    rs1390762181,2
    C--132433695(+) GGGGGC/TCTGGC 1 -- int10--------
    rs1871681821,2
    --132433708(+) AGGGGG/TCTTAG 1 -- int10--------
    rs1169147541,2
    C,F--132433768(+) ACTGTC/ACCCTC 1 -- int11Minor allele frequency- A:0.02NA 120
    rs1498849621,2
    --132433903(+) GGTATA/CCCTCA 1 -- int10--------
    rs1904894401,2
    --132434246(+) GGAACA/GGGCTC 1 -- int10--------
    rs1120953561,2
    C,F--132434267(+) TTAGGC/TGTTTC 1 -- int13Minor allele frequency- T:0.10CSA WA 121
    rs595183491,2
    C,F--132434288(+) GGGGCA/GGGAAG 1 -- int14Minor allele frequency- G:0.07WA NA 242
    rs1167942071,2
    C,F--132434303(+) GTTTGC/TGGTGG 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1829832081,2
    --132434346(+) GACGCA/GGCAGA 1 -- int10--------
    rs1448670181,2
    --132434387(+) CTAAAG/TGACAG 1 -- int10--------
    rs1134534201,2
    F--132434496(+) GGCTGT/CGCCAG 1 -- int11Minor allele frequency- C:0.00CSA 1
    rs781436581,2
    C,F--132434497(+) GCTGCG/CCCAGT 1 -- int11Minor allele frequency- C:0.29EA 120
    rs104417401,2
    C--132434513(+) AGAAGG/TGGGTG 1 -- int14Minor allele frequency- T:0.24WA NA EA 360
    rs580753871,2
    C--132434567(+) GTGACC/TGGGAA 1 -- int10--------
    rs736701551,2
    C,F--132434571(+) CCGGGA/GAGCCT 1 -- int16Minor allele frequency- G:0.06WA NA CSA EA 364
    rs1877138851,2
    --132434578(+) GCCTCC/GTGGGC 1 -- int10--------
    rs1467398551,2
    --132434641(+) GTTGTA/CCTCCT 1 -- int10--------
    rs109884681,2
    H--132434704(+) AGGTCA/CCACCG 1 -- int14Minor allele frequency- C:0.00NS EA 418
    rs1403300861,2
    --132434709(+) ACACCA/GTTCCC 1 -- int10--------
    rs1414296521,2
    C--132434879(+) GGGTT-/GGGGGG 1 -- int10--------
    rs284463601,2
    C,F--132434886(+) GGGGGG/TTTCTC 1 -- int110Minor allele frequency- T:0.23NA WA CSA EA 371
    rs1931171021,2
    --132435019(+) TTCCCC/TTCCTG 1 -- int10--------
    rs736367461,2
    C,F--132435071(+) TGCCCG/AGATGC 1 -- int12Minor allele frequency- A:0.21WA 120
    rs1843532891,2
    --132435078(+) ATGCAC/TGAGAG 1 -- int10--------
    rs105852521,2
    C,F--132435186(+) attca-/TTCA/ 
    TTCATTCA
    ttcat
    1 -- int12NA CSA 4
    rs1510674061,2
    C--132435277(+) GACTTC/GCAGTT 1 -- int10--------
    rs1139847941,2
    C,F--132435475(+) GTAATC/TCTAGC 1 -- int12Minor allele frequency- T:0.03NA EA 240
    rs1409651801,2
    --132435597(+) TGGGCA/GTGGTA 1 -- int10--------
    rs1501954441,2
    --132435628(+) CTACTC/TGGGAT 1 -- int10--------
    rs1876102251,2
    --132435688(+) CTGTGA/GTTACA 1 -- int10--------
    rs174173371,2
    C,F,H--132435832(+) TTTGTC/GGGTGA 1 -- int18Minor allele frequency- G:0.02NA NS EA 682
    rs1440490701,2
    C--132435932(+) CATGC-/CACA  
            
    CACAC
    1 -- int10--------
    rs1928298581,2
    --132435994(+) CAGCCC/TGGCCC 1 -- int10--------
    rs1387122651,2
    --132436042(+) GCAGCG/TGCTGG 1 -- int10--------
    rs1841330061,2
