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Aliases for PRR31 Gene

Aliases for PRR31 Gene

  • Proline Rich 31 2 3 5
  • C9orf141 3 4
  • Chromosome 9 Open Reading Frame 141 2
  • Proline-Rich Protein 31 3

External Ids for PRR31 Gene

Previous HGNC Symbols for PRR31 Gene

  • C9orf141

Summaries for PRR31 Gene

GeneCards Summary for PRR31 Gene

PRR31 (Proline Rich 31) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR31 Gene

Genomics for PRR31 Gene

Regulatory Elements for PRR31 Gene

Enhancers for PRR31 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G136990 1.7 FANTOM5 Ensembl ENCODE 12.8 +27.1 27130 10.9 HDGF PKNOX1 CREB3L1 ARNT AGO1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 LCN12 ABCA2 ANAPC2 PRR31 C9orf139 SNHG7 LCNL1 RABL6 CCDC183 LOC100418938
GH09G136787 1.7 Ensembl ENCODE dbSUPER 11.3 -174.2 -174173 14.2 MLX AGO1 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC MEF2D LCN8 ABCA2 NALT1 LCN10 TMEM141 LCN12 PRR31 C8G FBXW5 DPH7
GH09G136881 1.6 Ensembl ENCODE dbSUPER 11.7 -86.2 -86224 2.7 HDGF PKNOX1 FOXA2 MLX AGO1 ARID4B SIN3A DMAP1 YY1 SLC30A9 PHPT1 MAMDC4 C9orf172 TMEM141 LCN12 PRR31 FBXW5 C8G RABL6 C9orf139
GH09G136925 1.3 Ensembl ENCODE dbSUPER 12.3 -41.6 -41635 3.5 HDGF CTCF PKNOX1 ESRRA RAD21 FOSL1 ZFHX2 ZNF316 GATA2 POLR2A LCN12 TRAF2 CCDC183 PRR31 MAMDC4 PHPT1 C9orf172 RABL6 CCDC183-AS1 LCNL1
GH09G136884 1.3 ENCODE dbSUPER 11.7 -82.6 -82612 3.1 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZBTB7B ZNF207 ZNF143 FOS PHPT1 SNHG7 MAMDC4 C9orf172 FBXW5 C8G LCN12 TMEM141 PRR31 CCDC183-AS1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PRR31 on UCSC Golden Path with GeneCards custom track

Genomic Location for PRR31 Gene

Chromosome:
9
Start:
136,968,886 bp from pter
End:
136,976,820 bp from pter
Size:
7,935 bases
Orientation:
Plus strand

Genomic View for PRR31 Gene

Genes around PRR31 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRR31 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRR31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR31 Gene

Proteins for PRR31 Gene

  • Protein details for PRR31 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5SQ13-PRR31_HUMAN
    Recommended name:
    Proline-rich protein 31
    Protein Accession:
    Q5SQ13

    Protein attributes for PRR31 Gene

    Size:
    230 amino acids
    Molecular mass:
    24070 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRR31 Gene

Post-translational modifications for PRR31 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRR31 Gene

No data available for DME Specific Peptides for PRR31 Gene

Domains & Families for PRR31 Gene

Protein Domains for PRR31 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR31: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRR31 Gene

Function for PRR31 Gene

Phenotypes for PRR31 Gene

genes like me logo Genes that share phenotypes with PRR31: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR31 Gene

Localization for PRR31 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRR31 gene
Compartment Confidence
mitochondrion 2
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PRR31 Gene

Pathways & Interactions for PRR31 Gene

SuperPathways for PRR31 Gene

No Data Available

Interacting Proteins for PRR31 Gene

Gene Ontology (GO) - Biological Process for PRR31 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRR31 Gene

Drugs & Compounds for PRR31 Gene

No Compound Related Data Available

Transcripts for PRR31 Gene

mRNA/cDNA for PRR31 Gene

(6) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PRR31 Gene

No ASD Table

Relevant External Links for PRR31 Gene

GeneLoc Exon Structure for
PRR31
ECgene alternative splicing isoforms for
PRR31

Expression for PRR31 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PRR31 Gene

Protein differential expression in normal tissues from HIPED for PRR31 Gene

This gene is overexpressed in Heart (41.1) and Urinary Bladder (25.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR31 Gene



Protein tissue co-expression partners for PRR31 Gene

NURSA nuclear receptor signaling pathways regulating expression of PRR31 Gene:

PRR31
genes like me logo Genes that share expression patterns with PRR31: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRR31 Gene

Orthologs for PRR31 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for PRR31 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C9orf141 35
  • 97 (a)
OneToOne
Species where no ortholog for PRR31 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR31 Gene

ENSEMBL:
Gene Tree for PRR31 (if available)
TreeFam:
Gene Tree for PRR31 (if available)

Paralogs for PRR31 Gene

No data available for Paralogs for PRR31 Gene

Variants for PRR31 Gene

Sequence variations from dbSNP and Humsavar for PRR31 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000331556 -- 136,968,939(+) GAGAA(C/T)TGGGC utr-variant-5-prime
rs1002139358 -- 136,972,853(+) CCCCC(A/G)CGACC utr-variant-3-prime
rs1002170411 -- 136,972,751(+) CTGAG(A/G)ACGCT utr-variant-3-prime
rs1002361859 -- 136,970,559(+) GCAGG(C/T)GGGTG intron-variant
rs1002412440 -- 136,970,775(+) CCAGT(A/G)AGAAC intron-variant

Variation tolerance for PRR31 Gene

Gene Damage Index Score: 5.31; 70.53% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR31 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRR31

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PRR31 Gene

Disorders for PRR31 Gene

No disorders were found for PRR31 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for PRR31 Gene

Publications for PRR31 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans. (PMID: 23328707) Tin A. … Kao W.H. (Nephrol. Dial. Transplant. 2013) 3 64

Products for PRR31 Gene

Sources for PRR31 Gene

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