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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PRRC2A Gene

protein-coding   GIFtS: 49
GCID: GC06P031719

Proline-Rich Coiled-Coil 2A

(Previous name: HLA-B associated transcript 2)
(Previous symbol: BAT2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Proline-Rich Coiled-Coil 2A1 2     G22 3
BAT21 2 3 5     HLA-B-Associated Transcript 22 3
HLA-B Associated Transcript 21 2     D6S51E2 5
Large Proline-Rich Protein BAT22 3     D6S512
Proline-Rich And Coiled-Coil-Containing Protein 2A2 3     Protein PRRC2A2
Protein G22 3     

External Ids:    HGNC: 139181   Entrez Gene: 79162   Ensembl: ENSG000002044697   OMIM: 1425805   UniProtKB: P486343   

Export aliases for PRRC2A gene to outside databases

Previous GC identifers: GC06P031374 GC06P031592 GC06P031594 GC06P031600


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PRRC2A Gene:
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These
genes are all within the human major histocompatibility complex class III region. This gene has microsatellite
repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly
thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development
of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants
encoding the same protein have been found for this gene. (provided by RefSeq, Dec 2010)

GeneCards Summary for PRRC2A Gene: 
PRRC2A (proline-rich coiled-coil 2A) is a protein-coding gene. Diseases associated with PRRC2A include coronary artery aneurysm, and rheumatoid arthritis. GO annotations related to this gene include protein binding. An important paralog of this gene is PRRC2C.

UniProtKB/Swiss-Prot: PRC2A_HUMAN, P48634
Function: May play a role in the regulation of pre-mRNA splicing

Gene Wiki entry for PRRC2A (BAT2) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NT_113891.2  NT_167245.1  NT_167246.1  NT_167247.1  NT_167248.1  NT_167249.1  
NC_018917.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for PRRC2A
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRRC2A promoter sequence
   Search SABiosciences Chromatin IP Primers for PRRC2A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRRC2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.3

PRRC2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRRC2A gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P031719:  view genomic region     (about GC identifiers)

Start:
31,588,450 bp from pter      End:
31,605,554 bp from pter
Size:
17,105 bases      Orientation:
plus strand

6 alternative locations:
Chr6+,NT_167245 2,874,022-2,891,126      Chr6+,NT_167247 2,968,140-2,985,242      Chr6+,NT_167249 2,919,253-2,936,356     
Chr6+,NT_113891.2 3,098,067-3,115,170      Chr6+,NT_167246 2,931,334-2,948,438      Chr6+,NT_167248 2,882,091-2,899,191     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PRC2A_HUMAN, P48634 (See protein sequence)
Recommended Name: Protein PRRC2A  
Size: 2157 amino acids; 228863 Da
Subcellular location: Cytoplasm. Nucleus
Developmental stage: Broadly expressed during the 11th week of gestation, with highest levels in the central
nervous system, spinal ganglia, osteoblasts and osteocytes (at protein level)
Sequence caution: Sequence=AAA35585.1; Type=Frameshift; Positions=38, 58; Sequence=AAA35586.1; Type=Frameshift;
Positions=38, 58; Sequence=BAE06116.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=CAA78744.1; Type=Frameshift; Positions=38, 58;
Secondary accessions: B0UX77 B0UZE9 B0UZL3 O95875 Q05BK4 Q4LE37 Q5SQ29 Q5SQ30 Q5ST84 Q5STX6
Q5STX7 Q68DW9 Q6P9P7 Q6PIN1 Q8MGQ9 Q96QC6
Alternative splicing: 4 isoforms:  P48634-1   P48634-2   P48634-3   P48634-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for PRRC2A: NX_P48634

Explore proteomics data for PRRC2A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P48634

  • PRRC2A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PRRC2A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_004629.3  NP_542417.2  

    ENSEMBL proteins: 
     ENSP00000365175   ENSP00000365201  

    Human Recombinant Protein Products for PRRC2A: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    PRRC2A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR009738 BAT2_N

    Graphical View of Domain Structure for InterPro Entry P48634

    ProtoNet protein and cluster: P48634


    PRRC2A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PRC2A_HUMAN, P48634
    Function: May play a role in the regulation of pre-mRNA splicing