    --132436236(+) GTAGGG/TAGGTG 1 -- int10--------
    rs15505881,2
    H--132436267(+) TGGCAG/AAGCAT 1 -- int15Minor allele frequency- A:0.00NA NS EA 430
    rs1150557371,2
    F--132436307(+) CGGCTG/ACCCCT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1181074051,2
    C,F--132436335(+) ACCAGG/CACACC 1 -- int11Minor allele frequency- C:0.01NA 120
    rs1888511011,2
    --132436345(+) CCCGCC/TCTAGC 1 -- int10--------
    rs78581991,2
    C,F,A,H--132436381(+) ACCAGA/GTCCTG 1 -- int135Minor allele frequency- N:0.00EA NA NS WA CSA 3399
    rs1815216291,2
    --132436452(+) GAGCCC/GGGGTC 1 -- int10--------
    rs1490188331,2
    C--132436696(+) GGGGCA/GGTAGG 1 -- int10--------
    rs1471081571,2
    C--132436845(+) GAGAAA/GGAGGC 1 -- int10--------
    rs78591811,2
    C,F,A--132436893(+) CCCCCG/ACCCCC 1 -- int15Minor allele frequency- A:0.10NA WA 244
    rs78589561,2
    C,F,A,H--132436894(+) CCCCGC/TCCCCA 1 -- int17Minor allele frequency- T:0.33WA NA CSA EA 366
    rs1170849181,2
    F--132437156(+) CACTGC/TGTCAG 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1846671881,2
    --132437179(+) AGCTGA/GTGCGT 1 -- int10--------
    rs1384991621,2
    C--132437285(+) TGCTGC/TGGGCT 1 -- int10--------
    rs120026041,2
    C,F,H--132437333(+) GTTTAC/TCCGAG 1 -- int15Minor allele frequency- T:0.12NA WA CSA 216
    rs727702151,2
    C,F--132437356(+) CTCTCG/AAGGGG 1 -- int11Minor allele frequency- A:0.20EA 120
    rs727702171,2
    C,F--132437378(+) GGGCAG/AAGCTG 1 -- int12Minor allele frequency- A:0.04NA 122
    rs132830821,2
    C,F,H--132437413(+) TGGACC/TTGGAA 1 -- int14Minor allele frequency- T:0.03NS NA 234
    rs120026531,2
    C,F,H--132437420(+) GGAAGG/AGCCCG 1 -- int14Minor allele frequency- A:0.13WA NA CSA 126
    rs1904972861,2
    --132437600(+) GCCCAC/GGGGCG 1 -- int10--------
    rs357626771,2
    C,F--132437605(+) GGGGCG/TTGGAA 1 -- int14Minor allele frequency- T:0.09NA WA 242
    rs736367491,2
    C,F--132437723(+) CCCTGC/TTGAGC 1 -- int11Minor allele frequency- T:0.09WA 118
    rs1440065331,2
    --132437753(+) CCCTCC/TTGGCA 1 -- int10--------
    rs1822076671,2
    --132437792(+) ACCCTA/CCCTCC 1 -- int10--------
    rs1135598091,2
    C,F--132437926(+) CTGCCG/AGTCTC 1 -- int11Minor allele frequency- A:0.50NA 2
    rs792135761,2
    F--132437968(+) GCAGAC/TGTTTA 1 -- int11Minor allele frequency- T:0.11WA 118
    rs1175855261,2
    C,F--132437995(+) TTATTA/GAAAAT 1 -- int11Minor allele frequency- G:0.01NA 120
    rs78705561,2
    C,F,A--132438069(+) CCGCCA/GGGCGG 1 -- int14Minor allele frequency- G:0.24NA WA 124
    rs1907516471,2
    --132438076(+) GCGGGC/TGCGCC 1 -- int10--------
    rs801370341,2
    F--132438146(+) ACCCCG/ACAGAA 1 -- int11Minor allele frequency- A:0.09WA 118
    rs101201401,2
    C,F,A--132438152(+) CAGAAC/GGCCGA 1 -- int15Minor allele frequency- G:0.09NA WA 244
    rs1480092751,2
    --132438239(+) CCTCTA/TATGCT 1 -- int10--------
    rs342242251,2
