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PRRG3 Gene

protein-coding   GIFtS: 47
GCID: GC0XP150863

Proline Rich Gla (G-Carboxyglutamic Acid) 3 (Transmembrane)

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Proline Rich Gla (G-Carboxyglutamic Acid) 3 (Transmembrane)1 2
PRGP32 3 5
TMG32 3 5
Proline-Rich Gamma-Carboxyglutamic Acid Protein 32 3
Proline-Rich Gla Protein 32 3
Transmembrane Gamma-Carboxyglutamic Acid Protein 32

External Ids:    HGNC: 307981   Entrez Gene: 790572   Ensembl: ENSG000001300327   OMIM: 3006855   UniProtKB: Q9BZD73   

Export aliases for PRRG3 gene to outside databases

Previous GC identifers: GC0XP150537 GC0XP139720


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PRRG3 Gene:
This gene encodes a protein which contains a vitamin K-dependent carboxylation/gamma-carboxyglutamic domain. The
encoded protein is a member of a family of vitamin K-dependent transmembrane proteins which contain a
glutamate-rich extracellular domain. (provided by RefSeq, Aug 2011)

GeneCards Summary for PRRG3 Gene:
PRRG3 (proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)) is a protein-coding gene. Diseases associated with PRRG3 include myopia. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is PRRG4.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011681.17  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PRRG3 gene promoter:
         RFX1   MAZR   AML1a   Arnt   GATA-1   CREB   deltaCREB   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRRG3 promoter sequence
   Search Chromatin IP Primers for PRRG3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRRG3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

PRRG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRRG3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP150863:  view genomic region     (about GC identifiers)

Start:
150,863,596 bp from pter      End:
150,874,396 bp from pter
Size:
10,801 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TMG3_HUMAN, Q9BZD7 (See protein sequence)
Recommended Name: Transmembrane gamma-carboxyglutamic acid protein 3 precursor  
Size: 231 amino acids; 25875 Da
Secondary accessions: A1A523 A1A575 Q8N2N6

Explore the universe of human proteins at neXtProt for PRRG3: NX_Q9BZD7

Explore proteomics data for PRRG3 at MOPED

Post-translational modifications: 

  • Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent
    gamma-carboxylase1
  • Modification sites at neXtProt

  • See PRRG3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_076987.3  
    ENSEMBL proteins: 
     ENSP00000411509   ENSP00000359379   ENSP00000359378   ENSP00000394121   ENSP00000440217  

    PRRG3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for PRRG3

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    Abcam antibodies for PRRG3
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    LSBio Antibodies in human, mouse, rat for PRRG3

    PRRG3 Assay Products:

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    Cloud-Clone Corp. ELISAs for PRRG3
    Cloud-Clone Corp. CLIAs for PRRG3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR017857 Coagulation_fac_subgr_Gla_dom
     IPR000294 GLA_domain

    Graphical View of Domain Structure for InterPro Entry Q9BZD7

    ProtoNet protein and cluster: Q9BZD7

    2 Blocks protein domains:
    IPB000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
    IPB002383 Coagulation factor GLA domain signature


    UniProtKB/Swiss-Prot: TMG3_HUMAN, Q9BZD7
    Similarity: Contains 1 Gla (gamma-carboxy-glutamate) domain


    PRRG3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    PRRG3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRRG3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRRG3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRRG3

    miRNA
    Products:
        
    miRTarBase miRNAs that target PRRG3:
    hsa-mir-26b-5p (MIRT028930)

    Block miRNA regulation of human, mouse, rat PRRG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PRRG3 (see all 15):
    hsa-miR-549 hsa-miR-3173-3p hsa-miR-2052 hsa-miR-19b-2* hsa-miR-196a* hsa-miR-575 hsa-miR-1271 hsa-miR-944
    SwitchGear 3'UTR luciferase reporter plasmidPRRG3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for PRRG3
    Predesigned siRNA for gene silencing in human, mouse, rat PRRG3

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for PRRG3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRRG3 (NM_024082)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRRG3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRRG3

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRRG3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TMG3_HUMAN, Q9BZD7: Membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    cytosol1
    endoplasmic reticulum1
    golgi apparatus1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0016021integral component of membrane NAS11171957

    PRRG3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRRG3
    Interactions:

        Search GeneGlobe Interaction Network for PRRG3

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    PRRG3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRRG3 (TMG3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PRRG3 gene: 
    NM_024082.3  

    Unigene Cluster for PRRG3:

    Proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
    Hs.592236  [show with all ESTs]
    Unigene Representative Sequence: NR_033262
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000448726 ENST00000370354 ENST00000370353(uc004few.2) ENST00000448324
    ENST00000538575(uc022cgt.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PRRG3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PRRG3 (see all 15):
    hsa-miR-549 hsa-miR-3173-3p hsa-miR-2052 hsa-miR-19b-2* hsa-miR-196a* hsa-miR-575 hsa-miR-1271 hsa-miR-944
    SwitchGear 3'UTR luciferase reporter plasmidPRRG3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PRRG3
    Predesigned siRNA for gene silencing in human, mouse, rat PRRG3
    Clone
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    OriGene clones in human, mouse for PRRG3 (see all 5)
    OriGene ORF clones in mouse, rat for PRRG3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRRG3 (NM_024082)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRRG3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRRG3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for PRRG3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRRG3
      QuantiTect SYBR Green Assays in human, mouse, rat PRRG3
      QuantiFast Probe-based Assays in human, mouse, rat PRRG3

