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Aliases for PRR33 Gene

Aliases for PRR33 Gene

  • Proline Rich 33 2 3
  • C11orf89 3 4
  • Chromosome 11 Open Reading Frame 89 2

External Ids for PRR33 Gene

Previous HGNC Symbols for PRR33 Gene

  • C11orf89

Previous GeneCards Identifiers for PRR33 Gene

  • GC11M001887

Summaries for PRR33 Gene

GeneCards Summary for PRR33 Gene

PRR33 (Proline Rich 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR33 Gene

Genomics for PRR33 Gene

Genomic Location for PRR33 Gene

Chromosome:
11
Orientation:
Unknown strand

Genomic View for PRR33 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for PRR33 Gene

Proteins for PRR33 Gene

  • Protein details for PRR33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MZF0-PRR33_HUMAN
    Recommended name:
    Proline-rich protein 33
    Protein Accession:
    A8MZF0
    Secondary Accessions:
    • A6NI49

    Protein attributes for PRR33 Gene

    Size:
    331 amino acids
    Molecular mass:
    35187 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRR33 Gene

Post-translational modifications for PRR33 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRR33 Gene

Domains & Families for PRR33 Gene

Protein Domains for PRR33 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR33: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRR33 Gene

Function for PRR33 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR33 Gene

Localization for PRR33 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRR33 gene
Compartment Confidence
nucleus 3
cytosol 3
extracellular 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PRR33 Gene

Pathways & Interactions for PRR33 Gene

SuperPathways for PRR33 Gene

No Data Available

Interacting Proteins for PRR33 Gene

Gene Ontology (GO) - Biological Process for PRR33 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRR33 Gene

Transcripts for PRR33 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for PRR33 Gene

No ASD Table

Relevant External Links for PRR33 Gene

ECgene alternative splicing isoforms for
PRR33

No data available for mRNA/cDNA for PRR33 Gene

Expression for PRR33 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PRR33 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR33 Gene



NURSA nuclear receptor signaling pathways regulating expression of PRR33 Gene:

PRR33
genes like me logo Genes that share expression patterns with PRR33: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for PRR33 Gene

Orthologs for PRR33 Gene

This gene was present in the common ancestor of mammals.

Orthologs for PRR33 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC102153419 34
  • 74.86 (n)
cow
(Bos Taurus)
Mammalia LOC789200 34
  • 73.59 (n)
rat
(Rattus norvegicus)
Mammalia LOC685580 34
  • 71.94 (n)
Species where no ortholog for PRR33 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

No data available for Evolution for PRR33 Gene

Paralogs for PRR33 Gene

No data available for Paralogs for PRR33 Gene

Variants for PRR33 Gene

Variation tolerance for PRR33 Gene

Gene Damage Index Score: 6.69; 78.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR33 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRR33

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for PRR33 Gene

Disorders for PRR33 Gene

No disorders were found for PRR33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for PRR33 Gene

Publications for PRR33 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64
  2. Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk. (PMID: 25342443) LindstrAPm S. … Tamimi R.M. (Nat Commun 2014) 3 64
  3. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K. … Easton D.F. (Nat. Genet. 2013) 3 64
  4. Genome-wide association study identifies novel breast cancer susceptibility loci. (PMID: 17529967) Easton D.F. … Ponder B.A. (Nature 2007) 3 64

Products for PRR33 Gene

Sources for PRR33 Gene

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