    C,F--132438251(+) TCAAGA/GTGGTG 1 -- int14Minor allele frequency- G:0.04NA 126
    rs1163574711,2
    C,F--132438441(+) TTCACC/ACGCTC 1 -- int11Minor allele frequency- A:0.05WA 118
    rs78742271,2
    A--132438455(+) GCTGAC/GAGCCC 1 -- int10--------
    rs1810208671,2
    --132438461(+) AGCCCA/GTGTCT 1 -- int10--------
    rs1416622301,2
    --132438750(+) GGTTAC/TAGCTG 1 -- int10--------
    rs562991301,2
    C,F--132438826(+) AGCCCA/GTGTGC 1 -- int11Minor allele frequency- G:0.03NA 120
    rs1505210511,2
    --132439091(+) CCCCAA/GCTCAG 1 -- int10--------
    rs1853831941,2
    --132439374(+) CGCATG/TTGCGT 1 -- int10--------
    rs1394619431,2
    C--132439412(+) ATCCCA/GGTGAA 1 -- int10--------
    rs132946481,2
    C,F,A,H--132439457(+) GCACAG/AAGCGC 1 -- int116Minor allele frequency- A:0.06NS EA NA WA 1872
    rs746529911,2
    C,F--132439462(+) GAGCGC/ACCCCA 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1435143081,2
    --132439475(+) GATCCC/TGTTCT 1 -- int10--------
    rs1902419861,2
    --132439476(+) ATCCCA/GTTCTT 1 -- int10--------
    rs1827749311,2
    C--132439519(+) TGCAGA/GGCCTC 1 -- int10--------
    rs1462679891,2
    C--132439631(+) AAATAC/TGCAGT 1 -- int10--------
    rs1145793281,2
    C,F--132439704(+) CCGCGC/TGGGGT 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1884747341,2
    --132439728(+) GCAGCC/TTAGGC 1 -- int10--------
    rs1393757741,2
    --132439739(+) TCTGCC/TTCTGG 1 -- int10--------
    rs714994731,2
    C,F--132439768(+) GGGGGG/TGTTCC 1 -- int13Minor allele frequency- T:0.05NA 124
    rs1174375691,2
    F--132439785(+) CCTCCC/GGGTTC 1 -- int11Minor allele frequency- G:0.02NA 120
    rs1921072441,2
    --132439829(+) GCCCCA/CCTCCA 1 -- int10--------
    rs1839294121,2
    --132439876(+) TGGGCC/TGTGGC 1 -- int10--------
    rs1173276611,2
    F--132439906(+) CCAGGC/ACTTGC 1 -- int11Minor allele frequency- A:0.05EA 120
    rs1892124341,2
    --132440034(+) CACCAC/TATCCC 1 -- int10--------
    rs20090281,2
    C,F,A,H--132440042(-) CTCCCG/CCAGGG 1 -- int15Minor allele frequency- C:0.06NS NA WA 362
    rs1914072481,2
    --132440064(+) GGCTCA/TAAGCG 1 -- int10--------
    rs1838856151,2
    --132440068(+) CAAAGC/TGGGAA 1 -- int10--------
    rs2002661191,2
    --132440124(+) GGAAG-/GAAGAAAG 1 -- int10--------
    rs1384226251,2
    C--132440125(+) GAAGG-/AAGA  
            
    AAGAA
    1 -- int10--------
    rs3758541361,2
    C--132440237(+) TTCTT-/CTTTTT 1 -- int10--------
    rs132970551,2
    C,F--132440241(+) tctttC/Tttttt 1 -- int1 trp32Minor allele frequency- T:0.50NA 4
    rs1870941361,2
    --132440244(+) TTTTTC/TTTTTT 1 -- int10--------
    rs1918355611,2
    --132440279(+) ACTCTA/GTCGCC 1 -- int10--------
    rs1441090841,2
    C--132440323(+) CTACAA/GCCTCC 1 -- int10--------
    rs561177561,2
    C,F--132440328(+) ACCTCC/TGCCTC 1 -- int12Minor allele frequency- T:0.08WA NA 122
    rs20090041,2
    C,F,A--132440395(+) GTACCA/GCCATG 1 -- int15Minor allele frequency- G:0.30NA WA EA 362
