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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PRRG4 Gene

protein-coding   GIFtS: 48
GCID: GC11P032808

Proline Rich Gla (G-Carboxyglutamic Acid) 4 (Transmembrane)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Proline Rich Gla (G-Carboxyglutamic Acid) 4 (Transmembrane)1 2
PRGP42 3 5
TMG42 3 5
Proline-Rich Gamma-Carboxyglutamic Acid Protein 42 3
Proline-Rich Gla Protein 42 3
Transmembrane Gamma-Carboxyglutamic Acid Protein 42

External Ids:    HGNC: 307991   Entrez Gene: 790562   Ensembl: ENSG000001353787   OMIM: 6116905   UniProtKB: Q9BZD63   

Export aliases for PRRG4 gene to outside databases

Previous GC identifer: GC11P032545


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for PRRG4 Gene: 
PRRG4 (proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)) is a protein-coding gene. Diseases associated with PRRG4 include wagr syndrome, and aniridia. GO annotations related to this gene include molecular_function and calcium ion binding. An important paralog of this gene is PRRG1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PRRG4 gene promoter:
         AML1a   GATA-3   POU3F1   AP-2gamma   GATA-2   GATA-1   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRRG4 promoter sequence
   Search SABiosciences Chromatin IP Primers for PRRG4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRRG4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p13   Ensembl cytogenetic band:  11p13   HGNC cytogenetic band: 11p13

PRRG4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRRG4 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P032808:  view genomic region     (about GC identifiers)

Start:
32,851,481 bp from pter      End:
32,879,669 bp from pter
Size:
28,189 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TMG4_HUMAN, Q9BZD6 (See protein sequence)
Recommended Name: Transmembrane gamma-carboxyglutamic acid protein 4 precursor  
Size: 226 amino acids; 25403 Da
Subcellular location: Membrane; Single-pass type I membrane protein

Explore the universe of human proteins at neXtProt for PRRG4: NX_Q9BZD6

Explore proteomics data for PRRG4 at MOPED 

Post-translational modifications:

  • UniProtKB: Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent
    gamma-carboxylase
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BZD6

  • PRRG4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PRRG4 Protein Expression
    REFSEQ proteins: NP_076986.1  
    ENSEMBL proteins: 
     ENSP00000257836  

    Human Recombinant Protein Products for PRRG4: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PRRG4 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005794Golgi apparatus IDA--
    GO:0016021integral to membrane NAS11171957

    PRRG4 for ontologies           About GeneDecksing



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    Assay Products for PRRG4: 
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    Cloud-Clone Corp. CLIAs for PRRG4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR017857 Coagulation_fac_subgr_Gla_dom
     IPR000294 GLA_domain

    Graphical View of Domain Structure for InterPro Entry Q9BZD6

    ProtoNet protein and cluster: Q9BZD6

    2 Blocks protein domains:
    IPB000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
    IPB002383 Coagulation factor GLA domain signature


    UniProtKB/Swiss-Prot: TMG4_HUMAN, Q9BZD6
    Similarity: Contains 1 Gla (gamma-carboxy-glutamate) domain


    PRRG4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005509calcium ion binding IEA--
         
    PRRG4 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PRRG4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PRRG4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRRG4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRRG4 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRRG4
    8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate PRRG4 (see all 47):
    hsa-miR-142-5p hsa-miR-607 hsa-miR-106a hsa-miR-4272 hsa-miR-519a hsa-miR-371-5p hsa-miR-548l hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidPRRG4 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of PRRG4 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRRG4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRRG4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for PRRG4 (Q9BZD63 ENSP000002578364) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APPBP2Q926243I2D: score=1 
    AOC3ENSP000003123264STRING: ENSP00000312326
    ENSG00000228299ENSP000003978674STRING: ENSP00000397867
    HDAC1ENSP000003626494STRING: ENSP00000362649
    RBBP8ENSP000003230504STRING: ENSP00000323050
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    PRRG4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PRRG4 (TMG4)

    Search CenterWatch for drugs/clinical trials and news about PRRG4 / TMG4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PRRG4 gene: 
    NM_024081.5  

    Unigene Cluster for PRRG4:

    Proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
    Hs.471695  [show with all ESTs]
    Unigene Representative Sequence: NM_024081
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000257836(uc001mtx.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRRG4
    8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate PRRG4 (see all 47):
    hsa-miR-142-5p hsa-miR-607 hsa-miR-106a hsa-miR-4272 hsa-miR-519a hsa-miR-371-5p hsa-miR-548l hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidPRRG4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for PRRG4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRRG4
    Clone
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    OriGene clones in human, mouse for PRRG4 (see all 7)
    OriGene ORF clones in mouse, rat for PRRG4
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRRG4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRRG4
    Sirion Biotech Customized lentivirus for stable overexpression of PRRG4 
                         Customized lentivirus expression plasmids for stable overexpression of PRRG4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PRRG4
    OriGene qSTAR qPCR primer pairs in human, mouse for PRRG4
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRRG4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRRG4