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16713569
         
    PRRC2A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PRRC2A:
     Increased cell death in breast 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PRRC2A 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRRC2A 
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    miRNA
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    miRTarBase miRNAs that target PRRC2A:
    hsa-let-7b (MIRT005234)

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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate PRRC2A:
    hsa-miR-495 hsa-miR-300 hsa-miR-381
    SwitchGear 3'UTR luciferase reporter plasmidPRRC2A 3' UTR sequence
    Inhib. RNA
    Products:
        
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRRC2A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/40 Interacting proteins for PRRC2A (P486341, 2, 3 ENSP000003651754) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542531, 2, 3, ENSP000002447694EBI-347545,EBI-930964 MINT-2864423 MINT-2856362 MINT-2864404 MINT-2864442 I2D: score=3 STRING: ENSP00000244769
    C1QBPQ070212, 3, ENSP000002256984MINT-62735 MINT-62637 MINT-62811 I2D: score=5 STRING: ENSP00000225698
    CCR10P460922, 3, ENSP000003325044MINT-62802 MINT-62628 MINT-62726 I2D: score=5 STRING: ENSP00000332504
    FGAP026712, 3, ENSP000003063614MINT-62623 MINT-62721 MINT-62797 I2D: score=5 STRING: ENSP00000306361
    IMMTQ168912, 3, ENSP000003872624MINT-62725 MINT-62627 MINT-62801 I2D: score=5 STRING: ENSP00000387262
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PRRC2A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PRRC2A (PRC2A)

    1 PharmGKB related drug/compound annotation for PRRC2A gene    About this table
    Drug/compound PharmGKB Annotation
    carbamazepineCA  

    Search CenterWatch for drugs/clinical trials and news about PRRC2A / PRC2A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PRRC2A gene (2 alternative transcripts): 
    NM_004638.3  NM_080686.2  

    Unigene Cluster for PRRC2A:

    Proline-rich coiled-coil 2A
    Hs.436093  [show with all ESTs]
    Unigene Representative Sequence: NM_004638
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376007(uc011dnv.1 uc003nvb.4) ENST00000469577 ENST00000376033(uc003nvc.4)
    ENST00000464079 ENST00000464890 ENST00000483470 ENST00000460302 ENST00000484787
    ENST00000469501 ENST00000487089 ENST00000487839 ENST00000492691 ENST00000462617
    ENST00000482441
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRRC2A
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate PRRC2A:
    hsa-miR-495 hsa-miR-300 hsa-miR-381
    SwitchGear 3'UTR luciferase reporter plasmidPRRC2A 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRRC2A
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    Additional mRNA sequence: 

    AB210034.1 AF075059.1 AK297210.1 AK298584.1 AK302756.1 AK309774.1 BC030127.1 BC032134.2 
    BC042295.1 BC050408.1 BC060668.1 CR749245.1 M33509.1 

    24/30 DOTS entries (see all 30):

    DT.95319619  DT.95350369  DT.97763962  DT.92412731  DT.95228022  DT.100039278  DT.92453850  DT.92453852 
    DT.121406434  DT.91833257  DT.91833692  DT.92416778  DT.95173136  DT.97860787  DT.121406453  DT.121406464 
    DT.86857378  DT.95173133  DT.100811214  DT.100039277  DT.100798869  DT.100823013  DT.100823014  DT.121406444 

    5 AceView cDNA sequences:

    BE302895 BI019233 BE389143 BE278011 BG827834 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PRRC2A expression in normal human tissues (normalized intensities)      PRRC2A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTAGACTCAC
    PRRC2A Expression
    About this image


    PRRC2A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Atrioventricular Canal Cells Atrioventricular Canal
             Outflow Tract

    See PRRC2A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PRRC2A

    SOURCE GeneReport for Unigene cluster: Hs.436093

    UniProtKB/Swiss-Prot: PRC2A_HUMAN, P48634
    Tissue specificity: Limited to cell-lines of leukemic origin

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRRC2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PRRC2A gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prrc2a1 , 5 proline-rich coiled-coil 2A1, 5 88.49(n)1
    90.59(a)1
      17 (18.59 cM)5
    537611  NM_001199044.11  NP_001185973.11 
     351490765 
    lizard
    (Anolis carolinensis)
    Reptilia PRRC2A6
    Uncharacterized protein
    53(a)
    1 ↔ 1
    2(193947910-193978099)
    African clawed frog
    (Xenopus laevis)
    Amphibia bat2-prov2 HLA-B associated transcript 2 78.47(n)    BC051009.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nfkbil12 nuclear factor of kappa light polypeptide gene enhancer more 81.03(n)   394248  BC055180.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F52G3.16
    Protein F52G3.1
    15(a)
    1 → many
    X(16963869-16972820)