    rs1392812141,2
    C--132440410(+) GCACA-/TTTTTG 1 -- int10--------
    rs1491755401,2
    --132440527(+) CGTGAA/GCCACT 1 -- int10--------
    rs1844247041,2
    C--132440550(+) GGGGGC/TGGCTT 1 -- int10--------
    rs714994741,2
    C,F--132440603(+) GAGGCC/ATTCTG 1 -- int13Minor allele frequency- A:0.13NA WA 122
    rs796406751,2
    F--132440674(+) AGGCAC/TAGGGG 1 -- int11Minor allele frequency- T:0.07WA 118
    rs714994751,2
    C,F--132440675(+) GGCACA/GGGGGC 1 -- int14Minor allele frequency- G:0.09NA WA 242
    rs7295241,2
    C,F,A,H--132440784(-) AAACCG/TTCCCT 1 -- int115Minor allele frequency- T:0.40NS EA NA WA CSA 793
    rs1423407351,2
    --132440865(+) GGGCAC/TGCCGG 1 -- int10--------
    rs1512551041,2
    --132440866(+) GGCACA/GCCGGG 1 -- int10--------
    rs1181371841,2
    F--132440936(+) GAAAGG/CGTGGG 1 -- int11Minor allele frequency- C:0.01NA 120
    rs714994761,2
    C,F--132440975(+) GCAGAC/GCTTGT 1 -- int13Minor allele frequency- G:0.05NA 124
    rs776915141,2
    C,F--132440991(+) GTGTGT/CGACTT 1 -- int11Minor allele frequency- C:0.03EA 120
    rs1899949211,2
    --132441045(+) GTCCAC/GAGTGG 1 -- int10--------
    rs7295231,2
    C,F,A,H--132441078(-) GAGAGC/AGCCCC 1 -- int114Minor allele frequency- A:0.45EA NS NA WA CSA 670
    rs1415267901,2
    --132441138(+) TGACAC/GTTGTG 1 -- int10--------
    rs1821576581,2
    --132441263(+) CAGATC/TCTCAG 1 -- int10--------
    rs1855463921,2
    --132441335(+) ACGTCA/GCAGTC 1 -- int10--------
    rs560473991,2
    C,F--132441366(+) CACCAA/GTCAGG 1 -- int13Minor allele frequency- G:0.08WA NA 240
    rs1470266581,2
    --132441440(+) GTGTCA/GGGGAC 1 -- int10--------
    rs601938571,2
    C,F--132441569(+) GAATGG/AAGGGA 1 -- int13Minor allele frequency- A:0.09WA NA 240
    rs1385605321,2
    --132441694(+) TTATTC/GTGCAC 1 -- int10--------
    rs70298161,2
    C,F,A,H--132441746(+) TCCTCC/GCAAAC 1 -- int126Minor allele frequency- G:0.39NS EA NA WA CSA 2774
    rs1144043311,2
    F--132441806(+) TGAGGC/TCCAGG 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1907495461,2
    --132441838(+) ACGTGG/TGGGCA 1 -- int10--------
    rs604416841,2
    C,F--132441860(+) GCTCTT/GGACTG 1 -- int13Minor allele frequency- G:0.09WA NA 240
    rs108195551,2
    C,F,A,H--132441917(+) GACTGC/TGACCT 1 -- int16Minor allele frequency- T:0.29NA WA EA 364
    rs1425880861,2
    --132441979(+) AACGCC/TGGAGC 1 -- int10--------
    rs1502484231,2
    --132442087(+) TGCAGA/GCAGAG 1 -- int10--------
    rs1807834001,2
    --132442096(+) AGAAAC/TGTAGA 1 -- int10--------
    rs1851498801,2
    --132442150(+) GTTTCC/TCAGGG 1 -- int10--------
    rs1385783151,2
    --132442191(+) GCTGTA/GGAGAT 1 -- int10--------
    rs736701671,2
    C,F--132442216(+) AGCTCC/TACTTG 1 -- int11Minor allele frequency- T:0.50WA 2
    rs797438521,2
    C,F--132442257(+) CTGAGC/GCTCAA 1 -- int11Minor allele frequency- G:0.38EA 120
    rs1494967451,2
