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Aliases for PRR35 Gene

Aliases for PRR35 Gene

  • Proline Rich 35 2 3 5
  • C16orf11 3 4
  • Chromosome 16 Open Reading Frame 11 2
  • Uncharacterized Protein RJD1 4
  • LA16c-366D1.2 3

External Ids for PRR35 Gene

Previous HGNC Symbols for PRR35 Gene

  • C16orf11

Summaries for PRR35 Gene

GeneCards Summary for PRR35 Gene

PRR35 (Proline Rich 35) is a Protein Coding gene. An important paralog of this gene is ZNF750.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR35 Gene

Genomics for PRR35 Gene

Genomic Location for PRR35 Gene

Chromosome:
16
Start:
560,422 bp from pter
End:
565,529 bp from pter
Size:
5,108 bases
Orientation:
Plus strand

Genomic View for PRR35 Gene

Genes around PRR35 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRR35 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRR35 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR35 Gene

No data available for Regulatory Elements for PRR35 Gene

Proteins for PRR35 Gene

  • Protein details for PRR35 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG20-PRR35_HUMAN
    Recommended name:
    Proline-rich protein 35
    Protein Accession:
    P0CG20
    Secondary Accessions:
    • B8ZZ27
    • Q8N233
    • Q96AX3
    • Q96S23

    Protein attributes for PRR35 Gene

    Size:
    571 amino acids
    Molecular mass:
    59354 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK61234.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for PRR35 Gene

Proteomics data for PRR35 Gene at MOPED

Post-translational modifications for PRR35 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRR35 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PRR35 Gene

Domains & Families for PRR35 Gene

Protein Domains for PRR35 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR35: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRR35 Gene

Function for PRR35 Gene

genes like me logo Genes that share phenotypes with PRR35: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR35 Gene

Localization for PRR35 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PRR35 Gene

Pathways & Interactions for PRR35 Gene

SuperPathways for PRR35 Gene

No Data Available

Interacting Proteins for PRR35 Gene

Gene Ontology (GO) - Biological Process for PRR35 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRR35 Gene

Drugs & Compounds for PRR35 Gene

No Compound Related Data Available

Transcripts for PRR35 Gene

mRNA/cDNA for PRR35 Gene

(1) REFSEQ mRNAs :
(7) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PRR35 Gene

No ASD Table

Relevant External Links for PRR35 Gene

GeneLoc Exon Structure for
PRR35
ECgene alternative splicing isoforms for
PRR35

Expression for PRR35 Gene

mRNA expression in normal human tissues for PRR35 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for PRR35 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR35 Gene



genes like me logo Genes that share expression patterns with PRR35: view

Protein tissue co-expression partners for PRR35 Gene

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PRR35 Gene

Orthologs for PRR35 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PRR35 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C25H16orf11 35
  • 77.23 (n)
  • 71.33 (a)
C16orf11 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C6H16orf11 35
  • 77.8 (n)
  • 72.23 (a)
C16orf11 36
  • 70 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C16H16orf11 35
  • 98.48 (n)
  • 97.55 (a)
C16orf11 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC302999 35
  • 74.72 (n)
  • 69.23 (a)
oppossum
(Monodelphis domestica)
Mammalia C16orf11 36
  • 29 (a)
OneToOne
mouse
(Mus musculus)
Mammalia A930017K11Rik 36
  • 65 (a)
OneToOne
chicken
(Gallus gallus)
Aves C16orf11 36
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C16orf11 36
  • 38 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.13681 35
zebrafish
(Danio rerio)
Actinopterygii C24H16orf11 36
  • 25 (a)
OneToOne
Species with no ortholog for PRR35:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PRR35 Gene

ENSEMBL:
Gene Tree for PRR35 (if available)
TreeFam:
Gene Tree for PRR35 (if available)

Paralogs for PRR35 Gene

Paralogs for PRR35 Gene

genes like me logo Genes that share paralogs with PRR35: view

Variants for PRR35 Gene

Sequence variations from dbSNP and Humsavar for PRR35 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1010761 -- 564,821(+) ACCCG(A/G)GCCCT reference, synonymous-codon
rs4984890 -- 562,698(+) CAGAT(C/T)GGCAG intron-variant
rs7190861 -- 559,106(+) GCCGG(A/G)CCGGG upstream-variant-2KB
rs7190878 -- 559,130(+) TGCTG(A/G)GCTCT upstream-variant-2KB
rs7202618 -- 564,028(+) GCCCC(C/T)GGCCA reference, missense

Variation tolerance for PRR35 Gene

Gene Damage Index Score: 3.92; 59.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR35 Gene

HapMap Linkage Disequilibrium report
PRR35

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PRR35 Gene

Disorders for PRR35 Gene

Relevant External Links for PRR35

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRR35

No disorders were found for PRR35 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR35 Gene

Publications for PRR35 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for PRR35 Gene

Sources for PRR35 Gene

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