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Aliases for PRR34 Gene

Aliases for PRR34 Gene

  • Proline Rich 34 2 3 5
  • C22orf26 3 4
  • Chromosome 22 Open Reading Frame 26 2
  • Proline-Rich Protein 34 3

External Ids for PRR34 Gene

Previous HGNC Symbols for PRR34 Gene

  • C22orf26

Summaries for PRR34 Gene

GeneCards Summary for PRR34 Gene

PRR34 (Proline Rich 34) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR34 Gene

Genomics for PRR34 Gene

Regulatory Elements for PRR34 Gene

Enhancers for PRR34 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F046022 0.2 ENCODE 12.6 +30.3 30277 1.8 KLF17 ZIC2 HIC1 ZNF664 ZFHX2 ZNF157 ZNF366 FOS EGR2 NRF1 LINC00899 LOC642648 PRR34-AS1 ENSG00000231010 PRR34 MIR4763 MIRLET7A3 MIRLET7B MIRLET7BHG ENSG00000273145
GH22F046005 1.4 FANTOM5 Ensembl ENCODE 12.5 +43.5 43504 9.7 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF548 FOS LINC00899 RPS10P31 ENSG00000273243 LOC642648 MIRLET7A3 MIR4763 MIRLET7B MIRLET7BHG PRR34 PRR34-AS1
GH22F046000 0.8 Ensembl ENCODE 12 +51.3 51344 4.4 BCOR TBP CTCF KLF17 ZMYM3 ZIC2 RAD21 ZFHX2 GLIS2 ZBTB48 LINC00899 MIRLET7A3 LOC642648 MIR4763 MIRLET7B MIRLET7BHG PRR34 PRR34-AS1 ENSG00000231010 GC22M045913
GH22F045514 0.8 Ensembl ENCODE 7.2 +537.1 537106 4.7 CTCF KLF1 TEAD4 SIN3A CEBPG ZIC2 RAD21 TEAD3 ZFHX2 CTBP1 PRR34 GC22P045526 FBLN1
GH22F045509 1.3 Ensembl ENCODE 6.7 +542.4 542366 4.1 BHLHE40 ZMYM3 ZNF623 ZIC2 NR2F2 ZFHX2 GLIS2 ZNF366 SMARCA4 ZNF157 RIBC2 SMC1B PRR34 LINC00899 PPARA FBLN1 GC22P045526
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around PRR34 on UCSC Golden Path with GeneCards custom track

Genomic Location for PRR34 Gene

46,049,478 bp from pter
46,054,144 bp from pter
4,667 bases
Minus strand

Genomic View for PRR34 Gene

Genes around PRR34 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRR34 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRR34 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR34 Gene

Proteins for PRR34 Gene

  • Protein details for PRR34 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Proline-rich protein 34
    Protein Accession:
    Secondary Accessions:
    • B0QZ24

    Protein attributes for PRR34 Gene

    138 amino acids
    Molecular mass:
    14718 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRR34 Gene

Post-translational modifications for PRR34 Gene

No Post-translational modifications

Other Protein References for PRR34 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PRR34 Gene

Domains & Families for PRR34 Gene

Protein Domains for PRR34 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR34: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRR34 Gene

Function for PRR34 Gene

genes like me logo Genes that share phenotypes with PRR34: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR34 Gene

Localization for PRR34 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PRR34 Gene

Pathways & Interactions for PRR34 Gene

SuperPathways for PRR34 Gene

No Data Available

Interacting Proteins for PRR34 Gene

Gene Ontology (GO) - Biological Process for PRR34 Gene


No data available for Pathways by source and SIGNOR curated interactions for PRR34 Gene

Transcripts for PRR34 Gene

mRNA/cDNA for PRR34 Gene

(1) REFSEQ mRNAs :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRR34 Gene

No ASD Table

Relevant External Links for PRR34 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PRR34 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PRR34 Gene

Protein differential expression in normal tissues from HIPED for PRR34 Gene

This gene is overexpressed in Colon muscle (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR34 Gene

Protein tissue co-expression partners for PRR34 Gene

NURSA nuclear receptor signaling pathways regulating expression of PRR34 Gene:

genes like me logo Genes that share expression patterns with PRR34: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PRR34 Gene

Orthologs for PRR34 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for PRR34 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C22orf26 35
  • 99 (a)
Species where no ortholog for PRR34 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR34 Gene

Gene Tree for PRR34 (if available)
Gene Tree for PRR34 (if available)

Paralogs for PRR34 Gene

No data available for Paralogs for PRR34 Gene

Variants for PRR34 Gene

Sequence variations from dbSNP and Humsavar for PRR34 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs111688790 -- 46,051,171(+) GGCGG(A/G)CAATG utr-variant-3-prime
rs112380771 -- 46,055,089(+) AATGA(C/T)TATAA intron-variant, upstream-variant-2KB
rs112405410 -- 46,054,012(+) GTTGG(A/C/G)GGGGG intron-variant, reference, missense
rs112837617 -- 46,055,322(+) TGTGA(A/G)TCTGG intron-variant, upstream-variant-2KB
rs112938439 -- 46,053,356(+) CCAAT(A/T)TAAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for PRR34 Gene

Variant ID Type Subtype PubMed ID
dgv2469n106 OTHER inversion 24896259
dgv776n67 CNV gain 20364138
dgv777n67 CNV gain 20364138
nsv1152661 OTHER inversion 26484159
nsv471212 CNV loss 18288195
nsv829281 CNV gain 20364138
nsv829285 CNV gain 20364138
nsv829289 CNV loss 20364138

Variation tolerance for PRR34 Gene

Gene Damage Index Score: 2.52; 43.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR34 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRR34 Gene

Disorders for PRR34 Gene

Relevant External Links for PRR34

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PRR34 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR34 Gene

Publications for PRR34 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 4 64

Products for PRR34 Gene

Sources for PRR34 Gene

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