    --132442441(+) TTTGGA/GAGGCT 1 -- int10--------
    rs78615531,2
    C,F--132442527(+) AATACG/AAAGTT 1 -- int14Minor allele frequency- A:0.06NA WA 242
    rs1812187921,2
    --132442549(+) GTGGCA/GTGCAC 1 -- int10--------
    rs132935821,2
    C,F--132442566(+) tcccaA/Gctact 1 -- int12Minor allele frequency- G:0.25NA 4
    rs1868200371,2
    --132442603(+) TGAACA/CTGGGA 1 -- int10--------
    rs132940561,2
    C,F--132442612(+) gaggcG/Agaggt 1 -- int12Minor allele frequency- A:0.25NA 4
    rs1915351331,2
    --132442642(+) GCCACC/TGCACT 1 -- int10--------
    rs78615771,2
    C,F--132442677(+) TCCGTC/TTCAAA 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1838381621,2
    --132442691(+) AAAAAA/GAAAAG 1 -- int10--------
    rs132942181,2
    C--132442696(+) AAAAAA/GAAAAG 1 -- int1 trp31Minor allele frequency- G:0.00WA 2
    rs579938491,2
    C--132442696(+) AAAAA-/AA    
       
    /G/GA
    AAAGA
    1 -- int11NA 2
    rs2010009751,2
    C--132442696(+) AAAAA-/GAAAAG 1 -- int10--------
    rs117885751,2
    C,F,A,H--132442748(+) TCCCAC/TCCCCC 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1154422301,2
    C,F--132442987(+) AGCCCG/ACACAC 1 -- int11Minor allele frequency- A:0.09WA 118
    rs1422150061,2
    C--132443102(+) TGTGA-/CCCCC 
            
    CCGCC
    1 -- int10--------
    rs1911597351,2
    C--132443105(+) TGACCA/GCCACT 1 -- int10--------
    rs782275901,2
    C,F--132443112(+) CACTCC/GTGTGC 1 -- int11Minor allele frequency- G:0.09WA 118
    rs78624171,2
    C,F,A,H--132443251(+) ATTACA/GACATC 1 -- int120Minor allele frequency- G:0.34EA NA NS WA CSA 1006
    rs3682278151,2
    F,H--132443251(+) ATTAC-/A/GACATC 1 -- int112NS EA 1978
    rs1821442741,2
    --132443278(+) AAGACA/GACCTT 1 -- int10--------
    rs64789131,2
    C,F,A,H--132443331(+) TGCAGA/GTGGGT 1 -- int128Minor allele frequency- N:0.01NS EA NA WA CSA 1746
    rs1868755461,2
    --132443460(+) TGCTGG/TCTCCT 1 -- int10--------
    rs611152881,2
    F--132443613(+) GGCCAA/GCATGG 1 -- int10--------
    rs1441442391,2
    --132443617(+) AACATA/GGCAAA 1 -- int10--------
    rs1830402031,2
    --132443723(+) GAACCC/TGGGAG 1 -- int10--------
    rs714974821,2
    C--132443798(+) ATTTC-/AAAAAA 1 -- int11Minor allele frequency- A:0.50NA 2
    rs1505746971,2
    --132443804(+) AAAAAA/CAAACA 1 -- int10--------
    rs1884569391,2
    --132443809(+) AAAACA/GGAAAG 1 -- int10--------
    rs1395569971,2
    --132443960(+) AACCCA/GCCCTC 1 -- int10--------
    rs78660701,2
    C,F,A,H--132444099(+) AATGCA/GTCTCC 1 -- int129Minor allele frequency- G:0.46NA NS EA WA CSA 2906
    rs782060751,2
    C,F--132444107(+) TCCTTC/TGGCAC 1 -- int11Minor allele frequency- T:0.08WA 118
    rs1928622191,2
    --132444196(+) GTTTGC/TTGCTT 1 -- int10--------
    rs1498071771,2
    --132444238(+) GAAGCA/GTATGG 1 -- int10--------
    rs744277571,2
    F--132444265(+) AGAATT/ATTCCT 1 -- int11Minor allele frequency- A:0.08WA 118
    rs736701681,2