    ENSEMBL Gene Tree for PRRC2A (if available)
    TreeFam Gene Tree for PRRC2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PRRC2A gene
    PRRC2C2  PRRC2B2  
    1 SIMAP similar gene for PRRC2A using alignment to 2 protein entries:     PRC2A_HUMAN (see all proteins):
    BAT2L

    PRRC2A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/669 SNPs in PRRC2A are shown (see all 669)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0357974
    A breast cancer sample4--see VAR_0357972 R H mis40--------
    VAR_0357964
    A breast cancer sample4--see VAR_0357962 T I mis40--------
    rs1909528121,2
    --31586529(+) GTGGCA/GTGATC 2 -- us2k10--------
    rs93917301,2
    C,F--31586603(+) gctgaG/Aactac 2 -- us2k12Minor allele frequency- A:0.50NA 4
    rs30912801,2
    C--31586742(+) ctacaG/Agcata 2 -- us2k14Minor allele frequency- A:0.45NA CSA EA 244
    rs69347191,2
    C--31586761(+) cgcccA/GgccTC 2 -- us2k10--------
    rs1831591691,2
    --31586777(+) TCTTAA/GTAAGA 2 -- us2k10--------
    rs779153891,2
    C--31586783(+) TAAGAG/ATTTTT 2 -- us2k12Minor allele frequency- A:0.05WA 120
    rs556930601,2
    C--31586827(+) CATATC/TTTATT 2 -- us2k10--------
    rs2018390111,2
    C--31586840(+) TCTAC-/TTCT  
            
    TTCTT
    2 -- us2k10--------

    HapMap Linkage Disequilibrium report for PRRC2A (31588450 - 31605554 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for PRRC2A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv830627CNV Loss17160897
    dgv6581n71CNV Loss21882294
    nsv884423CNV Loss21882294
    nsv462871CNV Loss19166990
    nsv884418CNV Gain21882294


    Human Gene Mutation Database (HGMD): PRRC2A
    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for PRRC2A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 142580    OMIM disorders: --

    17 diseases for PRRC2A:    About MalaCards
    coronary artery aneurysm    rheumatoid arthritis    diabetes mellitus    arthritis
    pancreatitis    non-hodgkin lymphoma    hodgkin's lymphoma    ulcerative colitis
    malaria    colon adenocarcinoma    type 1 diabetes    systemic lupus erythematosus
    asthma    lupus erythematosus    myocardial infarction    obesity
    adenocarcinoma


    PRRC2A for disorders           About GeneDecksing


    Export disorders for PRRC2A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PRRC2A gene, integrated from 9 sources (see all 66):
    (articles sorted by number of sources associating them with PRRC2A)
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    1. A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. (PubMed id 2156268)1, 2, 3, 9 Banerji J.... Spies T. (1990)
    2. Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. (PubMed id 8499947)1, 2, 3 Iris F.J.M....Cohen D. (1993)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. Antibodies generated by a novel DNA vaccination identify the MHC class III encoded BAT2 polypeptide. (PubMed id 15752841)1, 2 Schneiders A.... Koch N. (2005)
    5. Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. (PubMed id 14667819)1, 2 Lehner B....Sanderson C.M. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PubMed id 14656967)1, 2 Xie T.... Hood L. (2003)
    8. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    9. A comprehensive family-based replication study of schi zophrenia genes. (PubMed id 23894747)1 Aberg K.A....van den Oord E.J. (2013)
    10. Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25. 1 regions identifies functional and histology-specific lung cancer susceptibilit y loci in African-Americans. (PubMed id 23221128)1 Walsh K.M....Amos C.I. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7916 HGNC: 13918 AceView: BAT2.5 Ensembl:ENSG00000204469 euGenes: HUgn7916
    ECgene: PRRC2A H-InvDB: PRRC2A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PRRC2A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PRRC2A gene:
    Search GeneIP for patents involving PRRC2A

    GeneCards and IP:
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