    Additional mRNA sequence: 

    AF326350.1 AK074574.1 BC128256.1 BC128409.1 NR_033262.1 

    2 DOTS entries:

    DT.97837501  DT.97837500 

    Selected AceView cDNA sequences (see all 38):

    AI266282 AF326350 F04401 AA327671 F10103 AI803684 BM695741 AI810564 
    AW593171 AI658907 BU742702 AI279649 AK074574 BM674939 AA974755 BM717745 
    AA410454 BI492647 AA772897 AK125352 CD631899 BM728785 AA885337 NM_024082 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for PRRG3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b
    SP1:        -                                       
    SP2:                    -           -               


    ECgene alternative splicing isoforms for PRRG3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PRRG3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGTACCGGG
    PRRG3 Expression
    About this image

    PRRG3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRRG3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.592236

    UniProtKB/Swiss-Prot: TMG3_HUMAN, Q9BZD7
    Tissue specificity: Expressed in brain, lung, kidney and heart

        Custom PCR Arrays for PRRG3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRRG3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for PRRG3 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prrg31 , 5 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)1, 5 87.3(n)1
    94.37(a)1
      X (37.15 cM)5
    2087481  NM_001081135.11  NP_001074604.11 
     719626245 
    chicken
    (Gallus gallus)
    Aves PRRG31 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 75.92(n)
    77.53(a)
      422291  XM_004940730.1  XP_004940787.1 
    lizard
    (Anolis carolinensis)
    Reptilia PRRG36
    proline rich Gla (G-carboxyglutamic acid) 3 (trans...
    63(a)
    1 ↔ 1
    GL343376.1(1034464-1039954)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia prrg31 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 65.37(n)
    63.11(a)
      100495175  XM_002939202.2  XP_002939248.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5632901 transmembrane gamma-carboxyglutamic acid protein 3-like 60.85(n)
    57.55(a)
      563290  XM_686654.4  XP_691746.4 


    ENSEMBL Gene Tree for PRRG3 (if available)
    TreeFam Gene Tree for PRRG3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PRRG3 gene
    PRRG42  PRRG12  PRRG22  
    12 SIMAP similar genes for PRRG3 using alignment to 4 protein entries:     TMG3_HUMAN (see all proteins):
    PROZ    PROC    F10    PROC1    PRRG1    F2
    F9    PROS1    F9 p22    factor IX F9    GAS6    PRRG2

    PRRG3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PRRG3 (see all 192)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1831722731,2
    --150728131(+) AAGGTA/CAGGAA 1 -- us2k10--------
    rs1871399881,2
    --150728342(+) CCTGCA/GAGACC 1 -- us2k10--------
    rs1903556751,2
    --150728367(+) TCATGC/TGCACT 1 -- us2k10--------
    rs1452079561,2
    C--150728475(+) GAAGCC/TAAAGT 1 -- us2k10--------
    rs1829525761,2
    --150728572(+) CTATGA/CGGTGT 1 -- us2k10--------
    rs556728651,2
    C,F--150728811(+) AGAGGG/CAGGCA 1 -- us2k11Minor allele frequency- C:0.00WA 2
    rs1875719211,2
    --150728822(+) TCGGGA/GGAGCT 1 -- us2k10--------
    rs1932467711,2
    --150728845(+) CCCTGA/GGGGTT 1 -- us2k10--------
    rs1857536441,2
    --150728861(+) GGAGGC/TGGCCG 1 -- us2k10--------
    rs1405719161,2
    --150728870(+) CGGTGA/GCAATG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PRRG3 (150863596 - 150874396 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for PRRG3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv7156CNV Insertion18451855

    Locus Specific Mutation Databases (LSDB): PRRG3

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PRRG3
    DNA2.0 Custom Variant and Variant Library Synthesis for PRRG3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300685    OMIM disorders: --

    1 disease for PRRG3:    
    About MalaCards
    myopia


    PRRG3 for disorders           About GeneDecksing


    Export disorders for PRRG3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PRRG3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with PRRG3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of two novel transmembrane gamma-carboxyglutamic acid proteins expressed broadly in fetal and adult tissues. (PubMed id 11171957)1, 2, 3, 9 Kulman J.D.... Davie E.W. (Proc. Natl. Acad. Sci. U.S.A. 2001)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (DNA Res. 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. (PubMed id 15203218)1 Fu G.K....Stuve L.L. (Genomics 2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79057 HGNC: 30798 AceView: PRRG3 Ensembl:ENSG00000130032 euGenes: HUgn79057
    ECgene: PRRG3 H-InvDB: PRRG3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PRRG3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PRRG3 gene:
    Search GeneIP for patents involving PRRG3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for PRRG3  
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     Block miRNA regulation of human, mouse, rat PRRG3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PRRG3
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     Search Tocris compounds for PRRG3 (TMG3)
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     Novus Tissue Slides
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