    C,F--132444363(+) ATGCCC/TGTGGC 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1891939261,2
    --132444470(+) TTTCCC/TTCAAC 1 -- int10--------
    rs1926039711,2
    --132444590(+) TCCCCA/GCCGCT 1 -- int10--------
    rs351193321,2
    C--132444610(+) CGCAC-/TATGTTA 1 -- int10--------
    rs30547641,2
    C--132444611(+) GCACT-/ATGTTAC 1 -- int10--------
    rs2001517111,2
    C--132444611(-) TAACAG/TAGTGC 1 -- int10--------
    rs1161640311,2
    C,F--132444641(+) TATTCG/ACAACT 1 -- int11Minor allele frequency- A:0.08WA 118
    rs736276091,2
    C,F--132445008(+) GTGGCG/AGGGTC 1 -- int12Minor allele frequency- A:0.17WA 120
    rs1396998791,2
    C--132445207(+) GTGAA-/CCCCCC 1 -- int10--------
    rs2011773371,2
    --132445471(+) AGGAA-/CCCCTC 1 -- int10--------
    rs1169457141,2
    F--132445523(+) AGGAAG/ACCCCC 1 -- int11Minor allele frequency- A:0.01EA 120
    rs1834732741,2
    --132445574(+) CTTTAC/TAGACA 1 -- int10--------
    rs1882010721,2
    --132445584(+) AGATAC/TTGACA 1 -- int10--------
    rs70326791,2
    C,F,A,H--132445642(+) TTTCTT/GGAGAG 1 -- int16Minor allele frequency- G:0.04NS EA NA WA 542
    rs1810057081,2
    C--132445807(+) CAGGAA/GATCGA 1 -- int10--------
    rs117902481,2
    C,F,H--132445810(+) gagatC/Tgagac 1 -- int14Minor allele frequency- T:0.33NA 12
    rs1863315031,2
    --132446019(+) AAAAAA/TAAATA 1 -- int10--------
    rs586350401,2
    C,F--132446031(+) AAAATA/TAAAAA 1 -- int12Minor allele frequency- T:0.13WA 120
    rs736701691,2
    C,F--132446073(+) TAAATC/G/TCCACC 1 -- int13WA NA 240
    rs46108581,2
    C,F,A,H--132446440(+) TTCTGC/TCAGGG 1 -- int117Minor allele frequency- T:0.46EA NS NA WA CSA 884
    rs1899495951,2
    --132446486(+) ATTATA/GTCAGT 1 -- int10--------
    rs1399454881,2
    --132446548(+) AACTAA/GGATAT 1 -- int10--------
    rs1469717431,2
    C--132446671(+) TAGAG-/GAGACACA
    CACACAGAGA
    GAGAC
    1 -- int10--------
    rs1492217501,2
    --132446674(+) AGGAG-/ACAC  
            
    ACACA
    1 -- int10--------
    rs1996146781,2
    --132446691(+) AGAGA-/GACACA 1 -- int10--------
    rs30547911,2
    C,A--132446737(+) CACACA/CCCCAA 1 -- int10--------
    rs713854531,2
    C--132446738(+) cacac-/ACA/  
     ACCC
    /CC
    ccaac
    2 -- int1 cds11NA 2
    rs24171441,2
    C,F,A,H--132446739(+) cacacC/Acaaca 1 -- int12Minor allele frequency- A:0.50WA CSA 4
    rs24171461,2
    H--132446748(+) cagaaA/Cagata 1 -- int14Minor allele frequency- C:0.00NS EA 388
    rs713854541,2
    C--132446762(+) AAATC-/CAACACA 1 -- int11Minor allele frequency- CA:0.00NA 2
    rs1124655421,2
    C--132446795(+) CACACC/ACACAC 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs48374001,2
    A--132446797(+) CACACA/CCACAC 1 -- int10--------
    rs78490661,2
    C,A,H--132446803(+) CACACA/CCACAC 1 -- int12Minor allele frequency- C:0.25NA WA 4
    rs736701711,2
    C,F--132446926(+) TGGCCG/AAGGCC 1 -- int13Minor allele frequency- A:0.08WA NA 240