    Additional mRNA sequence: 

    AF326351.1 BC010052.2 BC063393.1 BC063641.1 

    5 DOTS entries:

    DT.91658742  DT.65285731  DT.40210034  DT.75154120  DT.100697610 

    16 AceView cDNA sequences:

    NM_024081 BC010052 BC063393 AF326351 BX283870 CD631894 BE732028 CF146146 
    BX414772 AA225023 CD631891 AA169396 CF146386 BG533045 AI475201 CD631895 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PRRG4 expression in normal human tissues (normalized intensities)      PRRG4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    PRRG4 Expression
    About this image


    PRRG4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Stem Cell line 5
     
     Uterus (Reproductive System)
             cervix   

    See PRRG4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PRRG4

    SOURCE GeneReport for Unigene cluster: Hs.471695

    UniProtKB/Swiss-Prot: TMG4_HUMAN, Q9BZD6
    Tissue specificity: Expressed in lung, liver, kidney, pancreas and placenta

        SABiosciences Custom PCR Arrays for PRRG4
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRRG4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for PRRG4 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prrg41 , 5 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)1, 5 80.74(n)1
    75.11(a)1
      2 (54.98 cM)5
    2284131  NM_178695.51  NP_848810.31 
     1048307415 
    chicken
    (Gallus gallus)
    Aves PRRG41 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 61.21(n)
    53.18(a)
      421600  NM_001199415.1  NP_001186344.1 
    lizard
    (Anolis carolinensis)
    Reptilia PRRG46
    proline rich Gla (G-carboxyglutamic acid) 4 (trans...
    55(a)
    1 ↔ 1
    1(61371743-61387513)
    zebrafish
    (Danio rerio)
    Actinopterygii prrg41 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 56.45(n)
    53.76(a)
      550330  NM_001017637.1  NP_001017637.1 


    ENSEMBL Gene Tree for PRRG4 (if available)
    TreeFam Gene Tree for PRRG4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PRRG4 gene
    PRRG12  PRRG22  PRRG32  
    1 SIMAP similar gene for PRRG4 using alignment to 1 protein entry:     TMG4_HUMAN:
    PRRG2

    PRRG4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/566 SNPs in PRRG4 are shown (see all 566)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1807124151,2
    --32849561(+) AGTTTA/CGACCA 1 -- us2k10--------
    rs1504075811,2
    C--32849567(+) GACCAC/TGAGGT 1 -- us2k10--------
    rs122774871,2
    C,F--32849752(+) AAAAAT/CTGAAT 1 -- us2k12Minor allele frequency- C:0.06CSA WA 120
    rs127884811,2
    C,F--32849777(+) AggccG/Aggcac 1 -- us2k14Minor allele frequency- A:0.09NA WA 242
    rs1853373041,2
    --32849849(+) CAGGAA/GTTTGA 1 -- us2k10--------
    rs79424221,2
    C--32849860(+) GAACAG/ACCTGG 1 -- us2k18Minor allele frequency- A:0.07NA WA CSA 14
    rs1491591931,2
    --32849912(+) TTAGCC/TGGGCG 1 -- us2k10--------
    rs110320111,2
    C,F--32849970(+) agaatC/Tgcttg 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1392356691,2
    --32849971(+) GAATCG/TCTTGA 1 -- us2k10--------
    rs1120587051,2
    C--32850181(+) ATAAAG/AAAGGA 1 -- us2k12Minor allele frequency- A:0.06CSA WA 120

    HapMap Linkage Disequilibrium report for PRRG4 (32851481 - 32879669 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for PRRG4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2659576CNV Deletion23128226
    nsv825818CNV Loss20364138
    nsv897191CNV Gain21882294
    nsv897190CNV Gain21882294
    esv34742CNV Gain17911159
    dgv1064n71CNV Gain21882294
    essv7540CNV CNV17122850
    essv6421CNV CNV17122850

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611690    OMIM disorders: --

    3 diseases for PRRG4:    About MalaCards
    wagr syndrome    aniridia    mental retardation

    1 disease from the University of Copenhagen DISEASES database for PRRG4:
    WAGR syndrome

    PRRG4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PRRG4

    Export disorders for PRRG4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PRRG4 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with PRRG4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of two novel transmembrane gamma-carboxyglutamic acid proteins expressed broadly in fetal and adult tissues. (PubMed id 11171957)1, 2, 3, 9 Kulman J.D.... Davie E.W. (2001)
    2. Genomewide association study for onset age in Parkins on disease. (PubMed id 19772629)1, 4 Latourelle J.C....Foroud T. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    5. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. Characterization of 11p14-p12 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism. (PubMed id 19096215)9 Xu S....Fan Y.S. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79056 HGNC: 30799 AceView: PRRG4 Ensembl:ENSG00000135378 euGenes: HUgn79056
    ECgene: PRRG4 H-InvDB: PRRG4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PRRG4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PRRG4 gene:
    Search GeneIP for patents involving PRRG4

    GeneCards and IP:
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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