    rs736701721,2
    C,F--132446938(+) GGGCTG/CTGTGG 1 -- int13Minor allele frequency- C:0.09WA NA 240
    rs1426662191,2
    C--132447027(+) ACTCAC/TGTTTA 1 -- int10--------
    rs589426401,2
    C,F--132447028(+) CTCACG/ATTTAT 1 -- int11Minor allele frequency- A:0.02EA 120
    rs109884691,2
    C,F,H--132447093(+) TGTCTC/Aaccta 1 -- int19Minor allele frequency- A:0.05NS EA NA WA 1208
    rs1433929781,2
    C--132447104(+) ATCACA/GGAGGG 1 -- int10--------
    rs1816691621,2
    --132447136(+) ATAGAC/TGAGGC 1 -- int10--------
    rs775507951,2
    C,F--132447216(+) CATTCC/TGGGGT 1 -- int11Minor allele frequency- T:0.03NA 120
    rs1870203291,2
    C--132447233(+) GTCAAC/TCATGA 1 -- int10--------
    rs109884701,2
    C,F,H--132447329(+) CCACTG/AACGCC 1 -- int15Minor allele frequency- A:0.03NS EA WA 526
    rs1513079231,2
    C--132447387(+) GCCCCA/GTGGGC 1 -- int10--------
    rs1405435841,2
    --132447445(+) GTTCCA/CAGCAC 1 -- int10--------
    rs1909206281,2
    --132447559(+) GTATGC/TGGAGC 1 -- int10--------
    rs727702201,2
    C--132447658(+) TTTATC/TTTTTT 1 -- int10--------
    rs1851459631,2
    --132447672(+) GCAGGA/GTCTCA 1 -- int10--------
    rs108195561,2
    C,F,A,H--132447715(+) ATCACA/GGCTCA 1 -- int17Minor allele frequency- G:0.47NA WA CSA 17
    rs559996271,2
    C,F--132447750(+) TTGATC/TCTCCC 1 -- int13Minor allele frequency- T:0.10WA CSA 122
    rs1386061331,2
    --132447773(+) TGAGTA/CGCTGG 1 -- int10--------
    rs1898399861,2
    C--132447913(+) CACTGC/GGCCCG 1 -- int10--------
    rs589938841,2
    --132447914(+) ACTGCA/GCCCGG 1 -- int10--------
    rs101198981,2
    C,F--132447918(+) cgcccG/AgccAG 1 -- int11Minor allele frequency- A:0.06WA 118
    rs101259911,2
    C,F,A,H--132448019(+) GTATTA/GTGCAC 1 -- int123Minor allele frequency- N:0.01EA NA NS WA CSA 1102
    rs714994781,2
    C,F--132448091(+) AGCACC/TGACAA 1 -- int13Minor allele frequency- T:0.04NA 124
    rs614175831,2
    C,F--132448163(+) AGTGTA/GAGCAA 1 -- int12Minor allele frequency- G:0.17WA 120
    rs349616341,2
    C,F--132448190(+) TGGAGT/CGGCTG 1 -- int13Minor allele frequency- C:0.33NA 6
    rs1998022651,2
    C--132448198(+) CTGGGA/GGACGT 1 -- int10--------
    rs1495436591,2
    C--132448206(+) CGTGGC/TCAGAC 1 -- int10--------
    rs1441260261,2
    --132448251(+) CCTACA/GGGAAG 1 -- int10--------
    rs1170954341,2
    F--132448316(+) AAGTCT/CTCCAG 1 -- int11Minor allele frequency- C:0.02NA 120
    rs1829658761,2
    --132448495(+) GCTCCC/GCTTCT 1 -- int10--------
    rs1179813541,2
    C,F--132448539(+) GAGGGG/CAGTGA 1 -- int11Minor allele frequency- C:0.07EA 120
    rs1486811671,2
    --132448737(+) CCTTCC/TGCCTC 1 -- int10--------
    rs30024591,2
    H--132448933(+) ttacaG/Tgctac 1 -- int14Minor allele frequency- T:0.00NS EA 420
    rs1879198701,2
    --132448951(+) ACACAC/TAGCTG 1 -- int10--------
    rs1146233771,2
    F--132449111(+) AGAAAA/CTACTC 1 -- int11Minor allele frequency- C:0.01WA 118